We created this css-only memory game as an experiment at one of our company days' hackathons. You can try it out here: https://edmdesigner.github.io/moorhuhn-clone-in-email-poc/
Supported email clients: https://www.caniemail.com/search/?s=checked
You can achieve support for Gmail if you send it as an AMP email. (You will have to make some changes, for example replace the img tags with amp-img.)
We are planning to introduce similar interactive functionalities in our APP and SDK.
Flying bird source: https://ma9ici4n.itch.io/pixel-art-bird-16x16
Background source: https://pinterest.com/pin/365987907196275478/