diff --git a/docs/docs/configuration/mapper.mdx b/docs/docs/configuration/mapper.mdx
index 558a7bb485..9bd84445aa 100644
--- a/docs/docs/configuration/mapper.mdx
+++ b/docs/docs/configuration/mapper.mdx
@@ -68,6 +68,32 @@ public partial class CarMapper
 }
 ```
 
+#### Ignore a memeber at definition
+
+To ignore a property or field at definition, the `MapperIgnoreAttribute` can be used.
+
+```csharp
+public partial class CarMapper
+{
+    public partial CarDto ToDto(Car car);
+}
+
+public class Car
+{
+    // highlight-start
+    [MapperIgnore]
+    // highlight-end
+    public int Id { get; set; }
+
+    public string ModelName { get; set; }
+}
+
+public class CarDto
+{
+    public string ModelName { get; set; }
+}
+```
+
 #### Ignore obsolete members
 
 By default, Mapperly will map source/target members marked with `ObsoleteAttribute`.
diff --git a/src/Riok.Mapperly.Abstractions/MapperIgnoreAttribute.cs b/src/Riok.Mapperly.Abstractions/MapperIgnoreAttribute.cs
new file mode 100644
index 0000000000..2834cedbb7
--- /dev/null
+++ b/src/Riok.Mapperly.Abstractions/MapperIgnoreAttribute.cs
@@ -0,0 +1,10 @@
+using System.Diagnostics;
+
+namespace Riok.Mapperly.Abstractions;
+
+/// <summary>
+/// Ignores a member from the mapping.
+/// </summary>
+[AttributeUsage(AttributeTargets.Property | AttributeTargets.Field)]
+[Conditional("MAPPERLY_ABSTRACTIONS_SCOPE_RUNTIME")]
+public sealed class MapperIgnoreAttribute : Attribute;
diff --git a/src/Riok.Mapperly.Abstractions/PublicAPI.Shipped.txt b/src/Riok.Mapperly.Abstractions/PublicAPI.Shipped.txt
index bca69e392d..f1caebc197 100644
--- a/src/Riok.Mapperly.Abstractions/PublicAPI.Shipped.txt
+++ b/src/Riok.Mapperly.Abstractions/PublicAPI.Shipped.txt
@@ -42,6 +42,8 @@ Riok.Mapperly.Abstractions.MapperConstructorAttribute.MapperConstructorAttribute
 Riok.Mapperly.Abstractions.MapperIgnoreObsoleteMembersAttribute
 Riok.Mapperly.Abstractions.MapperIgnoreObsoleteMembersAttribute.IgnoreObsoleteStrategy.get -> Riok.Mapperly.Abstractions.IgnoreObsoleteMembersStrategy
 Riok.Mapperly.Abstractions.MapperIgnoreObsoleteMembersAttribute.MapperIgnoreObsoleteMembersAttribute(Riok.Mapperly.Abstractions.IgnoreObsoleteMembersStrategy ignoreObsoleteStrategy = (Riok.Mapperly.Abstractions.IgnoreObsoleteMembersStrategy)-1) -> void
+Riok.Mapperly.Abstractions.MapperIgnoreAttribute
+Riok.Mapperly.Abstractions.MapperIgnoreAttribute.MapperIgnoreAttribute() -> void
 Riok.Mapperly.Abstractions.MapperIgnoreSourceAttribute
 Riok.Mapperly.Abstractions.MapperIgnoreSourceAttribute.MapperIgnoreSourceAttribute(string! source) -> void
 Riok.Mapperly.Abstractions.MapperIgnoreSourceAttribute.Source.get -> string!
diff --git a/src/Riok.Mapperly/Descriptors/MappingBodyBuilders/BuilderContext/MembersMappingBuilderContext.cs b/src/Riok.Mapperly/Descriptors/MappingBodyBuilders/BuilderContext/MembersMappingBuilderContext.cs
index 643e6c4dbf..b05e50da51 100644
--- a/src/Riok.Mapperly/Descriptors/MappingBodyBuilders/BuilderContext/MembersMappingBuilderContext.cs
+++ b/src/Riok.Mapperly/Descriptors/MappingBodyBuilders/BuilderContext/MembersMappingBuilderContext.cs
@@ -34,10 +34,12 @@ protected MembersMappingBuilderContext(MappingBuilderContext builderContext, T m
         TargetMembers = GetTargetMembers();
 
         IgnoredSourceMemberNames = builderContext
-            .Configuration.Members.IgnoredSources.Concat(GetIgnoredObsoleteSourceMembers())
+            .Configuration.Members.IgnoredSources.Concat(GetIgnoredSourceMembers())
+            .Concat(GetIgnoredObsoleteSourceMembers())
             .ToHashSet();
         var ignoredTargetMemberNames = builderContext
-            .Configuration.Members.IgnoredTargets.Concat(GetIgnoredObsoleteTargetMembers())
+            .Configuration.Members.IgnoredTargets.Concat(GetIgnoredTargetMembers())
+            .Concat(GetIgnoredObsoleteTargetMembers())
             .ToHashSet();
 
         _ignoredUnmatchedSourceMemberNames = InitIgnoredUnmatchedProperties(IgnoredSourceMemberNames, _unmappedSourceMemberNames);
@@ -143,6 +145,22 @@ private IEnumerable<string> GetIgnoredObsoleteSourceMembers()
             .Select(x => x.Name);
     }
 
+    private IEnumerable<string> GetIgnoredTargetMembers()
+    {
+        return BuilderContext
+            .SymbolAccessor.GetAllAccessibleMappableMembers(Mapping.TargetType)
+            .Where(x => BuilderContext.SymbolAccessor.HasAttribute<MapperIgnoreAttribute>(x.MemberSymbol))
+            .Select(x => x.Name);
+    }
+
+    private IEnumerable<string> GetIgnoredSourceMembers()
+    {
+        return BuilderContext
+            .SymbolAccessor.GetAllAccessibleMappableMembers(Mapping.SourceType)
+            .Where(x => BuilderContext.SymbolAccessor.HasAttribute<MapperIgnoreAttribute>(x.MemberSymbol))
+            .Select(x => x.Name);
+    }
+
     private HashSet<string> GetSourceMemberNames()
     {
         return BuilderContext.SymbolAccessor.GetAllAccessibleMappableMembers(Mapping.SourceType).Select(x => x.Name).ToHashSet();
diff --git a/test/Riok.Mapperly.IntegrationTests/Dto/TestObjectDto.cs b/test/Riok.Mapperly.IntegrationTests/Dto/TestObjectDto.cs
index 7a391aa5fc..a92c8d2a07 100644
--- a/test/Riok.Mapperly.IntegrationTests/Dto/TestObjectDto.cs
+++ b/test/Riok.Mapperly.IntegrationTests/Dto/TestObjectDto.cs
@@ -1,6 +1,7 @@
 using System;
 using System.Collections.Generic;
 using System.Collections.Immutable;
+using Riok.Mapperly.Abstractions;
 using Riok.Mapperly.IntegrationTests.Models;
 
 namespace Riok.Mapperly.IntegrationTests.Dto
@@ -119,6 +120,9 @@ public TestObjectDto(int ctorValue, int unknownValue = 10, int ctorValue2 = 100)
         [Obsolete]
         public int IgnoredObsoleteValue { get; set; }
 
+        [MapperIgnore]
+        public int IgnoredMemberValue { get; set; }
+
         public DateOnly DateTimeValueTargetDateOnly { get; set; }
 
         public TimeOnly DateTimeValueTargetTimeOnly { get; set; }
diff --git a/test/Riok.Mapperly.Tests/Mapping/IgnoreAttributeTest.cs b/test/Riok.Mapperly.Tests/Mapping/IgnoreAttributeTest.cs
new file mode 100644
index 0000000000..a47e61d79f
--- /dev/null
+++ b/test/Riok.Mapperly.Tests/Mapping/IgnoreAttributeTest.cs
@@ -0,0 +1,82 @@
+using Riok.Mapperly.Diagnostics;
+
+namespace Riok.Mapperly.Tests.Mapping;
+
+[UsesVerify]
+public class IgnoreAttributeTest
+{
+    private readonly string _classA = TestSourceBuilder.CSharp(
+        """
+        class A
+        {
+            public int Value { get; set; }
+
+            [MapperIgnore]
+            public int Ignored { get; set; }
+        }
+        """
+    );
+
+    private readonly string _classB = TestSourceBuilder.CSharp(
+        """
+        class B
+        {
+            public int Value { get; set; }
+
+            [MapperIgnore]
+            public int Ignored { get; set; }
+        }
+        """
+    );
+
+    [Fact]
+    public void ClassAttributeIgnoreMember()
+    {
+        var source = TestSourceBuilder.Mapping("A", "B", TestSourceBuilderOptions.Default, _classA, _classB);
+
+        TestHelper
+            .GenerateMapper(source)
+            .Should()
+            .HaveSingleMethodBody(
+                """
+                var target = new global::B();
+                target.Value = source.Value;
+                return target;
+                """
+            );
+    }
+
+    [Fact]
+    public void MapPropertyOverridesIgnoreMember()
+    {
+        var source = TestSourceBuilder.MapperWithBodyAndTypes(
+            """
+            [MapProperty("Ignored", "Ignored")]
+            partial B Map(A source);
+            """,
+            _classA,
+            _classB
+        );
+
+        TestHelper
+            .GenerateMapper(source, TestHelperOptions.AllowDiagnostics)
+            .Should()
+            .HaveSingleMethodBody(
+                """
+                var target = new global::B();
+                target.Value = source.Value;
+                target.Ignored = source.Ignored;
+                return target;
+                """
+            )
+            .HaveDiagnostic(
+                DiagnosticDescriptors.IgnoredSourceMemberExplicitlyMapped,
+                "The source member Ignored on A is ignored, but is also mapped by the MapPropertyAttribute"
+            )
+            .HaveDiagnostic(
+                DiagnosticDescriptors.IgnoredTargetMemberExplicitlyMapped,
+                "The target member Ignored on B is ignored, but is also mapped by the MapPropertyAttribute"
+            )
+            .HaveAssertedAllDiagnostics();
+    }
+}