This repository contains research works related to artificial intelligence application in the study of human diseases, focusing on Alzheimer's disease. Works from both life science and computer science communities are collected in addition to remarkable datasets in this area. The repo is updated in real time.
📄: review, 🔓: open data
- IF >6, works on AI application for human disease are collected, focusing on (but not limited to) AD. To be updated.
Articles related to ML4ND
- Data-driven modelling of neurodegenerative disease progression: thinking outside the black box [article] 📄
Articles related to ML4gene
- Optimal trade-off control in machine learning–based library design, with application to adeno-associated virus (AAV) for gene therapy [article] 🔖
Articles related to AI4AD
- Artificial Intelligence and Technology Collaboratories: Innovating aging research and Alzheimer's care [article]
Articles related to AI4AD
- Plasma proteomic profiles predict individual future health risk [article]🔖
Articles related to AI4multi-omics
- SCENIC+: single-cell multiomic inference of enhancers and gene regulatory networks [article]]
- scGPT: toward building a foundation model for single-cell multi-omics using generative AI [article]
Articles related to AD and potential for AI application
- Plasma proteomic profiles predict future dementia in healthy adults [article] 🔖
Articles related to ML4dementia
- The use of neuroimaging techniques in the early and differential diagnosis of dementia [articel] {neuroimaging}
Articles related to AI4AD
- Alzheimer’s dementia early diagnosis, characterization, prognosis and treatment decision via a software-as-medical device with an artificial intelligent agent [article] {MRI, neuropsychological tests}
- Artificial neural network visualization methods reveal diagnostically relevant brain regions to detect Alzheimer’s disease: The first step towards comprehensive artificial intelligence [article] {CNN, visualization}
- Artificial intelligence for dementia prevention [article] 📄
- Artificial intelligence for biomarker discovery in Alzheimer's disease and dementia [article] 📄
- Artificial intelligence for diagnostic and prognostic neuroimaging in dementia: A systematic review [article] 📄
- Artificial intelligence for dementia research methods optimization [article] 📄
- Artificial intelligence for dementia genetics and omics [article] 📄
- Artificial intelligence for dementia—Applied models and digital health [article] 📄
- Artificial intelligence for dementia drug discovery and trials optimization [article] 📄
- Artificial intelligence for neurodegenerative experimental models [article] 📄
- Using blood transcriptome analysis for Alzheimer’s disease diagnosis and patient stratification [article] {unsupervised clustering analysis, genes, gene modules, cell types} 🔖
Articles related to AI4AD
- A robust and interpretable machine learning approach using multimodal biological data to predict future pathological tau accumulation [article] {multimodal}
- A computational model of neurodegeneration in Alzheimer’s disease [article]
Articles related to AD and potential for AI application
- CSF proteome profiling across the Alzheimer’s disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels [article] 🔖
- A high-generalizability machine learning framework for predicting the progression of Alzheimer’s disease using limited data [article] {hybrid CNN, limited data, brain segments image} 🔓
Just an interesting one
- Quantitative evaluation of explainable graph neural networks for molecular property prediction [article] 🔓
Articles related to AI4AD
- Unified AI framework to uncover deep interrelationships between gene expression and Alzheimer’s disease neuropathologies [article] 🔖 {Multi-task Deep learning}
- A machine learning approach to brain epigenetic analysis reveals kinases associated with Alzheimer’s disease [article]
- Machine learning identifies candidates for drug repurposing in Alzheimer’s disease [article]
- A deep learning framework identifies dimensional representations of Alzheimer’s Disease from brain structure [article] {disease subtypes using clustering in GAN, neuroimaging} 🔖
Articles related to AI4AD
- Multimodal deep learning for Alzheimer’s disease dementia assessment [article] {DL, CV}
Articles related to AI4AD
- Applications of machine learning to diagnosis and treatment of neurodegenerative diseases [article] 📄
Articles related to ML4AD
- Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow [article] {unsupervised learning, molecular structures, pharmacophore fingerprinting, conformer fingerprinting}
Articles related to AI4AD
- Interpretable classification of Alzheimer’s disease pathologies with a convolutional neural network pipeline [article]
Articles related to AI4AD
- A deep learning model for early prediction of Alzheimer's disease dementia based on hippocampal magnetic resonance imaging data [article]
Articles related to ML4AD
- Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference [article]
- To be updated.
- Comparison Between Explainable AI Algorithms for Alzheimer’s Disease Prediction Using EfficientNet Models (ICBI'23) [paper]
- Explainable Artificial Intelligence in Alzheimer’s Disease Classification: A Systematic Review (Cognitive Computation'23interdisciplinary journal) [article] 📄
- Alzheimer's Disease Analysis using Explainable Artificial Intelligence (XAI) (ICSCDS'22) [paper]
- Exploring Alzheimer's Disease Prediction with XAI in various Neural Network Models (TENCON'21) [paper]
- Alzheimer’s Patient Analysis Using Image and Gene Expression Data and Explainable-AI to Present Associated Genes (Transactions on Instrumentation and Measurement'21) [paper]
- UK Biobank : plasma samples from more than 50,000 UK Biobank participants with phenotypic and genotypic data, stratifying on British or Irish, African and South Asian ancestries.
Some updated related articles: [Science Translational Medicine'24] [BJC'22] [Nature'18]
- Synapse: (currently down)