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Overhauled MuTect2 workflow #2

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16 changes: 4 additions & 12 deletions README.md
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## Info

- Docker used: broadinstitute/gatk:4.1.4.1
- Reference files - including PON, come from [GATK-best-practice bundle](https://console.cloud.google.com/storage/browser/gatk-best-practices/somatic-b37)
- Docker used: `gcr.io/broad-getzlab-workflows/gatk4_wolf:v6`
- Reference files - Most come from [GATK-best-practice bundle](https://console.cloud.google.com/storage/browser/gatk-best-practices/). See `wolF/reference_files.py` for details.
- Original WDL for [GATK 4.1.4.1 Best Practice](https://github.com/gatk-workflows/gatk4-somatic-snvs-indels/tree/2.7.0)
- Genome build: hg19
- Disk image:
- NAME: mutect2-wolf
- PROJECT: broad-cga-qing-gdac
- Genome build: hg38 *or* hg19

## News

A minimal implementation tested work, will add

- [x] Build a disk image for all reference files, ~~potentially as another task~~
- [ ] Cross-validate on Terra with same input
- [ ] Cost estimate
- [ ] Incorporates more optional arguments (bells and whistles)
2024-03. Reimplemented the workflow with modern wolF design patterns

## Acknowledgement

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1 change: 1 addition & 0 deletions __init__.py
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from .wolF import *
24 changes: 0 additions & 24 deletions mutect2.inputs.json

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292 changes: 0 additions & 292 deletions pipeline.py

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2 changes: 2 additions & 0 deletions wolF/__init__.py
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from .tasks import *
from .workflow import mutect2_workflow, mutect2_workflow_w_localization
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