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I believe this text mining result was false. The paper looked at a rat model with higher and lower glucose levels but it doesn't look like they actually did transcriptomics for this portion of their experiment. Their cell model results are here https://ncbi.nlm.nih.gov/geo/geo2r/?acc=GSE169649 and even if you accept the jump of O-GlyNAc being a proxy of glucose, the numbers don't show any increase in KMT2A that I could find. The "Title" sections had conflicting information from the "Treatment" sections but analyzing based on Treatment (except for day 12) looked like it had more sensical PCA plots. Even then, I analysed D0, D12, D30, and D70 and never found an instance of KMT2A being elevated.
#980
Type: Other Comment
URL: null
ARS PK: 2bf9562b-3547-4a77-aec6-5210cca007f8
Steps to reproduce:
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