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Gevaert's Lab

The Gevaert lab focuses on biomedical data fusion of complex diseases with a particular focus on oncology and cardiovascular diases. We develop novel machine learning approaches that digest multi-omics, multi-modal or multi-scale data. Previously we pioneered data fusion work using Bayesian and kernel methods studying breast and ovarian cancer. Subsequent work concerned the development of methods for multi-omics data fusion. This resulted in the development of MethylMix, to identify differentially methylated genes, and AMARETTO, a computational method to integrate DNA methylation, copy number and gene expression data to identify cancer modules. Additionally, my lab focuses on linking molecular data with cellular and tissue-level phenotypes. This led to key contributions in the field of imaging genomics/radiogenomics involving work in lung cancer and brain tumors. Our work in imaging genomics is focused on developing a framework for non-invasive personalized medicine. In summary, my lab has an interdisciplinary focus on developing novel algorithms for multi-scale biomedical data fusion.

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  1. MethylMix MethylMix Public

    Identification of differentially methylated genes in biomedical data

    R 13 11

  2. AMARETTO AMARETTO Public

    Regulatory network inference and driver gene evaluation using integrative multi-omics analysis and penalized regression

    R 16 12

Repositories

Showing 10 of 22 repositories
  • sequoia-pub Public

    SEQUOIA: Digital profiling of cancer transcriptomes with grouped vision attention

    gevaertlab/sequoia-pub’s past year of commit activity
    Python 25 MIT 3 3 0 Updated Dec 18, 2024
  • EpiMix Public
    gevaertlab/EpiMix’s past year of commit activity
    R 1 0 2 0 Updated May 1, 2024
  • .github Public
    gevaertlab/.github’s past year of commit activity
    0 0 0 0 Updated Jan 25, 2024
  • gevaertlab/Variational-Auto-Encoder’s past year of commit activity
    Jupyter Notebook 3 MIT 0 0 0 Updated Dec 15, 2023
  • GBM360 Public

    Spatial cellular architecture predicts prognosis in glioblastoma - Nature Communications

    gevaertlab/GBM360’s past year of commit activity
    Python 19 GPL-3.0 2 2 0 Updated Dec 11, 2023
  • RNA-GAN Public

    Synthetic whole-slide imaging tile generation with gene expression profiles infused deep generative models - Cell Reports Methods

    gevaertlab/RNA-GAN’s past year of commit activity
    Python 15 MIT 3 0 0 Updated Aug 31, 2023
  • gevaertlab/MultiModalBrainSurvival’s past year of commit activity
    Python 18 4 1 0 Updated Jul 20, 2023
  • EpiMix.data Public

    Supporting experiment data package for the EpiMix R package.

    gevaertlab/EpiMix.data’s past year of commit activity
    R 0 0 0 0 Updated Jun 23, 2023
  • AMARETTO Public

    Regulatory network inference and driver gene evaluation using integrative multi-omics analysis and penalized regression

    gevaertlab/AMARETTO’s past year of commit activity
    R 16 Apache-2.0 12 3 0 Updated Apr 6, 2023
  • gevaertlab/BetaVAEImputation’s past year of commit activity
    Python 12 BSD-3-Clause 4 1 1 Updated May 24, 2022

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