diff --git a/requirements/constraints.txt b/requirements/constraints.txt
index 204d2376ee32..caa6483f0623 100644
--- a/requirements/constraints.txt
+++ b/requirements/constraints.txt
@@ -119,6 +119,11 @@ openai<=0.28.1
 # https://github.com/openedx/edx-platform/issues/34103
 optimizely-sdk<5.0
 
+# lxml>=5.0 introduced breaking changes related to system dependencies
+# lxml==5.2.1 introduced new extra so we'll nee to rename lxml --> lxml[html-clean] 
+# This constraint can be removed once we upgrade to Python 3.11
+lxml<5.0
+
 # xmlsec==1.3.14 breaking tests for all builds, can be removed once a fix is available
 xmlsec<1.3.14
 
diff --git a/requirements/edx-sandbox/base.txt b/requirements/edx-sandbox/base.txt
index ac73dc3fcad6..53c796077848 100644
--- a/requirements/edx-sandbox/base.txt
+++ b/requirements/edx-sandbox/base.txt
@@ -30,8 +30,9 @@ joblib==1.3.2
     # via nltk
 kiwisolver==1.4.5
     # via matplotlib
-lxml==5.2.1
+lxml==4.9.4
     # via
+    #   -c requirements/edx-sandbox/../constraints.txt
     #   -r requirements/edx-sandbox/base.in
     #   openedx-calc
 markupsafe==2.1.5
diff --git a/requirements/edx/base.txt b/requirements/edx/base.txt
index 3c69a49a6655..81a3ff030dec 100644
--- a/requirements/edx/base.txt
+++ b/requirements/edx/base.txt
@@ -682,6 +682,7 @@ lti-consumer-xblock==9.10.0
     # via -r requirements/edx/kernel.in
 lxml==4.9.4
     # via
+    #   -c requirements/edx/../constraints.txt
     #   -r requirements/edx/kernel.in
     #   edx-i18n-tools
     #   edxval
diff --git a/requirements/edx/development.txt b/requirements/edx/development.txt
index 5682263d5b7b..271b69c7876a 100644
--- a/requirements/edx/development.txt
+++ b/requirements/edx/development.txt
@@ -1135,6 +1135,7 @@ lti-consumer-xblock==9.10.0
     #   -r requirements/edx/testing.txt
 lxml==4.9.4
     # via
+    #   -c requirements/edx/../constraints.txt
     #   -r requirements/edx/doc.txt
     #   -r requirements/edx/testing.txt
     #   edx-i18n-tools
diff --git a/requirements/edx/doc.txt b/requirements/edx/doc.txt
index ea2c1e8f7c6c..26e9ff1ed00b 100644
--- a/requirements/edx/doc.txt
+++ b/requirements/edx/doc.txt
@@ -805,6 +805,7 @@ lti-consumer-xblock==9.10.0
     # via -r requirements/edx/base.txt
 lxml==4.9.4
     # via
+    #   -c requirements/edx/../constraints.txt
     #   -r requirements/edx/base.txt
     #   edx-i18n-tools
     #   edxval
diff --git a/requirements/edx/testing.txt b/requirements/edx/testing.txt
index ed076477d1a1..2ce58823e378 100644
--- a/requirements/edx/testing.txt
+++ b/requirements/edx/testing.txt
@@ -858,6 +858,7 @@ lti-consumer-xblock==9.10.0
     # via -r requirements/edx/base.txt
 lxml==4.9.4
     # via
+    #   -c requirements/edx/../constraints.txt
     #   -r requirements/edx/base.txt
     #   edx-i18n-tools
     #   edxval
diff --git a/scripts/user_retirement/requirements/base.txt b/scripts/user_retirement/requirements/base.txt
index 1adc428d5afa..f66759b556fa 100644
--- a/scripts/user_retirement/requirements/base.txt
+++ b/scripts/user_retirement/requirements/base.txt
@@ -86,7 +86,9 @@ jmespath==1.0.1
     #   boto3
     #   botocore
 lxml==4.9.3
-    # via zeep
+    # via
+    #   -c scripts/user_retirement/requirements/../../../requirements/constraints.txt
+    #   zeep
 more-itertools==10.2.0
     # via simple-salesforce
 newrelic==9.5.0