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refactor!: split gks-common module into domain + entity (#422)
* ga4gh.core.models split into ga4gh.core.domain_models and ga4gh.core.entity_models
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"""GKS Common Library Domain Entity models | ||
**This module should not be imported directly.** | ||
Instead, users should use one of the following: | ||
* `from ga4gh.core import domain_models`, and refer to models with the | ||
abbreviated name, e.g., `domain_models.Gene` (recommended) | ||
* `import ga4gh.core`, and refer to models using the fully-qualified | ||
module name, e.g., `ga4gh.core.domain_models.Gene` | ||
""" | ||
from typing import Literal, Union, List | ||
from enum import Enum | ||
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from pydantic import Field, RootModel | ||
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from ga4gh.core.entity_models import _DomainEntity | ||
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class CommonDomainType(str, Enum): | ||
"""Define GKS Common Domain Entity types""" | ||
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PHENOTYPE = "Phenotype" | ||
DISEASE = "Disease" | ||
TRAIT_SET = "TraitSet" | ||
TR_ACTION = "TherapeuticAction" | ||
TR_AGENT = "TherapeuticAgent" | ||
TR_SUB = "TherapeuticSubstituteGroup" | ||
TR_COMB = "CombinationTherapy" | ||
GENE = "Gene" | ||
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class Phenotype(_DomainEntity): | ||
"""An observable characteristic or trait of an organism.""" | ||
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type: Literal[CommonDomainType.PHENOTYPE] = Field( | ||
CommonDomainType.PHENOTYPE, | ||
description=f'MUST be "{CommonDomainType.PHENOTYPE.value}".' | ||
) | ||
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class Disease(_DomainEntity): | ||
"""A particular abnormal condition that negatively affects the structure or function | ||
of all or part of an organism and is not immediately due to any external injury. | ||
""" | ||
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type: Literal[CommonDomainType.DISEASE] = Field( | ||
CommonDomainType.DISEASE, | ||
description=f'MUST be "{CommonDomainType.DISEASE.value}".' | ||
) | ||
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class TraitSet(_DomainEntity): | ||
"""A set of phenotype and/or disease concepts that together constitute a condition.""" | ||
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type: Literal[CommonDomainType.TRAIT_SET] = Field( | ||
CommonDomainType.TRAIT_SET, | ||
description=f'MUST be "{CommonDomainType.TRAIT_SET.value}".' | ||
) | ||
traits: List[Union[Disease, Phenotype]] = Field( | ||
..., | ||
min_length=2 | ||
) | ||
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class Condition(RootModel): | ||
"""A disease or other medical disorder.""" | ||
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root: Union[TraitSet, Disease, Phenotype] = Field( | ||
..., | ||
json_schema_extra={'description': 'A disease or other medical disorder.'}, | ||
discriminator='type', | ||
) | ||
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class TherapeuticAction(_DomainEntity): | ||
"""A therapeutic action taken that is intended to alter or stop a pathologic process.""" | ||
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type: Literal[CommonDomainType.TR_ACTION] = Field( | ||
CommonDomainType.TR_ACTION, | ||
description=f'MUST be "{CommonDomainType.TR_ACTION.value}".' | ||
) | ||
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class TherapeuticAgent(_DomainEntity): | ||
"""An administered therapeutic agent that is intended to alter or stop a pathologic process.""" | ||
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type: Literal[CommonDomainType.TR_AGENT] = Field( | ||
CommonDomainType.TR_AGENT, | ||
description=f'MUST be "{CommonDomainType.TR_AGENT.value}".' | ||
) | ||
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class TherapeuticSubstituteGroup(_DomainEntity): | ||
"""A group of therapeutic procedures that may be treated as substitutes for one another.""" | ||
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type: Literal[CommonDomainType.TR_SUB] = Field( | ||
CommonDomainType.TR_SUB, | ||
description=f'MUST be "{CommonDomainType.TR_SUB.value}".' | ||
) | ||
substitutes: List[Union[TherapeuticAction, TherapeuticAgent]] = Field( | ||
..., | ||
description='The individual therapeutic procedures that may be treated as substitutes.', | ||
min_length=2 | ||
) | ||
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class CombinationTherapy(_DomainEntity): | ||
"""A therapeutic procedure that involves multiple different therapeutic procedures | ||
performed in combination. | ||
""" | ||
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type: Literal[CommonDomainType.TR_COMB] = Field( | ||
CommonDomainType.TR_COMB, | ||
description=f'MUST be "{CommonDomainType.TR_COMB.value}".' | ||
) | ||
components: List[Union[TherapeuticSubstituteGroup, TherapeuticAction, TherapeuticAgent]] = Field( | ||
..., | ||
description='The individual therapeutic procedure components that constitute the combination therapy.', | ||
min_length=2 | ||
) | ||
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class TherapeuticProcedure(RootModel): | ||
"""An action or administration of therapeutic agents to produce an effect that is | ||
intended to alter or stop a pathologic process. | ||
""" | ||
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root: Union[CombinationTherapy, TherapeuticSubstituteGroup, TherapeuticAction, TherapeuticAgent] = Field( | ||
..., | ||
json_schema_extra={'description': 'An action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process.'}, | ||
discriminator='type', | ||
) | ||
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class Gene(_DomainEntity): | ||
"""A basic physical and functional unit of heredity.""" | ||
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type: Literal[CommonDomainType.GENE] = Field( | ||
CommonDomainType.GENE, | ||
description=f'MUST be "{CommonDomainType.GENE.value}".' | ||
) |
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