First release of Annotation Comparison Explorer (ACE)
ACE is A versatile tool for comparing annotations across cell types, metadata, and taxonomies! It enables researchers to:
- Compare cell types across studies: Identify consistent changes in cell types related to diseases like Alzheimer's disease.
- Convert cell type classifications: Translate cell types between different Allen Institute-hosted classifications (or 'taxonomies').
- Evaluate clustering results: Compare user-generated clusters with established cell type classifications.
- Explore spatial and functional relationships: Analyze cell type distribution in brain regions and correlate with other cell properties.
- Assess data quality: Evaluate cell type data based on quality control metrics.
- Visualize cell type abundance: Compare cell type abundance across different conditions or groups.
- Perform general data exploration: Analyze various types of data beyond cell types using visualization tools.
This is a largely stable version, with a few known issues. Future versions will:
- Add new comparison tables for exploration
- Fix bookmarking to allow one to revisit any state of the app
- Add video tutorials to complement the existing User Guide
- Allow users to upload a file to the web tool directly
Please reach out via the "Feedback" button in the tool or by submitting a GitHub Issue if you have any comments about ACE.