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Adjust to new somatic/germline structure #198

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holtgrewe opened this issue Apr 29, 2024 · 1 comment · Fixed by #201
Closed

Adjust to new somatic/germline structure #198

holtgrewe opened this issue Apr 29, 2024 · 1 comment · Fixed by #201
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@holtgrewe
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holtgrewe commented Apr 29, 2024

Describe the bug
ClinVar has updated their data structures with a separation of somatic and germline variants. Without adding support for this, we cannot parse current ClinVar XML.

To Reproduce
N/A

Expected behavior
We need to add parsing support for both germline and somatic variants. We will need to write out both th <e old assessment information and add support for the new one.

Additional context

@holtgrewe
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It is probably most promising to first generate a protobuf file from the ClinVar XSD. The one existing converter appears to be schema2proto. However, it has problems:

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