diff --git a/conda/env/lock/pcgr-linux-64.lock b/conda/env/lock/pcgr-linux-64.lock
index db257684..76ed5960 100644
--- a/conda/env/lock/pcgr-linux-64.lock
+++ b/conda/env/lock/pcgr-linux-64.lock
@@ -1,6 +1,6 @@
 # Generated by conda-lock.
 # platform: linux-64
-# input_hash: 05281bc3c331be5d12bb1c83433c007c3bf88147c2376541ee51826efe9b7180
+# input_hash: e0bb967a48030190e9194ebda85d220d2aa530d652f188c1f0b4f31f99074c41
 @EXPLICIT
 https://conda.anaconda.org/conda-forge/linux-64/_libgcc_mutex-0.1-conda_forge.tar.bz2#d7c89558ba9fa0495403155b64376d81
 https://conda.anaconda.org/bioconda/linux-64/blast-legacy-2.2.26-h9ee0642_3.tar.bz2#b7fe67ef984501e8089a142f1f58ab2f
@@ -15,8 +15,8 @@ https://conda.anaconda.org/conda-forge/linux-64/libgomp-14.1.0-h77fa898_0.conda#
 https://conda.anaconda.org/conda-forge/linux-64/_openmp_mutex-4.5-2_gnu.tar.bz2#73aaf86a425cc6e73fcf236a5a46396d
 https://conda.anaconda.org/conda-forge/linux-64/libgcc-ng-14.1.0-h77fa898_0.conda#ca0fad6a41ddaef54a153b78eccb5037
 https://conda.anaconda.org/conda-forge/linux-64/argtable2-2.13-hd590300_1004.conda#d7d089e975b1213c2a0f94e592b7b422
-https://conda.anaconda.org/conda-forge/linux-64/bzip2-1.0.8-hd590300_5.conda#69b8b6202a07720f448be700e300ccf4
-https://conda.anaconda.org/conda-forge/linux-64/c-ares-1.28.1-hd590300_0.conda#dcde58ff9a1f30b0037a2315d1846d1f
+https://conda.anaconda.org/conda-forge/linux-64/bzip2-1.0.8-h4bc722e_7.conda#62ee74e96c5ebb0af99386de58cf9553
+https://conda.anaconda.org/conda-forge/linux-64/c-ares-1.32.2-h4bc722e_0.conda#8024af1ee7078e37fa3101c0a0296af2
 https://conda.anaconda.org/conda-forge/linux-64/gettext-tools-0.22.5-h59595ed_2.conda#985f2f453fb72408d6b6f1be0f324033
 https://conda.anaconda.org/conda-forge/linux-64/keyutils-1.6.1-h166bdaf_0.tar.bz2#30186d27e2c9fa62b45fb1476b7200e3
 https://conda.anaconda.org/conda-forge/linux-64/libdeflate-1.20-hd590300_0.conda#8e88f9389f1165d7c0936fe40d9a9a79
@@ -39,13 +39,13 @@ https://conda.anaconda.org/bioconda/linux-64/poa-2.0-h031d066_5.tar.bz2#7f92f2dd
 https://conda.anaconda.org/conda-forge/linux-64/unzip-6.0-h7f98852_3.tar.bz2#7cb7109505433a5abbf68bb34b31edac
 https://conda.anaconda.org/conda-forge/linux-64/xz-5.2.6-h166bdaf_0.tar.bz2#2161070d867d1b1204ea749c8eec4ef0
 https://conda.anaconda.org/conda-forge/linux-64/yaml-0.2.5-h7f98852_2.tar.bz2#4cb3ad778ec2d5a7acbdf254eb1c42ae
-https://conda.anaconda.org/bioconda/linux-64/bedtools-2.31.1-hf5e1c6e_1.tar.bz2#2066287e826a2ff469fa0b62b24b6059
+https://conda.anaconda.org/bioconda/linux-64/bedtools-2.31.1-hf5e1c6e_2.tar.bz2#55aacbd977c83d6d4849c91310ef48c5
 https://conda.anaconda.org/bioconda/linux-64/clustalo-1.2.4-hdbdd923_8.tar.bz2#9baa8c81d5ca18a5336fe748bfa8e7a9
 https://conda.anaconda.org/bioconda/linux-64/clustalw-2.1-h4ac6f70_10.tar.bz2#e7756d46d67ea32f90b684f6770f290d
 https://conda.anaconda.org/conda-forge/linux-64/expat-2.6.2-h59595ed_0.conda#53fb86322bdb89496d7579fe3f02fd61
 https://conda.anaconda.org/conda-forge/linux-64/gmp-6.3.0-hac33072_2.conda#c94a5994ef49749880a8139cf9afcbe1
 https://conda.anaconda.org/conda-forge/linux-64/icu-73.2-h59595ed_0.conda#cc47e1facc155f91abd89b11e48e72ff
-https://conda.anaconda.org/conda-forge/linux-64/libabseil-20240116.2-cxx17_h59595ed_0.conda#682bdbe046a68f749769b492f3625c5c
+https://conda.anaconda.org/conda-forge/linux-64/libabseil-20240116.2-cxx17_he02047a_1.conda#c48fc56ec03229f294176923c3265c05
 https://conda.anaconda.org/conda-forge/linux-64/libasprintf-0.22.5-h661eb56_2.conda#dd197c968bf9760bba0031888d431ede
 https://conda.anaconda.org/conda-forge/linux-64/libdb-6.2.32-h9c3ff4c_0.tar.bz2#3f3258d8f841fbac63b36b75bdac1afd
 https://conda.anaconda.org/conda-forge/linux-64/libedit-3.1.20191231-he28a2e2_2.tar.bz2#4d331e44109e3f0e19b4cb8f9b82f3e1
@@ -59,7 +59,7 @@ https://conda.anaconda.org/conda-forge/linux-64/lz4-c-1.9.4-hcb278e6_0.conda#318
 https://conda.anaconda.org/bioconda/linux-64/muscle-5.1-h4ac6f70_3.tar.bz2#aea487cbcbed07625e0963472c4ac568
 https://conda.anaconda.org/conda-forge/linux-64/mysql-common-8.3.0-hf1915f5_4.conda#784a4df6676c581ca624fbe460703a6d
 https://conda.anaconda.org/conda-forge/linux-64/mysql-connector-c-6.1.11-h659d440_1008.conda#149e0b89cbbe09397f1147cb3736bcbe
-https://conda.anaconda.org/bioconda/linux-64/ncbi-vdb-3.1.1-h4ac6f70_0.tar.bz2#4cbc542ee7db0710bdf07a4e55f5daaf
+https://conda.anaconda.org/bioconda/linux-64/ncbi-vdb-3.1.1-h4ac6f70_1.tar.bz2#05705db906896430d0d963de7a3c1698
 https://conda.anaconda.org/conda-forge/linux-64/pcre-8.45-h9c3ff4c_0.tar.bz2#c05d1820a6d34ff07aaaab7a9b7eddaa
 https://conda.anaconda.org/conda-forge/linux-64/perl-5.32.1-7_hd590300_perl5.conda#f2cfec9406850991f4e3d960cc9e3321
 https://conda.anaconda.org/conda-forge/linux-64/readline-8.2-h8228510_1.conda#47d31b792659ce70f470b5c82fdfb7a4
@@ -68,7 +68,7 @@ https://conda.anaconda.org/conda-forge/linux-64/zlib-1.2.13-h4ab18f5_6.conda#559
 https://conda.anaconda.org/conda-forge/linux-64/zstd-1.5.6-ha6fb4c9_0.conda#4d056880988120e29d75bfff282e0f45
 https://conda.anaconda.org/conda-forge/linux-64/krb5-1.21.3-h659f571_0.conda#3f43953b7d3fb3aaa1d0d0723d91e368
 https://conda.anaconda.org/conda-forge/linux-64/libasprintf-devel-0.22.5-h661eb56_2.conda#02e41ab5834dcdcc8590cf29d9526f50
-https://conda.anaconda.org/conda-forge/linux-64/libopenblas-0.3.27-pthreads_h413a1c8_0.conda#a356024784da6dfd4683dc5ecf45b155
+https://conda.anaconda.org/conda-forge/linux-64/libopenblas-0.3.27-pthreads_hac2b453_1.conda#ae05ece66d3924ac3d48b4aa3fa96cec
 https://conda.anaconda.org/conda-forge/linux-64/libprotobuf-4.25.3-h08a7969_0.conda#6945825cebd2aeb16af4c69d97c32c13
 https://conda.anaconda.org/conda-forge/linux-64/mpfr-4.2.1-h9458935_1.conda#8083b20f566639c22f78bcd6ca35b276
 https://conda.anaconda.org/conda-forge/linux-64/mysql-client-8.3.0-h545f5f4_4.conda#0570644b7f6a2f104242653405a56d09
@@ -148,14 +148,14 @@ https://conda.anaconda.org/bioconda/noarch/perl-types-serialiser-1.01-pl5321hdfd
 https://conda.anaconda.org/conda-forge/noarch/python-tzdata-2024.1-pyhd8ed1ab_0.conda#98206ea9954216ee7540f0c773f2104d
 https://conda.anaconda.org/conda-forge/noarch/pytz-2024.1-pyhd8ed1ab_0.conda#3eeeeb9e4827ace8c0c1419c85d590ad
 https://conda.anaconda.org/conda-forge/linux-64/pyyaml-6.0.1-py312h98912ed_1.conda#e3fd78d8d490af1d84763b9fe3f2e552
-https://conda.anaconda.org/conda-forge/noarch/setuptools-70.1.1-pyhd8ed1ab_0.conda#985e9e86e1b0fc75a74a9bfab9309ef7
+https://conda.anaconda.org/conda-forge/noarch/setuptools-70.3.0-pyhd8ed1ab_0.conda#693bb57e8f92120caa956898065f3627
 https://conda.anaconda.org/conda-forge/noarch/six-1.16.0-pyh6c4a22f_0.tar.bz2#e5f25f8dbc060e9a8d912e432202afc2
 https://conda.anaconda.org/bioconda/linux-64/viennarna-2.6.4-py312pl5321hc60241a_2.tar.bz2#75cf75a55e6d974779303172ef49f546
 https://conda.anaconda.org/conda-forge/noarch/wheel-0.43.0-pyhd8ed1ab_1.conda#0b5293a157c2b5cd513dd1b03d8d3aae
 https://conda.anaconda.org/conda-forge/noarch/coloredlogs-15.0.1-pyhd8ed1ab_3.tar.bz2#7b4fc18b7f66382257c45424eaf81935
 https://conda.anaconda.org/conda-forge/linux-64/curl-8.8.0-he654da7_1.conda#78678b2ddfd9bd7c7861b8d2e3b7473b
 https://conda.anaconda.org/conda-forge/linux-64/gawk-5.3.0-ha916aea_0.conda#66ef869337c8061f6a96b0348d138a62
-https://conda.anaconda.org/bioconda/linux-64/htslib-1.20-h5efdd21_1.tar.bz2#451deefa67e250cf3268a484d9734465
+https://conda.anaconda.org/bioconda/linux-64/htslib-1.20-h5efdd21_2.tar.bz2#f0923cdb85b44dc77bdead8018645ea9
 https://conda.anaconda.org/conda-forge/linux-64/libcblas-3.9.0-22_linux64_openblas.conda#4b31699e0ec5de64d5896e580389c9a1
 https://conda.anaconda.org/conda-forge/linux-64/libidn2-2.3.7-hd590300_0.conda#2b7b0d827c6447cc1d85dc06d5b5de46
 https://conda.anaconda.org/conda-forge/linux-64/liblapack-3.9.0-22_linux64_openblas.conda#b083767b6c877e24ee597d93b87ab838
@@ -172,23 +172,23 @@ https://conda.anaconda.org/bioconda/linux-64/perl-pathtools-3.75-pl5321hec16e2b_
 https://conda.anaconda.org/bioconda/noarch/perl-test-differences-0.69-pl5321hdfd78af_0.tar.bz2#1f7a9aa718798b8f9544d0a80dea3673
 https://conda.anaconda.org/bioconda/noarch/perl-time-local-1.35-pl5321hdfd78af_0.tar.bz2#e813d43b775e17589b5dd9cd99b3e8b6
 https://conda.anaconda.org/conda-forge/noarch/pip-24.0-pyhd8ed1ab_0.conda#f586ac1e56c8638b64f9c8122a7b8a67
-https://conda.anaconda.org/bioconda/linux-64/pysam-0.22.1-py312hcfdcdd7_1.tar.bz2#03863e6584f040bd17e5c5a519bdcb18
+https://conda.anaconda.org/bioconda/linux-64/pysam-0.22.1-py312hcfdcdd7_2.tar.bz2#33baeca8a223d34355fd37bc9e14a128
 https://conda.anaconda.org/conda-forge/noarch/python-dateutil-2.9.0-pyhd8ed1ab_0.conda#2cf4264fffb9e6eff6031c5b6884d61c
 https://conda.anaconda.org/conda-forge/linux-64/gsl-2.7-he838d99_0.tar.bz2#fec079ba39c9cca093bf4c00001825de
 https://conda.anaconda.org/bioconda/linux-64/mafft-7.525-h031d066_1.tar.bz2#cc14d0dc05b87e030ee1cc168e33cedf
 https://conda.anaconda.org/conda-forge/linux-64/mysql-8.3.0-h27aab58_4.conda#876fca579d3aa248729bd7a2d38ae428
-https://conda.anaconda.org/conda-forge/linux-64/numpy-1.26.4-py312heda63a1_0.conda#d8285bea2a350f63fab23bf460221f3f
+https://conda.anaconda.org/conda-forge/linux-64/numpy-2.0.0-py312h22e1c76_0.conda#7956c7d65f87aecaba720af6088e72c3
 https://conda.anaconda.org/bioconda/noarch/perl-archive-tar-2.40-pl5321hdfd78af_0.tar.bz2#ef5f007762b5ad9425694104d7db4463
 https://conda.anaconda.org/bioconda/noarch/perl-bioperl-run-1.007003-pl5321hdfd78af_0.tar.bz2#5b7b092efda407c9af1981426d83f3f5
 https://conda.anaconda.org/bioconda/noarch/perl-business-isbn-3.007-pl5321hdfd78af_0.tar.bz2#3cdaa3f73497365e08346443d81dac81
 https://conda.anaconda.org/bioconda/noarch/perl-http-date-6.06-pl5321hdfd78af_0.tar.bz2#dbf1658443c214ea04fce36312d7efe3
 https://conda.anaconda.org/bioconda/noarch/perl-json-4.10-pl5321hdfd78af_0.tar.bz2#05467eeb1e57206d8dddf31c3128cd00
 https://conda.anaconda.org/bioconda/noarch/perl-test-most-0.38-pl5321hdfd78af_0.tar.bz2#af484f1f44bf33bb0a6ab33e109ab8cb
-https://conda.anaconda.org/bioconda/linux-64/samtools-1.20-h50ea8bc_0.tar.bz2#7b3b1d0feea64e7e211ae24e7cd126d8
+https://conda.anaconda.org/bioconda/linux-64/samtools-1.20-h50ea8bc_1.tar.bz2#1a4c52f8079fea1b18b3e4bd329bab3a
 https://conda.anaconda.org/bioconda/linux-64/vt-2015.11.10-h5ef6573_4.tar.bz2#540c2f97ff7f75a2f83c3a642c50bd37
 https://conda.anaconda.org/conda-forge/linux-64/wget-1.21.4-hda4d442_0.conda#361e96b664eac64a33c20dfd11affbff
-https://conda.anaconda.org/bioconda/linux-64/bcftools-1.20-h8b25389_0.tar.bz2#227ba3d820ac2f171b2ee20eb780cbac
-https://conda.anaconda.org/bioconda/linux-64/cyvcf2-0.31.0-py312h16c6d63_1.tar.bz2#1abd6c5c205266b5384697803576d282
+https://conda.anaconda.org/bioconda/linux-64/bcftools-1.20-h8b25389_1.tar.bz2#7dea9d0b49ecf4a553472add3d297729
+https://conda.anaconda.org/bioconda/linux-64/cyvcf2-0.31.1-py312h68a07e8_0.tar.bz2#e68bad1a1bc2a5b926b1a61c8347497b
 https://conda.anaconda.org/bioconda/linux-64/entrez-direct-22.1-he881be0_0.tar.bz2#57b4957374cfeb937f02aa75670b02fa
 https://conda.anaconda.org/conda-forge/linux-64/pandas-2.2.2-py312h1d6d2e6_1.conda#ae00b61f3000d2284d1f2584d4dfafa8
 https://conda.anaconda.org/bioconda/noarch/perl-bio-asn1-entrezgene-1.73-pl5321hdfd78af_3.tar.bz2#1fa1e8f39aad93a6dc5a07b5bbb0d648
@@ -201,7 +201,7 @@ https://conda.anaconda.org/bioconda/linux-64/pybedtools-0.10.0-py312ha1f7cf2_1.t
 https://conda.anaconda.org/conda-forge/linux-64/scipy-1.14.0-py312hc2bc53b_1.conda#eae80145f63aa04a02dda456d4883b46
 https://conda.anaconda.org/bioconda/noarch/vcf2maf-umccr-1.6.21.20230511-hdfd78af_0.tar.bz2#ec3a03df0bce17c35b2a2d1436c718ea
 https://conda.anaconda.org/bioconda/linux-64/blast-2.15.0-pl5321h6f7f691_1.tar.bz2#f7e6a87317b5d00469d39a2d1ef2698f
-https://conda.anaconda.org/pcgr/noarch/pcgr-2.0.1-py_0.tar.bz2#eec67f68553213c0227d7d9fc3b9dcdb
+https://conda.anaconda.org/pcgr/noarch/pcgr-2.0.2-py_0.tar.bz2#5bc257e15d72598686e5a627889a2d2d
 https://conda.anaconda.org/bioconda/noarch/perl-http-message-6.36-pl5321hdfd78af_0.tar.bz2#a213d1308ffa8e0789996ae6ecda98ae
 https://conda.anaconda.org/bioconda/noarch/perl-net-http-6.22-pl5321hdfd78af_0.tar.bz2#f3b44f2b9932c3def346e6ad9aabe43d
 https://conda.anaconda.org/bioconda/noarch/perl-www-robotrules-6.02-pl5321hdfd78af_4.tar.bz2#8305f4ed6306b1125a8c8caf2f05aec8
diff --git a/conda/env/lock/pcgr-osx-64.lock b/conda/env/lock/pcgr-osx-64.lock
index ef0752d7..a203417f 100644
--- a/conda/env/lock/pcgr-osx-64.lock
+++ b/conda/env/lock/pcgr-osx-64.lock
@@ -1,10 +1,8 @@
 # Generated by conda-lock.
 # platform: osx-64
-# input_hash: 4066030da1213363917d57a6ac2a7fe6b72e4638610a31adb70476c89bd137b1
+# input_hash: 9ace53fcafd294f50dccff55d42d6f90d7301818e3f8ef8a84913b776eac31bb
 @EXPLICIT
 https://conda.anaconda.org/conda-forge/osx-64/argtable2-2.13-h10d778d_1004.conda#7ebcbc431363dfbf9ae25e6a7205d414
-https://conda.anaconda.org/conda-forge/osx-64/bzip2-1.0.8-h10d778d_5.conda#6097a6ca9ada32699b5fc4312dd6ef18
-https://conda.anaconda.org/conda-forge/osx-64/c-ares-1.28.1-h10d778d_0.conda#d5eb7992227254c0e9a0ce71151f0079
 https://conda.anaconda.org/conda-forge/osx-64/ca-certificates-2024.7.4-h8857fd0_0.conda#7df874a4b05b2d2b82826190170eaa0f
 https://conda.anaconda.org/conda-forge/osx-64/libasprintf-0.22.5-h5ff76d1_2.conda#ad803793d7168331f1395685cbdae212
 https://conda.anaconda.org/conda-forge/osx-64/libdeflate-1.20-h49d49c5_0.conda#d46104f6a896a0bc6a1d37b88b2edf5c
@@ -24,9 +22,11 @@ https://conda.anaconda.org/conda-forge/osx-64/unzip-6.0-h0d85af4_3.tar.bz2#e4bc5
 https://conda.anaconda.org/bioconda/osx-64/vcfanno-0.3.5-h527b516_1.tar.bz2#d0621866e457d007f02b28d781b50395
 https://conda.anaconda.org/conda-forge/osx-64/xz-5.2.6-h775f41a_0.tar.bz2#a72f9d4ea13d55d745ff1ed594747f10
 https://conda.anaconda.org/conda-forge/osx-64/yaml-0.2.5-h0d85af4_2.tar.bz2#d7e08fcf8259d742156188e8762b4d20
+https://conda.anaconda.org/conda-forge/osx-64/bzip2-1.0.8-hfdf4475_7.conda#7ed4301d437b59045be7e051a0308211
+https://conda.anaconda.org/conda-forge/osx-64/c-ares-1.32.2-h51dda26_0.conda#be4a9b58fcf1374aeb79e873c1166e19
 https://conda.anaconda.org/conda-forge/osx-64/expat-2.6.2-h73e2aa4_0.conda#dc0882915da2ec74696ad87aa2350f27
 https://conda.anaconda.org/conda-forge/osx-64/libasprintf-devel-0.22.5-h5ff76d1_2.conda#c7182eda3bc727384e2f98f4d680fa7d
-https://conda.anaconda.org/conda-forge/osx-64/libcxx-17.0.6-heb59cac_3.conda#ef15f182e353155497e13726b915bfc4
+https://conda.anaconda.org/conda-forge/osx-64/libcxx-18.1.8-hef8daea_0.conda#4101cde4241c92aeac310d65e6791579
 https://conda.anaconda.org/conda-forge/osx-64/libedit-3.1.20191231-h0678c8f_2.tar.bz2#6016a8a1d0e63cac3de2c352cd40208b
 https://conda.anaconda.org/conda-forge/osx-64/libintl-0.22.5-h5ff76d1_2.conda#3fb6774cb8cdbb93a6013b67bcf9716d
 https://conda.anaconda.org/conda-forge/osx-64/libzlib-1.2.13-h87427d6_6.conda#c0ef3c38a80c02ae1d86588c055184fc
@@ -74,7 +74,7 @@ https://conda.anaconda.org/bioconda/osx-64/perl-url-encode-0.03-pl5321h527b516_0
 https://conda.anaconda.org/bioconda/noarch/perl-xml-regexp-0.04-pl5321hdfd78af_3.tar.bz2#8a5a1bd078a08890084e93cd5eff3fa7
 https://conda.anaconda.org/bioconda/noarch/perl-xml-xpathengine-0.14-pl5321hdfd78af_3.tar.bz2#4af616066d02762108e88cf5413d3ded
 https://conda.anaconda.org/conda-forge/osx-64/readline-8.2-h9e318b2_1.conda#f17f77f2acf4d344734bda76829ce14e
-https://conda.anaconda.org/bioconda/osx-64/bedtools-2.31.1-h6372da2_1.tar.bz2#ab3a6b46413bb7a7baaaf5589aec0caf
+https://conda.anaconda.org/bioconda/osx-64/bedtools-2.31.1-hdd9cfa2_2.tar.bz2#1f66f8ceac0e134b67f297caa63c0450
 https://conda.anaconda.org/bioconda/osx-64/clustalo-1.2.4-h7133b54_8.tar.bz2#cb5f47a0f971ecca37aea71f0b9acc5e
 https://conda.anaconda.org/bioconda/osx-64/clustalw-2.1-h85dcccf_10.tar.bz2#a3d76c53d3685e26245bcbf0ee89b3f5
 https://conda.anaconda.org/conda-forge/osx-64/gettext-tools-0.22.5-h5ff76d1_2.conda#37e1cb0efeff4d4623a6357e37e0105d
@@ -95,7 +95,7 @@ https://conda.anaconda.org/conda-forge/osx-64/lz4-c-1.9.4-hf0c8a7f_0.conda#aa04f
 https://conda.anaconda.org/bioconda/osx-64/muscle-5.1-h7d747a2_3.tar.bz2#81b3ad80ed932a9307d61bee17c95f38
 https://conda.anaconda.org/conda-forge/osx-64/mysql-common-8.0.32-h7ebae80_0.conda#c38eebf92d4b044a18f00eddd3e2c7c9
 https://conda.anaconda.org/conda-forge/osx-64/mysql-connector-c-6.1.11-h0f02589_1007.tar.bz2#de4b8b14c3d7e41de6a6b59b3ab1fbaa
-https://conda.anaconda.org/bioconda/osx-64/ncbi-vdb-3.1.1-h85dcccf_0.tar.bz2#71c42f95e6d969b7529e1dc8c4c4deb4
+https://conda.anaconda.org/bioconda/osx-64/ncbi-vdb-3.1.1-hac4f329_1.tar.bz2#ae9f2a45a5dca6ff09e444c7d4a3b655
 https://conda.anaconda.org/conda-forge/osx-64/pcre-8.45-he49afe7_0.tar.bz2#0526850419e04ac003bc0b65a78dc4cc
 https://conda.anaconda.org/bioconda/noarch/perl-carp-1.38-pl5321hdfd78af_4.tar.bz2#e4cbd5d05ff5018e31668ae0b4a47a05
 https://conda.anaconda.org/bioconda/osx-64/perl-compress-raw-bzip2-2.201-pl5321h9722bc1_0.tar.bz2#4c703ab9164ee0caa175690828397a60
@@ -147,7 +147,7 @@ https://conda.anaconda.org/bioconda/osx-64/htslib-1.16-h567f53e_0.tar.bz2#bd9c90
 https://conda.anaconda.org/conda-forge/noarch/humanfriendly-10.0-pyhd8ed1ab_6.conda#2ed1fe4b9079da97c44cfe9c2e5078fd
 https://conda.anaconda.org/conda-forge/osx-64/ld64_osx-64-609-hc6b1d1e_10.tar.bz2#4a5fdb42da6da735f2f4778d63b4b9f0
 https://conda.anaconda.org/conda-forge/osx-64/libclang-cpp12-12.0.1-default_he082bbe_4.tar.bz2#2e53c06139a0b687f970e0538c0c4fd7
-https://conda.anaconda.org/conda-forge/osx-64/libopenblas-0.3.27-openmp_hfef2a42_0.conda#00237c9c7f2cb6725fe2960680a6e225
+https://conda.anaconda.org/conda-forge/osx-64/libopenblas-0.3.27-openmp_h8869122_1.conda#c0798ad76ddd730dade6ff4dff66e0b5
 https://conda.anaconda.org/conda-forge/osx-64/llvm-tools-12.0.1-hd011deb_2.tar.bz2#9864ddf73340515b93c2ff18da33ec8d
 https://conda.anaconda.org/conda-forge/osx-64/mysql-devel-8.0.32-h7ebae80_0.conda#40a67c7d39eb096bf5ea33902db1c314
 https://conda.anaconda.org/conda-forge/osx-64/mysql-server-8.0.32-ha134c4c_0.conda#a670483ac75d19fcc527de2a96058615
@@ -162,7 +162,7 @@ https://conda.anaconda.org/bioconda/osx-64/pysam-0.20.0-py310h958c131_0.tar.bz2#
 https://conda.anaconda.org/conda-forge/noarch/python-tzdata-2024.1-pyhd8ed1ab_0.conda#98206ea9954216ee7540f0c773f2104d
 https://conda.anaconda.org/conda-forge/noarch/pytz-2024.1-pyhd8ed1ab_0.conda#3eeeeb9e4827ace8c0c1419c85d590ad
 https://conda.anaconda.org/conda-forge/osx-64/pyyaml-6.0.1-py310h6729b98_1.conda#d964cec3e7972e44bc4a328134b9eaf1
-https://conda.anaconda.org/conda-forge/noarch/setuptools-70.1.1-pyhd8ed1ab_0.conda#985e9e86e1b0fc75a74a9bfab9309ef7
+https://conda.anaconda.org/conda-forge/noarch/setuptools-70.3.0-pyhd8ed1ab_0.conda#693bb57e8f92120caa956898065f3627
 https://conda.anaconda.org/conda-forge/noarch/six-1.16.0-pyh6c4a22f_0.tar.bz2#e5f25f8dbc060e9a8d912e432202afc2
 https://conda.anaconda.org/bioconda/osx-64/viennarna-2.6.4-py310pl5321hb5a725e_0.tar.bz2#6852d7b92265aa9865387826d7b36277
 https://conda.anaconda.org/conda-forge/noarch/wheel-0.43.0-pyhd8ed1ab_1.conda#0b5293a157c2b5cd513dd1b03d8d3aae
@@ -212,7 +212,7 @@ https://conda.anaconda.org/bioconda/noarch/perl-libwww-perl-6.67-pl5321hdfd78af_
 https://conda.anaconda.org/bioconda/osx-64/pybedtools-0.10.0-py310h0b3aad1_1.tar.bz2#ade72e96268dba2ca0ba1f728dfe4c43
 https://conda.anaconda.org/conda-forge/osx-64/scipy-1.14.0-py310h35d8cac_1.conda#c261d35d90ab2d683b13d140edd907af
 https://conda.anaconda.org/conda-forge/osx-64/compiler-rt-12.0.1-he01351e_0.tar.bz2#aa2cb3794dae4a09f19c3b7169b5df1f
-https://conda.anaconda.org/pcgr/noarch/pcgr-2.0.1-py_0.tar.bz2#eec67f68553213c0227d7d9fc3b9dcdb
+https://conda.anaconda.org/pcgr/noarch/pcgr-2.0.2-py_0.tar.bz2#5bc257e15d72598686e5a627889a2d2d
 https://conda.anaconda.org/bioconda/noarch/perl-xml-dom-1.46-pl5321hdfd78af_1.tar.bz2#45b7ce435727456727f45b3e2121b23b
 https://conda.anaconda.org/bioconda/osx-64/t-coffee-12.00.7fb08c2-h26a2512_0.tar.bz2#fe6f3532da0e9d3868b58ecd07f33744
 https://conda.anaconda.org/bioconda/noarch/vcf2tsvpy-0.6.1-pyhda70652_0.tar.bz2#cb9612a58cefb7e2a144c759027c0a94
diff --git a/conda/env/lock/pcgrr-linux-64.lock b/conda/env/lock/pcgrr-linux-64.lock
index b87a25c7..ba06644d 100644
--- a/conda/env/lock/pcgrr-linux-64.lock
+++ b/conda/env/lock/pcgrr-linux-64.lock
@@ -1,9 +1,10 @@
 # Generated by conda-lock.
 # platform: linux-64
-# input_hash: 98ef74817c616d2aa423017ffdb2e9b9b740899c42fff240b36d32b3b7fc4e09
+# input_hash: ca17b4d0eef40be5eb76dd29a39e02f3b1ce64802f5fbe4040ce833d7a80b493
 @EXPLICIT
 https://conda.anaconda.org/conda-forge/linux-64/_libgcc_mutex-0.1-conda_forge.tar.bz2#d7c89558ba9fa0495403155b64376d81
 https://conda.anaconda.org/conda-forge/noarch/_r-mutex-1.0.1-anacondar_1.tar.bz2#19f9db5f4f1b7f5ef5f6d67207f25f38
+https://conda.anaconda.org/conda-forge/noarch/_sysroot_linux-64_curr_repodata_hack-3-h69a702a_16.conda#1c005af0c6ff22814b7c52ee448d4bea
 https://conda.anaconda.org/conda-forge/linux-64/ca-certificates-2024.7.4-hbcca054_0.conda#23ab7665c5f63cfb9f1f6195256daac6
 https://conda.anaconda.org/conda-forge/linux-64/dart-sass-1.58.3-ha770c72_1.conda#d54982a58cd9be3d00a7efe76ba6f60c
 https://conda.anaconda.org/conda-forge/linux-64/esbuild-0.19.2-ha770c72_0.conda#8fa87b764cf6143cb66e9cc3548b186a
@@ -11,22 +12,22 @@ https://conda.anaconda.org/conda-forge/noarch/font-ttf-dejavu-sans-mono-2.37-hab
 https://conda.anaconda.org/conda-forge/noarch/font-ttf-inconsolata-3.000-h77eed37_0.tar.bz2#34893075a5c9e55cdafac56607368fc6
 https://conda.anaconda.org/conda-forge/noarch/font-ttf-source-code-pro-2.038-h77eed37_0.tar.bz2#4d59c254e01d9cde7957100457e2d5fb
 https://conda.anaconda.org/conda-forge/noarch/font-ttf-ubuntu-0.83-h77eed37_2.conda#cbbe59391138ea5ad3658c76912e147f
-https://conda.anaconda.org/conda-forge/noarch/kernel-headers_linux-64-2.6.32-he073ed8_17.conda#d731b543793afc0433c4fd593e693fce
 https://conda.anaconda.org/conda-forge/linux-64/ld_impl_linux-64-2.40-hf3520f5_7.conda#b80f2f396ca2c28b8c14c437a4ed1e74
-https://conda.anaconda.org/conda-forge/linux-64/pandoc-3.1.11.1-ha770c72_0.conda#0e2f14aff42adf4675bcd5335d644a5f
+https://conda.anaconda.org/conda-forge/linux-64/pandoc-3.1.12.3-ha770c72_0.conda#cdea66892b19a454f939487318b6c517
 https://conda.anaconda.org/conda-forge/linux-64/python_abi-3.12-4_cp312.conda#dccc2d142812964fcc6abdc97b672dff
 https://conda.anaconda.org/conda-forge/noarch/tzdata-2024a-h0c530f3_0.conda#161081fc7cec0bfda0d86d7cb595f8d8
 https://conda.anaconda.org/conda-forge/noarch/fonts-conda-forge-1-0.tar.bz2#f766549260d6815b0c52253f1fb1bb29
+https://conda.anaconda.org/conda-forge/noarch/kernel-headers_linux-64-3.10.0-h4a8ded7_16.conda#ff7f38675b226cfb855aebfc32a13e31
 https://conda.anaconda.org/conda-forge/noarch/libgcc-devel_linux-64-14.1.0-h5d3d1c9_100.conda#6d4f65dc440f7b3422113b135be19703
 https://conda.anaconda.org/conda-forge/linux-64/libgomp-14.1.0-h77fa898_0.conda#ae061a5ed5f05818acdf9adab72c146d
 https://conda.anaconda.org/conda-forge/noarch/libstdcxx-devel_linux-64-14.1.0-h5d3d1c9_100.conda#cedc62fd8c4cf28f23d3cd5db7839e99
-https://conda.anaconda.org/conda-forge/noarch/sysroot_linux-64-2.12-he073ed8_17.conda#595db67e32b276298ff3d94d07d47fbf
 https://conda.anaconda.org/conda-forge/linux-64/_openmp_mutex-4.5-2_gnu.tar.bz2#73aaf86a425cc6e73fcf236a5a46396d
-https://conda.anaconda.org/conda-forge/linux-64/binutils_impl_linux-64-2.40-ha1999f0_7.conda#3f840c7ed70a96b5ebde8044b2f36f32
 https://conda.anaconda.org/conda-forge/noarch/fonts-conda-ecosystem-1-0.tar.bz2#fee5683a3f04bd15cbd8318b096a27ab
+https://conda.anaconda.org/conda-forge/noarch/sysroot_linux-64-2.17-h4a8ded7_16.conda#223fe8a3ff6d5e78484a9d58eb34d055
+https://conda.anaconda.org/conda-forge/linux-64/binutils_impl_linux-64-2.40-ha1999f0_7.conda#3f840c7ed70a96b5ebde8044b2f36f32
 https://conda.anaconda.org/conda-forge/linux-64/libgcc-ng-14.1.0-h77fa898_0.conda#ca0fad6a41ddaef54a153b78eccb5037
-https://conda.anaconda.org/conda-forge/linux-64/bzip2-1.0.8-hd590300_5.conda#69b8b6202a07720f448be700e300ccf4
-https://conda.anaconda.org/conda-forge/linux-64/c-ares-1.28.1-hd590300_0.conda#dcde58ff9a1f30b0037a2315d1846d1f
+https://conda.anaconda.org/conda-forge/linux-64/bzip2-1.0.8-h4bc722e_7.conda#62ee74e96c5ebb0af99386de58cf9553
+https://conda.anaconda.org/conda-forge/linux-64/c-ares-1.32.2-h4bc722e_0.conda#8024af1ee7078e37fa3101c0a0296af2
 https://conda.anaconda.org/conda-forge/linux-64/deno-1.37.2-h335b0a9_1.conda#50fe6d0064adfd83846a6f9c87da03e3
 https://conda.anaconda.org/conda-forge/linux-64/fribidi-1.0.10-h36c2ea0_0.tar.bz2#ac7bc6a654f8f41b352b38f4051135f8
 https://conda.anaconda.org/conda-forge/linux-64/keyutils-1.6.1-h166bdaf_0.tar.bz2#30186d27e2c9fa62b45fb1476b7200e3
@@ -84,11 +85,11 @@ https://conda.anaconda.org/conda-forge/linux-64/gcc_impl_linux-64-14.1.0-h3c94d9
 https://conda.anaconda.org/bioconda/linux-64/jq-1.5-0.tar.bz2#f380e0813e0752164752d9a9c63667d7
 https://conda.anaconda.org/conda-forge/linux-64/krb5-1.21.3-h659f571_0.conda#3f43953b7d3fb3aaa1d0d0723d91e368
 https://conda.anaconda.org/conda-forge/linux-64/libglib-2.80.3-h8a4344b_1.conda#6ea440297aacee4893f02ad759e6ffbc
-https://conda.anaconda.org/conda-forge/linux-64/libopenblas-0.3.27-pthreads_h413a1c8_0.conda#a356024784da6dfd4683dc5ecf45b155
+https://conda.anaconda.org/conda-forge/linux-64/libopenblas-0.3.27-pthreads_hac2b453_1.conda#ae05ece66d3924ac3d48b4aa3fa96cec
 https://conda.anaconda.org/conda-forge/linux-64/libtiff-4.6.0-h1dd3fc0_3.conda#66f03896ffbe1a110ffda05c7a856504
-https://conda.anaconda.org/conda-forge/linux-64/libxml2-2.12.7-hc051c1a_1.conda#340278ded8b0dc3a73f3660bbb0adbc6
+https://conda.anaconda.org/conda-forge/linux-64/libxml2-2.12.7-h4c95cb1_3.conda#0ac9aff6010a7751961c8e4b863a40e7
 https://conda.anaconda.org/conda-forge/linux-64/python-3.12.4-h194c7f8_0_cpython.conda#d73490214f536cccb5819e9873048c92
-https://conda.anaconda.org/conda-forge/linux-64/quarto-1.4.550-ha770c72_1.conda#b7b89be76bcdab239f7956e5fc2727ab
+https://conda.anaconda.org/conda-forge/linux-64/quarto-1.4.557-ha770c72_0.conda#564f00d6feca800e6f1ecffd8ca21ea0
 https://conda.anaconda.org/conda-forge/linux-64/tktable-2.10-h8bc8fbc_6.conda#dff3627fec2c0584ded391205295abf0
 https://conda.anaconda.org/conda-forge/linux-64/xorg-libx11-1.8.9-hb711507_1.conda#4a6d410296d7e39f00bacdee7df046e9
 https://conda.anaconda.org/conda-forge/noarch/argcomplete-3.4.0-pyhd8ed1ab_0.conda#9f736cae0da3365a4dbbfbadfac9f3a2
@@ -98,9 +99,9 @@ https://conda.anaconda.org/conda-forge/linux-64/gxx_impl_linux-64-14.1.0-h2879b8
 https://conda.anaconda.org/conda-forge/linux-64/libblas-3.9.0-22_linux64_openblas.conda#1a2a0cd3153464fee6646f3dd6dad9b8
 https://conda.anaconda.org/conda-forge/linux-64/libcurl-8.8.0-hca28451_1.conda#b8afb3e3cb3423cc445cf611ab95fdb0
 https://conda.anaconda.org/conda-forge/linux-64/pyyaml-6.0.1-py312h98912ed_1.conda#e3fd78d8d490af1d84763b9fe3f2e552
-https://conda.anaconda.org/conda-forge/noarch/setuptools-70.1.1-pyhd8ed1ab_0.conda#985e9e86e1b0fc75a74a9bfab9309ef7
+https://conda.anaconda.org/conda-forge/noarch/setuptools-70.3.0-pyhd8ed1ab_0.conda#693bb57e8f92120caa956898065f3627
 https://conda.anaconda.org/conda-forge/noarch/toml-0.10.2-pyhd8ed1ab_0.tar.bz2#f832c45a477c78bebd107098db465095
-https://conda.anaconda.org/conda-forge/noarch/tomlkit-0.12.5-pyha770c72_0.conda#e5dde5caf905e9d95895e05f94967e14
+https://conda.anaconda.org/conda-forge/noarch/tomlkit-0.13.0-pyha770c72_0.conda#810ba6f354ddef812d0ddc4669cc8de6
 https://conda.anaconda.org/conda-forge/noarch/xmltodict-0.13.0-pyhd8ed1ab_0.tar.bz2#b5b33faed6ed2b4ba47a690b8f5c0818
 https://conda.anaconda.org/conda-forge/linux-64/xorg-libxext-1.3.4-h0b41bf4_2.conda#82b6df12252e6f32402b96dacc656fec
 https://conda.anaconda.org/conda-forge/linux-64/xorg-libxrender-0.9.11-hd590300_0.conda#ed67c36f215b310412b2af935bf3e530
@@ -158,7 +159,7 @@ https://conda.anaconda.org/conda-forge/noarch/r-labeling-0.4.3-r43hc72bb7e_1.con
 https://conda.anaconda.org/conda-forge/linux-64/r-lattice-0.22_6-r43hb1dbf0f_1.conda#e42a7ddaeeea0096c4f6df18fb5274e3
 https://conda.anaconda.org/conda-forge/linux-64/r-lazyeval-0.2.2-r43hb1dbf0f_5.conda#5332bc619a13ca173a49cb602489a9df
 https://conda.anaconda.org/conda-forge/noarch/r-listenv-0.9.1-r43hc72bb7e_1.conda#ec5e5ed484ed53445c5ae5debc3f3f53
-https://conda.anaconda.org/conda-forge/linux-64/r-log4r-0.4.3-r43h57805ef_1.conda#ef2fa138bd3ff5484ce7d43319c0d781
+https://conda.anaconda.org/conda-forge/linux-64/r-log4r-0.4.3-r43hdb488b9_2.conda#e5739f218d567d11d8069cd4928f7d93
 https://conda.anaconda.org/conda-forge/linux-64/r-lpsolve-5.6.20-r43hb1dbf0f_1.conda#5b5cad1e4911d2abbbf53917b935b1ee
 https://conda.anaconda.org/conda-forge/linux-64/r-magrittr-2.0.3-r43hb1dbf0f_3.conda#fc61bcf37e59037b486c8841a704e9da
 https://conda.anaconda.org/conda-forge/linux-64/r-mass-7.3_60.0.1-r43hb1dbf0f_1.conda#c3c9184486ccabe19b86aba11351652e
@@ -190,7 +191,7 @@ https://conda.anaconda.org/conda-forge/noarch/r-shape-1.4.6.1-r43ha770c72_1.cond
 https://conda.anaconda.org/conda-forge/noarch/r-snow-0.4_4-r43hc72bb7e_3.conda#60eeeef67921f38a80c1778eae3bbbb9
 https://conda.anaconda.org/conda-forge/linux-64/r-sourcetools-0.1.7_1-r43ha18555a_2.conda#ac984cdfeb93aecef6e2d5942a6d9ab3
 https://conda.anaconda.org/conda-forge/noarch/r-squarem-2021.1-r43hc72bb7e_3.conda#7540130cd26e12a02742dac9ddc184d6
-https://conda.anaconda.org/conda-forge/linux-64/r-stringi-1.8.4-r43hbd1cc82_1.conda#0639b10d7e66e5c80d8ce8dd1ee7bf4f
+https://conda.anaconda.org/conda-forge/linux-64/r-stringi-1.8.4-r43ha8ce623_2.conda#f3cd6969f6b685effb07fa15ce2a0554
 https://conda.anaconda.org/conda-forge/linux-64/r-sys-3.4.2-r43hb1dbf0f_2.conda#97ac2486210aeff0afb5f4c5bcecf5d4
 https://conda.anaconda.org/conda-forge/noarch/r-timedate-4032.109-r43hc72bb7e_1.conda#0e901aea4b8040ddf8b0a612fc283407
 https://conda.anaconda.org/conda-forge/linux-64/r-utf8-1.2.4-r43hb1dbf0f_1.conda#6337f1f20dea2a325142d2b7b1b7d42c
@@ -206,7 +207,7 @@ https://conda.anaconda.org/bioconda/noarch/bioconductor-genomeinfodbdata-1.2.11-
 https://conda.anaconda.org/bioconda/noarch/bioconductor-matrixgenerics-1.14.0-r43hdfd78af_3.tar.bz2#c79f36cc0cd464874aefd50a700d0079
 https://conda.anaconda.org/bioconda/linux-64/bioconductor-rhtslib-2.4.0-r43ha9d7317_2.tar.bz2#f54f24c26d9e1eb7d582f2806c3b6824
 https://conda.anaconda.org/bioconda/linux-64/bioconductor-s4vectors-0.40.2-r43ha9d7317_2.tar.bz2#6aa465e83dabb7ed5b853519d8a334e4
-https://conda.anaconda.org/conda-forge/noarch/r-argparse-2.2.3-r43hc72bb7e_0.conda#48ca12b4fb578b31e020d1d657f26354
+https://conda.anaconda.org/conda-forge/noarch/r-argparse-2.2.3-r43hc72bb7e_1.conda#4a112f5abf0991d2f72d0efc7abbfc04
 https://conda.anaconda.org/conda-forge/linux-64/r-askpass-1.2.0-r43hb1dbf0f_1.conda#01e6c23b754802bb1f68664e56de58fc
 https://conda.anaconda.org/conda-forge/noarch/r-assertable-0.2.8-r43hc72bb7e_2.conda#36f455211da59b0f91b9907f31c3cf96
 https://conda.anaconda.org/conda-forge/noarch/r-bibtex-0.5.1-r43hc72bb7e_2.conda#4514eabc038859b5ae5e119208b23f6d
@@ -223,18 +224,18 @@ https://conda.anaconda.org/conda-forge/noarch/r-lambda.r-1.2.4-r43hc72bb7e_4.con
 https://conda.anaconda.org/conda-forge/linux-64/r-later-1.3.2-r43ha18555a_1.conda#9994dcb7378eada8b5388aaee3b27aa6
 https://conda.anaconda.org/conda-forge/noarch/r-lifecycle-1.0.4-r43hc72bb7e_0.conda#291d2fb68ea1b181644b40d6743ae000
 https://conda.anaconda.org/conda-forge/linux-64/r-limsolve-1.5.7.1-r43hc4980d5_1.conda#6f2d9a49a30b352f08e5e4def19c9e4f
-https://conda.anaconda.org/conda-forge/linux-64/r-matrix-1.6_5-r43h316c678_0.conda#8146ef1b3c54e1a484822085d39357b0
+https://conda.anaconda.org/conda-forge/linux-64/r-matrix-1.6_5-r43he966344_1.conda#df8a1175a62460e02dbf340966cbfeab
 https://conda.anaconda.org/conda-forge/linux-64/r-modelmetrics-1.2.2.2-r43ha503ecb_3.conda#47078c91f46dc3ca660a4fa4b3a6f8b1
 https://conda.anaconda.org/conda-forge/noarch/r-munsell-0.5.1-r43hc72bb7e_1.conda#8b2f9bb8064ae0896ffedd984661a2d5
 https://conda.anaconda.org/conda-forge/linux-64/r-nlme-3.1_165-r43hbcb9c34_1.conda#ae3f1ce6e352a9089f639044764c533f
 https://conda.anaconda.org/conda-forge/linux-64/r-nnet-7.3_19-r43hb1dbf0f_2.conda#bb0d554d900f7bbc55d23f3a1db22668
-https://conda.anaconda.org/conda-forge/linux-64/r-openxlsx2-1.8-r43h0d4f4ea_0.conda#2ba916100f047653eba6223c6ba084f4
+https://conda.anaconda.org/conda-forge/linux-64/r-openxlsx2-1.8-r43h0d4f4ea_1.conda#bf55c8646be483b0ffdba05c29e0ace8
 https://conda.anaconda.org/conda-forge/linux-64/r-pki-0.1_14-r43hb1dbf0f_0.conda#58c4dc882730c0d96ca09e58be0150d8
 https://conda.anaconda.org/conda-forge/linux-64/r-plyr-1.8.9-r43ha18555a_1.conda#d93aedee4cc78f78413969b1e891842c
 https://conda.anaconda.org/conda-forge/noarch/r-prettyunits-1.2.0-r43hc72bb7e_1.conda#cf655364ee1c16ad385e829987a67458
 https://conda.anaconda.org/conda-forge/linux-64/r-processx-3.8.4-r43hb1dbf0f_1.conda#b9dcc14c0f4866d8593bb5fbd3f1c447
 https://conda.anaconda.org/conda-forge/noarch/r-progressr-0.14.0-r43hc72bb7e_1.conda#ce5d69c0d781106778e951b44313404d
-https://conda.anaconda.org/conda-forge/linux-64/r-rcurl-1.98_1.14-r43hf9611b0_0.conda#efa65e9a6648da5ef77f7ede0b3afb29
+https://conda.anaconda.org/conda-forge/linux-64/r-rcurl-1.98_1.16-r43h6b349a7_0.conda#88bf36e10f18d1937d102e205100d792
 https://conda.anaconda.org/conda-forge/linux-64/r-timechange-0.3.0-r43ha18555a_1.conda#da155dc726414cca04cdc76a297c4463
 https://conda.anaconda.org/conda-forge/noarch/r-tinytex-0.51-r43hc72bb7e_1.conda#35ba2dc42178aa25fcf020aa39491d0e
 https://conda.anaconda.org/conda-forge/linux-64/r-tzdb-0.4.0-r43ha18555a_2.conda#af670d1acc46c7aa0973ad190e0f52a0
@@ -242,21 +243,21 @@ https://conda.anaconda.org/conda-forge/linux-64/r-xml2-1.3.6-r43hbfba7a4_1.conda
 https://conda.anaconda.org/bioconda/noarch/bioconductor-biocio-1.12.0-r43hdfd78af_0.tar.bz2#bff7970f9c895f54216ca423a271e3dc
 https://conda.anaconda.org/bioconda/linux-64/bioconductor-iranges-2.36.0-r43ha9d7317_2.tar.bz2#cca51afd40439bea147c1adf9857bec0
 https://conda.anaconda.org/conda-forge/noarch/r-doparallel-1.0.17-r43hc72bb7e_3.conda#4206403c7e833e5c4eaa75c7d110ca2a
-https://conda.anaconda.org/conda-forge/linux-64/r-e1071-1.7_14-r43ha503ecb_0.conda#99f29679579f01d7ffdf0a6d47495eb2
+https://conda.anaconda.org/conda-forge/linux-64/r-e1071-1.7_14-r43h0d4f4ea_1.conda#35e996879ece470a478de9c4a2dc1f0e
 https://conda.anaconda.org/conda-forge/noarch/r-futile.logger-1.4.3-r43hc72bb7e_1006.conda#dbfd04b54b6ac781070393f2184b3c6d
 https://conda.anaconda.org/conda-forge/noarch/r-future-1.33.2-r43h785f33e_1.conda#dd5dbf92b6b19e4261fb34299c4475c5
 https://conda.anaconda.org/conda-forge/noarch/r-gtable-0.3.5-r43hc72bb7e_0.conda#4afa6b3bc18ef585bac26420528ed1de
 https://conda.anaconda.org/conda-forge/linux-64/r-htmltools-0.5.8.1-r43ha18555a_1.conda#7b26688542e1b7a39fc62affeef9d32e
-https://conda.anaconda.org/conda-forge/noarch/r-knitr-1.47-r43hc72bb7e_1.conda#967490c6696683f4e6f257ea1a1ece49
+https://conda.anaconda.org/conda-forge/noarch/r-knitr-1.48-r43hc72bb7e_0.conda#78b89f7a7df2bacfa367589fc95a36db
 https://conda.anaconda.org/conda-forge/linux-64/r-lubridate-1.9.3-r43h57805ef_0.conda#48f220862d7b0ac7d1397f8c6601fb70
 https://conda.anaconda.org/conda-forge/noarch/r-memoise-2.0.1-r43hc72bb7e_3.conda#98e3d2eb6635a5f7b8af487f47184a98
-https://conda.anaconda.org/conda-forge/linux-64/r-mgcv-1.9_1-r43h316c678_0.conda#c73d9ed0dc98182d712cbea33a3e5d59
+https://conda.anaconda.org/conda-forge/linux-64/r-mgcv-1.9_1-r43h0d28552_1.conda#154d840fb734a3f80a5ef623b52ff6cd
 https://conda.anaconda.org/conda-forge/linux-64/r-openssl-2.2.0-r43hd7d0243_0.conda#60f961514ecc3ee1fd7b1afd6ea853ab
 https://conda.anaconda.org/conda-forge/linux-64/r-proc-1.18.5-r43ha18555a_1.conda#1d7db1e76a22b4bee1e95d67ef62bfd9
 https://conda.anaconda.org/conda-forge/linux-64/r-promises-1.3.0-r43ha18555a_1.conda#1feee229681daba904a07f0e96f549be
 https://conda.anaconda.org/bioconda/linux-64/r-restfulr-0.0.15-r43h56115f1_4.tar.bz2#98d1b64d34553c9cafe9ad01bd956844
 https://conda.anaconda.org/conda-forge/noarch/r-scales-1.3.0-r43hc72bb7e_0.conda#508360956e18c2b0cc18968cdb786c78
-https://conda.anaconda.org/conda-forge/linux-64/r-survival-3.7_0-r43hb1dbf0f_0.conda#4fb502d2c2e54c9d1f65165aa1d80d2e
+https://conda.anaconda.org/conda-forge/linux-64/r-survival-3.7_0-r43hdb488b9_1.conda#06d0a4ee19176ea1a9a0ec1f767dd2ae
 https://conda.anaconda.org/conda-forge/linux-64/r-vctrs-0.6.5-r43ha503ecb_0.conda#e398bd0451e6350a876a8561f8e90682
 https://conda.anaconda.org/bioconda/linux-64/bioconductor-biocparallel-1.36.0-r43hf17093f_2.tar.bz2#6e03fcbba328db0b9f2a722ce663e916
 https://conda.anaconda.org/bioconda/noarch/bioconductor-genomeinfodb-1.38.1-r43hdfd78af_1.tar.bz2#03e20a01b672b693c9470dec80d83993
@@ -281,7 +282,7 @@ https://conda.anaconda.org/bioconda/linux-64/bioconductor-biostrings-2.70.1-r43h
 https://conda.anaconda.org/bioconda/linux-64/bioconductor-genomicranges-1.54.1-r43ha9d7317_2.tar.bz2#01031256b035b2d4a15c14b690be39aa
 https://conda.anaconda.org/bioconda/linux-64/bioconductor-sparsearray-1.2.2-r43ha9d7317_2.tar.bz2#41f1e8c1cfb7ff594e923c05e02d9ecb
 https://conda.anaconda.org/conda-forge/noarch/r-bslib-0.7.0-r43hc72bb7e_0.conda#6e2bfdc782284259390d09bb083142b2
-https://conda.anaconda.org/conda-forge/noarch/r-lava-1.7.3-r43hc72bb7e_0.conda#813b11bcb3baa5bac2ff27b63b94a0b2
+https://conda.anaconda.org/conda-forge/noarch/r-lava-1.7.3-r43hc72bb7e_1.conda#3d13916ab4fa9a82daaf27db47ced7a0
 https://conda.anaconda.org/conda-forge/noarch/r-pkgmaker-0.32.10-r43hc72bb7e_1.conda#ecc7c90afc8ae9f8725550acdb5454f9
 https://conda.anaconda.org/conda-forge/noarch/r-progress-1.2.3-r43hc72bb7e_0.conda#49c52ccafe27439ac6b69a74c626b3a8
 https://conda.anaconda.org/conda-forge/linux-64/r-reshape2-1.4.4-r43ha503ecb_3.conda#dcf98bb7191b4e45cb199577286705c7
@@ -326,5 +327,5 @@ https://conda.anaconda.org/bioconda/noarch/bioconductor-bsgenome.hsapiens.ucsc.h
 https://conda.anaconda.org/bioconda/noarch/bioconductor-genomicfeatures-1.54.1-r43hdfd78af_0.tar.bz2#445ea419486180673fffc192b5fe8edb
 https://conda.anaconda.org/bioconda/linux-64/bioconductor-variantannotation-1.48.1-r43ha9d7317_1.tar.bz2#01c0b8e76583c3f8872e3181dd06ffbd
 https://conda.anaconda.org/bioconda/noarch/bioconductor-mutationalpatterns-3.12.0-r43hdfd78af_0.tar.bz2#d22030798f7d464ddb092e4651625210
-https://conda.anaconda.org/pcgr/noarch/r-pcgrr-2.0.1-r43_0.tar.bz2#d5c0015b573b871d6bd4375c20f101f8
+https://conda.anaconda.org/pcgr/noarch/r-pcgrr-2.0.2-r43_0.tar.bz2#7bacc2ff007b4004ca32e4b594d21e58
 https://conda.anaconda.org/pcgr/noarch/r-cpsr-2.0.1-r43_0.tar.bz2#5bab752f34e3e1d91e0225cf7a4a8251
diff --git a/conda/env/lock/pcgrr-osx-64.lock b/conda/env/lock/pcgrr-osx-64.lock
index e57dc81f..b38241f4 100644
--- a/conda/env/lock/pcgrr-osx-64.lock
+++ b/conda/env/lock/pcgrr-osx-64.lock
@@ -1,10 +1,8 @@
 # Generated by conda-lock.
 # platform: osx-64
-# input_hash: 31dc1220de01e9e7e29d0299e06e6a2d54739f674143f5b48cfb7182699d5c97
+# input_hash: 6f3f9b8e7ab60bf6fe2e30650650bf05b8a5965cf076e3886444714e683b04c3
 @EXPLICIT
 https://conda.anaconda.org/conda-forge/noarch/_r-mutex-1.0.1-anacondar_1.tar.bz2#19f9db5f4f1b7f5ef5f6d67207f25f38
-https://conda.anaconda.org/conda-forge/osx-64/bzip2-1.0.8-h10d778d_5.conda#6097a6ca9ada32699b5fc4312dd6ef18
-https://conda.anaconda.org/conda-forge/osx-64/c-ares-1.28.1-h10d778d_0.conda#d5eb7992227254c0e9a0ce71151f0079
 https://conda.anaconda.org/conda-forge/osx-64/ca-certificates-2024.7.4-h8857fd0_0.conda#7df874a4b05b2d2b82826190170eaa0f
 https://conda.anaconda.org/conda-forge/osx-64/dart-sass-1.58.3-h694c41f_1.conda#5151299fff69a62e792c79d1b726a470
 https://conda.anaconda.org/conda-forge/osx-64/esbuild-0.19.2-h694c41f_0.conda#61cc0fd0aa08d9a37b2df02b88c00203
@@ -26,16 +24,18 @@ https://conda.anaconda.org/conda-forge/osx-64/libjpeg-turbo-3.0.0-h0dc2134_1.con
 https://conda.anaconda.org/conda-forge/osx-64/libwebp-base-1.4.0-h10d778d_0.conda#b2c0047ea73819d992484faacbbe1c24
 https://conda.anaconda.org/conda-forge/osx-64/make-4.3-h22f3db7_1.tar.bz2#ac4a1dd58e6d821c518ae0011e8592b7
 https://conda.anaconda.org/conda-forge/osx-64/ncurses-6.5-h5846eda_0.conda#02a888433d165c99bf09784a7b14d900
-https://conda.anaconda.org/conda-forge/osx-64/pandoc-3.1.11.1-h694c41f_0.conda#6cff44b16d1231fe9682c64d12ab66a5
+https://conda.anaconda.org/conda-forge/osx-64/pandoc-3.1.12.3-h694c41f_0.conda#dbd54d0b1e33c2c2713ca41fb32c51f6
 https://conda.anaconda.org/conda-forge/osx-64/python_abi-3.12-4_cp312.conda#87201ac4314b911b74197e588cca3639
 https://conda.anaconda.org/conda-forge/noarch/tzdata-2024a-h0c530f3_0.conda#161081fc7cec0bfda0d86d7cb595f8d8
 https://conda.anaconda.org/conda-forge/osx-64/xz-5.2.6-h775f41a_0.tar.bz2#a72f9d4ea13d55d745ff1ed594747f10
 https://conda.anaconda.org/conda-forge/osx-64/yaml-0.2.5-h0d85af4_2.tar.bz2#d7e08fcf8259d742156188e8762b4d20
+https://conda.anaconda.org/conda-forge/osx-64/bzip2-1.0.8-hfdf4475_7.conda#7ed4301d437b59045be7e051a0308211
+https://conda.anaconda.org/conda-forge/osx-64/c-ares-1.32.2-h51dda26_0.conda#be4a9b58fcf1374aeb79e873c1166e19
 https://conda.anaconda.org/conda-forge/osx-64/deno-1.37.2-h51b076b_1.conda#d452ae5711d2261a9a2600c1c9cb95f1
 https://conda.anaconda.org/conda-forge/osx-64/expat-2.6.2-h73e2aa4_0.conda#dc0882915da2ec74696ad87aa2350f27
 https://conda.anaconda.org/conda-forge/noarch/fonts-conda-forge-1-0.tar.bz2#f766549260d6815b0c52253f1fb1bb29
 https://conda.anaconda.org/bioconda/osx-64/jq-1.5-0.tar.bz2#ba074d94b6fcab0caffd3ab32d8c2757
-https://conda.anaconda.org/conda-forge/osx-64/libcxx-17.0.6-heb59cac_3.conda#ef15f182e353155497e13726b915bfc4
+https://conda.anaconda.org/conda-forge/osx-64/libcxx-18.1.8-hef8daea_0.conda#4101cde4241c92aeac310d65e6791579
 https://conda.anaconda.org/conda-forge/osx-64/libedit-3.1.20191231-h0678c8f_2.tar.bz2#6016a8a1d0e63cac3de2c352cd40208b
 https://conda.anaconda.org/conda-forge/osx-64/libintl-0.22.5-h5ff76d1_2.conda#3fb6774cb8cdbb93a6013b67bcf9716d
 https://conda.anaconda.org/conda-forge/osx-64/libzlib-1.3.1-h87427d6_1.conda#b7575b5aa92108dcc9aaab0f05f2dbce
@@ -55,7 +55,7 @@ https://conda.anaconda.org/conda-forge/osx-64/libnghttp2-1.58.0-h64cf6d3_1.conda
 https://conda.anaconda.org/conda-forge/osx-64/libpng-1.6.43-h92b6c6a_0.conda#65dcddb15965c9de2c0365cb14910532
 https://conda.anaconda.org/conda-forge/osx-64/libsqlite-3.46.0-h1b8f9f3_0.conda#5dadfbc1a567fe6e475df4ce3148be09
 https://conda.anaconda.org/conda-forge/osx-64/libssh2-1.11.0-hd019ec5_0.conda#ca3a72efba692c59a90d4b9fc0dfe774
-https://conda.anaconda.org/conda-forge/osx-64/libxml2-2.12.7-h3e169fe_1.conda#ddb63049aa7bd9f08f2cdc5a1c144d1a
+https://conda.anaconda.org/conda-forge/osx-64/libxml2-2.12.7-hc603aa4_3.conda#c188d96aea8eaa16efec573fe36a9a13
 https://conda.anaconda.org/conda-forge/osx-64/pcre2-10.44-h7634a1b_0.conda#b8f63aec37f31ffddac6dfdc0b31a73e
 https://conda.anaconda.org/conda-forge/osx-64/pixman-0.43.4-h73e2aa4_0.conda#cb134c1e03fd32f4e6bea3f6de2614fd
 https://conda.anaconda.org/conda-forge/osx-64/sigtool-0.1.3-h88f4db0_0.tar.bz2#fbfb84b9de9a6939cb165c02c69b1865
@@ -72,20 +72,20 @@ https://conda.anaconda.org/conda-forge/osx-64/libllvm18-18.1.8-h9ce406d_0.conda#
 https://conda.anaconda.org/conda-forge/osx-64/libtiff-4.6.0-h129831d_3.conda#568593071d2e6cea7b5fc1f75bfa10ca
 https://conda.anaconda.org/conda-forge/osx-64/mpfr-4.2.1-h4f6b447_1.conda#b90df08f0deb2f58631447c1462c92a7
 https://conda.anaconda.org/conda-forge/osx-64/python-3.12.4-h37a9e06_0_cpython.conda#94e2b77992f580ac6b7a4fc9b53018b3
-https://conda.anaconda.org/conda-forge/osx-64/quarto-1.4.550-h694c41f_1.conda#451204adcf15c8411d12ba240e7e979a
+https://conda.anaconda.org/conda-forge/osx-64/quarto-1.4.557-h694c41f_0.conda#6c89a6bf63516b38ad9cfc13c75c5676
 https://conda.anaconda.org/conda-forge/osx-64/tktable-2.10-hba9d6f1_6.conda#37fbdac8967151ada2e588cafd46b4b2
 https://conda.anaconda.org/conda-forge/noarch/argcomplete-3.4.0-pyhd8ed1ab_0.conda#9f736cae0da3365a4dbbfbadfac9f3a2
 https://conda.anaconda.org/conda-forge/osx-64/curl-8.8.0-hea67d85_1.conda#5c62b67625dffc2b592d8dd7d6493385
 https://conda.anaconda.org/conda-forge/osx-64/fontconfig-2.14.2-h5bb23bf_0.conda#86cc5867dfbee4178118392bae4a3c89
 https://conda.anaconda.org/conda-forge/osx-64/ld64_osx-64-711-had5d0d3_0.conda#cb63e1d1e11a1fffad54333330486ddd
 https://conda.anaconda.org/conda-forge/osx-64/libclang-cpp18.1-18.1.8-default_h0c94c6a_0.conda#8c5f33b247142ec0ec19931156a6c61d
-https://conda.anaconda.org/conda-forge/osx-64/libopenblas-0.3.27-openmp_hfef2a42_0.conda#00237c9c7f2cb6725fe2960680a6e225
+https://conda.anaconda.org/conda-forge/osx-64/libopenblas-0.3.27-openmp_h8869122_1.conda#c0798ad76ddd730dade6ff4dff66e0b5
 https://conda.anaconda.org/conda-forge/osx-64/llvm-tools-18.1.8-h9ce406d_0.conda#298da535b31f5eff3212c57ac7adc811
 https://conda.anaconda.org/conda-forge/osx-64/mpc-1.3.1-h81bd1dd_0.conda#c752c0eb6c250919559172c011e5f65b
 https://conda.anaconda.org/conda-forge/osx-64/pyyaml-6.0.1-py312h104f124_1.conda#260ed90aaf06061edabd7209638cf03b
-https://conda.anaconda.org/conda-forge/noarch/setuptools-70.1.1-pyhd8ed1ab_0.conda#985e9e86e1b0fc75a74a9bfab9309ef7
+https://conda.anaconda.org/conda-forge/noarch/setuptools-70.3.0-pyhd8ed1ab_0.conda#693bb57e8f92120caa956898065f3627
 https://conda.anaconda.org/conda-forge/noarch/toml-0.10.2-pyhd8ed1ab_0.tar.bz2#f832c45a477c78bebd107098db465095
-https://conda.anaconda.org/conda-forge/noarch/tomlkit-0.12.5-pyha770c72_0.conda#e5dde5caf905e9d95895e05f94967e14
+https://conda.anaconda.org/conda-forge/noarch/tomlkit-0.13.0-pyha770c72_0.conda#810ba6f354ddef812d0ddc4669cc8de6
 https://conda.anaconda.org/conda-forge/noarch/xmltodict-0.13.0-pyhd8ed1ab_0.tar.bz2#b5b33faed6ed2b4ba47a690b8f5c0818
 https://conda.anaconda.org/conda-forge/osx-64/cairo-1.18.0-h9f650ed_2.conda#d264e5b9759cab8d203cdfe43eabd8b5
 https://conda.anaconda.org/conda-forge/osx-64/cctools_osx-64-986-h58a35ae_0.conda#1139258589f2d752a578ed5b2680eb60
@@ -102,11 +102,11 @@ https://conda.anaconda.org/conda-forge/osx-64/gsl-2.7-h93259b0_0.tar.bz2#b4942b1
 https://conda.anaconda.org/conda-forge/osx-64/pango-1.54.0-h115fe74_1.conda#02bbb71305225106985ec1f28ff9f50b
 https://conda.anaconda.org/conda-forge/noarch/compiler-rt_osx-64-18.1.8-h7312ed1_0.conda#8b7c7465e63080455528944f4bc4f4dd
 https://conda.anaconda.org/conda-forge/osx-64/compiler-rt-18.1.8-h734a56e_0.conda#eb275c8bdae50bb82faa23437edf2b1d
-https://conda.anaconda.org/conda-forge/osx-64/clang_impl_osx-64-18.1.8-h6a44ed1_16.conda#ece76db937077c83cb0988ceb4e46f58
-https://conda.anaconda.org/conda-forge/osx-64/clang_osx-64-18.1.8-hb91bd55_16.conda#e70ba30a50acd4c05537f661ddb8bb6b
-https://conda.anaconda.org/conda-forge/osx-64/clangxx_impl_osx-64-18.1.8-h4b7810f_16.conda#3ee94ccf3eee97ab50d89022e5335f56
+https://conda.anaconda.org/conda-forge/osx-64/clang_impl_osx-64-18.1.8-h6a44ed1_17.conda#9f1d77447b08025b0cfef8828e1e1076
+https://conda.anaconda.org/conda-forge/osx-64/clang_osx-64-18.1.8-hb91bd55_17.conda#da0d5fa58ebc4edfcf9f2b55603bae97
+https://conda.anaconda.org/conda-forge/osx-64/clangxx_impl_osx-64-18.1.8-h4b7810f_17.conda#bb3d487d751348362ff8123cff494f98
 https://conda.anaconda.org/conda-forge/osx-64/gfortran_osx-64-12.3.0-h18f7dce_1.conda#436af2384c47aedb94af78a128e174f1
-https://conda.anaconda.org/conda-forge/osx-64/clangxx_osx-64-18.1.8-hb91bd55_16.conda#c276dac3c62c42f3e7c8c455e1a267a7
+https://conda.anaconda.org/conda-forge/osx-64/clangxx_osx-64-18.1.8-hb91bd55_17.conda#17076676b2ba0025dbecbac0e28becdd
 https://conda.anaconda.org/conda-forge/osx-64/r-base-4.3.3-h4648a1f_10.conda#c6c9589f19d40ad657894b43a02f8409
 https://conda.anaconda.org/bioconda/noarch/bioconductor-biocgenerics-0.48.1-r43hdfd78af_2.tar.bz2#a313dd8a932cfd178fad2f3e7e6a6184
 https://conda.anaconda.org/bioconda/noarch/bioconductor-data-packages-20231203-hdfd78af_0.tar.bz2#797a95b275a72d48553852e7845edf19
@@ -152,7 +152,7 @@ https://conda.anaconda.org/conda-forge/noarch/r-labeling-0.4.3-r43hc72bb7e_1.con
 https://conda.anaconda.org/conda-forge/osx-64/r-lattice-0.22_6-r43h6b9d099_1.conda#238e56af678fe826dfcf8ab0cbb04bbe
 https://conda.anaconda.org/conda-forge/osx-64/r-lazyeval-0.2.2-r43h6b9d099_5.conda#e94061da461830f0ebce000f0997053e
 https://conda.anaconda.org/conda-forge/noarch/r-listenv-0.9.1-r43hc72bb7e_1.conda#ec5e5ed484ed53445c5ae5debc3f3f53
-https://conda.anaconda.org/conda-forge/osx-64/r-log4r-0.4.3-r43h6dc245f_1.conda#91483f8222f1f7677ef4603d94dbd909
+https://conda.anaconda.org/conda-forge/osx-64/r-log4r-0.4.3-r43h6b9d099_2.conda#8729171427cbba0ff4d5ee3a6373e7cb
 https://conda.anaconda.org/conda-forge/osx-64/r-lpsolve-5.6.20-r43h6b9d099_1.conda#7462b6a7aee0fa4281e0d77c78296689
 https://conda.anaconda.org/conda-forge/osx-64/r-magrittr-2.0.3-r43h6b9d099_3.conda#9c935948961f583ba8150f483c635fd5
 https://conda.anaconda.org/conda-forge/osx-64/r-mass-7.3_60.0.1-r43h6b9d099_1.conda#08f31cbc14fdbb61c8419e2faa257535
@@ -184,7 +184,7 @@ https://conda.anaconda.org/conda-forge/noarch/r-shape-1.4.6.1-r43ha770c72_1.cond
 https://conda.anaconda.org/conda-forge/noarch/r-snow-0.4_4-r43hc72bb7e_3.conda#60eeeef67921f38a80c1778eae3bbbb9
 https://conda.anaconda.org/conda-forge/osx-64/r-sourcetools-0.1.7_1-r43h25d921d_2.conda#a967935d708dfab75755cf4dc7dd4907
 https://conda.anaconda.org/conda-forge/noarch/r-squarem-2021.1-r43hc72bb7e_3.conda#7540130cd26e12a02742dac9ddc184d6
-https://conda.anaconda.org/conda-forge/osx-64/r-stringi-1.8.4-r43ha6447fb_1.conda#19218bb400e94fa3f4d3be49dec37b0e
+https://conda.anaconda.org/conda-forge/osx-64/r-stringi-1.8.4-r43ha6447fb_2.conda#7613ebe60a1d07bde647c39c917b5487
 https://conda.anaconda.org/conda-forge/osx-64/r-sys-3.4.2-r43h6b9d099_2.conda#169f27d27ea7742ba861b51ebd50d0f9
 https://conda.anaconda.org/conda-forge/noarch/r-timedate-4032.109-r43hc72bb7e_1.conda#0e901aea4b8040ddf8b0a612fc283407
 https://conda.anaconda.org/conda-forge/osx-64/r-utf8-1.2.4-r43h6b9d099_1.conda#b08ffc8e28c8532268df1b26b27aa5a1
@@ -200,7 +200,7 @@ https://conda.anaconda.org/bioconda/noarch/bioconductor-genomeinfodbdata-1.2.11-
 https://conda.anaconda.org/bioconda/noarch/bioconductor-matrixgenerics-1.14.0-r43hdfd78af_3.tar.bz2#c79f36cc0cd464874aefd50a700d0079
 https://conda.anaconda.org/bioconda/osx-64/bioconductor-rhtslib-2.4.0-r43h4c50009_2.tar.bz2#87acafb6a63e0426c27c759ba2dc097b
 https://conda.anaconda.org/bioconda/osx-64/bioconductor-s4vectors-0.40.2-r43h4c50009_2.tar.bz2#935e0479f88ba1893d264e95ff235b27
-https://conda.anaconda.org/conda-forge/noarch/r-argparse-2.2.3-r43hc72bb7e_0.conda#48ca12b4fb578b31e020d1d657f26354
+https://conda.anaconda.org/conda-forge/noarch/r-argparse-2.2.3-r43hc72bb7e_1.conda#4a112f5abf0991d2f72d0efc7abbfc04
 https://conda.anaconda.org/conda-forge/osx-64/r-askpass-1.2.0-r43h6b9d099_1.conda#8fbf76cdd3895094a70c893da67bd358
 https://conda.anaconda.org/conda-forge/noarch/r-assertable-0.2.8-r43hc72bb7e_2.conda#36f455211da59b0f91b9907f31c3cf96
 https://conda.anaconda.org/conda-forge/noarch/r-bibtex-0.5.1-r43hc72bb7e_2.conda#4514eabc038859b5ae5e119208b23f6d
@@ -217,18 +217,18 @@ https://conda.anaconda.org/conda-forge/noarch/r-lambda.r-1.2.4-r43hc72bb7e_4.con
 https://conda.anaconda.org/conda-forge/osx-64/r-later-1.3.2-r43h25d921d_1.conda#57e123262112496c4818103e8221e656
 https://conda.anaconda.org/conda-forge/noarch/r-lifecycle-1.0.4-r43hc72bb7e_0.conda#291d2fb68ea1b181644b40d6743ae000
 https://conda.anaconda.org/conda-forge/osx-64/r-limsolve-1.5.7.1-r43h9612530_1.conda#a7e23384461c4d22774fa03a6c806899
-https://conda.anaconda.org/conda-forge/osx-64/r-matrix-1.6_5-r43h39411cf_0.conda#fd1e60a0d877cabb897fd074e60dd858
+https://conda.anaconda.org/conda-forge/osx-64/r-matrix-1.6_5-r43h9cf22e7_1.conda#54862e354e1f93bf27959f58040624a9
 https://conda.anaconda.org/conda-forge/osx-64/r-modelmetrics-1.2.2.2-r43hccecf6d_3.conda#57ec9b0d52d734adecc13f3ebd2187e2
 https://conda.anaconda.org/conda-forge/noarch/r-munsell-0.5.1-r43hc72bb7e_1.conda#8b2f9bb8064ae0896ffedd984661a2d5
 https://conda.anaconda.org/conda-forge/osx-64/r-nlme-3.1_165-r43h9612530_1.conda#388675d1728055c4ce9c4c4a57859206
 https://conda.anaconda.org/conda-forge/osx-64/r-nnet-7.3_19-r43h6b9d099_2.conda#517120637781ce2012096bf0fe490a7a
-https://conda.anaconda.org/conda-forge/osx-64/r-openxlsx2-1.8-r43h25d921d_0.conda#9f2eb6d11488bc91c0c9ce5d54ca96f2
+https://conda.anaconda.org/conda-forge/osx-64/r-openxlsx2-1.8-r43h25d921d_1.conda#b3d420fde0641383ae7cfec54b609952
 https://conda.anaconda.org/conda-forge/osx-64/r-pki-0.1_14-r43h6b9d099_0.conda#a1afcce33d61942e16c5f418a566d727
 https://conda.anaconda.org/conda-forge/osx-64/r-plyr-1.8.9-r43h25d921d_1.conda#1ca3bad195633deed13c8cd8bfd4852e
 https://conda.anaconda.org/conda-forge/noarch/r-prettyunits-1.2.0-r43hc72bb7e_1.conda#cf655364ee1c16ad385e829987a67458
 https://conda.anaconda.org/conda-forge/osx-64/r-processx-3.8.4-r43h6b9d099_1.conda#d6051f70994a2724ddfa695cea4e7a05
 https://conda.anaconda.org/conda-forge/noarch/r-progressr-0.14.0-r43hc72bb7e_1.conda#ce5d69c0d781106778e951b44313404d
-https://conda.anaconda.org/conda-forge/osx-64/r-rcurl-1.98_1.14-r43hbd64cb6_0.conda#69424eec97996e9b640ee73d1bcc30e4
+https://conda.anaconda.org/conda-forge/osx-64/r-rcurl-1.98_1.16-r43he8ffcfd_0.conda#355803653df4084dda31bb660a0dfb02
 https://conda.anaconda.org/conda-forge/osx-64/r-timechange-0.3.0-r43h25d921d_1.conda#51c015491614a690d8809baf3d49b3f0
 https://conda.anaconda.org/conda-forge/noarch/r-tinytex-0.51-r43hc72bb7e_1.conda#35ba2dc42178aa25fcf020aa39491d0e
 https://conda.anaconda.org/conda-forge/osx-64/r-tzdb-0.4.0-r43h25d921d_2.conda#f8ce491c4ae680522fa98d6a5e8be407
@@ -236,21 +236,21 @@ https://conda.anaconda.org/conda-forge/osx-64/r-xml2-1.3.6-r43h3031e3b_1.conda#2
 https://conda.anaconda.org/bioconda/noarch/bioconductor-biocio-1.12.0-r43hdfd78af_0.tar.bz2#bff7970f9c895f54216ca423a271e3dc
 https://conda.anaconda.org/bioconda/osx-64/bioconductor-iranges-2.36.0-r43h4c50009_2.tar.bz2#32daa8972d493afca2f7b7e7311e99b3
 https://conda.anaconda.org/conda-forge/noarch/r-doparallel-1.0.17-r43hc72bb7e_3.conda#4206403c7e833e5c4eaa75c7d110ca2a
-https://conda.anaconda.org/conda-forge/osx-64/r-e1071-1.7_14-r43h64b2c41_0.conda#f225b63c74c3e7e10dfc094520fa6b91
+https://conda.anaconda.org/conda-forge/osx-64/r-e1071-1.7_14-r43h25d921d_1.conda#91b7e85e0d1250ecdf586aed1341d360
 https://conda.anaconda.org/conda-forge/noarch/r-futile.logger-1.4.3-r43hc72bb7e_1006.conda#dbfd04b54b6ac781070393f2184b3c6d
 https://conda.anaconda.org/conda-forge/noarch/r-future-1.33.2-r43h785f33e_1.conda#dd5dbf92b6b19e4261fb34299c4475c5
 https://conda.anaconda.org/conda-forge/noarch/r-gtable-0.3.5-r43hc72bb7e_0.conda#4afa6b3bc18ef585bac26420528ed1de
 https://conda.anaconda.org/conda-forge/osx-64/r-htmltools-0.5.8.1-r43h25d921d_1.conda#33af1cfe705e1c51f76325dd1fae552b
-https://conda.anaconda.org/conda-forge/noarch/r-knitr-1.47-r43hc72bb7e_1.conda#967490c6696683f4e6f257ea1a1ece49
+https://conda.anaconda.org/conda-forge/noarch/r-knitr-1.48-r43hc72bb7e_0.conda#78b89f7a7df2bacfa367589fc95a36db
 https://conda.anaconda.org/conda-forge/osx-64/r-lubridate-1.9.3-r43h6dc245f_0.conda#ca8d466be4a8903ff8143fac3abf11b7
 https://conda.anaconda.org/conda-forge/noarch/r-memoise-2.0.1-r43hc72bb7e_3.conda#98e3d2eb6635a5f7b8af487f47184a98
-https://conda.anaconda.org/conda-forge/osx-64/r-mgcv-1.9_1-r43hc8b66e8_0.conda#c662b9254c9781f8ccf0f423480de904
+https://conda.anaconda.org/conda-forge/osx-64/r-mgcv-1.9_1-r43h374a70c_1.conda#aa498fa8c1b485ac3df32ca44f05be95
 https://conda.anaconda.org/conda-forge/osx-64/r-openssl-2.2.0-r43hc743e98_0.conda#c8ede66f1f371ef42372dc3c152ee89e
 https://conda.anaconda.org/conda-forge/osx-64/r-proc-1.18.5-r43h25d921d_1.conda#365a839e0391fb9626ee2b51893b33ac
 https://conda.anaconda.org/conda-forge/osx-64/r-promises-1.3.0-r43h25d921d_1.conda#f8dfeee3d88623cbd44a78e574e00e92
 https://conda.anaconda.org/bioconda/osx-64/r-restfulr-0.0.15-r43hfa19939_4.tar.bz2#96ae8ec5e1d54d94623eb63c08b0d370
 https://conda.anaconda.org/conda-forge/noarch/r-scales-1.3.0-r43hc72bb7e_0.conda#508360956e18c2b0cc18968cdb786c78
-https://conda.anaconda.org/conda-forge/osx-64/r-survival-3.7_0-r43h6b9d099_0.conda#630192fb86457cf87349601526026874
+https://conda.anaconda.org/conda-forge/osx-64/r-survival-3.7_0-r43h6b9d099_1.conda#73681c40f9c24ca88a3c73a71cc2911e
 https://conda.anaconda.org/conda-forge/osx-64/r-vctrs-0.6.5-r43h64b2c41_0.conda#25482b91bd4432bacec335027457c3d1
 https://conda.anaconda.org/bioconda/osx-64/bioconductor-biocparallel-1.36.0-r43hc0ef7c4_2.tar.bz2#79ac73ccaf0ed62ba62fa965a2682f28
 https://conda.anaconda.org/bioconda/noarch/bioconductor-genomeinfodb-1.38.1-r43hdfd78af_1.tar.bz2#03e20a01b672b693c9470dec80d83993
@@ -275,7 +275,7 @@ https://conda.anaconda.org/bioconda/osx-64/bioconductor-biostrings-2.70.1-r43h4c
 https://conda.anaconda.org/bioconda/osx-64/bioconductor-genomicranges-1.54.1-r43h4c50009_2.tar.bz2#9b2c85bd7bbf93a76f692f51e7a4f197
 https://conda.anaconda.org/bioconda/osx-64/bioconductor-sparsearray-1.2.2-r43h4c50009_2.tar.bz2#26722d12493c5b93ba4216b2dc29f770
 https://conda.anaconda.org/conda-forge/noarch/r-bslib-0.7.0-r43hc72bb7e_0.conda#6e2bfdc782284259390d09bb083142b2
-https://conda.anaconda.org/conda-forge/noarch/r-lava-1.7.3-r43hc72bb7e_0.conda#813b11bcb3baa5bac2ff27b63b94a0b2
+https://conda.anaconda.org/conda-forge/noarch/r-lava-1.7.3-r43hc72bb7e_1.conda#3d13916ab4fa9a82daaf27db47ced7a0
 https://conda.anaconda.org/conda-forge/noarch/r-pkgmaker-0.32.10-r43hc72bb7e_1.conda#ecc7c90afc8ae9f8725550acdb5454f9
 https://conda.anaconda.org/conda-forge/noarch/r-progress-1.2.3-r43hc72bb7e_0.conda#49c52ccafe27439ac6b69a74c626b3a8
 https://conda.anaconda.org/conda-forge/osx-64/r-reshape2-1.4.4-r43hac7d2d5_3.conda#5a63ed2d1a50945e54152623f595881b
@@ -320,5 +320,5 @@ https://conda.anaconda.org/bioconda/noarch/bioconductor-bsgenome.hsapiens.ucsc.h
 https://conda.anaconda.org/bioconda/noarch/bioconductor-genomicfeatures-1.54.1-r43hdfd78af_0.tar.bz2#445ea419486180673fffc192b5fe8edb
 https://conda.anaconda.org/bioconda/osx-64/bioconductor-variantannotation-1.48.1-r43h4c50009_1.tar.bz2#4bc1f791804daa0570cd35a63ca0a268
 https://conda.anaconda.org/bioconda/noarch/bioconductor-mutationalpatterns-3.12.0-r43hdfd78af_0.tar.bz2#d22030798f7d464ddb092e4651625210
-https://conda.anaconda.org/pcgr/noarch/r-pcgrr-2.0.1-r43_0.tar.bz2#d5c0015b573b871d6bd4375c20f101f8
+https://conda.anaconda.org/pcgr/noarch/r-pcgrr-2.0.2-r43_0.tar.bz2#7bacc2ff007b4004ca32e4b594d21e58
 https://conda.anaconda.org/pcgr/noarch/r-cpsr-2.0.1-r43_0.tar.bz2#5bab752f34e3e1d91e0225cf7a4a8251