diff --git a/experimental/CHANGELOG.md b/experimental/CHANGELOG.md
index 4ffc9cdc6fc..abec890a38c 100644
--- a/experimental/CHANGELOG.md
+++ b/experimental/CHANGELOG.md
@@ -10,7 +10,9 @@ All notable changes to experimental packages in this project will be documented
 
 ### :bug: (Bug Fix)
 
-fix(instrumentation): use caret range on import-in-the-middle [#4380](https://github.com/open-telemetry/opentelemetry-js/pull/4380) @pichlermarc
+* fix(instrumentation): use caret range on import-in-the-middle [#4380](https://github.com/open-telemetry/opentelemetry-js/pull/4380) @pichlermarc
+* fix(instrumentation): do not import 'path' in browser runtimes [#4378](https://github.com/open-telemetry/opentelemetry-js/pull/4378) @pichlermarc
+  * Fixes a bug where bundling for web would fail due to `InstrumentationNodeModuleDefinition` importing `path`
 
 ### :books: (Refine Doc)
 
diff --git a/experimental/packages/opentelemetry-instrumentation/src/instrumentationNodeModuleFile.ts b/experimental/packages/opentelemetry-instrumentation/src/instrumentationNodeModuleFile.ts
index 574f17257e8..edbe8ba72eb 100644
--- a/experimental/packages/opentelemetry-instrumentation/src/instrumentationNodeModuleFile.ts
+++ b/experimental/packages/opentelemetry-instrumentation/src/instrumentationNodeModuleFile.ts
@@ -15,7 +15,7 @@
  */
 
 import { InstrumentationModuleFile } from './types';
-import { normalize } from 'path';
+import { normalize } from './platform/index';
 
 export class InstrumentationNodeModuleFile<T>
   implements InstrumentationModuleFile<T>
diff --git a/experimental/packages/opentelemetry-instrumentation/src/platform/browser/index.ts b/experimental/packages/opentelemetry-instrumentation/src/platform/browser/index.ts
index 0b238b42b8a..4ad5c8f063d 100644
--- a/experimental/packages/opentelemetry-instrumentation/src/platform/browser/index.ts
+++ b/experimental/packages/opentelemetry-instrumentation/src/platform/browser/index.ts
@@ -15,3 +15,4 @@
  */
 
 export { InstrumentationBase } from './instrumentation';
+export { normalize } from './noop-normalize';
diff --git a/experimental/packages/opentelemetry-instrumentation/src/platform/browser/noop-normalize.ts b/experimental/packages/opentelemetry-instrumentation/src/platform/browser/noop-normalize.ts
new file mode 100644
index 00000000000..7b8aa40000f
--- /dev/null
+++ b/experimental/packages/opentelemetry-instrumentation/src/platform/browser/noop-normalize.ts
@@ -0,0 +1,35 @@
+/*
+ * Copyright The OpenTelemetry Authors
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *      https://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+
+import { diag } from '@opentelemetry/api';
+
+/**
+ * Placeholder normalize function to replace the node variant in browser runtimes,
+ * this should never be called and will perform a no-op and warn if it is called regardless.
+ *
+ * This is a workaround to fix https://github.com/open-telemetry/opentelemetry-js/issues/4373 until the instrumentation
+ * package can be made node-only.
+ *
+ * @param path input path
+ * @return unmodified path
+ * @internal
+ */
+export function normalize(path: string): string {
+  diag.warn(
+    'Path normalization is not implemented for this platform. To silence this warning, ensure no node-specific instrumentations are loaded, and node-specific types (e.g. InstrumentationNodeModuleFile), are not used in a browser context)'
+  );
+  return path;
+}
diff --git a/experimental/packages/opentelemetry-instrumentation/src/platform/index.ts b/experimental/packages/opentelemetry-instrumentation/src/platform/index.ts
index 81d30962522..f24b70eac5d 100644
--- a/experimental/packages/opentelemetry-instrumentation/src/platform/index.ts
+++ b/experimental/packages/opentelemetry-instrumentation/src/platform/index.ts
@@ -14,4 +14,4 @@
  * limitations under the License.
  */
 
-export { InstrumentationBase } from './node';
+export { InstrumentationBase, normalize } from './node';
diff --git a/experimental/packages/opentelemetry-instrumentation/src/platform/node/index.ts b/experimental/packages/opentelemetry-instrumentation/src/platform/node/index.ts
index 1e81931b2a0..94f517dfa37 100644
--- a/experimental/packages/opentelemetry-instrumentation/src/platform/node/index.ts
+++ b/experimental/packages/opentelemetry-instrumentation/src/platform/node/index.ts
@@ -14,3 +14,4 @@
  * limitations under the License.
  */
 export { InstrumentationBase } from './instrumentation';
+export { normalize } from './normalize';
diff --git a/experimental/packages/opentelemetry-instrumentation/src/platform/node/normalize.ts b/experimental/packages/opentelemetry-instrumentation/src/platform/node/normalize.ts
new file mode 100644
index 00000000000..83b83aaef21
--- /dev/null
+++ b/experimental/packages/opentelemetry-instrumentation/src/platform/node/normalize.ts
@@ -0,0 +1,17 @@
+/*
+ * Copyright The OpenTelemetry Authors
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *      https://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+
+export { normalize } from 'path';
diff --git a/experimental/packages/opentelemetry-instrumentation/test/browser/noop-normalize.test.ts b/experimental/packages/opentelemetry-instrumentation/test/browser/noop-normalize.test.ts
new file mode 100644
index 00000000000..aedcb975e7c
--- /dev/null
+++ b/experimental/packages/opentelemetry-instrumentation/test/browser/noop-normalize.test.ts
@@ -0,0 +1,24 @@
+/*
+ * Copyright The OpenTelemetry Authors
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *      https://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+
+import * as assert from 'assert';
+import { normalize } from '../../src/platform/browser';
+
+describe('noop-normalize', function () {
+  it('should not normalize input', function () {
+    assert.strictEqual(normalize('/tmp/foo/../bar'), '/tmp/foo/../bar');
+  });
+});