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Statial

Overview

Statial is a suite of functions for identifying changes in cell state. The functionality provided by Statial provides robust quantification of cell type localisation which are invariant to changes in tissue structure. In addition to this Statial uncovers changes in marker expression associated with varying levels of localisation. These features can be used to explore how the structure and function of different cell types may be altered by the agents they are surrounded with.

Installation

Installing the package from Bioconductor.

if (!requireNamespace("BiocManager", quietly = TRUE)) {
    install.packages("BiocManager")
}

BiocManager::install("Statial")

Otherwise, install the development version from GitHub.

# Install the development version from GitHub:
# install.packages("devtools")
devtools::install_github("SydneyBioX/Statial")
library(Statial)

Submitting an issue or feature request

Statial is still under active development. We would greatly appreciate any and all feedback related to the package.

  • R package related issues should be raised here.
  • For general questions and feedback, please contact us directly via [email protected].

Authors

Kontextual pre-print

Farhan Ameen, Nicholas Robertson, David M. Lin, Shila Ghazanfar, Ellis Patrick bioRxiv 2024.09.03.611109; doi: https://doi.org/10.1101/2024.09.03.611109