diff --git a/.readthedocs.yml b/.readthedocs.yml
index 2a3c920b45..dcf3204080 100644
--- a/.readthedocs.yml
+++ b/.readthedocs.yml
@@ -12,4 +12,4 @@ build:
 
 python:
   install:
-    - requirements: docs-requirements.txt
+    - requirements: rtd-requirements.txt
diff --git a/CHANGELOG.md b/CHANGELOG.md
index a23f7fe2d0..1aeccfb60c 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -48,6 +48,8 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
   ([#3022](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3022))
 - Replace all instrumentor unit test `assertEqualSpanInstrumentationInfo` calls with `assertEqualSpanInstrumentationScope` calls
   ([#3037](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3037))
+- `opentelemetry-instrumentation-sqlalchemy` Fixes engines from `sqlalchemy.engine_from_config` not being fully instrumented
+  ([#2816](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/2816))
 - `opentelemetry-instrumentation-sqlalchemy`: Fix a remaining memory leak in EngineTracer
   ([#3053](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3053))
 
diff --git a/CONTRIBUTING.md b/CONTRIBUTING.md
index 633a356c40..e90402edc2 100644
--- a/CONTRIBUTING.md
+++ b/CONTRIBUTING.md
@@ -272,7 +272,11 @@ Below is a checklist of things to be mindful of when implementing a new instrume
 - Isolate sync and async test
   - For synchronous tests, the typical test case class is inherited from `opentelemetry.test.test_base.TestBase`. However, if you want to write asynchronous tests, the test case class should inherit also from `IsolatedAsyncioTestCase`. Adding asynchronous tests to a common test class can lead to tests passing without actually running, which can be misleading.
   - ex. <https://github.com/open-telemetry/opentelemetry-python-contrib/blob/60fb936b7e5371b3e5587074906c49fb873cbd76/instrumentation/opentelemetry-instrumentation-grpc/tests/test_aio_server_interceptor.py#L84>
-- All instrumentations have the same version. If you are going to develop a new instrumentation it would probably have `X.Y.dev` version and depends on `opentelemetry-instrumentation` and `opentelemetry-semantic-conventions` for the same version. That means that if you want to install your instrumentation you need to install its dependencies from this repo and the core repo also from git.
+- Most of the instrumentations have the same version. If you are going to develop a new instrumentation it would probably have `X.Y.dev` version and depends on `opentelemetry-instrumentation` and `opentelemetry-semantic-conventions` for a [compatible version](https://peps.python.org/pep-0440/#compatible-release). That means that you may need to install the instrumentation dependencies from this repo and the core repo from git.
+- Documentation
+  - When adding a new instrumentation remember to add an entry in `docs/instrumentation/` named `<instrumentation>/<instrumentation>.rst` to have the instrumentation documentation referenced from the index. You can use the entry template available [here](./_template/autodoc_entry.rst)
+- Testing
+  - When adding a new instrumentation remember to update `tox.ini` adding appropriate rules in `envlist`, `command_pre` and `commands` sections
 
 ## Guideline for GenAI instrumentations
 
diff --git a/_template/autodoc_entry.rst b/_template/autodoc_entry.rst
new file mode 100644
index 0000000000..ee2688bacd
--- /dev/null
+++ b/_template/autodoc_entry.rst
@@ -0,0 +1,7 @@
+.. include:: ../../../instrumentation/opentelemetry-instrumentation-<REPLACE ME>/README.rst
+    :end-before: References
+
+.. automodule:: opentelemetry.instrumentation.<REPLACE ME>
+    :members:
+    :undoc-members:
+    :show-inheritance:
diff --git a/docs-requirements.txt b/docs-requirements.txt
index 43e2265f7c..d547e806a3 100644
--- a/docs-requirements.txt
+++ b/docs-requirements.txt
@@ -2,14 +2,6 @@ sphinx==7.1.2
 sphinx-rtd-theme==2.0.0rc4
 sphinx-autodoc-typehints==1.25.2
 
-# Need to install the api/sdk in the venv for autodoc. Modifying sys.path
-# doesn't work for pkg_resources.
--e "git+https://github.com/open-telemetry/opentelemetry-python.git#egg=opentelemetry-api&subdirectory=opentelemetry-api"
--e "git+https://github.com/open-telemetry/opentelemetry-python.git#egg=opentelemetry-semantic-conventions&subdirectory=opentelemetry-semantic-conventions"
--e "git+https://github.com/open-telemetry/opentelemetry-python.git#egg=opentelemetry-sdk&subdirectory=opentelemetry-sdk"
--e "git+https://github.com/open-telemetry/opentelemetry-python-contrib.git#egg=opentelemetry-util-http&subdirectory=util/opentelemetry-util-http"
-./opentelemetry-instrumentation
-
 # Required by opentelemetry-instrumentation
 fastapi>=0.65.2
 pymemcache~=1.3
diff --git a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/CHANGELOG.md b/instrumentation-genai/opentelemetry-instrumentation-openai-v2/CHANGELOG.md
index 2c10498511..4644ee3dc5 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/CHANGELOG.md
+++ b/instrumentation-genai/opentelemetry-instrumentation-openai-v2/CHANGELOG.md
@@ -7,6 +7,8 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 
 ## Unreleased
 
+- Coerce openai response_format to semconv format
+  ([#3073](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3073))
 - Add example to `opentelemetry-instrumentation-openai-v2`
   ([#3006](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3006))
 - Support for `AsyncOpenAI/AsyncCompletions` ([#2984](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/2984))
diff --git a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/src/opentelemetry/instrumentation/openai_v2/utils.py b/instrumentation-genai/opentelemetry-instrumentation-openai-v2/src/opentelemetry/instrumentation/openai_v2/utils.py
index cf920c17ee..f8a837259e 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/src/opentelemetry/instrumentation/openai_v2/utils.py
+++ b/instrumentation-genai/opentelemetry-instrumentation-openai-v2/src/opentelemetry/instrumentation/openai_v2/utils.py
@@ -13,7 +13,7 @@
 # limitations under the License.
 
 from os import environ
-from typing import Optional, Union
+from typing import Mapping, Optional, Union
 from urllib.parse import urlparse
 
 from httpx import URL
@@ -202,12 +202,23 @@ def get_llm_request_attributes(
         GenAIAttributes.GEN_AI_REQUEST_FREQUENCY_PENALTY: kwargs.get(
             "frequency_penalty"
         ),
-        GenAIAttributes.GEN_AI_OPENAI_REQUEST_RESPONSE_FORMAT: kwargs.get(
-            "response_format"
-        ),
         GenAIAttributes.GEN_AI_OPENAI_REQUEST_SEED: kwargs.get("seed"),
     }
 
+    if (response_format := kwargs.get("response_format")) is not None:
+        # response_format may be string or object with a string in the `type` key
+        if isinstance(response_format, Mapping):
+            if (
+                response_format_type := response_format.get("type")
+            ) is not None:
+                attributes[
+                    GenAIAttributes.GEN_AI_OPENAI_REQUEST_RESPONSE_FORMAT
+                ] = response_format_type
+        else:
+            attributes[
+                GenAIAttributes.GEN_AI_OPENAI_REQUEST_RESPONSE_FORMAT
+            ] = response_format
+
     set_server_address_and_port(client_instance, attributes)
     service_tier = kwargs.get("service_tier")
     attributes[GenAIAttributes.GEN_AI_OPENAI_RESPONSE_SERVICE_TIER] = (
diff --git a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/tests/cassettes/test_async_chat_completion_extra_params.yaml b/instrumentation-genai/opentelemetry-instrumentation-openai-v2/tests/cassettes/test_async_chat_completion_extra_params.yaml
index 3d13c9344e..37c18b091a 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/tests/cassettes/test_async_chat_completion_extra_params.yaml
+++ b/instrumentation-genai/opentelemetry-instrumentation-openai-v2/tests/cassettes/test_async_chat_completion_extra_params.yaml
@@ -10,6 +10,9 @@ interactions:
         ],
         "model": "gpt-4o-mini",
         "max_tokens": 50,
+        "response_format": {
+          "type": "text"
+        },
         "seed": 42,
         "stream": false,
         "temperature": 0.5,
@@ -25,7 +28,7 @@ interactions:
       connection:
       - keep-alive
       content-length:
-      - '183'
+      - '220'
       content-type:
       - application/json
       host:
@@ -45,16 +48,16 @@ interactions:
       x-stainless-runtime:
       - CPython
       x-stainless-runtime-version:
-      - 3.12.5
+      - 3.12.7
     method: POST
     uri: https://api.openai.com/v1/chat/completions
   response:
     body:
       string: |-
         {
-          "id": "chatcmpl-ASv9WMTAMZY4O1EImv3csZa6Ch7KI",
+          "id": "chatcmpl-AbMH3rR6OBMN9hG5w0TRrezuiHLMr",
           "object": "chat.completion",
-          "created": 1731456242,
+          "created": 1733467121,
           "model": "gpt-4o-mini-2024-07-18",
           "choices": [
             {
@@ -84,19 +87,19 @@ interactions:
             }
           },
           "service_tier": "default",
-          "system_fingerprint": "fp_0ba0d124f1"
+          "system_fingerprint": "fp_bba3c8e70b"
         }
     headers:
       CF-Cache-Status:
       - DYNAMIC
       CF-RAY:
-      - 8e1a8088f867e167-MRS
+      - 8eda4640ead3e535-KUL
       Connection:
       - keep-alive
       Content-Type:
       - application/json
       Date:
-      - Wed, 13 Nov 2024 00:04:02 GMT
+      - Fri, 06 Dec 2024 06:38:42 GMT
       Server:
       - cloudflare
       Set-Cookie: test_set_cookie
@@ -112,25 +115,25 @@ interactions:
       - '825'
       openai-organization: test_openai_org_id
       openai-processing-ms:
-      - '488'
+      - '835'
       openai-version:
       - '2020-10-01'
       strict-transport-security:
       - max-age=31536000; includeSubDomains; preload
       x-ratelimit-limit-requests:
-      - '30000'
+      - '10000'
       x-ratelimit-limit-tokens:
-      - '150000000'
+      - '200000'
       x-ratelimit-remaining-requests:
-      - '29999'
+      - '9999'
       x-ratelimit-remaining-tokens:
-      - '149999943'
+      - '199943'
       x-ratelimit-reset-requests:
-      - 2ms
+      - 8.64s
       x-ratelimit-reset-tokens:
-      - 0s
+      - 16ms
       x-request-id:
-      - req_6df08d6267415e8f5db3628a6757edad
+      - req_fea877c0a861ff92a6a5217247681f24
     status:
       code: 200
       message: OK
diff --git a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/tests/cassettes/test_chat_completion_extra_params.yaml b/instrumentation-genai/opentelemetry-instrumentation-openai-v2/tests/cassettes/test_chat_completion_extra_params.yaml
index 7cc89ad9b8..87f9673512 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/tests/cassettes/test_chat_completion_extra_params.yaml
+++ b/instrumentation-genai/opentelemetry-instrumentation-openai-v2/tests/cassettes/test_chat_completion_extra_params.yaml
@@ -10,6 +10,9 @@ interactions:
         ],
         "model": "gpt-4o-mini",
         "max_tokens": 50,
+        "response_format": {
+          "type": "text"
+        },
         "seed": 42,
         "stream": false,
         "temperature": 0.5,
@@ -25,13 +28,13 @@ interactions:
       connection:
       - keep-alive
       content-length:
-      - '183'
+      - '220'
       content-type:
       - application/json
       host:
       - api.openai.com
       user-agent:
-      - OpenAI/Python 1.54.3
+      - OpenAI/Python 1.26.0
       x-stainless-arch:
       - arm64
       x-stainless-async:
@@ -41,22 +44,20 @@ interactions:
       x-stainless-os:
       - MacOS
       x-stainless-package-version:
-      - 1.54.3
-      x-stainless-retry-count:
-      - '0'
+      - 1.26.0
       x-stainless-runtime:
       - CPython
       x-stainless-runtime-version:
-      - 3.12.6
+      - 3.12.7
     method: POST
     uri: https://api.openai.com/v1/chat/completions
   response:
     body:
       string: |-
         {
-          "id": "chatcmpl-ASYMT7913Sp58qhZqQgY7g7Ia2J4M",
+          "id": "chatcmpl-AbMH70fQA9lMPIClvBPyBSjqJBm9F",
           "object": "chat.completion",
-          "created": 1731368633,
+          "created": 1733467125,
           "model": "gpt-4o-mini-2024-07-18",
           "choices": [
             {
@@ -86,19 +87,17 @@ interactions:
             }
           },
           "service_tier": "default",
-          "system_fingerprint": "fp_0ba0d124f1"
+          "system_fingerprint": "fp_0705bf87c0"
         }
     headers:
-      CF-Cache-Status:
-      - DYNAMIC
       CF-RAY:
-      - 8e1225a3f8e9ce65-SIN
+      - 8eda465e8fe9e58c-KUL
       Connection:
       - keep-alive
       Content-Type:
       - application/json
       Date:
-      - Mon, 11 Nov 2024 23:43:53 GMT
+      - Fri, 06 Dec 2024 06:38:46 GMT
       Server:
       - cloudflare
       Set-Cookie: test_set_cookie
@@ -110,11 +109,13 @@ interactions:
       - X-Request-ID
       alt-svc:
       - h3=":443"; ma=86400
+      cf-cache-status:
+      - DYNAMIC
       content-length:
       - '825'
       openai-organization: test_openai_org_id
       openai-processing-ms:
-      - '431'
+      - '558'
       openai-version:
       - '2020-10-01'
       strict-transport-security:
@@ -128,11 +129,11 @@ interactions:
       x-ratelimit-remaining-tokens:
       - '199943'
       x-ratelimit-reset-requests:
-      - 14.746s
+      - 12.967s
       x-ratelimit-reset-tokens:
       - 16ms
       x-request-id:
-      - req_81e29a8992ea8001c0240bd990acf0ab
+      - req_22ff608d47a299f0780f52360631eabb
     status:
       code: 200
       message: OK
diff --git a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/tests/test_async_chat_completions.py b/instrumentation-genai/opentelemetry-instrumentation-openai-v2/tests/test_async_chat_completions.py
index e19bc7c311..65c596796d 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/tests/test_async_chat_completions.py
+++ b/instrumentation-genai/opentelemetry-instrumentation-openai-v2/tests/test_async_chat_completions.py
@@ -158,6 +158,7 @@ async def test_async_chat_completion_extra_params(
         max_tokens=50,
         stream=False,
         extra_body={"service_tier": "default"},
+        response_format={"type": "text"},
     )
 
     spans = span_exporter.get_finished_spans()
@@ -173,6 +174,12 @@ async def test_async_chat_completion_extra_params(
         spans[0].attributes[GenAIAttributes.GEN_AI_OPENAI_REQUEST_SERVICE_TIER]
         == "default"
     )
+    assert (
+        spans[0].attributes[
+            GenAIAttributes.GEN_AI_OPENAI_REQUEST_RESPONSE_FORMAT
+        ]
+        == "text"
+    )
 
 
 @pytest.mark.vcr()
diff --git a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/tests/test_chat_completions.py b/instrumentation-genai/opentelemetry-instrumentation-openai-v2/tests/test_chat_completions.py
index 4f732290c0..4677b7cb95 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/tests/test_chat_completions.py
+++ b/instrumentation-genai/opentelemetry-instrumentation-openai-v2/tests/test_chat_completions.py
@@ -151,6 +151,7 @@ def test_chat_completion_extra_params(
         max_tokens=50,
         stream=False,
         extra_body={"service_tier": "default"},
+        response_format={"type": "text"},
     )
 
     spans = span_exporter.get_finished_spans()
@@ -166,6 +167,12 @@ def test_chat_completion_extra_params(
         spans[0].attributes[GenAIAttributes.GEN_AI_OPENAI_REQUEST_SERVICE_TIER]
         == "default"
     )
+    assert (
+        spans[0].attributes[
+            GenAIAttributes.GEN_AI_OPENAI_REQUEST_RESPONSE_FORMAT
+        ]
+        == "text"
+    )
 
 
 @pytest.mark.vcr()
diff --git a/instrumentation/opentelemetry-instrumentation-aiohttp-client/test-requirements.txt b/instrumentation/opentelemetry-instrumentation-aiohttp-client/test-requirements.txt
index 8a0c88f805..04f853bdbf 100644
--- a/instrumentation/opentelemetry-instrumentation-aiohttp-client/test-requirements.txt
+++ b/instrumentation/opentelemetry-instrumentation-aiohttp-client/test-requirements.txt
@@ -24,7 +24,7 @@ requests==2.32.3
 tomli==2.0.1
 typing_extensions==4.12.2
 urllib3==2.2.2
-Werkzeug==3.0.3
+Werkzeug==3.0.6
 wrapt==1.16.0
 yarl==1.9.4
 zipp==3.19.2
diff --git a/instrumentation/opentelemetry-instrumentation-aiokafka/src/opentelemetry/instrumentation/aiokafka/__init__.py b/instrumentation/opentelemetry-instrumentation-aiokafka/src/opentelemetry/instrumentation/aiokafka/__init__.py
index 507206f4f2..4b14ace4fb 100644
--- a/instrumentation/opentelemetry-instrumentation-aiokafka/src/opentelemetry/instrumentation/aiokafka/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-aiokafka/src/opentelemetry/instrumentation/aiokafka/__init__.py
@@ -18,7 +18,7 @@
 Usage
 -----
 
-..code:: python
+.. code:: python
 
     from opentelemetry.instrumentation.aiokafka import AIOKafkaInstrumentor
     from aiokafka import AIOKafkaProducer, AIOKafkaConsumer
@@ -45,7 +45,8 @@ def async_produce_hook(span: Span, args, kwargs)
 def async_consume_hook(span: Span, record: kafka.record.ABCRecord, args, kwargs)
 for example:
 
-.. code: python
+.. code:: python
+
     from opentelemetry.instrumentation.kafka import AIOKafkaInstrumentor
     from aiokafka import AIOKafkaProducer, AIOKafkaConsumer
 
diff --git a/instrumentation/opentelemetry-instrumentation-botocore/test-requirements.txt b/instrumentation/opentelemetry-instrumentation-botocore/test-requirements.txt
index 5253cf3bba..aa5f89859f 100644
--- a/instrumentation/opentelemetry-instrumentation-botocore/test-requirements.txt
+++ b/instrumentation/opentelemetry-instrumentation-botocore/test-requirements.txt
@@ -29,7 +29,7 @@ six==1.16.0
 tomli==2.0.1
 typing_extensions==4.12.2
 urllib3==1.26.19
-Werkzeug==3.0.3
+Werkzeug==3.0.6
 wrapt==1.16.0
 xmltodict==0.13.0
 zipp==3.19.2
diff --git a/instrumentation/opentelemetry-instrumentation-confluent-kafka/src/opentelemetry/instrumentation/confluent_kafka/__init__.py b/instrumentation/opentelemetry-instrumentation-confluent-kafka/src/opentelemetry/instrumentation/confluent_kafka/__init__.py
index aaf906d118..48b2bd2c26 100644
--- a/instrumentation/opentelemetry-instrumentation-confluent-kafka/src/opentelemetry/instrumentation/confluent_kafka/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-confluent-kafka/src/opentelemetry/instrumentation/confluent_kafka/__init__.py
@@ -18,7 +18,7 @@
 Usage
 -----
 
-.. code-block:: python
+.. code:: python
 
     from opentelemetry.instrumentation.confluent_kafka import ConfluentKafkaInstrumentor
     from confluent_kafka import Producer, Consumer
@@ -54,7 +54,6 @@ def basic_consume_loop(consumer, topics):
             consumer.close()
 
     basic_consume_loop(consumer, "my-topic")
-    ---
 
 The _instrument method accepts the following keyword args:
   tracer_provider (TracerProvider) - an optional tracer provider
@@ -95,7 +94,6 @@ def instrument_consumer(consumer: Consumer, tracer_provider=None)
     p.produce('my-topic',b'raw_bytes')
     msg = c.poll()
 
-___
 """
 
 from typing import Collection
diff --git a/instrumentation/opentelemetry-instrumentation-django/test-requirements-2.txt b/instrumentation/opentelemetry-instrumentation-django/test-requirements-2.txt
index 1ee4b0bfbf..6d84c3db89 100644
--- a/instrumentation/opentelemetry-instrumentation-django/test-requirements-2.txt
+++ b/instrumentation/opentelemetry-instrumentation-django/test-requirements-2.txt
@@ -1,7 +1,7 @@
 asgiref==3.8.1
 backports.zoneinfo==0.2.1
 Deprecated==1.2.14
-Django==4.2.15
+Django==4.2.17
 iniconfig==2.0.0
 packaging==24.0
 pluggy==1.5.0
diff --git a/instrumentation/opentelemetry-instrumentation-django/test-requirements-3.txt b/instrumentation/opentelemetry-instrumentation-django/test-requirements-3.txt
index aba0b28fa2..61ed226da4 100644
--- a/instrumentation/opentelemetry-instrumentation-django/test-requirements-3.txt
+++ b/instrumentation/opentelemetry-instrumentation-django/test-requirements-3.txt
@@ -1,6 +1,6 @@
 asgiref==3.8.1
 Deprecated==1.2.14
-Django==4.2.15
+Django==4.2.17
 iniconfig==2.0.0
 packaging==24.0
 pluggy==1.5.0
diff --git a/instrumentation/opentelemetry-instrumentation-flask/test-requirements-2.txt b/instrumentation/opentelemetry-instrumentation-flask/test-requirements-2.txt
index 59edf6f540..d7bf77e315 100644
--- a/instrumentation/opentelemetry-instrumentation-flask/test-requirements-2.txt
+++ b/instrumentation/opentelemetry-instrumentation-flask/test-requirements-2.txt
@@ -13,7 +13,7 @@ py-cpuinfo==9.0.0
 pytest==7.4.4
 tomli==2.0.1
 typing_extensions==4.12.2
-Werkzeug==3.0.3
+Werkzeug==3.0.6
 wrapt==1.16.0
 zipp==3.19.2
 -e opentelemetry-instrumentation
diff --git a/instrumentation/opentelemetry-instrumentation-kafka-python/src/opentelemetry/instrumentation/kafka/__init__.py b/instrumentation/opentelemetry-instrumentation-kafka-python/src/opentelemetry/instrumentation/kafka/__init__.py
index 9b0f4895f9..1e0dbf79e1 100644
--- a/instrumentation/opentelemetry-instrumentation-kafka-python/src/opentelemetry/instrumentation/kafka/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-kafka-python/src/opentelemetry/instrumentation/kafka/__init__.py
@@ -18,7 +18,7 @@
 Usage
 -----
 
-..code:: python
+.. code:: python
 
     from opentelemetry.instrumentation.kafka import KafkaInstrumentor
     from kafka import KafkaProducer, KafkaConsumer
@@ -45,7 +45,8 @@ def produce_hook(span: Span, args, kwargs)
 def consume_hook(span: Span, record: kafka.record.ABCRecord, args, kwargs)
 for example:
 
-.. code: python
+.. code:: python
+
     from opentelemetry.instrumentation.kafka import KafkaInstrumentor
     from kafka import KafkaProducer, KafkaConsumer
 
diff --git a/instrumentation/opentelemetry-instrumentation-pyramid/test-requirements.txt b/instrumentation/opentelemetry-instrumentation-pyramid/test-requirements.txt
index 97815133f8..157b9b6040 100644
--- a/instrumentation/opentelemetry-instrumentation-pyramid/test-requirements.txt
+++ b/instrumentation/opentelemetry-instrumentation-pyramid/test-requirements.txt
@@ -15,7 +15,7 @@ translationstring==1.4
 typing_extensions==4.12.2
 venusian==3.1.0
 WebOb==1.8.8
-Werkzeug==3.0.3
+Werkzeug==3.0.6
 wrapt==1.16.0
 zipp==3.19.2
 zope.deprecation==5.0
diff --git a/instrumentation/opentelemetry-instrumentation-sqlalchemy/src/opentelemetry/instrumentation/sqlalchemy/__init__.py b/instrumentation/opentelemetry-instrumentation-sqlalchemy/src/opentelemetry/instrumentation/sqlalchemy/__init__.py
index 9889e18b5a..4182c0034e 100644
--- a/instrumentation/opentelemetry-instrumentation-sqlalchemy/src/opentelemetry/instrumentation/sqlalchemy/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-sqlalchemy/src/opentelemetry/instrumentation/sqlalchemy/__init__.py
@@ -181,6 +181,18 @@ def _instrument(self, **kwargs):
                 tracer, connections_usage, enable_commenter, commenter_options
             ),
         )
+        # sqlalchemy.engine.create is not present in earlier versions of sqlalchemy (which we support)
+        if parse_version(sqlalchemy.__version__).release >= (1, 4):
+            _w(
+                "sqlalchemy.engine.create",
+                "create_engine",
+                _wrap_create_engine(
+                    tracer,
+                    connections_usage,
+                    enable_commenter,
+                    commenter_options,
+                ),
+            )
         _w(
             "sqlalchemy.engine.base",
             "Engine.connect",
@@ -224,6 +236,8 @@ def _instrument(self, **kwargs):
     def _uninstrument(self, **kwargs):
         unwrap(sqlalchemy, "create_engine")
         unwrap(sqlalchemy.engine, "create_engine")
+        if parse_version(sqlalchemy.__version__).release >= (1, 4):
+            unwrap(sqlalchemy.engine.create, "create_engine")
         unwrap(Engine, "connect")
         if parse_version(sqlalchemy.__version__).release >= (1, 4):
             unwrap(sqlalchemy.ext.asyncio, "create_async_engine")
diff --git a/instrumentation/opentelemetry-instrumentation-sqlalchemy/tests/test_sqlalchemy.py b/instrumentation/opentelemetry-instrumentation-sqlalchemy/tests/test_sqlalchemy.py
index 18b9fa65f7..27a253decb 100644
--- a/instrumentation/opentelemetry-instrumentation-sqlalchemy/tests/test_sqlalchemy.py
+++ b/instrumentation/opentelemetry-instrumentation-sqlalchemy/tests/test_sqlalchemy.py
@@ -182,6 +182,17 @@ def test_create_engine_wrapper(self):
             "opentelemetry.instrumentation.sqlalchemy",
         )
 
+    def test_instrument_engine_from_config(self):
+        SQLAlchemyInstrumentor().instrument()
+        from sqlalchemy import engine_from_config  # pylint: disable-all
+
+        engine = engine_from_config({"sqlalchemy.url": "sqlite:///:memory:"})
+        cnx = engine.connect()
+        cnx.execute(text("SELECT	1 + 1;")).fetchall()
+        spans = self.memory_exporter.get_finished_spans()
+
+        self.assertEqual(len(spans), 2)
+
     def test_create_engine_wrapper_enable_commenter(self):
         logging.getLogger("sqlalchemy.engine").setLevel(logging.INFO)
         SQLAlchemyInstrumentor().instrument(
diff --git a/instrumentation/opentelemetry-instrumentation-sqlite3/src/opentelemetry/instrumentation/sqlite3/__init__.py b/instrumentation/opentelemetry-instrumentation-sqlite3/src/opentelemetry/instrumentation/sqlite3/__init__.py
index 9b3ae28a95..1ec4794e96 100644
--- a/instrumentation/opentelemetry-instrumentation-sqlite3/src/opentelemetry/instrumentation/sqlite3/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-sqlite3/src/opentelemetry/instrumentation/sqlite3/__init__.py
@@ -39,20 +39,27 @@
 ---
 """
 
+from __future__ import annotations
+
 import sqlite3
 from sqlite3 import dbapi2
-from typing import Collection
+from typing import Any, Collection, TypeVar, Union
 
 from opentelemetry.instrumentation import dbapi
 from opentelemetry.instrumentation.instrumentor import BaseInstrumentor
 from opentelemetry.instrumentation.sqlite3.package import _instruments
 from opentelemetry.instrumentation.sqlite3.version import __version__
+from opentelemetry.trace import TracerProvider
 
 # No useful attributes of sqlite3 connection object
 _CONNECTION_ATTRIBUTES = {}
 
 _DATABASE_SYSTEM = "sqlite"
 
+SQLite3Connection = TypeVar(  # pylint: disable=invalid-name
+    "SQLite3Connection", bound=Union[sqlite3.Connection, None]
+)
+
 
 class SQLite3Instrumentor(BaseInstrumentor):
     _TO_WRAP = [sqlite3, dbapi2]
@@ -60,7 +67,7 @@ class SQLite3Instrumentor(BaseInstrumentor):
     def instrumentation_dependencies(self) -> Collection[str]:
         return _instruments
 
-    def _instrument(self, **kwargs):
+    def _instrument(self, **kwargs: Any) -> None:
         """Integrate with SQLite3 Python library.
         https://docs.python.org/3/library/sqlite3.html
         """
@@ -77,13 +84,16 @@ def _instrument(self, **kwargs):
                 tracer_provider=tracer_provider,
             )
 
-    def _uninstrument(self, **kwargs):
+    def _uninstrument(self, **kwargs: Any) -> None:
         """ "Disable SQLite3 instrumentation"""
         for module in self._TO_WRAP:
             dbapi.unwrap_connect(module, "connect")
 
     @staticmethod
-    def instrument_connection(connection, tracer_provider=None):
+    def instrument_connection(
+        connection: SQLite3Connection,
+        tracer_provider: TracerProvider | None = None,
+    ) -> SQLite3Connection:
         """Enable instrumentation in a SQLite connection.
 
         Args:
@@ -105,7 +115,9 @@ def instrument_connection(connection, tracer_provider=None):
         )
 
     @staticmethod
-    def uninstrument_connection(connection):
+    def uninstrument_connection(
+        connection: SQLite3Connection,
+    ) -> SQLite3Connection:
         """Disable instrumentation in a SQLite connection.
 
         Args:
diff --git a/instrumentation/opentelemetry-instrumentation-sqlite3/src/opentelemetry/instrumentation/sqlite3/package.py b/instrumentation/opentelemetry-instrumentation-sqlite3/src/opentelemetry/instrumentation/sqlite3/package.py
index 7a66a17a93..0de6133b4a 100644
--- a/instrumentation/opentelemetry-instrumentation-sqlite3/src/opentelemetry/instrumentation/sqlite3/package.py
+++ b/instrumentation/opentelemetry-instrumentation-sqlite3/src/opentelemetry/instrumentation/sqlite3/package.py
@@ -11,6 +11,6 @@
 # WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
 # See the License for the specific language governing permissions and
 # limitations under the License.
+from __future__ import annotations
 
-
-_instruments = tuple()
+_instruments: tuple[str, ...] = tuple()
diff --git a/instrumentation/opentelemetry-instrumentation-tornado/test-requirements.txt b/instrumentation/opentelemetry-instrumentation-tornado/test-requirements.txt
index 56a088ec62..2df7df38ec 100644
--- a/instrumentation/opentelemetry-instrumentation-tornado/test-requirements.txt
+++ b/instrumentation/opentelemetry-instrumentation-tornado/test-requirements.txt
@@ -17,10 +17,10 @@ py-cpuinfo==9.0.0
 pytest==7.4.4
 requests==2.32.3
 tomli==2.0.1
-tornado==6.4.1
+tornado==6.4.2
 typing_extensions==4.12.2
 urllib3==2.2.2
-Werkzeug==3.0.3
+Werkzeug==3.0.6
 wrapt==1.16.0
 zipp==3.19.2
 -e opentelemetry-instrumentation
diff --git a/rtd-requirements.txt b/rtd-requirements.txt
new file mode 100644
index 0000000000..b68781bd8c
--- /dev/null
+++ b/rtd-requirements.txt
@@ -0,0 +1,7 @@
+# Need to install the api/sdk in the venv for autodoc. Used by .readthedocs.yml
+opentelemetry-api @ git+https://github.com/open-telemetry/opentelemetry-python.git@main#egg=opentelemetry-api&subdirectory=opentelemetry-api
+opentelemetry-semantic-conventions @ git+https://github.com/open-telemetry/opentelemetry-python.git@main#egg=opentelemetry-semantic-conventions&subdirectory=opentelemetry-semantic-conventions
+opentelemetry-sdk @ git+https://github.com/open-telemetry/opentelemetry-python.git@main#egg=opentelemetry-sdk&subdirectory=opentelemetry-sdk
+./opentelemetry-instrumentation
+./util/opentelemetry-util-http
+-r ./docs-requirements.txt