README.Rmd

---
output: github_document
---
<!-- markdownlint-disable-file -->
<!-- README.md needs to be generated from README.Rmd. Please edit that file -->

# RobinCar2

```{r, echo = FALSE}
knitr::opts_chunk$set(
  collapse = TRUE,
  comment = "#>",
  fig.path = "README-"
)
```

<!-- badges: start -->
[![Project Status: Active – The project has reached a stable, usable state and is being actively developed.](https://www.repostatus.org/badges/latest/active.svg)](https://www.repostatus.org/#active)
[![CRAN status](https://www.r-pkg.org/badges/version-last-release/RobinCar2)](https://www.r-pkg.org/badges/version-last-release/RobinCar2)
[![CRAN monthly downloads](https://cranlogs.r-pkg.org/badges/RobinCar2)](https://cranlogs.r-pkg.org/badges/RobinCar2)
[![CRAN total downloads](https://cranlogs.r-pkg.org/badges/grand-total/RobinCar2)](https://cranlogs.r-pkg.org/badges/grand-total/RobinCar2)
[![Code Coverage](https://raw.githubusercontent.com/openpharma/RobinCar2/_xml_coverage_reports/data/main/badge.svg)](https://raw.githubusercontent.com/openpharma/RobinCar2/_xml_coverage_reports/data/main/coverage.xml)
<!-- badges: end -->
\

RobinCar2 is a package to provide robust inference of covariate adjusted analysis under stratified randomization.
The methods implemented are recommended by [FDA guidance on covariate adjustment](https://www.fda.gov/regulatory-information/search-fda-guidance-documents/adjusting-covariates-randomized-clinical-trials-drugs-and-biological-products).
The methods are based on the work of [Ye, Shao, Yi and Zhao (2023)](doi:10.1080/01621459.2022.2049278),
[Ye, Bannick, Yi and Shao (2023)](doi:10.1080/24754269.2023.2205802), 
[Ye, Shao, Yi (2023)](doi:10.1093/biomet/asad045>) and
[Bannick, Shao, Liu, Du, Yi, Ye (2024)](doi:10.48550/arXiv.2306.10213).

## Installation

### Development

You can install the current development version from `github` with:

```{r gh-installation, eval = FALSE}
if (!require("remotes")) {
  install.packages("remotes")
}

remotes::install_github(
  "openpharma/RobinCar2"
)
```

## Citing `RobinCar2`

To cite `RobinCar2` please see [here](https://openpharma.github.io/RobinCar2/main/authors.html#citation).