diff --git a/docs/odk-workflows/RepositoryFileStructure.md b/docs/odk-workflows/RepositoryFileStructure.md
index f42d81550..7ea05c01c 100644
--- a/docs/odk-workflows/RepositoryFileStructure.md
+++ b/docs/odk-workflows/RepositoryFileStructure.md
@@ -23,7 +23,6 @@ These are the current imports in CL
 | ro | http://purl.obolibrary.org/obo/ro.owl | None |
 | pato | http://purl.obolibrary.org/obo/pato.owl | None |
 | ncbitaxon | http://purl.obolibrary.org/obo/ncbitaxon/subsets/taxslim.owl | None |
-| iao | http://purl.obolibrary.org/obo/iao.owl | None |
 
 ## Components
 Components, in contrast to imports, are considered full members of the ontology. This means that any axiom in a component is also included in the ontology base - which means it is considered _native_ to the ontology. While this sounds complicated, consider this: conceptually, no component should be part of more than one ontology. If that seems to be the case, we are most likely talking about an import. Components are often not needed for ontologies, but there are some use cases:
diff --git a/src/ontology/Makefile b/src/ontology/Makefile
index bb0294b84..b604bab1e 100644
--- a/src/ontology/Makefile
+++ b/src/ontology/Makefile
@@ -113,7 +113,7 @@ all_main: $(MAIN_FILES)
 # ----------------------------------------
 
 
-IMPORTS =  pr go caro uberon ro pato ncbitaxon iao
+IMPORTS =  pr go caro uberon ro pato ncbitaxon
 
 IMPORT_ROOTS =  $(IMPORTDIR)/merged_import
 IMPORT_OWL_FILES = $(foreach n,$(IMPORT_ROOTS), $(n).owl)
@@ -489,16 +489,6 @@ mirror-ncbitaxon: | $(TMPDIR)
 	if [ $(MIR) = true ] && [ $(IMP) = true ]; then $(ROBOT) convert -I http://purl.obolibrary.org/obo/ncbitaxon/subsets/taxslim.owl -o $@.tmp.owl &&\
 		mv $@.tmp.owl $(TMPDIR)/$@.owl; fi
 
-
-## ONTOLOGY: iao
-.PHONY: mirror-iao
-.PRECIOUS: $(MIRRORDIR)/iao.owl
-mirror-iao: | $(TMPDIR)
-	if [ $(MIR) = true ] && [ $(IMP) = true ]; then curl -L $(OBOBASE)/iao.owl --create-dirs -o $(MIRRORDIR)/iao.owl --retry 4 --max-time 200 &&\
-		$(ROBOT) convert -i $(MIRRORDIR)/iao.owl -o $@.tmp.owl && \
-		$(ROBOT) remove -i $@.tmp.owl --base-iri $(URIBASE)/IAO --axioms external --preserve-structure false --trim false -o $@.tmp.owl &&\
-		mv $@.tmp.owl $(TMPDIR)/$@.owl; fi
-
 ALL_MIRRORS = $(patsubst %, $(MIRRORDIR)/%.owl, $(IMPORTS))
 MERGE_MIRRORS = true
 
diff --git a/src/ontology/cl-edit.owl b/src/ontology/cl-edit.owl
index 1e71ab09d..6697b382c 100644
--- a/src/ontology/cl-edit.owl
+++ b/src/ontology/cl-edit.owl
@@ -3173,6 +3173,10 @@ Declaration(AnnotationProperty(owl:deprecated))
 #   Annotation Properties
 ############################
 
+# Annotation Property: obo:IAO_0000028 (symbol)
+
+AnnotationAssertion(rdfs:label obo:IAO_0000028 "symbol")
+
 # Annotation Property: obo:IAO_0000115 (definition)
 
 AnnotationAssertion(rdfs:label obo:IAO_0000115 "definition")
diff --git a/src/ontology/cl-odk.yaml b/src/ontology/cl-odk.yaml
index 62751569a..5d8f91b7d 100644
--- a/src/ontology/cl-odk.yaml
+++ b/src/ontology/cl-odk.yaml
@@ -68,8 +68,6 @@ import_group:
       use_base: TRUE
     - id: ncbitaxon
       mirror_from: http://purl.obolibrary.org/obo/ncbitaxon/subsets/taxslim.owl
-    - id: iao
-      make_base: TRUE
 pattern_pipelines_group:
   products:
     - id: clustering
diff --git a/src/ontology/imports/iao_terms.txt b/src/ontology/imports/iao_terms.txt
deleted file mode 100644
index 3b0a375b6..000000000
--- a/src/ontology/imports/iao_terms.txt
+++ /dev/null
@@ -1 +0,0 @@
-IAO:0000028
diff --git a/src/ontology/imports/merged_import.owl b/src/ontology/imports/merged_import.owl
index fa4ba197a..678d15d9f 100644
--- a/src/ontology/imports/merged_import.owl
+++ b/src/ontology/imports/merged_import.owl
@@ -7,10 +7,9 @@ Prefix(rdfs:=<http://www.w3.org/2000/01/rdf-schema#>)
 
 
 Ontology(<http://purl.obolibrary.org/obo/cl/imports/merged_import.owl>
-<http://purl.obolibrary.org/obo/cl/releases/2023-07-19/imports/merged_import.owl>
-Annotation(owl:versionInfo "2023-07-19")
+<http://purl.obolibrary.org/obo/cl/releases/2023-08-09/imports/merged_import.owl>
+Annotation(owl:versionInfo "2023-08-09")
 
-Declaration(Class(<http://purl.obolibrary.org/obo/BFO_0000001>))
 Declaration(Class(<http://purl.obolibrary.org/obo/BFO_0000002>))
 Declaration(Class(<http://purl.obolibrary.org/obo/BFO_0000003>))
 Declaration(Class(<http://purl.obolibrary.org/obo/BFO_0000004>))
@@ -138,7 +137,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_37395>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_37396>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_37397>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_3892>))
-Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_43474>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_456216>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_46858>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_50047>))
@@ -151,13 +149,11 @@ Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_5391>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_5686>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_57305>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_57595>))
-Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_57930>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_58432>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_59888>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_59905>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_60924>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_61120>))
-Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_61557>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_63299>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_64600>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CHEBI_64628>))
@@ -218,7 +214,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/CL_0000108>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0000115>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0000118>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0000119>))
-Declaration(Class(<http://purl.obolibrary.org/obo/CL_0000120>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0000121>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0000122>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0000125>))
@@ -518,6 +513,7 @@ Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002173>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002174>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002187>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002199>))
+Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002208>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002209>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002220>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002240>))
@@ -535,6 +531,8 @@ Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002319>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002320>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002324>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002327>))
+Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002329>))
+Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002332>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002350>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002355>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002367>))
@@ -560,6 +558,7 @@ Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002543>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002548>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002563>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002573>))
+Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002598>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002608>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002630>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0002633>))
@@ -595,6 +594,7 @@ Declaration(Class(<http://purl.obolibrary.org/obo/CL_0008025>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0008026>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0009001>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0009004>))
+Declaration(Class(<http://purl.obolibrary.org/obo/CL_0009089>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0010005>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0010006>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0010007>))
@@ -619,6 +619,9 @@ Declaration(Class(<http://purl.obolibrary.org/obo/CL_0011108>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0012000>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0012001>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0013000>))
+Declaration(Class(<http://purl.obolibrary.org/obo/CL_0017000>))
+Declaration(Class(<http://purl.obolibrary.org/obo/CL_0019002>))
+Declaration(Class(<http://purl.obolibrary.org/obo/CL_0019019>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_1000001>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_1000022>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_1000042>))
@@ -681,11 +684,12 @@ Declaration(Class(<http://purl.obolibrary.org/obo/CL_2000038>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_2000039>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_2000056>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_2000075>))
+Declaration(Class(<http://purl.obolibrary.org/obo/CL_2000089>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_2000097>))
+Declaration(Class(<http://purl.obolibrary.org/obo/CL_4033017>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000003>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000011>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000018>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000045>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000070>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000139>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000226>))
@@ -697,7 +701,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000280>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000303>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000313>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000323>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000421>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000578>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000740>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000741>))
@@ -708,7 +711,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000792>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000819>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000820>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000902>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0000904>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0001101>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0001501>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0001503>))
@@ -808,7 +810,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0001865>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0001866>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0001873>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0001878>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0001880>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0001885>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0001886>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0001889>))
@@ -1445,7 +1446,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0003824>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0004518>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0004536>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0004672>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0004674>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0004713>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0004714>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0004883>))
@@ -1522,7 +1522,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0005766>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0005773>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0005774>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0005775>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0005776>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0005794>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0005798>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0005840>))
@@ -1645,7 +1644,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0006900>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0006903>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0006906>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0006909>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0006914>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0006915>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0006921>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0006925>))
@@ -1820,12 +1818,10 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008088>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008089>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008090>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008092>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008094>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008104>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008134>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008150>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008152>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008186>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008188>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008201>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008202>))
@@ -1865,7 +1861,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008585>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008594>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008595>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008610>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008641>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008643>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008645>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0008652>))
@@ -1882,12 +1877,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0009071>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0009084>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0009100>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0009101>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0009132>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0009133>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0009134>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0009141>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0009142>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0009143>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0009250>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0009251>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0009266>))
@@ -1985,9 +1974,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010470>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010481>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010482>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010496>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010506>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010507>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010508>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010543>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010544>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010549>))
@@ -2068,7 +2054,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010761>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010762>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010763>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010764>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010769>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010770>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010771>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0010816>))
@@ -2291,10 +2276,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016070>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016079>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016192>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016202>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016236>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016239>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016241>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016242>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016301>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016310>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016319>))
@@ -2306,7 +2287,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016444>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016445>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016446>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016447>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016462>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016477>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016485>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016486>))
@@ -2317,21 +2297,13 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016594>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016595>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016597>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016740>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016746>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016755>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016772>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016773>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016787>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016788>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016817>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016818>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016874>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016877>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016887>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016907>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0016917>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0017046>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0017111>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0017126>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0017145>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0017148>))
@@ -2370,10 +2342,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0019725>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0019730>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0019748>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0019752>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0019777>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0019778>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0019786>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0019787>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0019814>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0019815>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0019825>))
@@ -2720,7 +2688,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0030334>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0030335>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0030336>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0030397>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0030399>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0030421>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0030424>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0030425>))
@@ -3047,8 +3014,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0032763>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0032764>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0032765>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0032774>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0032780>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0032781>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0032782>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0032787>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0032790>))
@@ -3285,8 +3250,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0035040>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0035045>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0035050>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0035051>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0035070>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0035071>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0035082>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0035099>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0035107>))
@@ -3776,7 +3739,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0043417>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0043434>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0043436>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0043455>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0043462>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0043467>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0043470>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0043473>))
@@ -3862,7 +3824,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0044566>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0044703>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0044706>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0044782>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0044804>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0044872>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0044873>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0044874>))
@@ -4241,7 +4202,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0048066>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0048070>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0048086>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0048087>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0048102>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0048103>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0048132>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0048133>))
@@ -4711,13 +4671,10 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0051303>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0051321>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0051336>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0051338>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0051340>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0051345>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0051346>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0051347>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0051348>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0051351>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0051352>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0051355>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0051356>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0051378>))
@@ -4879,8 +4836,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0060017>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0060019>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0060020>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0060021>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0060032>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0060033>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0060034>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0060037>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0060038>))
@@ -5110,7 +5065,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0060619>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0060623>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0060627>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0060632>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0060641>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0060642>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0060643>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0060644>))
@@ -5473,15 +5427,10 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061584>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061585>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061626>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061629>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061650>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061651>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061659>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061660>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061682>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061683>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061687>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061695>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061736>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061792>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061844>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061847>))
@@ -5498,8 +5447,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061888>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061889>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061890>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061900>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061906>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061919>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061938>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061951>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0061971>))
@@ -5634,7 +5581,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0070948>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0070954>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0070960>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0070977>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0070997>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0070998>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0070999>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0071168>))
@@ -5732,9 +5678,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0071888>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0071890>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0071895>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0071897>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0071900>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0071901>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0071902>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0071941>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0071944>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0071953>))
@@ -6476,7 +6419,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0140513>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0140572>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0140640>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0140650>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_0140657>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0140667>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0140668>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0140669>))
@@ -6615,9 +6557,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_1901203>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1901210>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1901211>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1901212>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_1901214>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_1901215>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_1901216>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1901219>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1901220>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1901221>))
@@ -6786,7 +6725,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_1902513>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1902531>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1902532>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1902533>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_1902554>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1902563>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1902564>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1902565>))
@@ -6847,7 +6785,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_1902871>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1902875>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1902876>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1902877>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_1902902>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1902903>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1902904>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1902905>))
@@ -7063,9 +7000,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904065>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904073>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904074>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904075>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904092>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904093>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904094>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904106>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904115>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904116>))
@@ -7205,7 +7139,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904709>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904710>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904724>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904738>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904745>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904746>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904747>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904748>))
@@ -7254,7 +7187,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904942>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904943>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904944>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904948>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904949>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904950>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904951>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904956>))
@@ -7265,7 +7197,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904977>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904987>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904988>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1904989>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905037>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905039>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905040>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905063>))
@@ -7283,7 +7214,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905081>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905109>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905110>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905111>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905114>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905126>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905127>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905128>))
@@ -7437,9 +7367,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905810>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905811>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905821>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905833>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905864>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905865>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905866>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905867>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905871>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1905872>))
@@ -7482,7 +7409,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_1990239>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1990254>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1990266>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1990280>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_1990316>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1990351>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1990375>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_1990379>))
@@ -7750,8 +7676,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_2000739>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_2000740>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_2000741>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_2000768>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_2000785>))
-Declaration(Class(<http://purl.obolibrary.org/obo/GO_2000786>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_2000790>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_2000791>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_2000792>))
@@ -7857,13 +7781,6 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_2001252>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_2001257>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_2001258>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_2001259>))
-Declaration(Class(<http://purl.obolibrary.org/obo/IAO_0000027>))
-Declaration(Class(<http://purl.obolibrary.org/obo/IAO_0000028>))
-Declaration(Class(<http://purl.obolibrary.org/obo/IAO_0000030>))
-Declaration(Class(<http://purl.obolibrary.org/obo/IAO_0000078>))
-Declaration(Class(<http://purl.obolibrary.org/obo/IAO_0000102>))
-Declaration(Class(<http://purl.obolibrary.org/obo/IAO_0000225>))
-Declaration(Class(<http://purl.obolibrary.org/obo/IAO_0000409>))
 Declaration(Class(<http://purl.obolibrary.org/obo/NCBITaxon_1>))
 Declaration(Class(<http://purl.obolibrary.org/obo/NCBITaxon_10066>))
 Declaration(Class(<http://purl.obolibrary.org/obo/NCBITaxon_10088>))
@@ -12390,6 +12307,7 @@ Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0010365>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0010366>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0010367>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0010368>))
+Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0010369>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0010370>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0010371>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0010375>))
@@ -13596,6 +13514,7 @@ Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_8600003>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_8600004>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_8600006>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_8600012>))
+Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_8600017>))
 Declaration(ObjectProperty(<http://purl.obolibrary.org/obo/BFO_0000050>))
 Declaration(ObjectProperty(<http://purl.obolibrary.org/obo/BFO_0000051>))
 Declaration(ObjectProperty(<http://purl.obolibrary.org/obo/BFO_0000062>))
@@ -13628,7 +13547,6 @@ Declaration(ObjectProperty(<http://purl.obolibrary.org/obo/BSPO_0015014>))
 Declaration(ObjectProperty(<http://purl.obolibrary.org/obo/BSPO_0015101>))
 Declaration(ObjectProperty(<http://purl.obolibrary.org/obo/GOREL_0002003>))
 Declaration(ObjectProperty(<http://purl.obolibrary.org/obo/GOREL_0002004>))
-Declaration(ObjectProperty(<http://purl.obolibrary.org/obo/IAO_0000136>))
 Declaration(ObjectProperty(<http://purl.obolibrary.org/obo/RO_0000052>))
 Declaration(ObjectProperty(<http://purl.obolibrary.org/obo/RO_0000053>))
 Declaration(ObjectProperty(<http://purl.obolibrary.org/obo/RO_0000056>))
@@ -13893,24 +13811,6 @@ Declaration(ObjectProperty(<http://purl.obolibrary.org/obo/uberon/core#transitiv
 Declaration(ObjectProperty(<http://purl.obolibrary.org/obo/uberon/core#transitively_distally_connected_to>))
 Declaration(ObjectProperty(<http://purl.obolibrary.org/obo/uberon/core#transitively_proximally_connected_to>))
 Declaration(ObjectProperty(<http://purl.obolibrary.org/obo/uberon/core#trunk_part_of>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/IAO_0000002>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/IAO_0000103>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/IAO_0000120>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/IAO_0000121>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/IAO_0000122>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/IAO_0000123>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/IAO_0000124>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/IAO_0000125>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/IAO_0000226>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/IAO_0000227>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/IAO_0000228>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/IAO_0000229>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/IAO_0000410>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/IAO_0000420>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/IAO_0000421>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/IAO_0000423>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/IAO_0000428>))
-Declaration(NamedIndividual(<http://purl.obolibrary.org/obo/OMO_0001000>))
 Declaration(AnnotationProperty(<http://purl.obolibrary.org/obo/IAO_0000111>))
 Declaration(AnnotationProperty(<http://purl.obolibrary.org/obo/IAO_0000112>))
 Declaration(AnnotationProperty(<http://purl.obolibrary.org/obo/IAO_0000114>))
@@ -14066,6 +13966,7 @@ Declaration(AnnotationProperty(<http://purl.org/dc/terms/creator>))
 Declaration(AnnotationProperty(<http://purl.org/dc/terms/date>))
 Declaration(AnnotationProperty(<http://purl.org/dc/terms/license>))
 Declaration(AnnotationProperty(<http://purl.org/dc/terms/source>))
+Declaration(AnnotationProperty(<http://purl.org/dc/terms/title>))
 Declaration(AnnotationProperty(<http://purl.org/spar/cito/citesAsAuthority>))
 Declaration(AnnotationProperty(<http://swrl.stanford.edu/ontologies/3.3/swrla.owl#isRuleEnabled>))
 Declaration(AnnotationProperty(<http://www.geneontology.org/formats/oboInOwl#SubsetProperty>))
@@ -14142,67 +14043,19 @@ Declaration(AnnotationProperty(<https://w3id.org/semapv/vocab/crossSpeciesExactM
 
 # Annotation Property: <http://purl.obolibrary.org/obo/IAO_0000115> (definition)
 
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000115> "definition"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000114> <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000122>)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000115> "The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000115> "2012-04-05: 
-Barry Smith
-
-The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions'  is terrible.
-
-Can you fix to something like:
-
-A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property.
-
-Alan Ruttenberg
-
-Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. 
-
-On the specifics of the proposed definition:
-
-We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. 
-
-Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. 
-
-We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with.  "@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000115> "PERSON:Daniel Schober"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000119> <http://purl.obolibrary.org/obo/IAO_0000115> "GROUP:OBI:<http://purl.obolibrary.org/obo/obi>"@en)
-AnnotationAssertion(rdfs:isDefinedBy <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/iao.owl>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000115> "definition"@en)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000115> "definition")
 
 # Annotation Property: <http://purl.obolibrary.org/obo/IAO_0000116> (editor note)
 
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000116> "editor note"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000114> <http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000122>)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000116> "An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000116> "PERSON:Daniel Schober"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000119> <http://purl.obolibrary.org/obo/IAO_0000116> "GROUP:OBI:<http://purl.obofoundry.org/obo/obi>"@en)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/IAO_0000116> "IAO:0000116")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/IAO_0000116> "uberon")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/IAO_0000116> "editor_note")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#is_metadata_tag> <http://purl.obolibrary.org/obo/IAO_0000116> "true"^^xsd:boolean)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#shorthand> <http://purl.obolibrary.org/obo/IAO_0000116> "editor_note")
-AnnotationAssertion(rdfs:isDefinedBy <http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/iao.owl>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000116> "editor note"@en)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000116> "editor note")
 
-# Annotation Property: <http://purl.obolibrary.org/obo/IAO_0000231> (has obsolescence reason)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000231> "has obsolescence reason"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000231> "Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000231> "PERSON:Alan Ruttenberg"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000231> "PERSON:Melanie Courtot"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000231> "has obsolescence reason"@en)
-
 # Annotation Property: <http://purl.obolibrary.org/obo/IAO_0000233> (term tracker item)
 
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000233> "term tracker item"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000112> <http://purl.obolibrary.org/obo/IAO_0000233> "the URI for an OBI Terms ticket at sourceforge, such as https://sourceforge.net/p/obi/obi-terms/772/"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000114> <http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/IAO_0000125>)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000233> "An IRI or similar locator for a request or discussion of an ontology term."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000233> "Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000119> <http://purl.obolibrary.org/obo/IAO_0000233> "Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg"@en)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/IAO_0000233> "IAO:0000233")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/IAO_0000233> "external")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/IAO_0000233> "uberon")
@@ -14210,44 +14063,25 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#is_class_level> <http://purl.obolibrary.org/obo/IAO_0000233> "true"^^xsd:boolean)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#is_metadata_tag> <http://purl.obolibrary.org/obo/IAO_0000233> "true"^^xsd:boolean)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#shorthand> <http://purl.obolibrary.org/obo/IAO_0000233> "term_tracker_item")
-AnnotationAssertion(rdfs:comment <http://purl.obolibrary.org/obo/IAO_0000233> "The 'tracker item' can associate a tracker with a specific ontology term."@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000233> "term tracker item"@en)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000233> "term tracker item")
 
 # Annotation Property: <http://purl.obolibrary.org/obo/IAO_0000424> (expand expression to)
 
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000424> "expand expression to"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000112> <http://purl.obolibrary.org/obo/IAO_0000424> "ObjectProperty: RO_0002104
-Label: has plasma membrane part
-Annotations: IAO_0000424 \"http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.org/obo/owl/GO#GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)\"
-"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000424> "A macro expansion tag applied to an object property (or possibly a data property)  which can be used by a macro-expansion engine to generate more complex expressions from simpler ones"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000424> "Chris Mungall"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000424> "expand expression to"@en)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000424> "expand expression to")
 
 # Annotation Property: <http://purl.obolibrary.org/obo/IAO_0000700> (has ontology root term)
 
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000700> "has ontology root term"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000700> "Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000700> "Nicolas Matentzoglu"@en)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/IAO_0000700> "IAO:0000700")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/IAO_0000700> "external")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/IAO_0000700> "uberon")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/IAO_0000700> "has_ontology_root_term")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#is_class_level> <http://purl.obolibrary.org/obo/IAO_0000700> "true"^^xsd:boolean)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#is_metadata_tag> <http://purl.obolibrary.org/obo/IAO_0000700> "true"^^xsd:boolean)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#shorthand> <http://purl.obolibrary.org/obo/IAO_0000700> "has_ontology_root_term")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000700> "has ontology root term"@en)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000700> "has ontology root term")
 
 # Annotation Property: <http://purl.obolibrary.org/obo/IAO_0100001> (term replaced by)
 
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0100001> "term replaced by"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000114> <http://purl.obolibrary.org/obo/IAO_0100001> <http://purl.obolibrary.org/obo/IAO_0000125>)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0100001> "Use on obsolete terms, relating the term to another term that can be used as a substitute"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0100001> "Person:Alan Ruttenberg"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000119> <http://purl.obolibrary.org/obo/IAO_0100001> "Person:Alan Ruttenberg"@en)
-AnnotationAssertion(rdfs:comment <http://purl.obolibrary.org/obo/IAO_0100001> "Add as annotation triples in the granting ontology"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0100001> "term replaced by"@en)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0100001> "term replaced by")
 
 # Annotation Property: <http://purl.obolibrary.org/obo/RO_0002161> (never_in_taxon)
@@ -15185,20 +15019,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GOREL_0002004> "r
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GOREL_0002004> "results_in_fission_of")
 SubObjectPropertyOf(<http://purl.obolibrary.org/obo/GOREL_0002004> <http://purl.obolibrary.org/obo/RO_0000057>)
 
-# Object Property: <http://purl.obolibrary.org/obo/IAO_0000136> (is about)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000112> <http://purl.obolibrary.org/obo/IAO_0000136> "This document is about information artifacts and their representations"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000114> <http://purl.obolibrary.org/obo/IAO_0000136> <http://purl.obolibrary.org/obo/IAO_0000125>)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000136> "A (currently) primitive relation that relates an information artifact to an entity."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000136> "7/6/2009 Alan Ruttenberg. Following discussion with Jonathan Rees, and introduction of \"mentions\" relation. Weaken the is_about relationship to be primitive. 
-
-We will try to build it back up by elaborating the various subproperties that are more precisely defined.
-
-Some currently missing phenomena that should be considered \"about\" are predications - \"The only person who knows the answer is sitting beside me\" , Allegory, Satire, and other literary forms that can be topical without explicitly mentioning the topic."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000136> "person:Alan Ruttenberg"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000119> <http://purl.obolibrary.org/obo/IAO_0000136> "Smith, Ceusters, Ruttenberg, 2000 years of philosophy"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000136> "is about"@en)
-
 # Object Property: <http://purl.obolibrary.org/obo/RO_0000052> (characteristic of)
 
 AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/RO_0000052> "inheres in"@en)
@@ -19228,25 +19048,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0000018> "regulation of DNA recombination")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0000018> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_0006310>)))
 
-# Class: <http://purl.obolibrary.org/obo/GO_0000045> (autophagosome assembly)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:9412464") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0000045> "The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0000045> "autophagic vacuole assembly")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0000045> "autophagosome biosynthesis")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0000045> "autophagosome formation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0000045> "PAS formation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0000045> "biological_process")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0000045> "autophagic vacuole formation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0000045> "GO:0000045")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0000045> "autophagosome assembly")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0000045> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0022607> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002588> <http://purl.obolibrary.org/obo/GO_0005776>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0000045> <http://purl.obolibrary.org/obo/GO_0070925>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0000045> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/GO_0019778>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0000045> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/GO_0019786>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0000045> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/GO_0061651>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0000045> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/GO_0061660>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0000045> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002224> <http://purl.obolibrary.org/obo/GO_1904745>))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0000070> (mitotic sister chromatid segregation)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:ai") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:jl") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0000070> "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.")
@@ -19376,17 +19177,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0000323> "lytic vacuole")
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0000323> <http://purl.obolibrary.org/obo/GO_0005773>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0000421> (autophagosome membrane)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:isa_complete") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0000421> "The lipid bilayer surrounding an autophagosome, a double-membrane-bounded vesicle in which endogenous cellular material is sequestered.")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0000421> "autophagic vacuole membrane")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0000421> "cellular_component")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0000421> "GO:0000421")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0000421> "autophagosome membrane")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0000421> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0016020> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002007> <http://purl.obolibrary.org/obo/GO_0005776>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0000421> <http://purl.obolibrary.org/obo/GO_0005774>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0000421> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0005776>))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0000578> (embryonic axis specification)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:go_curators") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:sdb_2009") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:tb") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0000578> "The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo.")
@@ -19511,14 +19301,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <htt
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0000902> "cell morphogenesis")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0000902> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0009653> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002298> <http://purl.obolibrary.org/obo/CL_0000000>)))
 
-# Class: <http://purl.obolibrary.org/obo/GO_0000904> (cell morphogenesis involved in differentiation)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:go_curators") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0000904> "The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0000904> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0000904> "GO:0000904")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0000904> "cell morphogenesis involved in differentiation")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0000904> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0000902> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0048468>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0001101> (response to acid chemical)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:go_curators") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:rn") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0001101> "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.")
@@ -20585,7 +20367,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:comment <http://purl.obolibrary.org/obo/GO_0001831> "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'.")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0001831> "trophectodermal cellular morphogenesis")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0001831> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0009653> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002298> <http://purl.obolibrary.org/obo/CL_1000274>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0001831> <http://purl.obolibrary.org/obo/GO_0000904>)
+SubClassOf(<http://purl.obolibrary.org/obo/GO_0001831> <http://purl.obolibrary.org/obo/GO_0000902>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0001831> <http://purl.obolibrary.org/obo/GO_0048598>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0001831> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0001829>))
 
@@ -20748,17 +20530,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0001878> "resp
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0001878> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0050896> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002233> <http://purl.obolibrary.org/obo/NCBITaxon_147537>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0001878> <http://purl.obolibrary.org/obo/GO_0009620>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0001880> (Mullerian duct regression)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:12368913") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0001880> "The process in which the Mullerian ducts, primordia of the oviducts, uterus and upper vagina, undergo regression in male embryos.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0001880> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0001880> "GO:0001880")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0001880> "Mullerian duct regression")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0001880> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0060033> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002233> <http://purl.obolibrary.org/obo/UBERON_0003890>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0001880> <http://purl.obolibrary.org/obo/GO_0003006>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0001880> <http://purl.obolibrary.org/obo/GO_0060033>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0001880> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0046661>))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0001885> (endothelial cell development)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0001885> "The progression of an endothelial cell over time, from its formation to the mature structure.")
@@ -28008,7 +27779,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0003382> "GO:0003382")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0003382> "epithelial cell morphogenesis")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0003382> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0009653> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002299> <http://purl.obolibrary.org/obo/CL_0000066>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0003382> <http://purl.obolibrary.org/obo/GO_0000904>)
+SubClassOf(<http://purl.obolibrary.org/obo/GO_0003382> <http://purl.obolibrary.org/obo/GO_0000902>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0003382> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0002064>))
 
 # Class: <http://purl.obolibrary.org/obo/GO_0003403> (optic vesicle formation)
@@ -28393,9 +28164,8 @@ SubClassOf(<http://purl.obolibrary.org/obo/GO_0004536> ObjectSomeValuesFrom(<htt
 
 # Class: <http://purl.obolibrary.org/obo/GO_0004672> (protein kinase activity)
 
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "MetaCyc:PROTEIN-KINASE-RXN") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0004672> "Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:25399640") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0004672> "Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_0004672> "GO:0050222")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004672> "MetaCyc:PROTEIN-KINASE-RXN")
 AnnotationAssertion(Annotation(rdfs:label "INF-gamma induced phosphorylation of L13a") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004672> "Reactome:R-HSA-156832")
 AnnotationAssertion(Annotation(rdfs:label "IRAK1 phosphorylates Pellino") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004672> "Reactome:R-HSA-937034")
 AnnotationAssertion(Annotation(rdfs:label "Unknown kinase phosphorylates NICD4") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004672> "Reactome:R-HSA-9604606")
@@ -28411,512 +28181,6 @@ SubClassOf(<http://purl.obolibrary.org/obo/GO_0004672> <http://purl.obolibrary.o
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0004672> <http://purl.obolibrary.org/obo/GO_0016773>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0004672> <http://purl.obolibrary.org/obo/GO_0140096>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0004674> (protein serine/threonine kinase activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bf") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:2956925") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0004674> "Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.")
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0004674> "https://github.com/geneontology/go-ontology/issues/20114"^^xsd:anyURI)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_0004674> "GO:0004695")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_0004674> "GO:0004696")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_0004674> "GO:0004700")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_0004674> "GO:0106311")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "skos:exactMatch") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "EC:2.7.11.1")
-AnnotationAssertion(Annotation(rdfs:label "PDPK1 phosphorylates AKT2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-109702")
-AnnotationAssertion(Annotation(rdfs:label "MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-109822")
-AnnotationAssertion(Annotation(rdfs:label "MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-109823")
-AnnotationAssertion(Annotation(rdfs:label "MAP2K1 phosphorylates MAPK3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-109860")
-AnnotationAssertion(Annotation(rdfs:label "MAP2K2 phosphorylates MAPK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-109862")
-AnnotationAssertion(Annotation(rdfs:label "PKA phosphorylates CREB1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-111919")
-AnnotationAssertion(Annotation(rdfs:label "PKC phosphorylates GRK2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-111970")
-AnnotationAssertion(Annotation(rdfs:label "Inactivation of MAP2K1 by CDK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-112342")
-AnnotationAssertion(Annotation(rdfs:label "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-112381")
-AnnotationAssertion(Annotation(rdfs:label "PRKCB (PKC-beta) phosphorylates CARMA1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-1168635")
-AnnotationAssertion(Annotation(rdfs:label "Activated IKK phosphorylates I-kappaB") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-1168638")
-AnnotationAssertion(Annotation(rdfs:label "TAK1 associated with the CBM complex phosphorylates IKKbeta") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-1168641")
-AnnotationAssertion(Annotation(rdfs:label "ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-1181149")
-AnnotationAssertion(Annotation(rdfs:label "Type II Activin Receptor (ActRII/ACVR2) phosphorylates Type I Activin Receptor (ActRIB/ACVR1B) in response to NODAL") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-1181156")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of R-SMAD2/3 by NODAL receptor") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-1181355")
-AnnotationAssertion(Annotation(rdfs:label "Type II Activin Receptor (ActRIIB/ACVR2B) phosphorylates Type I Activin Receptor (ActRIC/ACVR1C) in response to NODAL") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-1225894")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of USP8 by P-AKT") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-1358791")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of LIN52 component of MuvB by DYRK1A") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-1362270")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of DLC2 by MAPK8") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-139908")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of BIM by JNK") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-139918")
-AnnotationAssertion(Annotation(rdfs:label "p-AKT1,p-AKT2 phosphorylates AS160 (TBC1D4)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-1445144")
-AnnotationAssertion(Annotation(rdfs:label "p-AKT2 phosphorylates Myosin 5A") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-1449597")
-AnnotationAssertion(Annotation(rdfs:label "AMPK-alpha2 phosphorylates TBC1D1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-1454699")
-AnnotationAssertion(Annotation(rdfs:label "p-AKT2 phosphorylates RGC2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-1458463")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of SMAD2,3 by Activin:Activin Receptor") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-1549526")
-AnnotationAssertion(Annotation(rdfs:label "Regulation of KIF23 (MKLP1) by phosphorylation") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-156673")
-AnnotationAssertion(Annotation(rdfs:label "Activation of Cdc25C") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-156678")
-AnnotationAssertion(Annotation(rdfs:label "PLK1 phosphorylates NUDC") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-156682")
-AnnotationAssertion(Annotation(rdfs:label "Inactivation of Wee1 kinase") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-156699")
-AnnotationAssertion(Annotation(rdfs:label "Regulation of KIF20A (MKL2) by phosphorylation") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-156723")
-AnnotationAssertion(Annotation(rdfs:label "p38 MAPK phosphorylates PPARGC1A") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-1592233")
-AnnotationAssertion(Annotation(rdfs:label "p-T309,S474-AKT2:PIP3 phosphorylates PDE3B") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-162363")
-AnnotationAssertion(Annotation(rdfs:label "Inactivation of Myt1 kinase") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-162657")
-AnnotationAssertion(Annotation(rdfs:label "Down Regulation of Emi1 through Phosphorylation of Emi1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-163010")
-AnnotationAssertion(Annotation(rdfs:label "ULK1 phosphorylates AMBRA1:BECN1 complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-1632857")
-AnnotationAssertion(Annotation(rdfs:label "hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-163416")
-AnnotationAssertion(Annotation(rdfs:label "perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-163418")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of cohesin by PLK1 at centromeres") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-1638803")
-AnnotationAssertion(Annotation(rdfs:label "LKB1 phosphorylates the alpha subunit of AMPK heterotrimer") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-164151")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of TSC2 by PKB") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-165162")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of complexed TSC2 by PKB") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-165182")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of 4E-BP1 by activated mTORC1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-165692")
-AnnotationAssertion(Annotation(rdfs:label "mTORC1 phosphorylation of RPS6KB1 (S6K)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-165718")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of Ribosomal protein S6 by activated S6K1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-165726")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation and inactivation of eEF2K by activated S6K1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-165758")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation and activation of eIF4G by activated S6K1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-165766")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation and activation of eIF4B by activated S6K1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-165777")
-AnnotationAssertion(Annotation(rdfs:label "First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-166119")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-166245")
-AnnotationAssertion(Annotation(rdfs:label "Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-166284")
-AnnotationAssertion(Annotation(rdfs:label "Multiple IRAK1 autophosphorylation steps") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-166286")
-AnnotationAssertion(Annotation(rdfs:label "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-167084")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation (Ser5) of RNA pol II CTD") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-167098")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylated MAPKs phosphorylate ATF-2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-168053")
-AnnotationAssertion(Annotation(rdfs:label "Active IKK Complex phosphorylates NF-kappa-B inhibitor") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-168140")
-AnnotationAssertion(Annotation(rdfs:label "Activated TAK1 mediates phosphorylation of the IKK Complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-168184")
-AnnotationAssertion(Annotation(rdfs:label "Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-170055")
-AnnotationAssertion(Annotation(rdfs:label "CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-170076")
-AnnotationAssertion(Annotation(rdfs:label "CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-170087")
-AnnotationAssertion(Annotation(rdfs:label "Myt-1 mediated phosphorylation of Cyclin A:Cdc2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-170116")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of Cyclin B1 in the CRS domain") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-170126")
-AnnotationAssertion(Annotation(rdfs:label "FRS2 is phosphorylated by active TrkA receptor") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-170977")
-AnnotationAssertion(Annotation(rdfs:label "Free APC/C phosphorylated by Plk1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-174119")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of the Emi1 DSGxxS degron by Plk1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-174174")
-AnnotationAssertion(Annotation(rdfs:label "Recruitment and activation of Chk1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-176116")
-AnnotationAssertion(Annotation(rdfs:label "Activation of claspin") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-176298")
-AnnotationAssertion(Annotation(rdfs:label "p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-187688")
-AnnotationAssertion(Annotation(rdfs:label "CAK-mediated phosphorylation of Cyclin A:Cdk2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-187949")
-AnnotationAssertion(Annotation(rdfs:label "CAK-mediated phosphorylation of Cyclin E:Cdk2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-188350")
-AnnotationAssertion(Annotation(rdfs:label "IRAK is activated") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-193647")
-AnnotationAssertion(Annotation(rdfs:label "IKKbeta phosphorylates IkB causing NF-kB to dissociate") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-193705")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of APC component of the destruction complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-195275")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-195283")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-195287")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-195300")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of beta-catenin at Ser45 by CK1 alpha") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-195318")
-AnnotationAssertion(Annotation(rdfs:label "PDPK1 phosphorylates AKT at T308") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-198270")
-AnnotationAssertion(Annotation(rdfs:label "AKT phosphorylates BAD") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-198347")
-AnnotationAssertion(Annotation(rdfs:label "AKT phosphorylates GSK3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-198371")
-AnnotationAssertion(Annotation(rdfs:label "AKT phosphorylates MDM2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-198599")
-AnnotationAssertion(Annotation(rdfs:label "AKT phosphorylates TSC2, inhibiting it") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-198609")
-AnnotationAssertion(Annotation(rdfs:label "AKT phosphorylates IKKalpha") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-198611")
-AnnotationAssertion(Annotation(rdfs:label "AKT phosphorylates p21Cip1 and p27Kip1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-198613")
-AnnotationAssertion(Annotation(rdfs:label "AKT phosphorylates caspase-9") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-198621")
-AnnotationAssertion(Annotation(rdfs:label "TORC2 (mTOR) phosphorylates AKT at S473") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-198640")
-AnnotationAssertion(Annotation(rdfs:label "p38MAPK phosphorylates MSK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-198669")
-AnnotationAssertion(Annotation(rdfs:label "ERK1/2 activates ELK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-198731")
-AnnotationAssertion(Annotation(rdfs:label "ERK1/2/5 activate RSK1/2/3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-198746")
-AnnotationAssertion(Annotation(rdfs:label "ERK1/2 phosphorylates MSK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-198756")
-AnnotationAssertion(Annotation(rdfs:label "AKT phosphorylates CREB1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-199298")
-AnnotationAssertion(Annotation(rdfs:label "AKT phosphorylates FOXO transcription factors") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-199299")
-AnnotationAssertion(Annotation(rdfs:label "AKT can phosphorylate RSK") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-199839")
-AnnotationAssertion(Annotation(rdfs:label "AKT can phosphorylate NR4A1 (NUR77)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-199863")
-AnnotationAssertion(Annotation(rdfs:label "RSK1/2/3 phosphorylates CREB at Serine 133") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-199895")
-AnnotationAssertion(Annotation(rdfs:label "MSK1 activates ATF1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-199910")
-AnnotationAssertion(Annotation(rdfs:label "MAPKAPK2 phosphorylates CREB at Serine 133") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-199917")
-AnnotationAssertion(Annotation(rdfs:label "ERK5 activates the transcription factor MEF2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-199929")
-AnnotationAssertion(Annotation(rdfs:label "MSK1 activates CREB") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-199935")
-AnnotationAssertion(Annotation(rdfs:label "AKT phosphorylates AKT1S1 (PRAS40)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-200143")
-AnnotationAssertion(Annotation(rdfs:label "Activation of cytosolic AMPK by phosphorylation") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-200421")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-201677")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of LRP5/6 cytoplasmic domain by CSNKI") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-201691")
-AnnotationAssertion(Annotation(rdfs:label "CSNK2-mediated phosphorylation of DVL") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-201717")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of PKC theta") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-202222")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of CARMA1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-202437")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of Bcl10") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-202459")
-AnnotationAssertion(Annotation(rdfs:label "Activation of IKK complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-202500")
-AnnotationAssertion(Annotation(rdfs:label "Activation of TAK1-TAB2 complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-202510")
-AnnotationAssertion(Annotation(rdfs:label "p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-202541")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of STK4 (MST1) and SAV1 by STK4") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2028284")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2028555")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of YAP by LATS2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2028583")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2028589")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of STK3 (MST2) and SAV1 by STK3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2028591")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of YAP by LATS1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2028598")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of MOB1A and B by p-STK4 (p-MST1)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2028629")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of MOB1A and B by p-STK3 (p-MST2)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2028635")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of WWTR1 (TAZ) by LATS2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2028661")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of MOB1A and B by p-STK4(MST1)/N") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2028670")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2028673")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of MOB1A and B by p-STK3(MST2)/N") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2028675")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2028679")
-AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of PAK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2029454")
-AnnotationAssertion(Annotation(rdfs:label "PAK1 phosphorylates LIMK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2029460")
-AnnotationAssertion(Annotation(rdfs:label "p-ERK phosphorylates WAVEs and ABI") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2029469")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of WWTR1 (TAZ) by LATS1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2060328")
-AnnotationAssertion(Annotation(rdfs:label "IKBA is phosphorylated by Phospho IKKB kinase") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-209087")
-AnnotationAssertion(Annotation(rdfs:label "AKT phosphorylates FOXO1A") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-211164")
-AnnotationAssertion(Annotation(rdfs:label "Partial autophosphorylation of PAK-2 at  Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-211583")
-AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of PAK-2p34 in the activation loop") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-211650")
-AnnotationAssertion(Annotation(rdfs:label "MASTL (GWL) phosphorylates ARPP19") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2168079")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2176475")
-AnnotationAssertion(Annotation(rdfs:label "PLK1 phosphorylates GORASP1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2214351")
-AnnotationAssertion(Annotation(rdfs:label "AKT1 E17K mutant is phosphorylated by TORC2 complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2243938")
-AnnotationAssertion(Annotation(rdfs:label "PDPK1 phosphorylates AKT1 E17K mutant") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2243942")
-AnnotationAssertion(Annotation(rdfs:label "PLK1 hyperphosphorylates Condensin II complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2294580")
-AnnotationAssertion(Annotation(rdfs:label "IRF3 is phosphorylated by TBK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2396007")
-AnnotationAssertion(Annotation(rdfs:label "AKT1 E17K mutant phosphorylates BAD") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2399941")
-AnnotationAssertion(Annotation(rdfs:label "AKT1 E17K mutant phosphorylates GSK3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2399966")
-AnnotationAssertion(Annotation(rdfs:label "AKT1 E17K mutant phosphorylates p21Cip1 and p27Kip1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2399969")
-AnnotationAssertion(Annotation(rdfs:label "AKT1 E17K mutant phosphorylates AKT1S1 (PRAS40)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2399977")
-AnnotationAssertion(Annotation(rdfs:label "AKT1 E17K mutant phosphorylates MDM2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2399981")
-AnnotationAssertion(Annotation(rdfs:label "AKT1 E17K mutant phosphorylates TSC2, inhibiting it") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2399982")
-AnnotationAssertion(Annotation(rdfs:label "AKT1 E17K mutant phosphorylates caspase-9") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2399985")
-AnnotationAssertion(Annotation(rdfs:label "AKT1 E17K mutant phosphorylates NR4A1 (NUR77)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2399988")
-AnnotationAssertion(Annotation(rdfs:label "AKT1 E17K mutant phosphorylates forkhead box transcription factors") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2399992")
-AnnotationAssertion(Annotation(rdfs:label "AKT1 E17K mutant phosphorylates CREB1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2399996")
-AnnotationAssertion(Annotation(rdfs:label "AKT1 E17K mutant phosphorylates RSK") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2399999")
-AnnotationAssertion(Annotation(rdfs:label "AKT1 E17K mutant phosphorylates CHUK (IKKalpha)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2400001")
-AnnotationAssertion(Annotation(rdfs:label "MAPK3-3 or MAPK1 phosphorylate GORASP2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2422927")
-AnnotationAssertion(Annotation(rdfs:label "MASTL phosphorylates ENSA") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2430535")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of cohesin by PLK1 at chromosomal arms") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2466068")
-AnnotationAssertion(Annotation(rdfs:label "ACVR2A,B (ActRIIA,B) phosphorylates ACVR1C (ActRIC, ALK7) in response to Activin") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2470508")
-AnnotationAssertion(Annotation(rdfs:label "CK2 phosphorylates condensin I subunits") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2529020")
-AnnotationAssertion(Annotation(rdfs:label "PLK1 phosphorylates OPTN") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2562526")
-AnnotationAssertion(Annotation(rdfs:label "AJUBA facilitates AURKA autophosphorylation") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2574840")
-AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of PAK") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2730856")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of MEK7 by MEKK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2730868")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of IKK-beta by TAK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2730876")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of MEK4 by MEKK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2730896")
-AnnotationAssertion(Annotation(rdfs:label "Activation of TAK1 complex bound to pUb-TRAF6") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2730900")
-AnnotationAssertion(Annotation(rdfs:label "PLK1 phosphorylates NEK9") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2984226")
-AnnotationAssertion(Annotation(rdfs:label "NEK9 phosphorylates NEK6/NEK7") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2984258")
-AnnotationAssertion(Annotation(rdfs:label "NEK6/NEK7 phosphorylates NUP98") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2990880")
-AnnotationAssertion(Annotation(rdfs:label "VRK1/VRK2 phosphorylate BANF1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-2993898")
-AnnotationAssertion(Annotation(rdfs:label "AURKA phosphorylates PLK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3000310")
-AnnotationAssertion(Annotation(rdfs:label "PLK1 phosphorylates BORA") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3000327")
-AnnotationAssertion(Annotation(rdfs:label "MAPKs phosphorylate ETS1 and ETS2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3132737")
-AnnotationAssertion(Annotation(rdfs:label "Activated ERKs phosphorylate ERF") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3209160")
-AnnotationAssertion(Annotation(rdfs:label "STK11 (LKB1) phosphorylates NUAK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3222006")
-AnnotationAssertion(Annotation(rdfs:label "NUAK1 phosphorylates TP53") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3222020")
-AnnotationAssertion(Annotation(rdfs:label "MAP3K5 phosphorylates MKK3 and MKK6") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3228469")
-AnnotationAssertion(Annotation(rdfs:label "p-MAPKAPK3 phosphorylates BMI1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3229102")
-AnnotationAssertion(Annotation(rdfs:label "MAP3K5 (ASK1) phosphorylates MAP2K4 (SEK1)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3229152")
-AnnotationAssertion(Annotation(rdfs:label "MAPKAPK5 phosphorylates TP53") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3239014")
-AnnotationAssertion(Annotation(rdfs:label "Active p38 MAPK phosphorylates MAPKAPK5") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3239019")
-AnnotationAssertion(Annotation(rdfs:label "TBK1 phosphorylates STAT6 at Ser407") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3249371")
-AnnotationAssertion(Annotation(rdfs:label "Constitutive phosphorylation by GSK3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3371435")
-AnnotationAssertion(Annotation(rdfs:label "Constitutive phosphorylation  by pERK1/2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3371531")
-AnnotationAssertion(Annotation(rdfs:label "DBC1 is phosphorylated by ATM/ART") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3371567")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of MDM4 by CHEK2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-349426")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of COP1 at Ser-387  by ATM") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-349444")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of MDM4 by ATM") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-349455")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of L1 by p90rsk") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-374696")
-AnnotationAssertion(Annotation(rdfs:label "AKT phosphorylates CBY1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3769394")
-AnnotationAssertion(Annotation(rdfs:label "Activated Akt1 phosphorylates AKT1S1 (PRAS40)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-377186")
-AnnotationAssertion(Annotation(rdfs:label "WNT signaling stimulates CSNK1-dependent phosphorylation of DVL") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3772435")
-AnnotationAssertion(Annotation(rdfs:label "Plk1-mediated phosphorylation of Nlp") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-380272")
-AnnotationAssertion(Annotation(rdfs:label "IRE1 dimer autophosphorylates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-381091")
-AnnotationAssertion(Annotation(rdfs:label "EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-381111")
-AnnotationAssertion(Annotation(rdfs:label "RPS6KA1/2/3 phosphorylates CEBPB on S321") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3857328")
-AnnotationAssertion(Annotation(rdfs:label "MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3857329")
-AnnotationAssertion(Annotation(rdfs:label "WNT-dependent phosphorylation of DVL") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3858480")
-AnnotationAssertion(Annotation(rdfs:label "AKT interacts and phosphorylates Cot") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-389756")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of L1 by CK-II") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-392752")
-AnnotationAssertion(Annotation(rdfs:label "ROCK phosphorylates LIMK1,2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3928577")
-AnnotationAssertion(Annotation(rdfs:label "LIMK phosphorylates CFL1, inactivating it") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3928608")
-AnnotationAssertion(Annotation(rdfs:label "Activated ROCK phosphorylates MRLCs") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3928616")
-AnnotationAssertion(Annotation(rdfs:label "PAK1 autophosphorylates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3928620")
-AnnotationAssertion(Annotation(rdfs:label "PAKs autophosphorylate") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3928625")
-AnnotationAssertion(Annotation(rdfs:label "PAKs phosphorylate MLC") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-3928640")
-AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of PAK") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-399939")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of CRMPs by Cdk5") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-399944")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of cofilin by LIMK-1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-399950")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of CRMPs by GSK3beta") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-399951")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of LIMK-1 by PAK") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-399952")
-AnnotationAssertion(Annotation(rdfs:label "Protein kinase C, alpha type phosphorylates MARCKS") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-399978")
-AnnotationAssertion(Annotation(rdfs:label "CSNK1E,CSNK1D phosphorylate CRY and PER proteins") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-400382")
-AnnotationAssertion(Annotation(rdfs:label "PLK1 phosphorylates FOXM1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-4088134")
-AnnotationAssertion(Annotation(rdfs:label "Myosin phosphatase inactivation by ROCK") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-419083")
-AnnotationAssertion(Annotation(rdfs:label "LIM kinase phosphorylation by ROCK") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-419087")
-AnnotationAssertion(Annotation(rdfs:label "Myosin regulatory light chain phosphorylation by ROCK") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-419197")
-AnnotationAssertion(Annotation(rdfs:label "Transphosphorylation of pLIMK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-419644")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of cPLA2 by MAPK p38 alpha") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-428961")
-AnnotationAssertion(Annotation(rdfs:label "ALOX5 is phosphorylated by MAPKAP2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-429016")
-AnnotationAssertion(Annotation(rdfs:label "monophospho-CERT + 2 ATP => multiphospho-CERT + 2 ADP") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-429714")
-AnnotationAssertion(Annotation(rdfs:label "Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-432110")
-AnnotationAssertion(Annotation(rdfs:label "Dissociation of CaM and CAMK2 autophosphorylation") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-4332358")
-AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation and activation of CAMK2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-4332363")
-AnnotationAssertion(Annotation(rdfs:label "Activation of MAP3K7 in response to WNT") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-4332388")
-AnnotationAssertion(Annotation(rdfs:label "NLK phosphorylates TCF/LEF") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-4411383")
-AnnotationAssertion(Annotation(rdfs:label "Activation of NLK") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-4411402")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-442724")
-AnnotationAssertion(Annotation(rdfs:label "PDPK1 phosphorylates RSKs") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-442739")
-AnnotationAssertion(Annotation(rdfs:label "PAK phosphorylates cortactin") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-442832")
-AnnotationAssertion(Annotation(rdfs:label "Interaction of PAK1 with Rac1-GTP") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-445072")
-AnnotationAssertion(Annotation(rdfs:label "IRAK4 phosphorylates IRAK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-446694")
-AnnotationAssertion(Annotation(rdfs:label "IRAK4-activated IRAK1 autophosphorylates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-446701")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of E proteins by p38 MAPK") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-448948")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of MEF2 proteins by p38") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-448955")
-AnnotationAssertion(Annotation(rdfs:label "Active p38 MAPK phosphorylates MAPKAPK2 or 3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-450222")
-AnnotationAssertion(Annotation(rdfs:label "c-FOS activation by phospho ERK1/2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-450325")
-AnnotationAssertion(Annotation(rdfs:label "Activated TAK1 phosphorylates MKK4/MKK7") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-450337")
-AnnotationAssertion(Annotation(rdfs:label "activated human TAK1 phosphorylates MKK3/MKK6") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-450346")
-AnnotationAssertion(Annotation(rdfs:label "MK2 phosphorylates ZFP36 (Tristetraproline, TTP)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-450463")
-AnnotationAssertion(Annotation(rdfs:label "MK2 phosphorylates BRF1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-450474")
-AnnotationAssertion(Annotation(rdfs:label "Protein Kinase B/Akt phosphorylates BRF1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-450490")
-AnnotationAssertion(Annotation(rdfs:label "Protein Kinase B (AKT) phosphorylates KSRP") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-450499")
-AnnotationAssertion(Annotation(rdfs:label "hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2.") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-450827")
-AnnotationAssertion(Annotation(rdfs:label "MAP kinase p38 phosphorylates KSRP") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-451152")
-AnnotationAssertion(Annotation(rdfs:label "Activation of JNK by DSCAM") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-451347")
-AnnotationAssertion(Annotation(rdfs:label "VANGL2 is phosphorylated in response to WNT5A") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-4551570")
-AnnotationAssertion(Annotation(rdfs:label "DVL2 is phosphorylated after WNT5A binding to FZD") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-4608825")
-AnnotationAssertion(Annotation(rdfs:label "MAPKAPK2 phosphorylates HSF1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-4793911")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of HSF1 at Ser230 induces transactivation") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5082387")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of HSF1 at Ser326 induces transactivation") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5082405")
-AnnotationAssertion(Annotation(rdfs:label "RIPK1 is phosphorylated") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5213464")
-AnnotationAssertion(Annotation(rdfs:label "RIPK3 is phosphorylated") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5213466")
-AnnotationAssertion(Annotation(rdfs:label "PAK2 autophorylates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5218814")
-AnnotationAssertion(Annotation(rdfs:label "PDK1 phosphorylates PKC") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5218821")
-AnnotationAssertion(Annotation(rdfs:label "Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5218826")
-AnnotationAssertion(Annotation(rdfs:label "p-Y420-FYN is phosphorylated on S21") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5218854")
-AnnotationAssertion(Annotation(rdfs:label "RIPK3 phosphorylates MLKL") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5218906")
-AnnotationAssertion(Annotation(rdfs:label "p-MAPK2/3 phosphorylates HSP27") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5218916")
-AnnotationAssertion(Annotation(rdfs:label "NFKBIA variant is not phosphorylated within IkBA:NF-kappaB") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5228811")
-AnnotationAssertion(Annotation(rdfs:label "AXIN is phosphorylated in the destruction complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5229343")
-AnnotationAssertion(Annotation(rdfs:label "p-AKT2 phosphorylates C2CD5") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5260201")
-AnnotationAssertion(Annotation(rdfs:label "PAK1-3 autophosphorylates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5357472")
-AnnotationAssertion(Annotation(rdfs:label "PAK1-3 phosphorylates VE-cadherin") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5357477")
-AnnotationAssertion(Annotation(rdfs:label "CHUK, IKBKB phosphorylate CYLD at S418") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5357831")
-AnnotationAssertion(Annotation(rdfs:label "DMPK phosphorylates PLN") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5578777")
-AnnotationAssertion(Annotation(rdfs:label "Active NIK phosphorylates IKKA dimer") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5607722")
-AnnotationAssertion(Annotation(rdfs:label "Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5607726")
-AnnotationAssertion(Annotation(rdfs:label "K63polyUb-TAK1 autophosphorylates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5607732")
-AnnotationAssertion(Annotation(rdfs:label "K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5607742")
-AnnotationAssertion(Annotation(rdfs:label "CK1 phosphorylates p-GLI2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5610718")
-AnnotationAssertion(Annotation(rdfs:label "CK1 phosphorylates p-GLI3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5610722")
-AnnotationAssertion(Annotation(rdfs:label "GSK3 phosphorylates p-GLI2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5610730")
-AnnotationAssertion(Annotation(rdfs:label "GSK3 phosphorylates p-GLI3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5610732")
-AnnotationAssertion(Annotation(rdfs:label "Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5624473")
-AnnotationAssertion(Annotation(rdfs:label "PAK phosphorylates p21 RAF1 on S338") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5624492")
-AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of PAK1,2,3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5627775")
-AnnotationAssertion(Annotation(rdfs:label "CSNK1A1 phosphorylates SMO dimer") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5632670")
-AnnotationAssertion(Annotation(rdfs:label "ADRBK1 phosphorylates SMO dimer") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5632672")
-AnnotationAssertion(Annotation(rdfs:label "GLI proteins are phosphorylated") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5635841")
-AnnotationAssertion(Annotation(rdfs:label "ULK3 phosphorylates GLI") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5635842")
-AnnotationAssertion(Annotation(rdfs:label "AMPK (complex) phosphorylates ULK1 (complex)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5665868")
-AnnotationAssertion(Annotation(rdfs:label "AURKB phosphorylates DIAPH2-2 at kinetochores") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5666160")
-AnnotationAssertion(Annotation(rdfs:label "NIK autophosphorylates on T559") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5668545")
-AnnotationAssertion(Annotation(rdfs:label "PAK2 phosphorylates myosin regulatory light chain (MRLC)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5668932")
-AnnotationAssertion(Annotation(rdfs:label "PAK1 phosphorylates myosin phosphatase") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5668947")
-AnnotationAssertion(Annotation(rdfs:label "PAK1 or PAK2 phosphorylates MYLK") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5668984")
-AnnotationAssertion(Annotation(rdfs:label "PAK1 phosphorylates FLNA") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5669250")
-AnnotationAssertion(Annotation(rdfs:label "p-T774-PKN1 phosphorylates PPP1R14A") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5671763")
-AnnotationAssertion(Annotation(rdfs:label "Activated CIT phosphorylates MRLCs") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5671919")
-AnnotationAssertion(Annotation(rdfs:label "Thr-180 of ULK1 is phosphorylated") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5672008")
-AnnotationAssertion(Annotation(rdfs:label "Active MTORC1 phosphorylates ULK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5672010")
-AnnotationAssertion(Annotation(rdfs:label "mTORC1 phosphorylates AKT1S1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5672828")
-AnnotationAssertion(Annotation(rdfs:label "MARK3 phosphorylates KSR1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5672948")
-AnnotationAssertion(Annotation(rdfs:label "MAP2Ks phosphorylate MAPKs") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5672973")
-AnnotationAssertion(Annotation(rdfs:label "RAF phosphorylates MAP2K dimer") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5672978")
-AnnotationAssertion(Annotation(rdfs:label "Activated MAPKs phosphorylate MAP2K1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5674496")
-AnnotationAssertion(Annotation(rdfs:label "Activated MAPK phosphorylates RAF1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5675194")
-AnnotationAssertion(Annotation(rdfs:label "Activated MAPKs phosphorylate BRAF") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5675198")
-AnnotationAssertion(Annotation(rdfs:label "ULK1 phosphorylates ATG13 and RB1CC1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5675868")
-AnnotationAssertion(Annotation(rdfs:label "ULK1 phosphorylates Beclin-1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5679205")
-AnnotationAssertion(Annotation(rdfs:label "MRN bound to shortened telomeres activates ATM") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5682026")
-AnnotationAssertion(Annotation(rdfs:label "PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5682101")
-AnnotationAssertion(Annotation(rdfs:label "ATM phosphorylates HERC2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5682598")
-AnnotationAssertion(Annotation(rdfs:label "ATM phosphorylates WHSC1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5682983")
-AnnotationAssertion(Annotation(rdfs:label "ATM phosphorylates TP53BP1 at DNA DSBs") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5683425")
-AnnotationAssertion(Annotation(rdfs:label "p-T68-CHEK2 autophosphorylates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5683792")
-AnnotationAssertion(Annotation(rdfs:label "CHEK2 phosphorylates BRCA1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5683801")
-AnnotationAssertion(Annotation(rdfs:label "ATM phosphorylates EYA1-4") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5683964")
-AnnotationAssertion(Annotation(rdfs:label "CDK2 phosphorylates RBBP8") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5684096")
-AnnotationAssertion(Annotation(rdfs:label "ATM phosphorylates RBBP8") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5684140")
-AnnotationAssertion(Annotation(rdfs:label "Activation of CHEK1 at resected DNA DSBs") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5684887")
-AnnotationAssertion(Annotation(rdfs:label "ATR phosphorylates RPA2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5685156")
-AnnotationAssertion(Annotation(rdfs:label "CHEK1 phosphorylates RAD51") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5685230")
-AnnotationAssertion(Annotation(rdfs:label "CHEK1 phosphorylates BRCA2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5685242")
-AnnotationAssertion(Annotation(rdfs:label "Activated ATM phosphorylates ABL1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5686578")
-AnnotationAssertion(Annotation(rdfs:label "Activated ATM phosphorylates DCLRE1C") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5686704")
-AnnotationAssertion(Annotation(rdfs:label "PAK1,2,3 phosphorylates MAPK6,4") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5687086")
-AnnotationAssertion(Annotation(rdfs:label "p-S MAPK6 phosphorylates NCOA3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5687090")
-AnnotationAssertion(Annotation(rdfs:label "p-S MAPK6,4 phosphorylate MAPKAPK5") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5687094")
-AnnotationAssertion(Annotation(rdfs:label "p-T182 MAPKAPK5 phosphorylates FOXO3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5687101")
-AnnotationAssertion(Annotation(rdfs:label "p-S MAPKAPK5 phosphorylates HSPB1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5687121")
-AnnotationAssertion(Annotation(rdfs:label "PRKDC phosphorylates DCLRE1C at DNA DSBs") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5687183")
-AnnotationAssertion(Annotation(rdfs:label "p-T182-MAPKAPK5 phoshphorylates DNAJB1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5690250")
-AnnotationAssertion(Annotation(rdfs:label "MAPKAPK5 phosphorylates KALRN") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5692768")
-AnnotationAssertion(Annotation(rdfs:label "SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5692775")
-AnnotationAssertion(Annotation(rdfs:label "p-S182 MAPKAPK5 phosphorylates FOXO1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5692779")
-AnnotationAssertion(Annotation(rdfs:label "ATM phosphorylates MDC1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5693536")
-AnnotationAssertion(Annotation(rdfs:label "MRN activates ATM") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5693540")
-AnnotationAssertion(Annotation(rdfs:label "ATM phosphorylates histone H2AFX on S139 at DNA DSBs") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5693549")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of BRCA1-A complex at multiple sites by ATM") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5693551")
-AnnotationAssertion(Annotation(rdfs:label "DNA-PKcs autophosphorylates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5693575")
-AnnotationAssertion(Annotation(rdfs:label "ATM phosphorylates NBN") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5693598")
-AnnotationAssertion(Annotation(rdfs:label "ATM phosphorylates TP53 at S15") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5693609")
-AnnotationAssertion(Annotation(rdfs:label "CSNK1D phosphorylates SEC23") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-5694441")
-AnnotationAssertion(Annotation(rdfs:label "ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6788392")
-AnnotationAssertion(Annotation(rdfs:label "TORC2 complex phosphorylates SGK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6795290")
-AnnotationAssertion(Annotation(rdfs:label "SGK1 phosphorylates MDM2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6795460")
-AnnotationAssertion(Annotation(rdfs:label "PDPK1 phosphorylates SGK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6795473")
-AnnotationAssertion(Annotation(rdfs:label "ATM phosphorylates DYRK2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6798372")
-AnnotationAssertion(Annotation(rdfs:label "DYRK2 phosphorylates TP53") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6798374")
-AnnotationAssertion(Annotation(rdfs:label "ATM phosphorylates ZNF420") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6799097")
-AnnotationAssertion(Annotation(rdfs:label "CHEK1 phosphorylates TP53") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6799246")
-AnnotationAssertion(Annotation(rdfs:label "ATR phosphorylates TP53") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6799332")
-AnnotationAssertion(Annotation(rdfs:label "HIPK2 phosphorylates TP53") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6799409")
-AnnotationAssertion(Annotation(rdfs:label "ATM phosphorylates PIDD1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6800490")
-AnnotationAssertion(Annotation(rdfs:label "PLK2 phosphorylates CENPJ") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6801666")
-AnnotationAssertion(Annotation(rdfs:label "PLK2 phosphorylates NPM1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6801675")
-AnnotationAssertion(Annotation(rdfs:label "High kinase activity BRAF complexes phosphorylate MAP2Ks") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6802911")
-AnnotationAssertion(Annotation(rdfs:label "RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6802919")
-AnnotationAssertion(Annotation(rdfs:label "Mutant RAS:p-RAF complexes phosphorylate MAP2Ks") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6802926")
-AnnotationAssertion(Annotation(rdfs:label "p-BRAF and RAF fusion dimers phosphorylate MAP2Ks") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6802933")
-AnnotationAssertion(Annotation(rdfs:label "MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6802935")
-AnnotationAssertion(Annotation(rdfs:label "RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6802943")
-AnnotationAssertion(Annotation(rdfs:label "PLK3 phosphorylates CDC25C") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6802973")
-AnnotationAssertion(Annotation(rdfs:label "CHEK2 phosphorylates TTC5") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6804266")
-AnnotationAssertion(Annotation(rdfs:label "ATM phosphorylates TTC5") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6804276")
-AnnotationAssertion(Annotation(rdfs:label "ATM phosphorylates MDM2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6804955")
-AnnotationAssertion(Annotation(rdfs:label "CK2:FACT phosphorylates TP53") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6805059")
-AnnotationAssertion(Annotation(rdfs:label "AURKA phosphorylates TP53") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6805103")
-AnnotationAssertion(Annotation(rdfs:label "AURKB phosphorylates TP53") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6805126")
-AnnotationAssertion(Annotation(rdfs:label "CDK5 phosphorylates TP53") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6805276")
-AnnotationAssertion(Annotation(rdfs:label "PLK3 phosphorylates TP53") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6805285")
-AnnotationAssertion(Annotation(rdfs:label "TAF1 phosphorylates TP53") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6805399")
-AnnotationAssertion(Annotation(rdfs:label "TP53RK phosphorylates TP53") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6805479")
-AnnotationAssertion(Annotation(rdfs:label "AKT phosphorylates KAT6A") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6805640")
-AnnotationAssertion(Annotation(rdfs:label "AKT phosphorylates PHF20") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6805785")
-AnnotationAssertion(Annotation(rdfs:label "CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6810233")
-AnnotationAssertion(Annotation(rdfs:label "MAPKs phosphorylate PP2A") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6811454")
-AnnotationAssertion(Annotation(rdfs:label "CK2 phosphorylates PDCL") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-6814409")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of Cdc25A at Ser-123 by Chk1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-69604")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of Cdc25A at Ser-123 by Chk2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-69608")
-AnnotationAssertion(Annotation(rdfs:label "CHEK2 phosphorylates TP53") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-69685")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation and activation of CHEK2 by ATM") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-69891")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of Cdc25C at Ser 216 by Chk1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-75010")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of Wee1 kinase by Chk1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-75028")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of Cdc25C at Ser216 by CHEK2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-75809")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-75820")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation (Ser5) of RNA pol II CTD") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-77071")
-AnnotationAssertion(Annotation(rdfs:label "Casein kinase II phosphorylates PTEN") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8850945")
-AnnotationAssertion(Annotation(rdfs:label "Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8852306")
-AnnotationAssertion(Annotation(rdfs:label "PLK1 phosphorylates GTSE1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8852317")
-AnnotationAssertion(Annotation(rdfs:label "TPX2 promotes AURKA autophosphorylation") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8853419")
-AnnotationAssertion(Annotation(rdfs:label "AURKA phosphorylates PHLDA1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8853444")
-AnnotationAssertion(Annotation(rdfs:label "PKA phosphorylates RET:GDNF:GFRA dimer") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8854908")
-AnnotationAssertion(Annotation(rdfs:label "AAK1 phosphorylates AP-2 mu subunit at T156") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8856813")
-AnnotationAssertion(Annotation(rdfs:label "p25-bound CDK5 phosphorylates CDC25B") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8863007")
-AnnotationAssertion(Annotation(rdfs:label "p25-bound CDK5 phosphorylates CDC25C") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8863011")
-AnnotationAssertion(Annotation(rdfs:label "p25-bound CDK5 phosphorylates CDC25A") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8863014")
-AnnotationAssertion(Annotation(rdfs:label "IKKB phosphorylates SNAP23") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8863895")
-AnnotationAssertion(Annotation(rdfs:label "MAPK12 phosphorylates PTPN3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8868118")
-AnnotationAssertion(Annotation(rdfs:label "CDK5:p25 phosphorylates GOLGA2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8868260")
-AnnotationAssertion(Annotation(rdfs:label "CDK5:p25 phosphorylates lamin B1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8868340")
-AnnotationAssertion(Annotation(rdfs:label "CDK5:p25 phosphorylates lamin A") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8868344")
-AnnotationAssertion(Annotation(rdfs:label "CDK5:p25 phosphorylates PRDX1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8868567")
-AnnotationAssertion(Annotation(rdfs:label "CDK5:p25 phosphorylates PRDX2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8868573")
-AnnotationAssertion(Annotation(rdfs:label "CDK5:p25 phosphorylates JUN") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8868666")
-AnnotationAssertion(Annotation(rdfs:label "CDK5:p25 phosphorylates FOXO3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8870558")
-AnnotationAssertion(Annotation(rdfs:label "Casein kinase II phosphorylates STARD10") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8873929")
-AnnotationAssertion(Annotation(rdfs:label "p-ULK1 phosphorylates DENND3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8876446")
-AnnotationAssertion(Annotation(rdfs:label "MAP2K6 phosphorylates PIP4K2B") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8877691")
-AnnotationAssertion(Annotation(rdfs:label "HIPK2 phosphorylates RUNX1 and EP300") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8878050")
-AnnotationAssertion(Annotation(rdfs:label "HIPK2 phosphorylates RUNX1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8878054")
-AnnotationAssertion(Annotation(rdfs:label "CK2 phosphorylates NFE2L2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8932322")
-AnnotationAssertion(Annotation(rdfs:label "Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8933446")
-AnnotationAssertion(Annotation(rdfs:label "Activated AKT phosphorylates RUNX2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8939963")
-AnnotationAssertion(Annotation(rdfs:label "CDK1 phosphorylates VCPIP1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8940100")
-AnnotationAssertion(Annotation(rdfs:label "CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8942836")
-AnnotationAssertion(Annotation(rdfs:label "mTORC1 phosphorylates MAF1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8944454")
-AnnotationAssertion(Annotation(rdfs:label "FUNDC1 is phosphorylated by CK2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8948039")
-AnnotationAssertion(Annotation(rdfs:label "FUNDC1 is phosphorylated by ULK1 at Ser17") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8948146")
-AnnotationAssertion(Annotation(rdfs:label "AKT phosphorylates MKRN1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8948757")
-AnnotationAssertion(Annotation(rdfs:label "FAM20C phosphorylates FAM20C substrates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-8952289")
-AnnotationAssertion(Annotation(rdfs:label "CHEK1 phosphorylates E2F6") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9007539")
-AnnotationAssertion(Annotation(rdfs:label "GSK3B phosphorylates RUNX2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9008480")
-AnnotationAssertion(Annotation(rdfs:label "PPM1D dephosphorylates RUNX2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9008822")
-AnnotationAssertion(Annotation(rdfs:label "Activated ERKs phosphorylate RUNX2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9009208")
-AnnotationAssertion(Annotation(rdfs:label "p-TEFb phosphorylates serine 2 in RNA polymerase II CTD") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9012319")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of IRF-3/IRF7 and their release from the activated TLR3 complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9013978")
-AnnotationAssertion(Annotation(rdfs:label "HIPK2 phosphorylates MECP2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9022314")
-AnnotationAssertion(Annotation(rdfs:label "AURKB phosphorylates MECP2 at S423") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9023132")
-AnnotationAssertion(Annotation(rdfs:label "Estrogen-independent phosphorylation of ESR1 S118 by MAPK1 and MAPK3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9032751")
-AnnotationAssertion(Annotation(rdfs:label "CDK5 phosphorylates NTRK2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9032863")
-AnnotationAssertion(Annotation(rdfs:label "ATR phosphorylates Histone H2A.X at unsynapsed regions") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-912470")
-AnnotationAssertion(Annotation(rdfs:label "PKA/PKG phosphorylate Rap1GAP2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-913996")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation and release of IRF3/IRF7") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-918229")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation and release of IRF7") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-933525")
-AnnotationAssertion(Annotation(rdfs:label "SPRY2 is phosphorylated by phosphorylated MNK1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-934559")
-AnnotationAssertion(Annotation(rdfs:label "Activation of TAK1 complex bound to activated TLR4 complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-936951")
-AnnotationAssertion(Annotation(rdfs:label "IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-937022")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-937059")
-AnnotationAssertion(Annotation(rdfs:label "AKT1 phosphorylates NOTCH4") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9604328")
-AnnotationAssertion(Annotation(rdfs:label "Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9610153")
-AnnotationAssertion(Annotation(rdfs:label "MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9610156")
-AnnotationAssertion(Annotation(rdfs:label "BRAF autophosphorylates downstream of RAP1 and NGF") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9610163")
-AnnotationAssertion(Annotation(rdfs:label "SGK phosphorylates CREB1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9612501")
-AnnotationAssertion(Annotation(rdfs:label "SGK phosphorylates SRF") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9612509")
-AnnotationAssertion(Annotation(rdfs:label "BRAF in Rap1-GTP complex:BRAF complex autophosphorylates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9612980")
-AnnotationAssertion(Annotation(rdfs:label "PRKAA2 phosphorylates PLINs") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9613530")
-AnnotationAssertion(Annotation(rdfs:label "AMPK phosphorylates MAPT") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9619515")
-AnnotationAssertion(Annotation(rdfs:label "ERKs phosphorylate RSKs") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9619843")
-AnnotationAssertion(Annotation(rdfs:label "RSKs autophosphorylate") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9620004")
-AnnotationAssertion(Annotation(rdfs:label "AKT phosphorylates FOXO3 downstream of ESR1 and EGFR") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9624526")
-AnnotationAssertion(Annotation(rdfs:label "MAPK11 or MAPK14 phosphorylates NCF1 at Ser345") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9626880")
-AnnotationAssertion(Annotation(rdfs:label "CASP9 is phosphorylated at T125") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9627089")
-AnnotationAssertion(Annotation(rdfs:label "CDKN1B is phosphorylated in response to estrogen") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9632868")
-AnnotationAssertion(Annotation(rdfs:label "p-T899-EIF2AK4 (GCN2) phosphorylates EIF2AS1") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9633008")
-AnnotationAssertion(Annotation(rdfs:label "EIF2AK4 (GCN2) dimer autophosphorylates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9633742")
-AnnotationAssertion(Annotation(rdfs:label "LINC01139 promotes phosphorylation of HIF1A by LRRK2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9634702")
-AnnotationAssertion(Annotation(rdfs:label "ALPK1 phosphorylates TIFA") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9645535")
-AnnotationAssertion(Annotation(rdfs:label "NEK6 and NEK7 phosphorylate EML4") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9648089")
-AnnotationAssertion(Annotation(rdfs:label "p-T-EIF2AK1:ferriheme dimer autophosphorylates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9648883")
-AnnotationAssertion(Annotation(rdfs:label "p-T,T486,T488-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9648888")
-AnnotationAssertion(Annotation(rdfs:label "MAP2K mutants constitutively phosphorylate MAPKs") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9652165")
-AnnotationAssertion(Annotation(rdfs:label "KRAS4B is phosphorylated on serine 181") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9653503")
-AnnotationAssertion(Annotation(rdfs:label "MAP2Ks phosphorylate MAPKs downstream of RAF1 mutants") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9656214")
-AnnotationAssertion(Annotation(rdfs:label "RAF1 mutant complexes phosphorylate MAP2K dimer") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9656215")
-AnnotationAssertion(Annotation(rdfs:label "PLK2, MAPK14 phosphorylate ADAM17") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9662823")
-AnnotationAssertion(Annotation(rdfs:label "Unknown kinase phosphorylates p-DVL") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9673346")
-AnnotationAssertion(Annotation(rdfs:label "GSK3 phosphorylates Nucleoprotein") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9683664")
-AnnotationAssertion(Annotation(rdfs:label "AKT phosphorylates FOXO3 downstream of FLT3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9699579")
-AnnotationAssertion(Annotation(rdfs:label "TBK1, IKBKE are autophosphorylated at Ser172") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9705320")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of TBK1/IKBKE") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9705323")
-AnnotationAssertion(Annotation(rdfs:label "MAPK1 phsophorylates ZC3HCF1 in a NPM-ALK-dependent manner") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9725030")
-AnnotationAssertion(Annotation(rdfs:label "GSK3 phosphorylates nucleoprotein") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9729260")
-AnnotationAssertion(Annotation(rdfs:label "Unknown kinase phosphorylates nucleoprotein") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9729300")
-AnnotationAssertion(Annotation(rdfs:label "CSNK1A1 phosphorylates nucleoprotein") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9729318")
-AnnotationAssertion(Annotation(rdfs:label "MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9731111")
-AnnotationAssertion(Annotation(rdfs:label "Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-975125")
-AnnotationAssertion(Annotation(rdfs:label "Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-975134")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-975160")
-AnnotationAssertion(Annotation(rdfs:label "IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-975170")
-AnnotationAssertion(Annotation(rdfs:label "First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-975180")
-AnnotationAssertion(Annotation(rdfs:label "Unknown kinase phosphorylates 9b") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9758486")
-AnnotationAssertion(Annotation(rdfs:label "Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-975853")
-AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomerl:activated TLR5 or 10 complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-975861")
-AnnotationAssertion(Annotation(rdfs:label "IRAK4 autophosphorylation within the complex activated TLR:MyD88") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-975865")
-AnnotationAssertion(Annotation(rdfs:label "Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-975874")
-AnnotationAssertion(Annotation(rdfs:label "First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-975878")
-AnnotationAssertion(Annotation(rdfs:label "GSK3B phosphorylates p-NFE2L2") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9762094")
-AnnotationAssertion(Annotation(rdfs:label "SQSTM1 oligomer is phosphorylated") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9766532")
-AnnotationAssertion(Annotation(rdfs:label "MAPK1,(MAPK3) phosphorylates NPAS4") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9769115")
-AnnotationAssertion(Annotation(rdfs:label "Active IKBKB phosphorylates NF-kappa-B inhibitor") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9773803")
-AnnotationAssertion(Annotation(rdfs:label "MAPKAPK2 phosphorylates RIPK1 at S320") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9815501")
-AnnotationAssertion(Annotation(rdfs:label "TBK1, IKBKE phosphorylate RIPK1 at T189") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9817397")
-AnnotationAssertion(Annotation(rdfs:label "CHUK, IKBKB phosphorylate RIPK1 at S25") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9818789")
-AnnotationAssertion(Annotation(rdfs:label "ULK1 phosphorylates RIPK1 at S357") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0004674> "Reactome:R-HSA-9819106")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "EC:2.7.11.1") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0004674> "protein serine kinase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0004674> "protein threonine kinase activity")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "EC:2.7.11.1") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0004674> "protein-serine kinase activity")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "EC:2.7.11.1") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0004674> "serine kinase activity")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "EC:2.7.11.1") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0004674> "serine protein kinase activity")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "EC:2.7.11.1") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0004674> "serine-specific protein kinase activity")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "EC:2.7.11.1") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0004674> "threonine-specific protein kinase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0004674> "molecular_function")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "EC:2.7.11.1") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0004674> "protein serine-threonine kinase activity")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "EC:2.7.11.1") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0004674> "serine(threonine) protein kinase activity")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "EC:2.7.11.1") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0004674> "serine/threonine protein kinase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0004674> "GO:0004674")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0004674> "protein serine/threonine kinase activity")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0004674> <http://purl.obolibrary.org/obo/GO_0004672>)
-
 # Class: <http://purl.obolibrary.org/obo/GO_0004713> (protein tyrosine kinase activity)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "RHEA:10596") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0004713> "Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.")
@@ -30409,18 +29673,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0005775> "vacu
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0005775> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0031974> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0005773>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0005775> <http://purl.obolibrary.org/obo/GO_0070013>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0005776> (autophagosome)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0198547684") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:11099404") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0005776> "A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0005776> "NIF_Subcellular:sao8663416959")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "NIF_Subcellular:sao8663416959") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0005776> "autophagic vacuole")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0005776> "cellular_component")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "NIF_Subcellular:sao8663416959") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0005776> "initial autophagic vacuole")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0005776> "GO:0005776")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0005776> "autophagosome")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0005776> <http://purl.obolibrary.org/obo/GO_0005773>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0005776> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002216> <http://purl.obolibrary.org/obo/GO_0016236>))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0005794> (Golgi apparatus)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0198506732") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0005794> "A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.")
@@ -32167,25 +31419,6 @@ SubClassOf(<http://purl.obolibrary.org/obo/GO_0006909> ObjectComplementOf(Object
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0006909> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002162> ObjectComplementOf(<http://purl.obolibrary.org/obo/NCBITaxon_4751>)))
 DisjointClasses(<http://purl.obolibrary.org/obo/GO_0006909> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002162> <http://purl.obolibrary.org/obo/NCBITaxon_4751>))
 
-# Class: <http://purl.obolibrary.org/obo/GO_0006914> (autophagy)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0198547684") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:11099404") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:9412464") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0006914> "The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_0006914> "GO:0016238")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0006914> "Wikipedia:Autophagy_(cellular)")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0006914> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0006914> "GO:0006914")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0006914> <http://purl.obolibrary.org/obo/go#goslim_chembl>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0006914> <http://purl.obolibrary.org/obo/go#goslim_drosophila>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0006914> <http://purl.obolibrary.org/obo/go#goslim_generic>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0006914> <http://purl.obolibrary.org/obo/go#goslim_pir>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0006914> <http://purl.obolibrary.org/obo/go#goslim_pombe>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0006914> "autophagy")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0006914> <http://purl.obolibrary.org/obo/GO_0044248>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0006914> <http://purl.obolibrary.org/obo/GO_0061919>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0006914> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002160> <http://purl.obolibrary.org/obo/NCBITaxon_2759>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0006914> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002230> <http://purl.obolibrary.org/obo/GO_0055085>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0006914> ObjectAllValuesFrom(<http://purl.obolibrary.org/obo/RO_0002162> <http://purl.obolibrary.org/obo/NCBITaxon_2759>))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0006915> (apoptotic process)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:cjm") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dhl") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:ecd") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:go_curators") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mtg_apoptosis") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:tb") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0198506732") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:18846107") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:21494263") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0006915> "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.")
@@ -34327,24 +33560,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <htt
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0008092> "cytoskeletal protein binding")
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0008092> <http://purl.obolibrary.org/obo/GO_0005515>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0008094> (ATP-dependent activity, acting on DNA)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:pdt") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0008094> "Catalytic activity that acts to modify DNA, driven by ATP hydrolysis.")
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0008094> "https://github.com/geneontology/go-ontology/issues/20876"^^xsd:anyURI)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0008094> "https://github.com/geneontology/go-ontology/issues/21612"^^xsd:anyURI)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0008094> "https://github.com/geneontology/go-ontology/issues/21775"^^xsd:anyURI)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_0008094> "GO:0004011")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0008094> "ATPase activity, acting on DNA")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0008094> "ATPase, acting on DNA")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0008094> "DNA dependent ATPase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0008094> "DNA-dependent ATPase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0008094> "DNA-dependent adenosinetriphosphatase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0008094> "adenosinetriphosphatase (DNA-dependent)")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0008094> "molecular_function")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0008094> "GO:0008094")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0008094> "ATP-dependent activity, acting on DNA")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0008094> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0140097> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/GO_0016887>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0008104> (protein localization)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:ai") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0008104> "Any process in which a protein is transported to, or maintained in, a specific location.")
@@ -34438,23 +33653,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0008152> "meta
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0008152> <http://purl.obolibrary.org/obo/GO_0008150>)
 DisjointClasses(<http://purl.obolibrary.org/obo/GO_0008152> <http://purl.obolibrary.org/obo/GO_0051179>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0008186> (ATP-dependent activity, acting on RNA)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:jl") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0008186> "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction.")
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0008186> "https://github.com/geneontology/go-ontology/issues/20876"^^xsd:anyURI)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0008186> "https://github.com/geneontology/go-ontology/issues/21775"^^xsd:anyURI)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_0008186> "GO:0004010")
-AnnotationAssertion(Annotation(rdfs:label "Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0008186> "Reactome:R-HSA-9770847")
-AnnotationAssertion(Annotation(rdfs:label "Disassembly of the Intron Lariat Spliceosome (new)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0008186> "Reactome:R-HSA-9772351")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0008186> "ATPase activity, acting on RNA")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0008186> "ATPase, acting on RNA")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0008186> "RNA-dependent ATPase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0008186> "RNA-dependent adenosinetriphosphatase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0008186> "molecular_function")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0008186> "GO:0008186")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0008186> "ATP-dependent activity, acting on RNA")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0008186> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0140657> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002233> <http://purl.obolibrary.org/obo/CHEBI_33697>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0008188> (neuropeptide receptor activity)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:ai") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0008188> "Combining with a neuropeptide to initiate a change in cell activity.")
@@ -34567,11 +33765,13 @@ SubClassOf(<http://purl.obolibrary.org/obo/GO_0008217> ObjectSomeValuesFrom(<htt
 # Class: <http://purl.obolibrary.org/obo/GO_0008219> (cell death)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mtg_apoptosis") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:25236395") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0008219> "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).")
+AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0008219> "https://github.com/geneontology/go-ontology/issues/24680"^^xsd:anyURI)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0008219> "biological_process")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0008219> "accidental cell death")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0008219> "necrosis")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0008219> "GO:0008219")
-AnnotationAssertion(rdfs:comment <http://purl.obolibrary.org/obo/GO_0008219> "This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term.")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0008219> <http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate>)
+AnnotationAssertion(rdfs:comment <http://purl.obolibrary.org/obo/GO_0008219> "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO.  When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms.")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0008219> "cell death")
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0008219> <http://purl.obolibrary.org/obo/GO_0009987>)
 
@@ -34993,20 +34193,6 @@ EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0008610> ObjectIntersection
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0008610> <http://purl.obolibrary.org/obo/GO_0009058>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0008610> <http://purl.obolibrary.org/obo/GO_1901576>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0008641> (ubiquitin-like modifier activating enzyme activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:jl") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0008641> "Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond.")
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0008641> "https://github.com/geneontology/go-ontology/issues/14208"^^xsd:anyURI)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_0008641> "GO:0008642")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0008641> "small protein activating enzyme activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0008641> "molecular_function")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0008641> "GO:0008641")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0008641> <http://purl.obolibrary.org/obo/go#goslim_pir>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0008641> "ubiquitin-like modifier activating enzyme activity")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0008641> <http://purl.obolibrary.org/obo/GO_0016877>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0008641> <http://purl.obolibrary.org/obo/GO_0140096>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0008641> <http://purl.obolibrary.org/obo/GO_0140657>)
-
 # Class: <http://purl.obolibrary.org/obo/GO_0008643> (carbohydrate transport)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:ai") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0008643> "The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y.")
@@ -35119,7 +34305,8 @@ SubClassOf(<http://purl.obolibrary.org/obo/GO_0009058> <http://purl.obolibrary.o
 # Class: <http://purl.obolibrary.org/obo/GO_0009059> (macromolecule biosynthetic process)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0009059> "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.")
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0009059> "http://amigo.geneontology.org/amigo/term/GO:0070589"^^xsd:anyURI)
+AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0009059> "https://github.com/geneontology/go-ontology/issues/15249"^^xsd:anyURI)
+AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0009059> "https://github.com/geneontology/go-ontology/issues/25418"^^xsd:anyURI)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_0009059> "GO:0043284")
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mtg_chebi_dec09") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009059> "biopolymer biosynthetic process")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009059> "macromolecule anabolism")
@@ -35132,6 +34319,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <htt
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0009059> "macromolecule biosynthetic process")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0009059> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0009058> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0004008> <http://purl.obolibrary.org/obo/CHEBI_33694>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0009059> <http://purl.obolibrary.org/obo/GO_0043170>)
+SubClassOf(<http://purl.obolibrary.org/obo/GO_0009059> <http://purl.obolibrary.org/obo/GO_0044249>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0009059> <http://purl.obolibrary.org/obo/GO_1901576>)
 
 # Class: <http://purl.obolibrary.org/obo/GO_0009063> (amino acid catabolic process)
@@ -35239,70 +34427,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0009101> "glyc
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0009101> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0009058> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0004008> <http://purl.obolibrary.org/obo/CHEBI_17089>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0009101> <http://purl.obolibrary.org/obo/GO_0009059>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0009132> (nucleoside diphosphate metabolic process)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:go_curators") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0198506732") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0009132> "The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009132> "nucleoside diphosphate metabolism")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0009132> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0009132> "GO:0009132")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0009132> "nucleoside diphosphate metabolic process")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0009132> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0008152> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0004007> <http://purl.obolibrary.org/obo/CHEBI_57930>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0009133> (nucleoside diphosphate biosynthetic process)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:go_curators") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0198506732") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0009133> "The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009133> "nucleoside diphosphate anabolism")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009133> "nucleoside diphosphate biosynthesis")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009133> "nucleoside diphosphate formation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009133> "nucleoside diphosphate synthesis")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0009133> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0009133> "GO:0009133")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0009133> "nucleoside diphosphate biosynthetic process")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0009133> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0009058> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0004008> <http://purl.obolibrary.org/obo/CHEBI_57930>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0009134> (nucleoside diphosphate catabolic process)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:go_curators") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0198506732") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0009134> "The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009134> "nucleoside diphosphate breakdown")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009134> "nucleoside diphosphate catabolism")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009134> "nucleoside diphosphate degradation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0009134> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0009134> "GO:0009134")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0009134> "nucleoside diphosphate catabolic process")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0009134> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0009056> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0004009> <http://purl.obolibrary.org/obo/CHEBI_57930>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0009141> (nucleoside triphosphate metabolic process)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:go_curators") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0198506732") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0009141> "The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009141> "nucleoside triphosphate metabolism")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0009141> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0009141> "GO:0009141")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0009141> "nucleoside triphosphate metabolic process")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0009141> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0008152> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0004007> <http://purl.obolibrary.org/obo/CHEBI_61557>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0009142> (nucleoside triphosphate biosynthetic process)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:go_curators") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0198506732") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0009142> "The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009142> "nucleoside triphosphate anabolism")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009142> "nucleoside triphosphate biosynthesis")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009142> "nucleoside triphosphate formation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009142> "nucleoside triphosphate synthesis")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0009142> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0009142> "GO:0009142")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0009142> "nucleoside triphosphate biosynthetic process")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0009142> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0009058> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0004008> <http://purl.obolibrary.org/obo/CHEBI_61557>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0009143> (nucleoside triphosphate catabolic process)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:go_curators") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0198506732") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0009143> "The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009143> "nucleoside triphosphate breakdown")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009143> "nucleoside triphosphate catabolism")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0009143> "nucleoside triphosphate degradation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0009143> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0009143> "GO:0009143")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0009143> "nucleoside triphosphate catabolic process")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0009143> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0009056> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0004009> <http://purl.obolibrary.org/obo/CHEBI_61557>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0009250> (glucan biosynthetic process)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:go_curators") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0009250> "The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.")
@@ -36419,14 +35543,15 @@ SubClassOf(<http://purl.obolibrary.org/obo/GO_0010464> <http://purl.obolibrary.o
 
 # Class: <http://purl.obolibrary.org/obo/GO_0010467> (gene expression)
 
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:txnOH-2018") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:25934543") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:31580950") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0010467> "The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, translation and maturation for protein-coding genes.")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:txnOH-2018") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:25934543") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:31580950") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0010467> "The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes.")
 AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0010467> "https://github.com/geneontology/go-ontology/issues/22557"^^xsd:anyURI)
+AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0010467> "https://github.com/geneontology/go-ontology/issues/25419"^^xsd:anyURI)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0010467> "Wikipedia:Gene_expression")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0010467> "biological_process")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0010467> "GO:0010467")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0010467> <http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon>)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0010467> "gene expression")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0010467> <http://purl.obolibrary.org/obo/GO_0043170>)
+SubClassOf(<http://purl.obolibrary.org/obo/GO_0010467> <http://purl.obolibrary.org/obo/GO_0009059>)
 
 # Class: <http://purl.obolibrary.org/obo/GO_0010468> (regulation of gene expression)
 
@@ -36498,30 +35623,6 @@ EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0010496> ObjectIntersection
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0010496> <http://purl.obolibrary.org/obo/GO_0006810>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0010496> <http://purl.obolibrary.org/obo/GO_0009987>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0010506> (regulation of autophagy)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:tb") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0010506> "Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0010506> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0010506> "GO:0010506")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0010506> "regulation of autophagy")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0010506> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_0006914>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0010507> (negative regulation of autophagy)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:tb") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0010507> "Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0010507> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0010507> "GO:0010507")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0010507> "negative regulation of autophagy")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0010507> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002212> <http://purl.obolibrary.org/obo/GO_0006914>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0010508> (positive regulation of autophagy)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:tb") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0010508> "Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0010508> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0010508> "GO:0010508")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0010508> "positive regulation of autophagy")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0010508> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0006914>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0010543> (regulation of platelet activation)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:BHF") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:tb") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0010543> "Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.")
@@ -37274,30 +36375,24 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0010764> "negative regulation of fibroblast migration")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0010764> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002212> <http://purl.obolibrary.org/obo/GO_0010761>)))
 
-# Class: <http://purl.obolibrary.org/obo/GO_0010769> (regulation of cell morphogenesis involved in differentiation)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:tb") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0010769> "Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0010769> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0010769> "GO:0010769")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0010769> "regulation of cell morphogenesis involved in differentiation")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0010769> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_0000904>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0010770> (positive regulation of cell morphogenesis involved in differentiation)
+# Class: <http://purl.obolibrary.org/obo/GO_0010770> (positive regulation of cell morphogenesis)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:tb") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0010770> "Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.")
+AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0010770> "https://github.com/geneontology/go-ontology/issues/24299"^^xsd:anyURI)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0010770> "biological_process")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0010770> "GO:0010770")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0010770> "positive regulation of cell morphogenesis involved in differentiation")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0010770> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0000904>)))
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0010770> "positive regulation of cell morphogenesis")
+EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0010770> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0000902>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0010770> <http://purl.obolibrary.org/obo/GO_0010720>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0010771> (negative regulation of cell morphogenesis involved in differentiation)
+# Class: <http://purl.obolibrary.org/obo/GO_0010771> (negative regulation of cell morphogenesis)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:tb") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0010771> "Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.")
+AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0010771> "https://github.com/geneontology/go-ontology/issues/24299"^^xsd:anyURI)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0010771> "biological_process")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0010771> "GO:0010771")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0010771> "negative regulation of cell morphogenesis involved in differentiation")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0010771> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002212> <http://purl.obolibrary.org/obo/GO_0000904>)))
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0010771> "negative regulation of cell morphogenesis")
+EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0010771> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002212> <http://purl.obolibrary.org/obo/GO_0000902>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0010771> <http://purl.obolibrary.org/obo/GO_0010721>)
 
 # Class: <http://purl.obolibrary.org/obo/GO_0010816> (calcitonin catabolic process)
@@ -39720,54 +38815,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0016202> "regu
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0016202> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_0014706>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0016202> <http://purl.obolibrary.org/obo/GO_0048634>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0016236> (macroautophagy)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:11099404") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:12914914") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:15798367") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:16973210") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:20159618") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:9412464") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0016236> "The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_0016236> "GO:0034262")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/GO_0016236> "autophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0016236> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0016236> "GO:0016236")
-AnnotationAssertion(rdfs:comment <http://purl.obolibrary.org/obo/GO_0016236> "Targeted macroautophagy sometimes targets regions of cytoplasm containing non-self, such as virus particles or components (e.g. see PMID:20159618). As this is essentially the same process as macroautophagy that encloses and digests only self, the term autophagy is still used despite the enclosure of some non-self (non-auto) entities.")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0016236> "macroautophagy")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0016236> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0006914> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002224> <http://purl.obolibrary.org/obo/GO_0000045>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0016236> <http://purl.obolibrary.org/obo/GO_0006914>)
-
-# Class: <http://purl.obolibrary.org/obo/GO_0016239> (positive regulation of macroautophagy)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:go_curators") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:9412464") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0016239> "Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:ascb_2009") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:tb") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016239> "positive regulation of starvation-induced autophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016239> "up regulation of macroautophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016239> "up-regulation of macroautophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016239> "upregulation of macroautophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0016239> "activation of macroautophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0016239> "stimulation of macroautophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0016239> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0016239> "GO:0016239")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0016239> "positive regulation of macroautophagy")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0016239> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0016236>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0016241> (regulation of macroautophagy)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:krc") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0016241> "Any process that modulates the frequency, rate or extent of macroautophagy.")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:ascb_2009") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:tb") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016241> "regulation of starvation-induced autophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0016241> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0016241> "GO:0016241")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0016241> "regulation of macroautophagy")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0016241> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_0016236>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0016242> (negative regulation of macroautophagy)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:go_curators") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0016242> "Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016242> "down regulation of macroautophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016242> "down-regulation of macroautophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016242> "downregulation of macroautophagy")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:ascb_2009") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:tb") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016242> "negative regulation of starvation-induced autophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0016242> "inhibition of macroautophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0016242> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0016242> "GO:0016242")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0016242> "negative regulation of macroautophagy")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0016242> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002212> <http://purl.obolibrary.org/obo/GO_0016236>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0016301> (kinase activity)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0198506732") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0016301> "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.")
@@ -39884,15 +38931,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0016447> "soma
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0016447> <http://purl.obolibrary.org/obo/GO_0002562>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0016447> <http://purl.obolibrary.org/obo/GO_0016445>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0016462> (pyrophosphatase activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:curators") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "https://en.wikipedia.org/wiki/Pyrophosphatase") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0016462> "Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups.")
-AnnotationAssertion(Annotation(rdfs:label "NUDT13 hydrolyses AP6A to AP4 and ADP") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016462> "Reactome:R-HSA-6810472")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0016462> "molecular_function")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0016462> "GO:0016462")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0016462> "pyrophosphatase activity")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0016462> <http://purl.obolibrary.org/obo/GO_0016818>)
-
 # Class: <http://purl.obolibrary.org/obo/GO_0016477> (cell migration)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:cjm") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:ems") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:pf") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Wikipedia:Cell_migration") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0016477> "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues.")
@@ -40021,35 +39059,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <htt
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0016740> "transferase activity")
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0016740> <http://purl.obolibrary.org/obo/GO_0003824>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0016746> (acyltransferase activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:jl") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0198506732") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0016746> "Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).")
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0016746> "https://github.com/geneontology/go-ontology/issues/20486"^^xsd:anyURI)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_0016746> "GO:0008415")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016746> "EC:2.3.-.-")
-AnnotationAssertion(Annotation(rdfs:label "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016746> "Reactome:R-HSA-159431")
-AnnotationAssertion(Annotation(rdfs:label "Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016746> "Reactome:R-HSA-192312")
-AnnotationAssertion(Annotation(rdfs:label "Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016746> "Reactome:R-HSA-193491")
-AnnotationAssertion(Annotation(rdfs:label "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016746> "Reactome:R-HSA-6792572")
-AnnotationAssertion(Annotation(rdfs:label "HRASLS transfer acyl group from PC to PE to form NAPE") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016746> "Reactome:R-HSA-8858298")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016746> "transferase activity, transferring acyl groups")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0016746> "molecular_function")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0016746> "GO:0016746")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0016746> <http://purl.obolibrary.org/obo/go#goslim_chembl>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0016746> <http://purl.obolibrary.org/obo/go#goslim_drosophila>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0016746> "acyltransferase activity")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0016746> <http://purl.obolibrary.org/obo/GO_0016740>)
-
-# Class: <http://purl.obolibrary.org/obo/GO_0016755> (aminoacyltransferase activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:jl") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0016755> "Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor).")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016755> "EC:2.3.2.-")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016755> "transferase activity, transferring amino-acyl groups")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0016755> "molecular_function")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0016755> "GO:0016755")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0016755> "aminoacyltransferase activity")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0016755> <http://purl.obolibrary.org/obo/GO_0016746>)
-
 # Class: <http://purl.obolibrary.org/obo/GO_0016772> (transferase activity, transferring phosphorus-containing groups)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:jl") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0198506732") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0016772> "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).")
@@ -40114,106 +39123,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <htt
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0016788> "hydrolase activity, acting on ester bonds")
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0016788> <http://purl.obolibrary.org/obo/GO_0016787>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0016817> (hydrolase activity, acting on acid anhydrides)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:jl") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0016817> "Catalysis of the hydrolysis of any acid anhydride.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016817> "EC:3.6.-.-")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0016817> "hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0016817> "molecular_function")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0016817> "GO:0016817")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0016817> "hydrolase activity, acting on acid anhydrides")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0016817> <http://purl.obolibrary.org/obo/GO_0016787>)
-
-# Class: <http://purl.obolibrary.org/obo/GO_0016818> (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:jl") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0016818> "Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016818> "EC:3.6.1.-")
-AnnotationAssertion(Annotation(rdfs:label "NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016818> "Reactome:R-HSA-9731590")
-AnnotationAssertion(Annotation(rdfs:label "NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016818> "Reactome:R-HSA-9731613")
-AnnotationAssertion(Annotation(rdfs:label "NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016818> "Reactome:R-HSA-9731632")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0016818> "molecular_function")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0016818> "GO:0016818")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0016818> "hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0016818> <http://purl.obolibrary.org/obo/GO_0016817>)
-
-# Class: <http://purl.obolibrary.org/obo/GO_0016874> (ligase activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0016874> "Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient.")
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0016874> "https://github.com/geneontology/go-ontology/issues/19380"^^xsd:anyURI)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016874> "EC:6.-.-.-")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:jh2") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016874> "synthetase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0016874> "molecular_function")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0016874> "GO:0016874")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0016874> <http://purl.obolibrary.org/obo/go#goslim_candida>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0016874> <http://purl.obolibrary.org/obo/go#goslim_chembl>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0016874> <http://purl.obolibrary.org/obo/go#goslim_drosophila>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0016874> <http://purl.obolibrary.org/obo/go#goslim_generic>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0016874> <http://purl.obolibrary.org/obo/go#goslim_metagenomics>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0016874> <http://purl.obolibrary.org/obo/go#goslim_mouse>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0016874> <http://purl.obolibrary.org/obo/go#goslim_pir>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0016874> <http://purl.obolibrary.org/obo/go#goslim_yeast>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0016874> <http://purl.obolibrary.org/obo/go#prokaryote_subset>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0016874> "ligase activity")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0016874> <http://purl.obolibrary.org/obo/GO_0003824>)
-
-# Class: <http://purl.obolibrary.org/obo/GO_0016877> (ligase activity, forming carbon-sulfur bonds)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "EC:6.2.-.-") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0016877> "Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016877> "EC:6.2.-.-")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016877> "ligase activity, forming carbon-sulphur bonds")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0016877> "molecular_function")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0016877> "GO:0016877")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0016877> "ligase activity, forming carbon-sulfur bonds")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0016877> <http://purl.obolibrary.org/obo/GO_0016874>)
-
-# Class: <http://purl.obolibrary.org/obo/GO_0016887> (ATP hydrolysis activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "RHEA:13065") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0016887> "Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.")
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0016887> "https://github.com/geneontology/go-ontology/issues/19078"^^xsd:anyURI)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0016887> "https://github.com/geneontology/go-ontology/issues/20498"^^xsd:anyURI)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0016887> "https://github.com/geneontology/go-ontology/issues/21612"^^xsd:anyURI)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0016887> "https://github.com/geneontology/go-ontology/issues/22371"^^xsd:anyURI)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_0016887> "GO:0004002")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_0016887> "GO:0042623")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "RHEA:13065")
-AnnotationAssertion(Annotation(rdfs:label "NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B)") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-159101")
-AnnotationAssertion(Annotation(rdfs:label "ATP hydrolysis by HSP70") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-3371422")
-AnnotationAssertion(Annotation(rdfs:label "Trafficking of GluR2-containing AMPA receptors to synapse") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-416985")
-AnnotationAssertion(Annotation(rdfs:label "ATP hydrolysis by HSP90") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-5618093")
-AnnotationAssertion(Annotation(rdfs:label "SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-5654989")
-AnnotationAssertion(Annotation(rdfs:label "NSF ATPase activity dissociates cis-SNARE") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-5694425")
-AnnotationAssertion(Annotation(rdfs:label "NSF ATPase activity dissociates cis-SNARE at cis-Golgi") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-6809015")
-AnnotationAssertion(Annotation(rdfs:label "NSF ATPase activity dissociates cis-SNARE at the ER") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-6811422")
-AnnotationAssertion(Annotation(rdfs:label "ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-6814670")
-AnnotationAssertion(Annotation(rdfs:label "ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-6814678")
-AnnotationAssertion(Annotation(rdfs:label "NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-6814683")
-AnnotationAssertion(Annotation(rdfs:label "ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-8847638")
-AnnotationAssertion(Annotation(rdfs:label "HSPA8-mediated ATP hydrolysis promotes vesicle uncoating") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-8868658")
-AnnotationAssertion(Annotation(rdfs:label "HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-8939203")
-AnnotationAssertion(Annotation(rdfs:label "Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-9038161")
-AnnotationAssertion(Annotation(rdfs:label "ESCRT Disassembly") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-917693")
-AnnotationAssertion(Annotation(rdfs:label "Tail-anchored protein:SGTA:BAG6:GET4:UBL4A:ASNA1:ATP dissociates and ASNA1 hydrolyzes ATP yielding Tail-anchored protein:ASNA1:ADP") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-9609860")
-AnnotationAssertion(Annotation(rdfs:label "VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-9668415")
-AnnotationAssertion(Annotation(rdfs:label "RHOBTB3 hydrolyzes ATP") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-9706399")
-AnnotationAssertion(Annotation(rdfs:label "ATP-dependent release of CDT1 from the OCCM complex") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0016887> "Reactome:R-HSA-9749350")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016887> "ATP hydrolase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016887> "ATP phosphohydrolase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016887> "adenosine 5'-triphosphatase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016887> "adenosine triphosphatase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0016887> "adenosinetriphosphatase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0016887> "molecular_function")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0016887> "ATP monophosphatase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0016887> "GO:0016887")
-AnnotationAssertion(rdfs:comment <http://purl.obolibrary.org/obo/GO_0016887> "Note that this term is meant to specifically represent the ATPase activity of proteins using ATP as a source of energy to drive a reaction. If possible, gene products should also be annotated to a child of 'ATP-dependent activity ; GO:0140657', to capture their overall function.")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0016887> "ATP hydrolysis activity")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0016887> <http://purl.obolibrary.org/obo/GO_0017111>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0016887> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0140657>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0016887> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000057> <http://purl.obolibrary.org/obo/CHEBI_15377>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0016887> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000057> <http://purl.obolibrary.org/obo/CHEBI_15378>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0016887> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000057> <http://purl.obolibrary.org/obo/CHEBI_30616>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0016887> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000057> <http://purl.obolibrary.org/obo/CHEBI_43474>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0016887> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000057> <http://purl.obolibrary.org/obo/CHEBI_456216>))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0016907> (G protein-coupled acetylcholine receptor activity)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bf") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:fj") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0016907> "Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.")
@@ -40258,41 +39167,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0017046> "pept
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0017046> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0005488> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002233> <http://purl.obolibrary.org/obo/CHEBI_25905>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0017046> <http://purl.obolibrary.org/obo/GO_0042562>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0017111> (ribonucleoside triphosphate phosphatase activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "RHEA:23680") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0017111> "Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate.")
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0017111> "https://github.com/geneontology/go-ontology/issues/21232"^^xsd:anyURI)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0017111> "https://github.com/geneontology/go-ontology/issues/23401"^^xsd:anyURI)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/GO_0017111> "apyrase activity")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "EC:3.6.1.15") <http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/GO_0017111> "nucleoside 5-triphosphatase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/GO_0017111> "nucleoside triphosphatase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/GO_0017111> "nucleoside triphosphate hydrolase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/GO_0017111> "nucleoside triphosphate phosphatase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/GO_0017111> "nucleoside-triphosphatase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0017111> "EC:3.6.1.15")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0017111> "MetaCyc:NUCLEOSIDE-TRIPHOSPHATASE-RXN")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0017111> "RHEA:23680")
-AnnotationAssertion(Annotation(rdfs:label "NTPDase1 hydrolyzes nucleoside triphosphates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0017111> "Reactome:R-HSA-8850846")
-AnnotationAssertion(Annotation(rdfs:label "NTPDase2 hydrolyzes nucleoside triphosphates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0017111> "Reactome:R-HSA-8851089")
-AnnotationAssertion(Annotation(rdfs:label "NTPDase3 hydrolyzes nucleoside triphosphates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0017111> "Reactome:R-HSA-8851110")
-AnnotationAssertion(Annotation(rdfs:label "NTPDase4 hydrolyzes nucleoside triphosphates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0017111> "Reactome:R-HSA-8851234")
-AnnotationAssertion(Annotation(rdfs:label "NTPDase7 hydrolyzes nucleoside triphosphates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0017111> "Reactome:R-HSA-8851494")
-AnnotationAssertion(Annotation(rdfs:label "NTPDase8 hydrolyzes nucleoside triphosphates") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0017111> "Reactome:R-HSA-8851538")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0017111> "NTPase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0017111> "molecular_function")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0017111> "nucleoside triphosphate phosphohydrolase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0017111> "nucleoside-5-triphosphate phosphohydrolase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0017111> "GO:0017111")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0017111> <http://purl.obolibrary.org/obo/go#goslim_chembl>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0017111> <http://purl.obolibrary.org/obo/go#goslim_metagenomics>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0017111> "ribonucleoside triphosphate phosphatase activity")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0017111> <http://purl.obolibrary.org/obo/GO_0016462>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0017111> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000057> <http://purl.obolibrary.org/obo/CHEBI_15377>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0017111> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000057> <http://purl.obolibrary.org/obo/CHEBI_15378>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0017111> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000057> <http://purl.obolibrary.org/obo/CHEBI_43474>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0017111> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000057> <http://purl.obolibrary.org/obo/CHEBI_57930>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0017111> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000057> <http://purl.obolibrary.org/obo/CHEBI_61557>))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0017126> (nucleologenesis)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:jl") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0198506732") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0017126> "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells.")
@@ -40768,67 +39642,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0019752> "carb
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0019752> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0008152> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0004007> <http://purl.obolibrary.org/obo/CHEBI_29067>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0019752> <http://purl.obolibrary.org/obo/GO_0043436>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0019777> (Atg12 transferase activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:12826404") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0019777> "Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y = Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages.")
-AnnotationAssertion(Annotation(rdfs:label "ATG10 transfers ATG12 from ATG7 to ATG10") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0019777> "Reactome:R-HSA-5681999")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0019777> "APG12 conjugating enzyme activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0019777> "APG12 ligase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0019777> "Atg12 conjugating enzyme activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0019777> "Atg12 ligase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0019777> "molecular_function")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0019777> "GO:0019777")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0019777> "Atg12 transferase activity")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0019777> <http://purl.obolibrary.org/obo/GO_0019787>)
-
-# Class: <http://purl.obolibrary.org/obo/GO_0019778> (Atg12 activating enzyme activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0019778> "Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0019778> "molecular_function")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:vw") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0019778> "APG12 activating enzyme activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0019778> "GO:0019778")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0019778> "Atg12 activating enzyme activity")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0019778> <http://purl.obolibrary.org/obo/GO_0008641>)
-
-# Class: <http://purl.obolibrary.org/obo/GO_0019786> (protein-phosphatidylethanolamide deconjugating activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:22240591") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:22652539") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:28330855") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:2882172") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:28901328") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0019786> "Catalysis of the reaction: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine. An example of this reaction is the removal of ATG8 from membranes to which it is covalently linked to a phosphatidylethanolamid via its terminal glycine residue.")
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0019786> "https://github.com/geneontology/go-ontology/issues/25472"^^xsd:anyURI)
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "skos:narrowMatch") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0019786> "Atg8-specific protease activity")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:vw") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0019786> "APG8-specific protease activity")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "skos:narrowMatch") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0019786> "ATG8-PE deconjugation activity")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "skos:narrowMatch") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0019786> "ATG8-PE hydrolase activity")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "skos:narrowMatch") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0019786> "Atg8-specific peptidase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0019786> "molecular_function")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "skos:narrowMatch") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0019786> "APG8-PE hydrolase")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0019786> "GO:0019786")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0019786> "protein-phosphatidylethanolamide deconjugating activity")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0019786> <http://purl.obolibrary.org/obo/GO_0016787>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0019786> <http://purl.obolibrary.org/obo/GO_0140096>)
-
-# Class: <http://purl.obolibrary.org/obo/GO_0019787> (ubiquitin-like protein transferase activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:rn") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:10806345") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:10884686") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0019787> "Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y = Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein.")
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0019787> "https://github.com/geneontology/go-ontology/issues/24697"^^xsd:anyURI)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_0019787> "GO:0008639")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_0019787> "GO:0008640")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/GO_0019787> "E2")
-AnnotationAssertion(Annotation(rdfs:label "ATG16L1 complex transfers LC3 from ATG3 to PE") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0019787> "Reactome:R-HSA-5678490")
-AnnotationAssertion(Annotation(rdfs:label "RIP2 is K63 polyubiquitinated") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0019787> "Reactome:R-HSA-688137")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0019787> "small conjugating protein transferase activity")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0019787> "small conjugating protein ligase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0019787> "small protein conjugating enzyme activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0019787> "ubiquitin-like conjugating enzyme activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0019787> "ubiquitin-like-protein ligase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0019787> "molecular_function")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0019787> "E3")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0019787> "GO:0019787")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0019787> <http://purl.obolibrary.org/obo/go#goslim_drosophila>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0019787> <http://purl.obolibrary.org/obo/go#goslim_pir>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0019787> "ubiquitin-like protein transferase activity")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0019787> <http://purl.obolibrary.org/obo/GO_0016755>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0019787> <http://purl.obolibrary.org/obo/GO_0140096>)
-
 # Class: <http://purl.obolibrary.org/obo/GO_0019814> (immunoglobulin complex)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:add") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:jl") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0781765196") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0019814> "A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.")
@@ -43819,7 +42632,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0030030> <http://purl.obolibrary.org/obo/go#prokaryote_subset>)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0030030> "cell projection organization")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0030030> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0016043> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002592> <http://purl.obolibrary.org/obo/GO_0042995>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0030030> <http://purl.obolibrary.org/obo/GO_0009987>)
+SubClassOf(<http://purl.obolibrary.org/obo/GO_0030030> <http://purl.obolibrary.org/obo/GO_0008283>)
 
 # Class: <http://purl.obolibrary.org/obo/GO_0030031> (cell projection assembly)
 
@@ -44814,20 +43627,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0030397> "memb
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0030397> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0022411> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002590> <http://purl.obolibrary.org/obo/GO_0016020>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0030397> <http://purl.obolibrary.org/obo/GO_0061024>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0030399> (autophagosome membrane disassembly)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0030399> "The controlled breakdown of the membranes of autophagosomes.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0030399> "autophagic membrane breakdown")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0030399> "autophagic vacuole membrane disassembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0030399> "autophagic membrane catabolism")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0030399> "autophagic membrane degradation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0030399> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0030399> "GO:0030399")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0030399> "autophagosome membrane disassembly")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0030399> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0022411> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002590> <http://purl.obolibrary.org/obo/GO_0000421>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0030399> <http://purl.obolibrary.org/obo/GO_0030397>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0030399> <http://purl.obolibrary.org/obo/GO_1905037>)
-
 # Class: <http://purl.obolibrary.org/obo/GO_0030421> (defecation)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0030421> "The expulsion of feces from the rectum.")
@@ -49091,40 +47890,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0032774> <http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate>)
 AnnotationAssertion(rdfs:comment <http://purl.obolibrary.org/obo/GO_0032774> "Note that, in some cases, viral RNA replication and viral transcription from RNA actually refer to the same process, but may be called differently depending on the focus of a specific research study.")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0032774> "RNA biosynthetic process")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0032774> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0009058> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0004008> <http://purl.obolibrary.org/obo/CHEBI_33697>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0032780> (negative regulation of ATP-dependent activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0032780> "Any process that stops or reduces the rate of an ATP-dependent activity.")
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0032780> "https://github.com/geneontology/go-ontology/issues/22371"^^xsd:anyURI)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0032780> "down regulation of ATPase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0032780> "down-regulation of ATPase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0032780> "downregulation of ATPase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0032780> "negative regulation of ATPase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0032780> "negative regulation of adenosinetriphosphatase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0032780> "inhibition of ATPase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0032780> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0032780> "GO:0032780")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0032780> <http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0032780> "negative regulation of ATP-dependent activity")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0032780> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002212> <http://purl.obolibrary.org/obo/GO_0140657>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0032781> (positive regulation of ATP-dependent activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0032781> "Any process that activates or increases the rate of an ATP-dependent activity.")
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0032781> "https://github.com/geneontology/go-ontology/issues/22371"^^xsd:anyURI)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0032781> "positive regulation of ATPase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0032781> "positive regulation of adenosinetriphosphatase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0032781> "up regulation of ATPase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0032781> "up-regulation of ATPase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0032781> "upregulation of ATPase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0032781> "activation of ATPase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0032781> "stimulation of ATPase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0032781> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0032781> "GO:0032781")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0032781> <http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0032781> "positive regulation of ATP-dependent activity")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0032781> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0140657>)))
+EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0032774> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0009059> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0004008> <http://purl.obolibrary.org/obo/CHEBI_33697>)))
 
 # Class: <http://purl.obolibrary.org/obo/GO_0032782> (bile acid secretion)
 
@@ -51892,35 +50658,6 @@ EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0035051> ObjectIntersection
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0035051> <http://purl.obolibrary.org/obo/GO_0030154>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0035051> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0007507>))
 
-# Class: <http://purl.obolibrary.org/obo/GO_0035070> (salivary gland histolysis)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bf") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mtg_apoptosis") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:9409683") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0035070> "The stage-specific break down of the larval salivary glands during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0035070> "salivary gland regression")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0035070> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0035070> "GO:0035070")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0035070> "salivary gland histolysis")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0035070> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0060033> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002298> <http://purl.obolibrary.org/obo/UBERON_0001044>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0035070> <http://purl.obolibrary.org/obo/GO_0007435>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0035070> <http://purl.obolibrary.org/obo/GO_0009886>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0035070> <http://purl.obolibrary.org/obo/GO_0060033>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0035070> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0007552>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0035070> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0048707>))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0035071> (salivary gland cell autophagic cell death)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bf") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mtg_apoptosis") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:10882130") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0035071> "The stage-specific programmed cell death of salivary gland cells during salivary gland histolysis.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0035071> "autophagic cell death of salivary gland cells")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0035071> "programmed cell death of salivary gland cells by autophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0035071> "salivary gland cell death")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0035071> "salivary gland cell programmed cell death by autophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0035071> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0035071> "GO:0035071")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0035071> "salivary gland cell autophagic cell death")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0035071> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0008219> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002299> <http://purl.obolibrary.org/obo/UBERON_0001044>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0035071> <http://purl.obolibrary.org/obo/GO_0010623>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0035071> <http://purl.obolibrary.org/obo/GO_0048102>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0035071> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0035070>))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0035082> (axoneme assembly)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bf") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:cilia") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:jl") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0815316194") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0035082> "The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.")
@@ -53908,7 +52645,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date>
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0036344> "biological_process")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0036344> "GO:0036344")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0036344> "platelet morphogenesis")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0036344> <http://purl.obolibrary.org/obo/GO_0000904>)
+SubClassOf(<http://purl.obolibrary.org/obo/GO_0036344> <http://purl.obolibrary.org/obo/GO_0000902>)
 
 # Class: <http://purl.obolibrary.org/obo/GO_0036345> (platelet maturation)
 
@@ -54856,7 +53593,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0042133> "GO:0042133")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0042133> <http://purl.obolibrary.org/obo/go#goslim_pir>)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0042133> "neurotransmitter metabolic process")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0042133> <http://purl.obolibrary.org/obo/GO_0001505>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0042133> <http://purl.obolibrary.org/obo/GO_0044237>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0042133> ObjectComplementOf(ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002162> <http://purl.obolibrary.org/obo/NCBITaxon_4895>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0042133> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002162> ObjectComplementOf(<http://purl.obolibrary.org/obo/NCBITaxon_4895>)))
@@ -58065,18 +56801,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0043455> "regulation of secondary metabolic process")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0043455> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_0019748>)))
 
-# Class: <http://purl.obolibrary.org/obo/GO_0043462> (regulation of ATP-dependent activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:jl") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0043462> "Any process that modulates the rate of an ATP-dependent activity.")
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0043462> "https://github.com/geneontology/go-ontology/issues/22371"^^xsd:anyURI)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0043462> "regulation of ATPase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0043462> "regulation of adenosinetriphosphatase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0043462> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0043462> "GO:0043462")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0043462> <http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0043462> "regulation of ATP-dependent activity")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0043462> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_0140657>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0043467> (regulation of generation of precursor metabolites and energy)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:jl") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0043467> "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances.")
@@ -58883,17 +57607,17 @@ DisjointClasses(<http://purl.obolibrary.org/obo/GO_0044297> ObjectSomeValuesFrom
 
 # Class: <http://purl.obolibrary.org/obo/GO_0044302> (dentate gyrus mossy fiber)
 
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "NIF_Subcellular:nlx_subcell_20090601") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:17765709") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0044302> "Distinctive, unmyelinated axons produced by granule cells.")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "NIF_Subcellular:nlx_subcell_20090601") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:17765709") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0044302> "Distinctive, unmyelinated axons produced by dentate gyrus granule cells.")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0044302> "jl")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0044302> "2010-02-05T11:23:55Z")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/GO_0044302> "granule cell axon")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/GO_0044302> "NIF_Subcellular:nlx_subcell_20090601")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0044302> "dentate gyrus mossy fibre")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0044302> "granule cell axon")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0044302> "cellular_component")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0044302> "GO:0044302")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0044302> "dentate gyrus mossy fiber")
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0044302> <http://purl.obolibrary.org/obo/GO_0030424>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0044302> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/CL_0000120>))
+SubClassOf(<http://purl.obolibrary.org/obo/GO_0044302> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/CL_2000089>))
 
 # Class: <http://purl.obolibrary.org/obo/GO_0044306> (neuron projection terminus)
 
@@ -59054,19 +57778,6 @@ SubClassOf(<http://purl.obolibrary.org/obo/GO_0044782> <http://purl.obolibrary.o
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0044782> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002160> <http://purl.obolibrary.org/obo/NCBITaxon_2759>))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0044782> ObjectAllValuesFrom(<http://purl.obolibrary.org/obo/RO_0002162> <http://purl.obolibrary.org/obo/NCBITaxon_2759>))
 
-# Class: <http://purl.obolibrary.org/obo/GO_0044804> (nucleophagy)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:jl") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:24013549") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0044804> "A form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucleus is degraded.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0044804> "jl")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0044804> "2013-09-10T15:50:25Z")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0044804> "autophagy of nucleus")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0044804> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0044804> "nucleus degradation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0044804> "GO:0044804")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0044804> "nucleophagy")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0044804> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0006914> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002233> <http://purl.obolibrary.org/obo/GO_0005634>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0044804> <http://purl.obolibrary.org/obo/GO_0006914>)
-
 # Class: <http://purl.obolibrary.org/obo/GO_0044872> (lipoprotein localization)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:jl") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0044872> "Any process in which a lipoprotein is transported to, or maintained in, a specific location.")
@@ -64035,23 +62746,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0048087> "positive regulation of developmental pigmentation")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0048087> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0048066>)))
 
-# Class: <http://purl.obolibrary.org/obo/GO_0048102> (autophagic cell death)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mtg_apoptosis") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:18846107") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:23347517") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0048102> "A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/GO_0048102> "autophagic death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:pr") <http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/GO_0048102> "programmed cell death by autophagy")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:cjm") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0048102> "programmed cell death by macroautophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0048102> "biological_process")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:25236395") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0048102> "autosis")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:sl") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0048102> "type II programmed cell death")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0048102> "GO:0048102")
-AnnotationAssertion(rdfs:comment <http://purl.obolibrary.org/obo/GO_0048102> "The precise nature of autophagic cell death is still being debated, and the link between autophagy and cell death unclear. As autophagy is often induced under conditions of stress that could also lead to cell death, there has been a propagation of the idea that autophagy can act as a cell death mechanism; but others suggest that autophagy may simply be an attempt of dying cells to adapt to lethal stress rather than a mechanism to execute a cell death program. Further studies are required to resolve this controversy (see e.g. PMID:22082964, PMID:22052193, PMID:25236395). In the meantime, curators should carefully examine the experimental evidence presented in papers concerning autophagic cell death, and annotate accordingly. Recently, an instance of autophagic cell death, termed autosis, was discovered that relies on the plasma membrane Na+/K+-ATPase. Autosis was observed in vivo in the brain of rats subjected to an ischemic insult. It's still unclear if all cases of autophagic cell death require the Na+/K+-ATPase or not.")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0048102> "autophagic cell death")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0048102> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0012501> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/GO_0016236>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0048102> <http://purl.obolibrary.org/obo/GO_0012501>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0048102> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002160> <http://purl.obolibrary.org/obo/NCBITaxon_2759>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0048102> ObjectAllValuesFrom(<http://purl.obolibrary.org/obo/RO_0002162> <http://purl.obolibrary.org/obo/NCBITaxon_2759>))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0048103> (somatic stem cell division)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:jid") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0582227089") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0048103> "The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.")
@@ -65174,7 +63868,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0048601> "GO:0048601")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0048601> "oocyte morphogenesis")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0048601> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0009653> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002298> <http://purl.obolibrary.org/obo/CL_0000023>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0048601> <http://purl.obolibrary.org/obo/GO_0000904>)
+SubClassOf(<http://purl.obolibrary.org/obo/GO_0048601> <http://purl.obolibrary.org/obo/GO_0000902>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0048601> <http://purl.obolibrary.org/obo/GO_0003006>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0048601> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0048599>))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0048601> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002160> <http://purl.obolibrary.org/obo/NCBITaxon_33208>))
@@ -66784,7 +65478,7 @@ AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#has
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0048938> "biological_process")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0048938> "GO:0048938")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0048938> "lateral line nerve glial cell morphogenesis involved in differentiation")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0048938> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0000904> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0048937>)))
+EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0048938> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0000902> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0048937>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0048938> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002298> <http://purl.obolibrary.org/obo/CL_1000050>))
 
 # Class: <http://purl.obolibrary.org/obo/GO_0048939> (anterior lateral line nerve glial cell development)
@@ -66803,7 +65497,7 @@ AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#has
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0048940> "biological_process")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0048940> "GO:0048940")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0048940> "anterior lateral line nerve glial cell morphogenesis involved in differentiation")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0048940> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0000904> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0048939>)))
+EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0048940> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0000902> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0048939>)))
 
 # Class: <http://purl.obolibrary.org/obo/GO_0048941> (posterior lateral line nerve glial cell development)
 
@@ -66821,7 +65515,7 @@ AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#has
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0048942> "biological_process")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0048942> "GO:0048942")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0048942> "posterior lateral line nerve glial cell morphogenesis involved in differentiation")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0048942> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0000904> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0048941>)))
+EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0048942> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0000902> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0048941>)))
 
 # Class: <http://purl.obolibrary.org/obo/GO_0050000> (chromosome localization)
 
@@ -67355,7 +66049,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0050775> "positive regulation of dendrite morphogenesis")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0050775> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0048813>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0050775> <http://purl.obolibrary.org/obo/GO_0050769>)
-SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#http://purl.obolibrary.org/obo/IAO_0000233> "https://github.com/geneontology/go-ontology/issues/13926") <http://purl.obolibrary.org/obo/GO_0050775> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0000904>))
+SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#http://purl.obolibrary.org/obo/IAO_0000233> "https://github.com/geneontology/go-ontology/issues/13926") <http://purl.obolibrary.org/obo/GO_0050775> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0000902>))
 
 # Class: <http://purl.obolibrary.org/obo/GO_0050776> (regulation of immune response)
 
@@ -69752,16 +68446,6 @@ AnnotationAssertion(rdfs:comment <http://purl.obolibrary.org/obo/GO_0051338> "Th
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0051338> "regulation of transferase activity")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0051338> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_0016740>)))
 
-# Class: <http://purl.obolibrary.org/obo/GO_0051340> (regulation of ligase activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:ai") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0051340> "Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0051340> "ligase regulator")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0051340> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0051340> "GO:0051340")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0051340> <http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0051340> "regulation of ligase activity")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0051340> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_0016874>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0051345> (positive regulation of hydrolase activity)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:ai") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0051345> "Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.")
@@ -69824,35 +68508,6 @@ AnnotationAssertion(rdfs:comment <http://purl.obolibrary.org/obo/GO_0051348> "Th
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0051348> "negative regulation of transferase activity")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0051348> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002212> <http://purl.obolibrary.org/obo/GO_0016740>)))
 
-# Class: <http://purl.obolibrary.org/obo/GO_0051351> (positive regulation of ligase activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:ai") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0051351> "Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0051351> "ligase activator")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0051351> "up regulation of ligase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0051351> "up-regulation of ligase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0051351> "upregulation of ligase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0051351> "activation of ligase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0051351> "stimulation of ligase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0051351> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0051351> "GO:0051351")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0051351> <http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0051351> "positive regulation of ligase activity")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0051351> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0016874>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0051352> (negative regulation of ligase activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:ai") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0051352> "Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0051352> "down regulation of ligase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0051352> "down-regulation of ligase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0051352> "downregulation of ligase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0051352> "ligase inhibitor")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_0051352> "inhibition of ligase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0051352> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0051352> "GO:0051352")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0051352> <http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0051352> "negative regulation of ligase activity")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0051352> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002212> <http://purl.obolibrary.org/obo/GO_0016874>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0051355> (proprioception involved in equilibrioception)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:ai") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0051355> "The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity.")
@@ -69949,7 +68604,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0051402> "neuron apoptotic process")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0051402> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0006915> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000066> <http://purl.obolibrary.org/obo/CL_0000540>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0051402> <http://purl.obolibrary.org/obo/GO_0006915>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0051402> <http://purl.obolibrary.org/obo/GO_0070997>)
 
 # Class: <http://purl.obolibrary.org/obo/GO_0051410> (detoxification of nitrogen compound)
 
@@ -71856,29 +70510,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0060021> "roof
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0060021> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0048856> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002296> <http://purl.obolibrary.org/obo/UBERON_0007375>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0060021> <http://purl.obolibrary.org/obo/GO_0048856>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0060032> (notochord regression)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0060032> "The developmental process in which the stucture of the notochord is destroyed in an embryo.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0060032> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0060032> "GO:0060032")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0060032> "notochord regression")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0060032> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0060033> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002233> <http://purl.obolibrary.org/obo/UBERON_0002328>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0060032> <http://purl.obolibrary.org/obo/GO_0060033>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0060032> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0048570>))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0060033> (anatomical structure regression)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0060033> "The developmental process in which an anatomical stucture is destroyed as a part of its normal progression.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0060033> "biological_process")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mtg_apoptosis") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0060033> "histolysis")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mtg_apoptosis") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0060033> "tissue death")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0060033> "GO:0060033")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0060033> "anatomical structure regression")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0060033> <http://purl.obolibrary.org/obo/GO_0032502>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0060033> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0009653>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0060033> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002160> <http://purl.obolibrary.org/obo/NCBITaxon_2759>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0060033> ObjectAllValuesFrom(<http://purl.obolibrary.org/obo/RO_0002162> <http://purl.obolibrary.org/obo/NCBITaxon_2759>))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0060034> (notochord cell differentiation)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0060034> "The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate.")
@@ -74423,18 +73054,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0060632> "regulation of microtubule-based movement")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0060632> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_0007018>)))
 
-# Class: <http://purl.obolibrary.org/obo/GO_0060641> (mammary gland duct regression in males)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:12558599") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0060641> "The process in which the epithelium of the mammary duct is destroyed in males.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0060641> "dph")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0060641> "2009-05-20T04:50:57Z")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0060641> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0060641> "GO:0060641")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0060641> "mammary gland duct regression in males")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0060641> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0060033> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002233> <http://purl.obolibrary.org/obo/UBERON_0001765>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0060641> <http://purl.obolibrary.org/obo/GO_0060033>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0060641> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0060603>))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0060642> (white fat cell differentiation involved in mammary gland fat development)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:12558599") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0060642> "The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.")
@@ -77904,7 +76523,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date>
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0061336> "biological_process")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0061336> "GO:0061336")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0061336> "cell morphogenesis involved in Malpighian tubule morphogenesis")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0061336> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0000904> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0007443>)))
+EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0061336> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0000902> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0007443>)))
 
 # Class: <http://purl.obolibrary.org/obo/GO_0061337> (cardiac conduction)
 
@@ -78760,55 +77379,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0061629> "RNA polymerase II-specific DNA-binding transcription factor binding")
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0061629> <http://purl.obolibrary.org/obo/GO_0140297>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0061650> (ubiquitin-like protein conjugating enzyme activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0061650> "Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another via the reaction X-SCP + Y = Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0061650> "dph")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0061650> "2014-11-06T13:15:27Z")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/GO_0061650> "E2")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0061650> "small conjugating protein conjugating enzyme activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0061650> "molecular_function")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0061650> "GO:0061650")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0061650> "ubiquitin-like protein conjugating enzyme activity")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0061650> <http://purl.obolibrary.org/obo/GO_0019787>)
-
-# Class: <http://purl.obolibrary.org/obo/GO_0061651> (Atg12 conjugating enzyme activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0061651> "Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y = Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0061651> "dph")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0061651> "2014-11-06T13:17:36Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") <http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/GO_0061651> "E2")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0061651> "molecular_function")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0061651> "GO:0061651")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0061651> "Atg12 conjugating enzyme activity")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0061651> <http://purl.obolibrary.org/obo/GO_0019777>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0061651> <http://purl.obolibrary.org/obo/GO_0061650>)
-
-# Class: <http://purl.obolibrary.org/obo/GO_0061659> (ubiquitin-like protein ligase activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0061659> "Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S = X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0061659> "dph")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0061659> "2014-11-06T13:46:23Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0061659> "small conjugating protein ligase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0061659> "molecular_function")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0061659> "E3")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0061659> "GO:0061659")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0061659> "ubiquitin-like protein ligase activity")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0061659> <http://purl.obolibrary.org/obo/GO_0019787>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0061659> <http://purl.obolibrary.org/obo/GO_0140096>)
-
-# Class: <http://purl.obolibrary.org/obo/GO_0061660> (Atg12 ligase activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0061660> "Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S = X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0061660> "dph")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0061660> "2014-11-06T13:50:42Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") <http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/GO_0061660> "E3")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0061660> "molecular_function")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0061660> "GO:0061660")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0061660> "Atg12 ligase activity")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0061660> <http://purl.obolibrary.org/obo/GO_0019777>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0061660> <http://purl.obolibrary.org/obo/GO_0061659>)
-
 # Class: <http://purl.obolibrary.org/obo/GO_0061682> (seminal vesicle morphogenesis)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0061682> "The process in which the anatomical structures of a seminal vesicle are generated and organized.")
@@ -78860,17 +77430,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0061695> "tran
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0061695> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0032991> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002215> <http://purl.obolibrary.org/obo/GO_0016772>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0061695> <http://purl.obolibrary.org/obo/GO_1990234>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0061736> (engulfment of target by autophagosome)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:PARL") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:pad") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0061736> "The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0061736> "dph")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0061736> "2015-09-14T14:10:24Z")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0061736> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0061736> "GO:0061736")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0061736> "engulfment of target by autophagosome")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0061736> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0010324> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0000045>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0061736> <http://purl.obolibrary.org/obo/GO_0010324>)
-
 # Class: <http://purl.obolibrary.org/obo/GO_0061792> (secretory granule maturation)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:PARL") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bf") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:16618809") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0061792> "Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling.")
@@ -79036,27 +77595,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0061900> "glia
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0061900> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0001775> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002233> <http://purl.obolibrary.org/obo/CL_0000125>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0061900> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0150076>))
 
-# Class: <http://purl.obolibrary.org/obo/GO_0061906> (autophagosome localization)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:26763909") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0061906> "Any process in which an autophagosome is transported to, and/or maintained in, a specific location within the cell.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0061906> "dph")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0061906> "2017-06-28T17:27:57Z")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0061906> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0061906> "GO:0061906")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0061906> "autophagosome localization")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0061906> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0051179> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0004009> <http://purl.obolibrary.org/obo/GO_0005776>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0061919> (process utilizing autophagic mechanism)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:21997368") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:22966490") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:28596378") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0061919> "A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0061919> "dph")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0061919> "2017-07-13T19:42:14Z")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0061919> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0061919> "GO:0061919")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0061919> <http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0061919> "process utilizing autophagic mechanism")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0061919> <http://purl.obolibrary.org/obo/GO_0009987>)
-
 # Class: <http://purl.obolibrary.org/obo/GO_0061938> (protein localization to somatodendritic compartment)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:18341993") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0061938> "A process in which a protein is transported to or maintained in a location within the somatodendritic compartment.")
@@ -80648,20 +79186,6 @@ EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0070977> ObjectIntersection
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0070977> <http://purl.obolibrary.org/obo/GO_0071695>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0070977> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0060348>))
 
-# Class: <http://purl.obolibrary.org/obo/GO_0070997> (neuron death)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:BHF") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0070997> "The process of cell death in a neuron.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0070997> "mah")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0070997> "2009-11-03T02:37:17Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:rl") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0070997> "neuron cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0070997> "neuronal cell death")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0070997> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0070997> "GO:0070997")
-AnnotationAssertion(rdfs:comment <http://purl.obolibrary.org/obo/GO_0070997> "This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide or use of neuron-specific markers) show that neuron death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the neuron death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'), and the cell type captured as an annotation extension; or the term GO:0051402 'neuron apoptotic process' may be considered, if appropriate.")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0070997> "neuron death")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0070997> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0008219> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000066> <http://purl.obolibrary.org/obo/CL_0000540>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0070997> <http://purl.obolibrary.org/obo/GO_0008219>)
-
 # Class: <http://purl.obolibrary.org/obo/GO_0070998> (sensory perception of gravity)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0070998> "The series of events required for an organism to receive a gravitational stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.")
@@ -81245,7 +79769,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date>
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0071695> "biological_process")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0071695> "GO:0071695")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0071695> "anatomical structure maturation")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0071695> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0021700> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002299> <http://purl.obolibrary.org/obo/CARO_0000003>)))
+EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0071695> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0021700> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002299> <http://purl.obolibrary.org/obo/UBERON_0000061>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0071695> <http://purl.obolibrary.org/obo/GO_0021700>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0071695> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0048856>))
 
@@ -81829,39 +80353,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0071897> "DNA biosynthetic process")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0071897> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0009058> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0004008> <http://purl.obolibrary.org/obo/CHEBI_16991>)))
 
-# Class: <http://purl.obolibrary.org/obo/GO_0071900> (regulation of protein serine/threonine kinase activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0071900> "Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0071900> "mah")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0071900> "2010-09-15T03:08:35Z")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0071900> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0071900> "GO:0071900")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0071900> <http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0071900> "regulation of protein serine/threonine kinase activity")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0071900> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_0004674>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0071901> (negative regulation of protein serine/threonine kinase activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:BHF") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0071901> "Any process that decreases the rate, frequency, or extent of protein serine/threonine kinase activity.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0071901> "mah")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0071901> "2010-09-15T03:09:43Z")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0071901> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0071901> "GO:0071901")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0071901> <http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0071901> "negative regulation of protein serine/threonine kinase activity")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0071901> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002212> <http://purl.obolibrary.org/obo/GO_0004674>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_0071902> (positive regulation of protein serine/threonine kinase activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0071902> "Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0071902> "mah")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0071902> "2010-09-15T03:09:57Z")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0071902> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0071902> "GO:0071902")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0071902> <http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0071902> "positive regulation of protein serine/threonine kinase activity")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0071902> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0004674>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0071941> (nitrogen cycle metabolic process)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mah") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:16675690") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Wikipedia:Nitrogen_cycle") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0071941> "A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization.")
@@ -85613,7 +84104,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0090171> "GO:0090171")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0090171> "chondrocyte morphogenesis")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0090171> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0009653> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002299> <http://purl.obolibrary.org/obo/CL_0000138>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_0090171> <http://purl.obolibrary.org/obo/GO_0000904>)
+SubClassOf(<http://purl.obolibrary.org/obo/GO_0090171> <http://purl.obolibrary.org/obo/GO_0000902>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0090171> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0002063>))
 
 # Class: <http://purl.obolibrary.org/obo/GO_0090174> (organelle membrane fusion)
@@ -88269,16 +86760,17 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0099156> "cell-cell signaling via exosome")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0099156> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0007267> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002608> <http://purl.obolibrary.org/obo/GO_0070062>)))
 
-# Class: <http://purl.obolibrary.org/obo/GO_0099157> (trans-synaptic signalling via exosome)
+# Class: <http://purl.obolibrary.org/obo/GO_0099157> (trans-synaptic signaling via exosome)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dos") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:19837038") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0099157> "Transynaptic signaling in which the ligand is carried across the synapse by an exosome.")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0099157> "dos")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0099157> "2017-07-05T16:49:44Z")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0099157> "exosome mediated transynaptic signalling")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0099157> "trans-synaptic signalling via exosome")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0099157> "biological_process")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0099157> "GO:0099157")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0099157> <http://purl.obolibrary.org/obo/go#goslim_synapse>)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0099157> "trans-synaptic signalling via exosome")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0099157> "trans-synaptic signaling via exosome")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0099157> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0099537> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002608> <http://purl.obolibrary.org/obo/GO_0070062>)))
 
 # Class: <http://purl.obolibrary.org/obo/GO_0099160> (postsynaptic intermediate filament cytoskeleton)
@@ -88704,8 +87196,8 @@ SubClassOf(<http://purl.obolibrary.org/obo/GO_0099555> <http://purl.obolibrary.o
 # Class: <http://purl.obolibrary.org/obo/GO_0099565> (chemical synaptic transmission, postsynaptic)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dos") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0099565> "The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol.")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasSynonymType> <http://purl.obolibrary.org/obo/go#syngo_official_label>) <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0099565> "postsynaptic process involved in chemical synaptic transmission")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0099565> "biological_process")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasSynonymType> <http://purl.obolibrary.org/obo/go#syngo_official_label>) <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_0099565> "postsynaptic process involved in chemical synaptic transmission")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0099565> "GO:0099565")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0099565> <http://purl.obolibrary.org/obo/go#goslim_synapse>)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0099565> "chemical synaptic transmission, postsynaptic")
@@ -89470,6 +87962,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <htt
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0110165> "cellular anatomical entity")
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0110165> <http://purl.obolibrary.org/obo/CARO_0000000>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0110165> <http://purl.obolibrary.org/obo/GO_0005575>)
+SubClassOf(<http://purl.obolibrary.org/obo/GO_0110165> <http://purl.obolibrary.org/obo/UBERON_0000061>)
 
 # Class: <http://purl.obolibrary.org/obo/GO_0120006> (regulation of glutamatergic neuron differentiation)
 
@@ -90444,29 +88937,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0140650> "radi
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0140650> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0016477> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002565> <http://purl.obolibrary.org/obo/CL_0000598>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0140650> <http://purl.obolibrary.org/obo/GO_0001764>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_0140657> (ATP-dependent activity)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:24878343") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:25750732") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:32933017") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:33818025") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:33873056") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:33988324") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0140657> "A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient.")
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0140657> "https://github.com/geneontology/go-ontology/issues/21612"^^xsd:anyURI)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000233> <http://purl.obolibrary.org/obo/GO_0140657> "https://github.com/geneontology/go-ontology/issues/22371"^^xsd:anyURI)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0140657> "pg")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0140657> "2021-06-15T07:35:06Z")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0140657> "ATP hydrolysis-dependent activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0140657> "ATPase activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0140657> "ATPase activity, coupled")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0140657> "ATPase-dependent activity")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0140657> "molecular_function")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0140657> "GO:0140657")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0140657> <http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0140657> <http://purl.obolibrary.org/obo/go#goslim_chembl>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0140657> <http://purl.obolibrary.org/obo/go#goslim_drosophila>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0140657> <http://purl.obolibrary.org/obo/go#goslim_generic>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0140657> <http://purl.obolibrary.org/obo/go#goslim_yeast>)
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/GO_0140657> <http://purl.obolibrary.org/obo/go#prokaryote_subset>)
-AnnotationAssertion(rdfs:comment <http://purl.obolibrary.org/obo/GO_0140657> "Note that this term represents a grouping class that includes all proteins that use ATP hydrolysis to drive a reaction; it is not meant to capture the ATP hydrolysis reaction itself. To annotate ATP hydrolysis, please use 'ATP hydrolysis activity ; GO:0016887'.")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0140657> "ATP-dependent activity")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0140657> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0003674> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/GO_0016887>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_0140667> (regulation of oxytocin production)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:25096581") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0140667> "Any process that modulates the frequency, rate, or extent of production of oxytocin.")
@@ -90664,7 +89134,7 @@ EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0150079> ObjectIntersection
 
 # Class: <http://purl.obolibrary.org/obo/GO_0150098> (glial cell-neuron signaling)
 
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:aruk") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bc") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:14980203") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:16144764") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:16547515") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:18685038") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:27788368") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:9459440") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0150098> "Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signalling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum.")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:aruk") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bc") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:14980203") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:16144764") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:16547515") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:18685038") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:27788368") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:9459440") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0150098> "Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signaling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum.")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0150098> "bc")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0150098> "2018-12-17T12:28:09Z")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0150098> "glia-neuron signaling")
@@ -90681,7 +89151,7 @@ EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0150098> ObjectIntersection
 
 # Class: <http://purl.obolibrary.org/obo/GO_0150099> (neuron-glial cell signaling)
 
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:aruk") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bc") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:10195197") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:10196584") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:10377338") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:10493741") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:11356870") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:11399439") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:15252819") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:27788368") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0150099> "Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signalling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine.")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:aruk") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bc") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:10195197") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:10196584") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:10377338") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:10493741") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:11356870") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:11399439") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:15252819") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:27788368") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0150099> "Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signaling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine.")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0150099> "bc")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0150099> "2018-12-17T12:30:12Z")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0150099> "neuron-glia signaling")
@@ -92661,68 +91131,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1901212> "posi
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1901212> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0003207>)))
 SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#http://purl.obolibrary.org/obo/IAO_0000233> "https://github.com/geneontology/go-ontology/issues/13926") <http://purl.obolibrary.org/obo/GO_1901212> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0003206>))
 
-# Class: <http://purl.obolibrary.org/obo/GO_1901214> (regulation of neuron death)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:rph") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1901214> "Any process that modulates the frequency, rate or extent of neuron death.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_1901214> "rph")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_1901214> "2012-08-02T09:57:41Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901214> "regulation of neuron cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901214> "regulation of neuronal cell death")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_1901214> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_1901214> "GO:1901214")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1901214> "regulation of neuron death")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1901214> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_0070997>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_1901214> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002160> <http://purl.obolibrary.org/obo/NCBITaxon_33208>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_1901214> ObjectAllValuesFrom(<http://purl.obolibrary.org/obo/RO_0002162> <http://purl.obolibrary.org/obo/NCBITaxon_33208>))
-
-# Class: <http://purl.obolibrary.org/obo/GO_1901215> (negative regulation of neuron death)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:rph") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1901215> "Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_1901215> "rph")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_1901215> "2012-08-02T09:58:07Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901215> "down regulation of neuron cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901215> "down regulation of neuron death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901215> "down regulation of neuronal cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901215> "down-regulation of neuron cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901215> "down-regulation of neuron death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901215> "down-regulation of neuronal cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901215> "downregulation of neuron cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901215> "downregulation of neuron death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901215> "downregulation of neuronal cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901215> "negative regulation of neuron cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901215> "negative regulation of neuronal cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1901215> "inhibition of neuron cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1901215> "inhibition of neuron death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1901215> "inhibition of neuronal cell death")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_1901215> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_1901215> "GO:1901215")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1901215> "negative regulation of neuron death")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1901215> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002212> <http://purl.obolibrary.org/obo/GO_0070997>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_1901216> (positive regulation of neuron death)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:rph") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1901216> "Any process that activates or increases the frequency, rate or extent of neuron death.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_1901216> "rph")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_1901216> "2012-08-02T09:58:15Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901216> "positive regulation of neuron cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901216> "positive regulation of neuronal cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901216> "up regulation of neuron cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901216> "up regulation of neuron death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901216> "up regulation of neuronal cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901216> "up-regulation of neuron cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901216> "up-regulation of neuron death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901216> "up-regulation of neuronal cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901216> "upregulation of neuron cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901216> "upregulation of neuron death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1901216> "upregulation of neuronal cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1901216> "activation of neuron cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1901216> "activation of neuron death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1901216> "activation of neuronal cell death")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_1901216> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_1901216> "GO:1901216")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1901216> "positive regulation of neuron death")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1901216> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0070997>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_1901219> (regulation of cardiac chamber morphogenesis)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:BHF") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1901219> "Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis.")
@@ -95642,19 +94050,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1902533> "positive regulation of intracellular signal transduction")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1902533> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0035556>)))
 
-# Class: <http://purl.obolibrary.org/obo/GO_1902554> (serine/threonine protein kinase complex)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bhm") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:18191223") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1902554> "A protein complex which is capable of protein serine/threonine kinase activity.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_1902554> "bhm")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_1902554> "2013-12-06T16:06:12Z")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_1902554> "cellular_component")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1902554> "PDR16 complex dimer")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1902554> "PDR16 complex homodimer")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_1902554> "GO:1902554")
-AnnotationAssertion(rdfs:comment <http://purl.obolibrary.org/obo/GO_1902554> "An example is IRE1 in S. cerevisiae (UniProt ID P32361) in PMID:18191223 (inferred from direct assay).")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1902554> "serine/threonine protein kinase complex")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1902554> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0032991> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002215> <http://purl.obolibrary.org/obo/GO_0004674>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_1902563> (regulation of neutrophil activation)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:17588661") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1902563> "Any process that modulates the frequency, rate or extent of neutrophil activation.")
@@ -96727,42 +95122,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1902877> "positive regulation of embryonic pattern specification")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1902877> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0009880>)))
 
-# Class: <http://purl.obolibrary.org/obo/GO_1902902> (negative regulation of autophagosome assembly)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:als") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO_REF:0000058") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:21975012") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1902902> "Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_1902902> "als")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_1902902> "2014-04-15T10:37:40Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "down regulation of autophagic vacuole assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "down regulation of autophagosome biosynthesis")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "down regulation of autophagosome formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "down-regulation of autophagic vacuole assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "down-regulation of autophagosome biosynthesis")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "down-regulation of autophagosome formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "downregulation of autophagic vacuole assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "downregulation of autophagosome biosynthesis")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "downregulation of autophagosome formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "negative regulation of autophagic vacuole assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "negative regulation of autophagosome biosynthesis")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "negative regulation of autophagosome formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "down regulation of PAS formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "down-regulation of PAS formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "downregulation of PAS formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "inhibition of PAS formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "inhibition of autophagic vacuole assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "inhibition of autophagosome biosynthesis")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "inhibition of autophagosome formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "negative regulation of PAS formation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_1902902> "biological_process")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "down regulation of autophagic vacuole formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "down-regulation of autophagic vacuole formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "downregulation of autophagic vacuole formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "inhibition of autophagic vacuole formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1902902> "negative regulation of autophagic vacuole formation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_1902902> "GO:1902902")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1902902> "negative regulation of autophagosome assembly")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1902902> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002212> <http://purl.obolibrary.org/obo/GO_0000045>)))
-SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#http://purl.obolibrary.org/obo/IAO_0000233> "https://github.com/geneontology/go-ontology/issues/13926") <http://purl.obolibrary.org/obo/GO_1902902> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002212> <http://purl.obolibrary.org/obo/GO_0016236>))
-
 # Class: <http://purl.obolibrary.org/obo/GO_1902903> (regulation of supramolecular fiber organization)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:PARL") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:rl") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO_REF:0000058") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:23921388") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1902903> "Any process that modulates the frequency, rate or extent of supramolecular fiber organization.")
@@ -100423,68 +98782,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1904075> "positive regulation of trophectodermal cell proliferation")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1904075> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0001834>)))
 
-# Class: <http://purl.obolibrary.org/obo/GO_1904092> (regulation of autophagic cell death)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bhm") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO_REF:0000058") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:25736836") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1904092> "Any process that modulates the frequency, rate or extent of autophagic cell death.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_1904092> "bhm")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_1904092> "2015-03-26T16:41:32Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/GO_1904092> "regulation of autophagic death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/GO_1904092> "regulation of programmed cell death by autophagy")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904092> "regulation of programmed cell death by macroautophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_1904092> "biological_process")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1904092> "regulation of type II programmed cell death")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_1904092> "GO:1904092")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1904092> "regulation of autophagic cell death")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1904092> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_0048102>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_1904093> (negative regulation of autophagic cell death)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bhm") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO_REF:0000058") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:25736836") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1904093> "Any process that stops, prevents or reduces the frequency, rate or extent of autophagic cell death.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_1904093> "bhm")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_1904093> "2015-03-26T16:41:39Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904093> "down regulation of autophagic cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904093> "down regulation of programmed cell death by macroautophagy")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904093> "down-regulation of autophagic cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904093> "down-regulation of programmed cell death by macroautophagy")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904093> "downregulation of autophagic cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904093> "downregulation of programmed cell death by macroautophagy")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904093> "negative regulation of programmed cell death by macroautophagy")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1904093> "inhibition of autophagic cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1904093> "inhibition of programmed cell death by macroautophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_1904093> "biological_process")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1904093> "down regulation of type II programmed cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1904093> "down-regulation of type II programmed cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1904093> "downregulation of type II programmed cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1904093> "inhibition of type II programmed cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1904093> "negative regulation of type II programmed cell death")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_1904093> "GO:1904093")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1904093> "negative regulation of autophagic cell death")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1904093> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002212> <http://purl.obolibrary.org/obo/GO_0048102>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_1904094> (positive regulation of autophagic cell death)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bhm") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO_REF:0000058") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:25736836") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1904094> "Any process that activates or increases the frequency, rate or extent of autophagic cell death.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_1904094> "bhm")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_1904094> "2015-03-26T16:41:45Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904094> "positive regulation of programmed cell death by macroautophagy")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904094> "up regulation of autophagic cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904094> "up regulation of programmed cell death by macroautophagy")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904094> "up-regulation of autophagic cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904094> "up-regulation of programmed cell death by macroautophagy")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904094> "upregulation of autophagic cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904094> "upregulation of programmed cell death by macroautophagy")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1904094> "activation of autophagic cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1904094> "activation of programmed cell death by macroautophagy")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_1904094> "biological_process")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1904094> "activation of type II programmed cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1904094> "positive regulation of type II programmed cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1904094> "up regulation of type II programmed cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1904094> "up-regulation of type II programmed cell death")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1904094> "upregulation of type II programmed cell death")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_1904094> "GO:1904094")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1904094> "positive regulation of autophagic cell death")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1904094> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0048102>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_1904106> (protein localization to microvillus)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:kmv") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO_REF:0000087") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:25335890") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1904106> "A process in which a protein is transported to, or maintained in, a location within a microvillus.")
@@ -102849,31 +101146,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1904738> "vascular associated smooth muscle cell migration")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1904738> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0016477> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002565> <http://purl.obolibrary.org/obo/CL_0000359>)))
 
-# Class: <http://purl.obolibrary.org/obo/GO_1904745> (Atg1/ULK1 kinase complex assembly)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:dph") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO_REF:0000079") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:25139988") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1904745> "The aggregation, arrangement and bonding together of a set of components to form an Atg1/UKL1 kinase complex.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_1904745> "dph")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_1904745> "2015-10-19T12:33:08Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904745> "ATG1 kinase complex assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904745> "ATG1 kinase complex formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904745> "ATG1-ATG13 complex assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904745> "ATG1-ATG13 complex formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904745> "ATG1/ULK1 kinase complex formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904745> "ATG1/ULK1 signaling complex assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904745> "ATG1/ULK1 signaling complex formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904745> "Atg1p signalling complex assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904745> "Atg1p signalling complex formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904745> "ULK1 signaling complex assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904745> "ULK1 signaling complex formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904745> "ULK1-ATG13-FIP200 complex assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904745> "ULK1-ATG13-FIP200 complex formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904745> "ULK1-ATG13-RB1CC1 complex assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1904745> "ULK1-ATG13-RB1CC1 complex formation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_1904745> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_1904745> "GO:1904745")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1904745> "Atg1/ULK1 kinase complex assembly")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1904745> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0022607> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002588> <http://purl.obolibrary.org/obo/GO_1990316>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_1904746> (negative regulation of apoptotic process involved in development)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO_REF:0000058") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:22801495") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1904746> "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development.")
@@ -103956,18 +102228,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1904948> "midb
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1904948> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0030154> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002315> <http://purl.obolibrary.org/obo/CL_2000097>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_1904948> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0030901>))
 
-# Class: <http://purl.obolibrary.org/obo/GO_1904949> (ATPase complex)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bhm") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO_REF:0000088") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:9606181") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1904949> "A protein complex which is capable of ATPase activity.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_1904949> "bhm")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_1904949> "2016-02-04T22:13:32Z")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1904949> "VPS4 complex")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_1904949> "cellular_component")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_1904949> "GO:1904949")
-AnnotationAssertion(rdfs:comment <http://purl.obolibrary.org/obo/GO_1904949> "An example of this is VPS4 in Saccharomyces cerevisiae (UniProt ID P52917) in PMID:9606181 (inferred from direct assay).")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1904949> "ATPase complex")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1904949> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0032991> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002215> <http://purl.obolibrary.org/obo/GO_0016887>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_1904950> (negative regulation of establishment of protein localization)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO_REF:0000058") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:22761445") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1904950> "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization.")
@@ -104173,19 +102433,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1904989> "positive regulation of endothelial cell activation")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1904989> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0042118>)))
 
-# Class: <http://purl.obolibrary.org/obo/GO_1905037> (autophagosome organization)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:PARL") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bf") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:22186024") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1905037> "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_1905037> "bf")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_1905037> "2016-03-08T14:18:10Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905037> "autophagic vacuole organization")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_1905037> "biological_process")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_1905037> "initial autophagic vacuole organization")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_1905037> "GO:1905037")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1905037> "autophagosome organization")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1905037> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0016043> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002592> <http://purl.obolibrary.org/obo/GO_0005776>)))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_1905037> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0016236>))
-
 # Class: <http://purl.obolibrary.org/obo/GO_1905039> (carboxylic acid transmembrane transport)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO_REF:0000069") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:10869563") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1905039> "The process in which carboxylic acid is transported across a membrane.")
@@ -104438,23 +102685,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1905111> "positive regulation of pulmonary blood vessel remodeling")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1905111> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0101010>)))
 
-# Class: <http://purl.obolibrary.org/obo/GO_1905114> (cell surface receptor signaling pathway involved in cell-cell signaling)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO_REF:0000060") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0-7167-3051-0") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1905114> "Any cell surface receptor signaling pathway that is involved in cell-cell signaling.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_1905114> "dos")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_1905114> "2016-04-06T16:59:57Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905114> "cell surface receptor linked signal transduction involved in cell-cell signaling")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905114> "cell surface receptor linked signal transduction involved in cell-cell signalling")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905114> "cell surface receptor linked signaling pathway involved in cell-cell signaling")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905114> "cell surface receptor linked signaling pathway involved in cell-cell signalling")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905114> "cell surface receptor linked signalling pathway involved in cell-cell signaling")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905114> "cell surface receptor linked signalling pathway involved in cell-cell signalling")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905114> "cell surface receptor signaling pathway involved in cell-cell signalling")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_1905114> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_1905114> "GO:1905114")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1905114> "cell surface receptor signaling pathway involved in cell-cell signaling")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1905114> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0007166> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0007267>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_1905126> (regulation of axo-dendritic protein transport)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO_REF:0000058") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:20694152") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1905126> "Any process that modulates the frequency, rate or extent of axo-dendritic protein transport.")
@@ -104981,7 +103211,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_1905219> "GO:1905219")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1905219> "regulation of platelet formation")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1905219> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_0030220>)))
-SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#http://purl.obolibrary.org/obo/IAO_0000233> "https://github.com/geneontology/go-ontology/issues/13926") <http://purl.obolibrary.org/obo/GO_1905219> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_0000904>))
+SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#http://purl.obolibrary.org/obo/IAO_0000233> "https://github.com/geneontology/go-ontology/issues/13926") <http://purl.obolibrary.org/obo/GO_1905219> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_0000902>))
 
 # Class: <http://purl.obolibrary.org/obo/GO_1905220> (negative regulation of platelet formation)
 
@@ -105020,7 +103250,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_1905221> "GO:1905221")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1905221> "positive regulation of platelet formation")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1905221> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0030220>)))
-SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#http://purl.obolibrary.org/obo/IAO_0000233> "https://github.com/geneontology/go-ontology/issues/13926") <http://purl.obolibrary.org/obo/GO_1905221> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0000904>))
+SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#http://purl.obolibrary.org/obo/IAO_0000233> "https://github.com/geneontology/go-ontology/issues/13926") <http://purl.obolibrary.org/obo/GO_1905221> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0000902>))
 
 # Class: <http://purl.obolibrary.org/obo/GO_1905223> (epicardium morphogenesis)
 
@@ -107422,209 +105652,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1905833> "nega
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1905833> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002212> <http://purl.obolibrary.org/obo/GO_0007020>)))
 SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#http://purl.obolibrary.org/obo/IAO_0000233> "https://github.com/geneontology/go-ontology/issues/13926") <http://purl.obolibrary.org/obo/GO_1905833> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002212> <http://purl.obolibrary.org/obo/GO_0046785>))
 
-# Class: <http://purl.obolibrary.org/obo/GO_1905864> (regulation of Atg1/ULK1 kinase complex assembly)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mf") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO_REF:0000058") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:26567215") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1905864> "Any process that modulates the frequency, rate or extent of Atg1/ULK1 kinase complex assembly.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_1905864> "pr")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_1905864> "2017-01-26T13:23:26Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905864> "regulation of ATG1 kinase complex assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905864> "regulation of ATG1 kinase complex formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905864> "regulation of ATG1-ATG13 complex assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905864> "regulation of ATG1-ATG13 complex formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905864> "regulation of ATG1/ULK1 kinase complex formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905864> "regulation of ATG1/ULK1 signaling complex assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905864> "regulation of ATG1/ULK1 signaling complex formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905864> "regulation of Atg1p signalling complex assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905864> "regulation of Atg1p signalling complex formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905864> "regulation of ULK1 signaling complex assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905864> "regulation of ULK1 signaling complex formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905864> "regulation of ULK1-ATG13-FIP200 complex assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905864> "regulation of ULK1-ATG13-FIP200 complex formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905864> "regulation of ULK1-ATG13-RB1CC1 complex assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905864> "regulation of ULK1-ATG13-RB1CC1 complex formation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_1905864> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_1905864> "GO:1905864")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1905864> "regulation of Atg1/ULK1 kinase complex assembly")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1905864> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_1904745>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_1905865> (negative regulation of Atg1/ULK1 kinase complex assembly)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mf") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO_REF:0000058") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:26567215") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1905865> "Any process that stops, prevents or reduces the frequency, rate or extent of Atg1/ULK1 kinase complex assembly.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_1905865> "pr")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_1905865> "2017-01-26T13:23:35Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1905865> "down regulation of ATG1 kinase complex assembly")
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-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1905866> "activation of ULK1-ATG13-FIP200 complex assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1905866> "activation of ULK1-ATG13-FIP200 complex formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1905866> "activation of ULK1-ATG13-RB1CC1 complex assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") <http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym> <http://purl.obolibrary.org/obo/GO_1905866> "activation of ULK1-ATG13-RB1CC1 complex formation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_1905866> "biological_process")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_1905866> "GO:1905866")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1905866> "positive regulation of Atg1/ULK1 kinase complex assembly")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1905866> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_1904745>)))
-
 # Class: <http://purl.obolibrary.org/obo/GO_1905867> (epididymis development)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:TermGenie") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO_REF:0000094") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:12388089") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1905867> "The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure.")
@@ -108283,31 +106310,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1990280> "RNA
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_1990280> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0006403> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002339> <http://purl.obolibrary.org/obo/GO_0000785>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_1990280> <http://purl.obolibrary.org/obo/GO_0006403>)
 
-# Class: <http://purl.obolibrary.org/obo/GO_1990316> (Atg1/ULK1 kinase complex)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:DOS") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bhm") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:rb") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:15743910") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:19211835") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:19258318") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:19597335") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:22885598") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1990316> "A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_1990316> "bhm")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_1990316> "2014-03-14T10:55:11Z")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_1990316> "GO:0034273")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/GO_1990316> "GO:0070969")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1990316> "ATG1 kinase complex")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1990316> "ATG1-ATG13 complex")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1990316> "ATG1/ULK1 signaling complex")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1990316> "Atg1p signalling complex")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:28816597") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1990316> "ULK complex")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:26921696") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1990316> "ULK1 complex")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1990316> "ULK1 signaling complex")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1990316> "ULK1-ATG13-FIP200 complex")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1990316> "ULK1-ATG13-RB1CC1 complex")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:PARL") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:pad") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:26754330") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_1990316> "autophagy-initiation complex")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_1990316> "cellular_component")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_1990316> "GO:1990316")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_1990316> "Atg1/ULK1 kinase complex")
-SubClassOf(<http://purl.obolibrary.org/obo/GO_1990316> <http://purl.obolibrary.org/obo/GO_0032991>)
-SubClassOf(<http://purl.obolibrary.org/obo/GO_1990316> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0005737>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_1990316> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002215> <http://purl.obolibrary.org/obo/GO_0004674>))
-SubClassOf(<http://purl.obolibrary.org/obo/GO_1990316> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002216> <http://purl.obolibrary.org/obo/GO_0000045>))
-
 # Class: <http://purl.obolibrary.org/obo/GO_1990351> (transporter complex)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bhm") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:15449578") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_1990351> "A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells.")
@@ -111419,37 +109421,6 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_2000768> "positive regulation of nephron tubule epithelial cell differentiation")
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_2000768> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0072160>)))
 
-# Class: <http://purl.obolibrary.org/obo/GO_2000785> (regulation of autophagosome assembly)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:BHF") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_2000785> "Any process that modulates the frequency, rate or extent of autophagosome assembly.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_2000785> "rl")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_2000785> "2011-06-24T11:19:08Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_2000785> "regulation of autophagic vacuole assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:obol") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_2000785> "regulation of autophagosome biosynthesis")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:obol") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_2000785> "regulation of autophagosome formation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_2000785> "biological_process")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:obol") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_2000785> "regulation of PAS formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:obol") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_2000785> "regulation of autophagic vacuole formation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_2000785> "GO:2000785")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_2000785> "regulation of autophagosome assembly")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_2000785> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002211> <http://purl.obolibrary.org/obo/GO_0000045>)))
-
-# Class: <http://purl.obolibrary.org/obo/GO_2000786> (positive regulation of autophagosome assembly)
-
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:BHF") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_2000786> "Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly.")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_2000786> "rl")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_2000786> "2011-06-24T11:19:12Z")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:autophagy") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_2000786> "positive regulation of autophagic vacuole assembly")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:obol") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_2000786> "positive regulation of autophagosome biosynthesis")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:obol") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_2000786> "positive regulation of autophagosome formation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_2000786> "biological_process")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:obol") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_2000786> "positive regulation of PAS formation")
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:obol") <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> <http://purl.obolibrary.org/obo/GO_2000786> "positive regulation of autophagic vacuole formation")
-AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_2000786> "GO:2000786")
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_2000786> "positive regulation of autophagosome assembly")
-EquivalentClasses(<http://purl.obolibrary.org/obo/GO_2000786> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0000045>)))
-SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#http://purl.obolibrary.org/obo/IAO_0000233> "https://github.com/geneontology/go-ontology/issues/13926") <http://purl.obolibrary.org/obo/GO_2000786> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0016236>))
-
 # Class: <http://purl.obolibrary.org/obo/GO_2000790> (regulation of mesenchymal cell proliferation involved in lung development)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:21513708") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_2000790> "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.")
@@ -112680,106 +110651,6 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_2001259> "posi
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_2001259> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0065007> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0005261>)))
 SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#http://purl.obolibrary.org/obo/IAO_0000233> "https://github.com/geneontology/go-ontology/issues/13926") <http://purl.obolibrary.org/obo/GO_2001259> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002213> <http://purl.obolibrary.org/obo/GO_0098655>))
 
-# Class: <http://purl.obolibrary.org/obo/IAO_0000027> (data item)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000027> "data item"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000112> <http://purl.obolibrary.org/obo/IAO_0000027> "Data items include counts of things, analyte concentrations, and statistical summaries."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000114> <http://purl.obolibrary.org/obo/IAO_0000027> <http://purl.obolibrary.org/obo/IAO_0000125>)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000027> "An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000027> "2/2/2009 Alan and Bjoern discussing FACS run output data. This is a data item because it is about the cell population. Each element records an event and is typically further composed a set of measurment data items that record the fluorescent intensity stimulated by one of the lasers."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000027> "2009-03-16: data item deliberatly ambiguous: we merged data set and datum to be one entity, not knowing how to define singular versus plural. So data item is more general than datum."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000027> "2009-03-16: removed datum as alternative term as datum specifically refers to singular form, and is thus not an exact synonym."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000027> "JAR: datum     -- well, this will be very tricky to define, but maybe some 
-information-like stuff that might be put into a computer and that is 
-meant, by someone, to denote and/or to be interpreted by some 
-process... I would include lists, tables, sentences... I think I might 
-defer to Barry, or to Brian Cantwell Smith
-
-JAR: A data item is an approximately justified approximately true approximate belief"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000027> "2014-03-31: See discussion at http://odontomachus.wordpress.com/2014/03/30/aboutness-objects-propositions/")
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000027> "PERSON: Alan Ruttenberg"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000027> "PERSON: Chris Stoeckert"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000027> "PERSON: Jonathan Rees"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000118> <http://purl.obolibrary.org/obo/IAO_0000027> "data"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000027> "data item"@en)
-SubClassOf(<http://purl.obolibrary.org/obo/IAO_0000027> <http://purl.obolibrary.org/obo/IAO_0000030>)
-
-# Class: <http://purl.obolibrary.org/obo/IAO_0000028> (symbol)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000028> "symbol"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000112> <http://purl.obolibrary.org/obo/IAO_0000028> "a serial number such as \"12324X\""@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000112> <http://purl.obolibrary.org/obo/IAO_0000028> "a stop sign"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000112> <http://purl.obolibrary.org/obo/IAO_0000028> "a written proper name such as \"OBI\""@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000114> <http://purl.obolibrary.org/obo/IAO_0000028> <http://purl.obolibrary.org/obo/IAO_0000125>)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000028> "An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000028> "20091104, MC: this needs work and will most probably change"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000028> "2014-03-31: We would like to have a deeper analysis of 'mark' and 'sign' in the future (see https://github.com/information-artifact-ontology/IAO/issues/154)."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000028> "PERSON: James A. Overton"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000028> "PERSON: Jonathan Rees"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000119> <http://purl.obolibrary.org/obo/IAO_0000028> "based on Oxford English Dictionary"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000028> "symbol"@en)
-SubClassOf(<http://purl.obolibrary.org/obo/IAO_0000028> <http://purl.obolibrary.org/obo/IAO_0000030>)
-
-# Class: <http://purl.obolibrary.org/obo/IAO_0000030> (information content entity)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000030> "information content entity"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000112> <http://purl.obolibrary.org/obo/IAO_0000030> "Examples of information content entites include journal articles, data, graphical layouts, and graphs."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000114> <http://purl.obolibrary.org/obo/IAO_0000030> <http://purl.obolibrary.org/obo/IAO_0000122>)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000030> "A generically dependent continuant that is about some thing."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000030> "2014-03-10: The use of \"thing\" is intended to be general enough to include universals and configurations (see https://groups.google.com/d/msg/information-ontology/GBxvYZCk1oc/-L6B5fSBBTQJ)."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000030> "information_content_entity 'is_encoded_in' some digital_entity in obi before split (040907). information_content_entity 'is_encoded_in' some physical_document in obi before split (040907).
-
-Previous. An information content entity is a non-realizable information entity that 'is encoded in' some digital or physical entity."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000030> "PERSON: Chris Stoeckert"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000119> <http://purl.obolibrary.org/obo/IAO_0000030> "OBI_0000142"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000030> "information content entity"@en)
-SubClassOf(<http://purl.obolibrary.org/obo/IAO_0000030> <http://purl.obolibrary.org/obo/BFO_0000031>)
-SubClassOf(<http://purl.obolibrary.org/obo/IAO_0000030> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/IAO_0000136> <http://purl.obolibrary.org/obo/BFO_0000001>))
-
-# Class: <http://purl.obolibrary.org/obo/IAO_0000078> (curation status specification)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000078> "curation status specification"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000114> <http://purl.obolibrary.org/obo/IAO_0000078> <http://purl.obolibrary.org/obo/IAO_0000125>)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000078> "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000078> "Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting)"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000078> "PERSON:Bill Bug"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000119> <http://purl.obolibrary.org/obo/IAO_0000078> "GROUP:OBI:<http://purl.obolibrary.org/obo/obi>"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000119> <http://purl.obolibrary.org/obo/IAO_0000078> "OBI_0000266"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000078> "curation status specification"@en)
-EquivalentClasses(<http://purl.obolibrary.org/obo/IAO_0000078> ObjectOneOf(<http://purl.obolibrary.org/obo/IAO_0000002> <http://purl.obolibrary.org/obo/IAO_0000120> <http://purl.obolibrary.org/obo/IAO_0000121> <http://purl.obolibrary.org/obo/IAO_0000122> <http://purl.obolibrary.org/obo/IAO_0000123> <http://purl.obolibrary.org/obo/IAO_0000124> <http://purl.obolibrary.org/obo/IAO_0000125> <http://purl.obolibrary.org/obo/IAO_0000423> <http://purl.obolibrary.org/obo/IAO_0000428>))
-SubClassOf(<http://purl.obolibrary.org/obo/IAO_0000078> <http://purl.obolibrary.org/obo/IAO_0000102>)
-
-# Class: <http://purl.obolibrary.org/obo/IAO_0000102> (data about an ontology part)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000102> "data about an ontology part"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000102> "Data about an ontology part is a data item about a part of an ontology, for example a term"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000102> "Person:Alan Ruttenberg"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000102> "data about an ontology part"@en)
-SubClassOf(<http://purl.obolibrary.org/obo/IAO_0000102> <http://purl.obolibrary.org/obo/IAO_0000027>)
-
-# Class: <http://purl.obolibrary.org/obo/IAO_0000225> (obsolescence reason specification)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000225> "obsolescence reason specification"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000114> <http://purl.obolibrary.org/obo/IAO_0000225> <http://purl.obolibrary.org/obo/IAO_0000125>)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000225> "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000225> "The creation of this class has been inspired in part by Werner Ceusters' paper, Applying evolutionary terminology auditing to the Gene Ontology."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000225> "PERSON: Alan Ruttenberg"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000225> "PERSON: Melanie Courtot"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000225> "obsolescence reason specification"@en)
-EquivalentClasses(<http://purl.obolibrary.org/obo/IAO_0000225> ObjectOneOf(<http://purl.obolibrary.org/obo/IAO_0000103> <http://purl.obolibrary.org/obo/IAO_0000226> <http://purl.obolibrary.org/obo/IAO_0000227> <http://purl.obolibrary.org/obo/IAO_0000228> <http://purl.obolibrary.org/obo/IAO_0000229> <http://purl.obolibrary.org/obo/OMO_0001000>))
-SubClassOf(<http://purl.obolibrary.org/obo/IAO_0000225> <http://purl.obolibrary.org/obo/IAO_0000102>)
-
-# Class: <http://purl.obolibrary.org/obo/IAO_0000409> (denotator type)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000409> "denotator type"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000112> <http://purl.obolibrary.org/obo/IAO_0000409> "The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are \"natural kinds\" and the latter arbitrary collections of entities."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000409> "A denotator type indicates how a term should be interpreted from an ontological perspective."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000409> "Alan Ruttenberg"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000119> <http://purl.obolibrary.org/obo/IAO_0000409> "Barry Smith, Werner Ceusters"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000409> "denotator type"@en)
-EquivalentClasses(<http://purl.obolibrary.org/obo/IAO_0000409> ObjectOneOf(<http://purl.obolibrary.org/obo/IAO_0000410> <http://purl.obolibrary.org/obo/IAO_0000420> <http://purl.obolibrary.org/obo/IAO_0000421>))
-SubClassOf(<http://purl.obolibrary.org/obo/IAO_0000409> <http://purl.obolibrary.org/obo/IAO_0000102>)
-
 # Class: <http://purl.obolibrary.org/obo/NCBITaxon_1> (root)
 
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/NCBITaxon_1> "GC_ID:1")
@@ -156041,6 +153912,7 @@ SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "FMA
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "MP:0010988") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0001956> "The hyaline cartilaginous structures that support the bronchi, present as irregular rings in the larger bronchi (and not as regular as in the trachea), and as small plates and islands in the smaller bronchi; as the branching continues through the bronchial tree, the amount of hyaline cartilage in the walls decreases until it is absent in the smallest bronchioles[MP].")
 AnnotationAssertion(<http://purl.obolibrary.org/obo/RO_0002175> <http://purl.obolibrary.org/obo/UBERON_0001956> <http://purl.obolibrary.org/obo/NCBITaxon_9606>)
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/UBERON_0001956> <https://orcid.org/0000-0001-6677-8489>)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0001956> "EMAPA:35192")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0001956> "FMA:62649")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0001956> "MA:0001835")
@@ -156061,6 +153933,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <htt
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/UBERON_0001956> <http://purl.obolibrary.org/obo/uberon/core#pheno_slim>)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0001956> "cartilage of bronchus")
 EquivalentClasses(<http://purl.obolibrary.org/obo/UBERON_0001956> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/UBERON_0007844> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002185>)))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0001956> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_0019002>))
 SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0001956> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002433> <http://purl.obolibrary.org/obo/UBERON_0002185>))
 SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "MP") <http://purl.obolibrary.org/obo/UBERON_0001956> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002473> <http://purl.obolibrary.org/obo/UBERON_0001994>))
 
@@ -156094,6 +153967,7 @@ SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0001957> ObjectSomeValuesFrom(
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "http://orcid.org/0000-0002-6601-2165") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0001958> "An epithelium that lines a terminal bronchiole.")
 AnnotationAssertion(<http://purl.obolibrary.org/obo/RO_0002175> <http://purl.obolibrary.org/obo/UBERON_0001958> <http://purl.obolibrary.org/obo/NCBITaxon_9606>)
 AnnotationAssertion(<http://purl.obolibrary.org/obo/UBPROP_0000008> <http://purl.obolibrary.org/obo/UBERON_0001958> "A pseudostratified epithelium, containing basal cells, stem cells of the airway, submucosal glands and cartilage rings, is limited to the trachea and large lobar airways in the mouse (Morrisey and Hogan, 2010). This more complex epithelium extends to terminal bronchioles in the human[DOI:10.1242/dev.115469]")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/UBERON_0001958> <https://orcid.org/0000-0001-6677-8489>)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0001958> "EMAPA:36283")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0001958> "FMA:62794")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0001958> "MA:0001774")
@@ -156113,6 +153987,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <htt
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0001958> "terminal bronchiole epithelium")
 EquivalentClasses(<http://purl.obolibrary.org/obo/UBERON_0001958> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/UBERON_0000483> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002187>)))
 SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "FMA") <http://purl.obolibrary.org/obo/UBERON_0001958> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_0000158>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0001958> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_1000271>))
 
 # Class: <http://purl.obolibrary.org/obo/UBERON_0001959> (white pulp of spleen)
 
@@ -158210,6 +156085,7 @@ EquivalentClasses(<http://purl.obolibrary.org/obo/UBERON_0002050> ObjectIntersec
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "OBOL:automatic") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0002051> "An epithelium that is part of a bronchiole [Automatically generated definition].")
 AnnotationAssertion(<http://purl.obolibrary.org/obo/RO_0002175> <http://purl.obolibrary.org/obo/UBERON_0002051> <http://purl.obolibrary.org/obo/NCBITaxon_9606>)
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/UBERON_0002051> <https://orcid.org/0000-0001-6677-8489>)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0002051> "BTO:0001866")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0002051> "CALOHA:TS-0570")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0002051> "EMAPA:32693")
@@ -158230,7 +156106,9 @@ EquivalentClasses(<http://purl.obolibrary.org/obo/UBERON_0002051> ObjectIntersec
 SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002051> <http://purl.obolibrary.org/obo/UBERON_0000485>)
 SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "BTO") <http://purl.obolibrary.org/obo/UBERON_0002051> <http://purl.obolibrary.org/obo/UBERON_0004802>)
 SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002051> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0005039>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002051> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_0000158>))
 SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "FMA") <http://purl.obolibrary.org/obo/UBERON_0002051> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_0002145>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002051> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_1000271>))
 SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002051> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002433> <http://purl.obolibrary.org/obo/UBERON_0002186>))
 
 # Class: <http://purl.obolibrary.org/obo/UBERON_0002052> (adrenal gland capsule)
@@ -160661,6 +158539,7 @@ SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002184> ObjectSomeValuesFrom(
 SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002184> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/UBERON_0004242>))
 SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002184> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/UBERON_0004883>))
 SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002184> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/UBERON_8410043>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002184> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002131> <http://purl.obolibrary.org/obo/UBERON_8600017>))
 SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002184> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/uberon/core#proximally_connected_to> <http://purl.obolibrary.org/obo/UBERON_0002183>))
 
 # Class: <http://purl.obolibrary.org/obo/UBERON_0002185> (bronchus)
@@ -160734,12 +158613,11 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0002186> "
 AnnotationAssertion(<http://xmlns.com/foaf/0.1/depicted_by> <http://purl.obolibrary.org/obo/UBERON_0002186> "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png"^^xsd:anyURI)
 SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002186> <http://purl.obolibrary.org/obo/UBERON_0000117>)
 SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "MA") <http://purl.obolibrary.org/obo/UBERON_0002186> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002048>))
-SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "ncit") <http://purl.obolibrary.org/obo/UBERON_0002186> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0010368>))
 SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "FMA") <http://purl.obolibrary.org/obo/UBERON_0002186> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002380> <http://purl.obolibrary.org/obo/UBERON_0007196>))
 
 # Class: <http://purl.obolibrary.org/obo/UBERON_0002187> (terminal bronchiole)
 
-AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0-397-51047-0") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "MGI:cwg") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "MP:0002268") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0002187> "The last conducting structure of non-respiratory bronchioles; after this point, the airways have alveoli in their walls.")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0-397-51047-0") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "MGI:cwg") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "MP:0002268") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:16543587") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0002187> "A bronchiole that is part of a secondary pulmonary lobule and the last conducting structure of a non-respiratory bronchiole; after this point, the airways have alveoli in their walls.")
 AnnotationAssertion(<http://purl.obolibrary.org/obo/RO_0002175> <http://purl.obolibrary.org/obo/UBERON_0002187> <http://purl.obolibrary.org/obo/NCBITaxon_9606>)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0002187> "BTO:0003223")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0002187> "EMAPA:36282")
@@ -160760,6 +158638,9 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <htt
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0002187> "terminal bronchiole")
 AnnotationAssertion(<http://xmlns.com/foaf/0.1/depicted_by> <http://purl.obolibrary.org/obo/UBERON_0002187> "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png"^^xsd:anyURI)
 SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002187> <http://purl.obolibrary.org/obo/UBERON_0002186>)
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002187> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0010369>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002187> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/uberon/core#distally_connected_to> <http://purl.obolibrary.org/obo/UBERON_0002188>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002187> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/uberon/core#distally_connected_to> <http://purl.obolibrary.org/obo/UBERON_0008874>))
 
 # Class: <http://purl.obolibrary.org/obo/UBERON_0002188> (respiratory bronchiole)
 
@@ -163391,6 +161272,7 @@ SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002338> ObjectSomeValuesFrom(
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO:0060481") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0002339> "The tissue made up of epithelial cells that lines the inside of the lobar bronchus.")
 AnnotationAssertion(<http://purl.obolibrary.org/obo/RO_0002175> <http://purl.obolibrary.org/obo/UBERON_0002339> <http://purl.obolibrary.org/obo/NCBITaxon_9606>)
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/UBERON_0002339> <https://orcid.org/0000-0001-6677-8489>)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0002339> "EMAPA:32695")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0002339> "FMA:86624")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0002339> "MA:0001842")
@@ -163407,11 +161289,15 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/UBERON_0002339> <http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas>)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0002339> "epithelium of lobar bronchus")
 EquivalentClasses(<http://purl.obolibrary.org/obo/UBERON_0002339> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/UBERON_0000483> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002183>)))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002339> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_0002329>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002339> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_0002332>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002339> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_0017000>))
 
 # Class: <http://purl.obolibrary.org/obo/UBERON_0002341> (epithelium of segmental bronchus)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "OBOL:automatic") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0002341> "An epithelium that is part of a segmental bronchus [Automatically generated definition].")
 AnnotationAssertion(<http://purl.obolibrary.org/obo/RO_0002175> <http://purl.obolibrary.org/obo/UBERON_0002341> <http://purl.obolibrary.org/obo/NCBITaxon_9606>)
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/UBERON_0002341> <https://orcid.org/0000-0001-6677-8489>)
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "MA:th") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0002341> "EMAPA:37740")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0002341> "FMA:86626")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0002341> "MA:0001850")
@@ -163430,6 +161316,13 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0002341> "
 EquivalentClasses(<http://purl.obolibrary.org/obo/UBERON_0002341> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/UBERON_0000483> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002184>)))
 SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002341> <http://purl.obolibrary.org/obo/UBERON_0002031>)
 SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002341> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002184>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002341> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_0000158>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002341> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_0002208>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002341> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_0002329>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002341> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_0002332>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002341> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_0017000>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002341> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_1000143>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0002341> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_1000223>))
 
 # Class: <http://purl.obolibrary.org/obo/UBERON_0002342> (neural crest)
 
@@ -181247,6 +179140,7 @@ EquivalentClasses(<http://purl.obolibrary.org/obo/UBERON_0004240> ObjectIntersec
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "OBOL:automatic") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0004242> "A portion of smooth muscle tissue that is part of a bronchus [Automatically generated definition].")
 AnnotationAssertion(<http://purl.obolibrary.org/obo/RO_0002175> <http://purl.obolibrary.org/obo/UBERON_0004242> <http://purl.obolibrary.org/obo/NCBITaxon_9606>)
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/UBERON_0004242> <https://orcid.org/0000-0001-6677-8489>)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0004242> "BTO:0004401")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0004242> "EMAPA:35195")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0004242> "MA:0001840")
@@ -181281,6 +179175,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/UBERON_0004242> <http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas>)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0004242> "bronchus smooth muscle")
 EquivalentClasses(<http://purl.obolibrary.org/obo/UBERON_0004242> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/UBERON_0001135> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002185>)))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0004242> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_0002598>))
 
 # Class: <http://purl.obolibrary.org/obo/UBERON_0004243> (prostate gland smooth muscle)
 
@@ -183427,23 +181322,27 @@ EquivalentClasses(<http://purl.obolibrary.org/obo/UBERON_0004515> ObjectIntersec
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "OBOL:automatic") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0004516> "A portion of smooth muscle tissue that is part of a terminal bronchiole [Automatically generated definition].")
 AnnotationAssertion(<http://purl.obolibrary.org/obo/RO_0002175> <http://purl.obolibrary.org/obo/UBERON_0004516> <http://purl.obolibrary.org/obo/NCBITaxon_9606>)
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/UBERON_0004516> <https://orcid.org/0000-0001-6677-8489>)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0004516> "FMA:261051")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/UBERON_0004516> "uberon")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/UBERON_0004516> "UBERON:0004516")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/UBERON_0004516> <http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas>)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0004516> "smooth muscle tissue of terminal bronchiole")
 EquivalentClasses(<http://purl.obolibrary.org/obo/UBERON_0004516> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/UBERON_0001135> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002187>)))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0004516> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_4033017>))
 
 # Class: <http://purl.obolibrary.org/obo/UBERON_0004517> (smooth muscle tissue of respiratory bronchiole)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "OBOL:automatic") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0004517> "A portion of smooth muscle tissue that is part of a respiratory bronchiole [Automatically generated definition].")
 AnnotationAssertion(<http://purl.obolibrary.org/obo/RO_0002175> <http://purl.obolibrary.org/obo/UBERON_0004517> <http://purl.obolibrary.org/obo/NCBITaxon_9606>)
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/UBERON_0004517> <https://orcid.org/0000-0001-6677-8489>)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0004517> "FMA:261055")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/UBERON_0004517> "uberon")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/UBERON_0004517> "UBERON:0004517")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/UBERON_0004517> <http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas>)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0004517> "smooth muscle tissue of respiratory bronchiole")
 EquivalentClasses(<http://purl.obolibrary.org/obo/UBERON_0004517> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/UBERON_0001135> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002188>)))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0004517> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_4033017>))
 
 # Class: <http://purl.obolibrary.org/obo/UBERON_0004518> (muscle of vertebral column)
 
@@ -186968,6 +184867,7 @@ SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0004883> ObjectSomeValuesFrom(
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO:0060483") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0004884> "The mass of tissue composed of mesenchymal cells in the lobar bronchus..")
 AnnotationAssertion(<http://purl.obolibrary.org/obo/RO_0002175> <http://purl.obolibrary.org/obo/UBERON_0004884> <http://purl.obolibrary.org/obo/NCBITaxon_9606>)
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/UBERON_0004884> <https://orcid.org/0000-0001-6677-8489>)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0004884> "EMAPA:32698")
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "OBOL:automatic") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/UBERON_0004884> "mesenchyme of lobar bronchus")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/UBERON_0004884> "uberon")
@@ -186975,6 +184875,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/UBERON_0004884> <http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas>)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0004884> "lobar bronchus mesenchyme")
 EquivalentClasses(<http://purl.obolibrary.org/obo/UBERON_0004884> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/UBERON_0003104> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002183>)))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0004884> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_0019019>))
 
 # Class: <http://purl.obolibrary.org/obo/UBERON_0004889> (lobar bronchus vasculature)
 
@@ -191735,7 +189636,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <htt
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0005381> "dentate gyrus granule cell layer")
 EquivalentClasses(<http://purl.obolibrary.org/obo/UBERON_0005381> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/UBERON_0002304> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BSPO_0001107> <http://purl.obolibrary.org/obo/UBERON_0004679>)))
 SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0005381> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002131> <http://purl.obolibrary.org/obo/CL_0000118>))
-SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0005381> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002473> <http://purl.obolibrary.org/obo/CL_0000120>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0005381> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002473> <http://purl.obolibrary.org/obo/CL_2000089>))
 
 # Class: <http://purl.obolibrary.org/obo/UBERON_0005382> (dorsal striatum)
 
@@ -203315,6 +201216,7 @@ SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0008861> ObjectSomeValuesFrom(
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "MP:0010901") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0008870> "The distinguishing cell types of the lung alveolar tissue, including pulmonary epithelial cells (pneumocytes), alveolar capillary endothelial cells, interstitial cells (fibroblasts) and alveolar macrophages.")
 AnnotationAssertion(<http://purl.obolibrary.org/obo/RO_0002175> <http://purl.obolibrary.org/obo/UBERON_0008870> <http://purl.obolibrary.org/obo/NCBITaxon_9606>)
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/UBERON_0008870> <https://orcid.org/0000-0001-6677-8489>)
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "MA:th") <http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0008870> "EMAPA:37942")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/UBERON_0008870> "uberon")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/UBERON_0008870> "UBERON:0008870")
@@ -203322,6 +201224,9 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <htt
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/UBERON_0008870> <http://purl.obolibrary.org/obo/uberon/core#pheno_slim>)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0008870> "pulmonary alveolar parenchyma")
 EquivalentClasses(<http://purl.obolibrary.org/obo/UBERON_0008870> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/UBERON_0000353> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002299>)))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0008870> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_0002062>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0008870> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_0002063>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0008870> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/CL_0009089>))
 SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0008870> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002433> <http://purl.obolibrary.org/obo/UBERON_0006524>))
 
 # Class: <http://purl.obolibrary.org/obo/UBERON_0008874> (pulmonary acinus)
@@ -203344,7 +201249,8 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/UBERON_0008874> <http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas>)
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/UBERON_0008874> <http://purl.obolibrary.org/obo/uberon/core#pheno_slim>)
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0008874> "pulmonary acinus")
-SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "FMA") <http://purl.obolibrary.org/obo/UBERON_0008874> <http://purl.obolibrary.org/obo/UBERON_0010368>)
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0008874> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0010369>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0008874> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002170> <http://purl.obolibrary.org/obo/UBERON_0002187>))
 
 # Class: <http://purl.obolibrary.org/obo/UBERON_0008876> (hypodermis skeletal muscle layer)
 
@@ -208612,7 +206518,21 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/UBERON_0010368> "UBERON:0010368")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0010368> "pulmonary lobule")
 EquivalentClasses(<http://purl.obolibrary.org/obo/UBERON_0010368> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/UBERON_0009911> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002048>)))
-SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0010368> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> <http://purl.obolibrary.org/obo/UBERON_0002187>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0010368> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_8600017>))
+
+# Class: <http://purl.obolibrary.org/obo/UBERON_0010369> (secondary pulmonary lobule)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:3259815") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0010369> "A unit of lung supplied by three to five terminal bronchioles and contained by fibrous septa.")
+AnnotationAssertion(<http://purl.obolibrary.org/obo/RO_0002175> <http://purl.obolibrary.org/obo/UBERON_0010369> <http://purl.obolibrary.org/obo/NCBITaxon_9606>)
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "http://medical-dictionary.thefreedictionary.com/secondary+pulmonary+lobule") <http://purl.obolibrary.org/obo/UBPROP_0000001> <http://purl.obolibrary.org/obo/UBERON_0010369> "a pyramidal mass of lung tissue with sides that are bounded by the incomplete interlobular connective tissue septa and with a base, which is 1-2 cm in diameter, which usually faces the pleural surface of the lung; lobules that occupy a more central position in the lung are not well defined and are considered to consist of three to five pulmonary acini with proximate terminal bronchioles.")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0010369> "FMA:7414")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "FMA:7414") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "FMA:TA") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasSynonymType> <http://purl.obolibrary.org/obo/uberon/core#LATIN>) <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/UBERON_0010369> "lobulus pulmonis secondarius")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/UBERON_0010369> "uberon")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/UBERON_0010369> "UBERON:0010369")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/UBERON_0010369> <http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas>)
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0010369> "secondary pulmonary lobule")
+SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "FMA") <http://purl.obolibrary.org/obo/UBERON_0010369> <http://purl.obolibrary.org/obo/UBERON_0010368>)
+SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "FMA") <http://purl.obolibrary.org/obo/UBERON_0010369> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0008946>))
 
 # Class: <http://purl.obolibrary.org/obo/UBERON_0010370> (tibial vein)
 
@@ -224059,121 +221979,20 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_8600012> "submucosal gland acinus")
 EquivalentClasses(<http://purl.obolibrary.org/obo/UBERON_8600012> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/UBERON_0009842> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0011148>)))
 
-
-############################
-#   Named Individuals
-############################
-
-# Individual: <http://purl.obolibrary.org/obo/IAO_0000002> (example to be eventually removed)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000002> "example to be eventually removed"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000002> "example to be eventually removed"@en)
-
-# Individual: <http://purl.obolibrary.org/obo/IAO_0000103> (failed exploratory term)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000103> "failed exploratory term"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000103> "The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000103> "Person:Alan Ruttenberg"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000103> "failed exploratory term"@en)
-
-# Individual: <http://purl.obolibrary.org/obo/IAO_0000120> (metadata complete)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000120> "metadata complete"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000120> "Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete."@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000120> "metadata complete"@en)
-
-# Individual: <http://purl.obolibrary.org/obo/IAO_0000121> (organizational term)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000121> "organizational term"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000121> "Term created to ease viewing/sort terms for development purpose, and will not be included in a release"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000121> "organizational term"@en)
-
-# Individual: <http://purl.obolibrary.org/obo/IAO_0000122> (ready for release)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000122> "ready for release"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000122> "Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking \"ready_for_release\" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release.  Those classes deemed \"ready_for_release\" will also derived from a chain of ancestor classes that are also \"ready_for_release.\""@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000122> "ready for release"@en)
-
-# Individual: <http://purl.obolibrary.org/obo/IAO_0000123> (metadata incomplete)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000123> "metadata incomplete"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000123> "Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors."@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000123> "metadata incomplete"@en)
-
-# Individual: <http://purl.obolibrary.org/obo/IAO_0000124> (uncurated)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000124> "uncurated"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000124> "Nothing done yet beyond assigning a unique class ID and proposing a preferred term."@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000124> "uncurated"@en)
-
-# Individual: <http://purl.obolibrary.org/obo/IAO_0000125> (pending final vetting)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000125> "pending final vetting"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000125> "All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor."@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000125> "pending final vetting"@en)
-
-# Individual: <http://purl.obolibrary.org/obo/IAO_0000226> (placeholder removed)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000226> "placeholder removed"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000226> "placeholder removed"@en)
-
-# Individual: <http://purl.obolibrary.org/obo/IAO_0000227> (terms merged)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000227> "terms merged"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000227> "An editor note should explain what were the merged terms and the reason for the merge."@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000227> "terms merged"@en)
-
-# Individual: <http://purl.obolibrary.org/obo/IAO_0000228> (term imported)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000228> "term imported"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000228> "This is to be used when the original term has been replaced by a term imported from an other ontology. An editor note should indicate what is the URI of the new term to use."@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000228> "term imported"@en)
-
-# Individual: <http://purl.obolibrary.org/obo/IAO_0000229> (term split)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000229> "term split"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000229> "This is to be used when a term has been split in two or more new terms. An editor note should indicate the reason for the split and indicate the URIs of the new terms created."@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000229> "term split"@en)
-
-# Individual: <http://purl.obolibrary.org/obo/IAO_0000410> (universal)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000410> "universal"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000410> "Hard to give a definition for. Intuitively a \"natural kind\" rather than a collection of any old things, which a class is able to be, formally. At the meta level, universals are defined as positives, are disjoint with their siblings, have single asserted parents."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000410> "Alan Ruttenberg"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000119> <http://purl.obolibrary.org/obo/IAO_0000410> "A Formal Theory of Substances, Qualities, and Universals, http://ontology.buffalo.edu/bfo/SQU.pdf"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000410> "universal"@en)
-
-# Individual: <http://purl.obolibrary.org/obo/IAO_0000420> (defined class)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000420> "defined class"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000420> "A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000420> "\"definitions\", in some readings, always are given by necessary and sufficient conditions. So one must be careful (and this is difficult sometimes) to distinguish between defined classes and universal."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000420> "Alan Ruttenberg"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000420> "defined class"@en)
-
-# Individual: <http://purl.obolibrary.org/obo/IAO_0000421> (named class expression)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000421> "named class expression"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000421> "A named class expression is a logical expression that is given a name. The name can be used in place of the expression."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000116> <http://purl.obolibrary.org/obo/IAO_0000421> "named class expressions are used in order to have more concise logical definition but their extensions may not be interesting classes on their own. In languages such as OWL, with no provisions for macros, these show up as actuall classes. Tools may with to not show them as such, and to replace uses of the macros with their expansions"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000421> "Alan Ruttenberg"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000421> "named class expression"@en)
-
-# Individual: <http://purl.obolibrary.org/obo/IAO_0000423> (to be replaced with external ontology term)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000423> "to be replaced with external ontology term"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000423> "Terms with this status should eventually replaced with a term from another ontology."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000423> "Alan Ruttenberg"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000119> <http://purl.obolibrary.org/obo/IAO_0000423> "group:OBI"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000423> "to be replaced with external ontology term"@en)
-
-# Individual: <http://purl.obolibrary.org/obo/IAO_0000428> (requires discussion)
-
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000111> <http://purl.obolibrary.org/obo/IAO_0000428> "requires discussion"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/IAO_0000428> "A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues."@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000117> <http://purl.obolibrary.org/obo/IAO_0000428> "Alan Ruttenberg"@en)
-AnnotationAssertion(<http://purl.obolibrary.org/obo/IAO_0000119> <http://purl.obolibrary.org/obo/IAO_0000428> "group:OBI"@en)
-AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/IAO_0000428> "requires discussion"@en)
+# Class: <http://purl.obolibrary.org/obo/UBERON_8600017> (bronchopulmonary segment)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "FMA:7312") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:18271171") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:33620799") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "doi:10.1016/j.mpaic.2008.09.022") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_8600017> "A discrete anatomical unit of the lung that is composed of a segmental bronchus and the lung tissue supplied by that bronchus. A bronchopulmonary segment exhibits a pyramidal shape, with its apex pointing towards the center of the lung and its base toward the pleural surface.")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/UBERON_8600017> <https://orcid.org/0000-0001-6677-8489>)
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/UBERON_8600017> <https://orcid.org/0000-0002-9185-3994>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> <http://purl.obolibrary.org/obo/UBERON_8600017> "2023-07-20T12:43:29Z"^^xsd:dateTime)
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:33620799") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/UBERON_8600017> "lung segment")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/UBERON_8600017> "uberon")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/UBERON_8600017> "UBERON:8600017")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "PMID:18271171") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "doi:10.1016/j.mpaic.2008.09.022") rdfs:comment <http://purl.obolibrary.org/obo/UBERON_8600017> "A bronchopulmonary segment is surrounded by connective tissue septa, which are continuous with the pleural surface and prevent air collateralization between segments somewhat. In humans, the right lung has ten bronchopulmonary segments and eight or nine bronchopulmonary segments in the left lung.")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_8600017> "bronchopulmonary segment")
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_8600017> <http://purl.obolibrary.org/obo/UBERON_0000063>)
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_8600017> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0000101>))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_8600017> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002433> <http://purl.obolibrary.org/obo/UBERON_0000101>))
 
 
 EquivalentClasses(ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CARO_0000000> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000053> <http://purl.obolibrary.org/obo/PATO_0001993>)) ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CARO_0000000> ObjectMinCardinality(2 <http://purl.obolibrary.org/obo/RO_0002180> <http://purl.obolibrary.org/obo/CL_0000000>)))