feat(#669): add custom Warfarin content

app/CONTRIBUTING.md

@@ -141,11 +141,49 @@ shown below.
 
 ```dart
 // TODO(after-testing): remove test data adaption
-UserData.instance.diplotypes!['CYP2D6'] = Diplotype(
-  gene: 'CYP2D6',
-  resultType: 'Diplotype',
-  genotype: '*18/*143',
-  phenotype: 'Poor Metabolizer',
-  allelesTested: '*xN.*3.*4.*5.*6.*8.*9.*10.*14A.*14B.*17.*18.*41.*143',
-);
+  UserData.instance.diplotypes!['CYP2D6'] = Diplotype(
+    gene: 'CYP2D6',
+    resultType: 'Diplotype',
+    genotype: '*18/*143',
+    phenotype: 'Poor Metabolizer',
+    allelesTested: '',
+  );
+```
+
+You can use the CPIC API to get reasonable genotype-phenotype pairings, e.g.,
+with
+`https://api.cpicpgx.org/v1/diplotype?genesymbol=eq.CYP2C9&select=genesymbol,diplotype,generesult`.
+
+Some more examples are collected below (this is for testing what is shown for
+Warfarin):
+
+```dart
+  UserData.instance.diplotypes!['CYP2C9'] = Diplotype(
+    gene: 'CYP2C9',
+    resultType: 'Diplotype',
+    genotype: '*11/*13',
+    phenotype: 'Poor Metabolizer',
+    allelesTested: '',
+  );
+  UserData.instance.diplotypes!['VKORC1'] = Diplotype(
+    gene: 'VKORC1',
+    resultType: 'Diplotype',
+    genotype: '-1639G>A variant carriers',
+    phenotype: '-1639G>A variant carriers',
+    allelesTested: '',
+  );
+  UserData.instance.diplotypes!['CYP4F2'] = Diplotype(
+    gene: 'CYP4F2',
+    resultType: 'Diplotype',
+    genotype: 'rs2108622 T carriers',
+    phenotype: 'rs2108622 T carriers',
+    allelesTested: '',
+  );
+  UserData.instance.diplotypes!['CYP2C'] = Diplotype(
+    gene: 'CYP2C',
+    resultType: 'Diplotype',
+    genotype: 'rs12777823 A carriers',
+    phenotype: 'rs12777823 A carriers',
+    allelesTested: '',
+  );
 ```

app/lib/drug/pages/drug.dart

@@ -52,39 +52,19 @@ class DrugPage extends StatelessWidget {
           child: Column(
             crossAxisAlignment: CrossAxisAlignment.start,
             children: [
-              DrugAnnotationCard(
+              DrugAnnotationCards(
                 drug,
                 isActive: drug.isActive,
                 setActivity: ({ value }) =>
                   context.read<DrugCubit>().setActivity(drug, value),
                 disabled: loading,
               ),
               SizedBox(height: PharMeTheme.mediumSpace),
-              SubHeader(
-                context.l10n.drugs_page_header_guideline,
-                tooltip: _buildGuidelineTooltipText(context),
-              ),
-              SizedBox(height: PharMeTheme.smallSpace),
               GuidelineAnnotationCard(drug),
             ],
           ),
         ),
       ],
     );
   }
-
-  String _buildGuidelineTooltipText(BuildContext context) {
-    return drug.userGuideline != null
-      ? context.l10n.drugs_page_tooltip_guideline(
-          drug.userGuideline!.externalData.first.source
-        )
-      : drug.userOrFirstGuideline != null
-        // Guideline for drug is present but not for genotype
-        ? context.l10n.drugs_page_tooltip_missing_guideline_for_drug_or_genotype(
-            context.l10n.drugs_page_tooltip_missing_genotype
-          )
-        : context.l10n.drugs_page_tooltip_missing_guideline_for_drug_or_genotype(
-            context.l10n.drugs_page_tooltip_missing_drug
-          );
-  }
 }

app/lib/drug/widgets/annotation_cards/drug.dart

@@ -1,8 +1,8 @@
 import '../../../common/module.dart';
 import '../sub_header.dart';
 
-class DrugAnnotationCard extends StatelessWidget {
-  const DrugAnnotationCard(
+class DrugAnnotationCards extends StatelessWidget {
+  const DrugAnnotationCards(
     this.drug, {
     required this.isActive,
     required this.setActivity,

app/lib/drug/widgets/annotation_cards/guideline.dart

@@ -3,53 +3,112 @@ import 'package:url_launcher/url_launcher.dart';
 import '../../../common/module.dart';
 import '../module.dart';
 
+enum WarfarinContent {
+  tooltip,
+  implication,
+  recommendation,
+  color,
+  icon,
+}
+
+final warfarinProperties = <WarfarinContent, dynamic Function(BuildContext)>{
+  WarfarinContent.tooltip: (context) =>
+    context.l10n.drugs_page_tooltip_warfarin,
+  WarfarinContent.implication: (context) =>
+    context.l10n.drugs_page_implication_warfarin,
+  WarfarinContent.recommendation: (context) =>
+    context.l10n.drugs_page_recommendation_warfarin,
+  WarfarinContent.color: (_) => WarningLevel.none.color,
+  WarfarinContent.icon: (_) => WarningLevel.none.icon,
+};
+
 class GuidelineAnnotationCard extends StatelessWidget {
   const GuidelineAnnotationCard(this.drug);
 
   final Drug drug;
 
   @override
   Widget build(BuildContext context) {
-    return RoundedCard(
-      innerPadding: const EdgeInsets.all(PharMeTheme.mediumSpace),
-      child: SingleChildScrollView(
-        child: Column(crossAxisAlignment: CrossAxisAlignment.start, children: [
-          if (drug.guidelines.isNotEmpty) ...[
-            _buildHeader(context),
-            SizedBox(height: PharMeTheme.mediumSpace),
-            _buildCard(context),
-            SizedBox(height: PharMeTheme.mediumSpace),
-            _buildSourcesSection(context),
-          ]
-          else ...[
-            _buildHeader(context),
-            SizedBox(height: PharMeTheme.smallSpace),
-            _buildCard(context),
-          ],
-        ]),
-      ),
+    return Column(
+      children: [
+        SubHeader(
+          context.l10n.drugs_page_header_guideline,
+          tooltip: _buildGuidelineTooltipText(context),
+        ),
+        SizedBox(height: PharMeTheme.smallSpace),
+        RoundedCard(
+          innerPadding: const EdgeInsets.all(PharMeTheme.mediumSpace),
+          child: SingleChildScrollView(
+            child: Column(crossAxisAlignment: CrossAxisAlignment.start, children: [
+              if (drug.guidelines.isNotEmpty) ...[
+                _buildHeader(context),
+                SizedBox(height: PharMeTheme.mediumSpace),
+                _buildCard(context),
+                SizedBox(height: PharMeTheme.mediumSpace),
+                _buildSourcesSection(context),
+              ]
+              else ...[
+                _buildHeader(context),
+                SizedBox(height: PharMeTheme.smallSpace),
+                _buildCard(context),
+              ],
+            ]),
+          ),
+        ),
+      ],
     );
   }
 
+  dynamic actualOrWarfarinContent(String drugName, BuildContext context, {
+    required dynamic actual,
+    required WarfarinContent content,
+  }) {
+    if (drugName.toLowerCase() == 'warfarin') {
+      final getWarfarinContent = warfarinProperties[content]!;
+      return getWarfarinContent(context);
+    }
+    return actual;
+  }
+
   Widget _buildCard(BuildContext context) {
-    final upperCardText = drug.userGuideline?.annotations.implication ??
-      context.l10n.drugs_page_no_guidelines_for_phenotype_implication(
-        drug.name
-      );
-    final lowerCardText = drug.userGuideline?.annotations.recommendation ??
-      context.l10n.drugs_page_no_guidelines_for_phenotype_recommendation;
+    final upperCardText = actualOrWarfarinContent(
+      drug.name,
+      context,
+      actual: drug.userGuideline?.annotations.implication ??
+        context.l10n.drugs_page_no_guidelines_for_phenotype_implication(
+          drug.name
+        ),
+      content: WarfarinContent.implication,
+    );
+    final lowerCardText = actualOrWarfarinContent(
+      drug.name,
+      context,
+      actual: drug.userGuideline?.annotations.recommendation ??
+        context.l10n.drugs_page_no_guidelines_for_phenotype_recommendation,
+      content: WarfarinContent.recommendation,
+    );
     return RoundedCard(
       key: Key('annotationCard'),
       radius: PharMeTheme.innerCardRadius,
       outerHorizontalPadding: 0,
       outerVerticalPadding: 0,
-      color: drug.warningLevel.color,
+      color: actualOrWarfarinContent(
+        drug.name,
+        context,
+        actual: drug.warningLevel.color,
+        content: WarfarinContent.color
+      ),
       child: Column(
         crossAxisAlignment: CrossAxisAlignment.start,
         children: [
           Row(children: [
             Icon(
-              drug.warningLevel.icon,
+              actualOrWarfarinContent(
+                drug.name,
+                context,
+                actual: drug.warningLevel.icon,
+                content: WarfarinContent.icon
+              ),
               color: PharMeTheme.onSurfaceText,
               size: PharMeTheme.largeSpace,
             ),
@@ -75,6 +134,27 @@ class GuidelineAnnotationCard extends StatelessWidget {
     );
   }
 
+  String _buildGuidelineTooltipText(BuildContext context) {
+    final actualTooltip = drug.userGuideline != null
+      ? context.l10n.drugs_page_tooltip_guideline(
+          drug.userGuideline!.externalData.first.source
+        )
+      : drug.userOrFirstGuideline != null
+        // Guideline for drug is present but not for genotype
+        ? context.l10n.drugs_page_tooltip_missing_guideline_for_drug_or_genotype(
+            context.l10n.drugs_page_tooltip_missing_genotype
+          )
+        : context.l10n.drugs_page_tooltip_missing_guideline_for_drug_or_genotype(
+            context.l10n.drugs_page_tooltip_missing_drug
+          );
+    return actualOrWarfarinContent(
+      drug.name,
+      context,
+      actual: actualTooltip,
+      content: WarfarinContent.tooltip,
+    );
+  }
+
   Widget _buildHeader(BuildContext context) {
     if (drug.userGuideline == null && drug.guidelines.isEmpty) {
       return Text(

app/lib/l10n/app_en.arb

@@ -201,6 +201,10 @@
     }
   },
 
+  "drugs_page_tooltip_warfarin": "CPIC guidelines provide recommendations on which drugs to use based on your DNA. However, to calculate your warfarin dose, more information is needed.",
+  "drugs_page_implication_warfarin": "More information is needed to calculate your warfarin dose.",
+  "drugs_page_recommendation_warfarin": "Consult your pharmacist or doctor for more information.",
+
   "report_content_explanation": "Here is your PGx report. Tap on a gene name for more details on your results and a list of implicated drugs.",
   "report_page_indicator_explanation": "Phenotypes followed by an {indicatorName} ({indicator}) might be influenced by drugs you are currently taking",
   "@report_page_indicator_explanation": {