diff --git a/eng/pipelines/coreclr/templates/helix-queues-setup.yml b/eng/pipelines/coreclr/templates/helix-queues-setup.yml
index 0a2a4c4ffce9f..201bead890628 100644
--- a/eng/pipelines/coreclr/templates/helix-queues-setup.yml
+++ b/eng/pipelines/coreclr/templates/helix-queues-setup.yml
@@ -77,23 +77,23 @@ jobs:
     # Linux musl x64
     - ${{ if eq(parameters.platform, 'linux_musl_x64') }}:
       - ${{ if eq(variables['System.TeamProject'], 'public') }}:
-        - (Alpine.320.Amd64.Open)Ubuntu.2204.Amd64.Open@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.20-helix-amd64
+        - (Alpine.321.Amd64.Open)Ubuntu.2204.Amd64.Open@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.21-helix-amd64
       - ${{ if eq(variables['System.TeamProject'], 'internal') }}:
-        - (Alpine.320.Amd64)Ubuntu.2204.Amd64@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.20-helix-amd64
+        - (Alpine.321.Amd64)Ubuntu.2204.Amd64@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.21-helix-amd64
 
     # Linux musl arm32
     - ${{ if eq(parameters.platform, 'linux_musl_arm') }}:
       - ${{ if eq(variables['System.TeamProject'], 'public') }}:
-        - (Alpine.320.Arm32.Open)Ubuntu.2204.ArmArch.Open@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.20-helix-arm32v7
+        - (Alpine.321.Arm32.Open)Ubuntu.2204.ArmArch.Open@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.21-helix-arm32v7
       - ${{ if eq(variables['System.TeamProject'], 'internal') }}:
-        - (Alpine.320.Arm32)Ubuntu.2204.ArmArch@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.20-helix-arm32v7
+        - (Alpine.321.Arm32)Ubuntu.2204.ArmArch@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.21-helix-arm32v7
 
     # Linux musl arm64
     - ${{ if eq(parameters.platform, 'linux_musl_arm64') }}:
       - ${{ if eq(variables['System.TeamProject'], 'public') }}:
-        - (Alpine.320.Arm64.Open)Ubuntu.2204.ArmArch.Open@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.20-helix-arm64v8
+        - (Alpine.321.Arm64.Open)Ubuntu.2204.ArmArch.Open@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.21-helix-arm64v8
       - ${{ if eq(variables['System.TeamProject'], 'internal') }}:
-        - (Alpine.320.Arm64)Ubuntu.2204.ArmArch@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.20-helix-arm64v8
+        - (Alpine.321.Arm64)Ubuntu.2204.ArmArch@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.21-helix-arm64v8
 
     # Linux x64
     - ${{ if eq(parameters.platform, 'linux_x64') }}:
diff --git a/eng/pipelines/libraries/helix-queues-setup.yml b/eng/pipelines/libraries/helix-queues-setup.yml
index 5786951f55060..42de807c32dbd 100644
--- a/eng/pipelines/libraries/helix-queues-setup.yml
+++ b/eng/pipelines/libraries/helix-queues-setup.yml
@@ -41,15 +41,13 @@ jobs:
     # Linux musl x64
     - ${{ if eq(parameters.platform, 'linux_musl_x64') }}:
       - ${{ if or(ne(parameters.jobParameters.isExtraPlatformsBuild, true), eq(parameters.jobParameters.includeAllPlatforms, true)) }}:
-        - (Alpine.320.Amd64.Open)Ubuntu.2204.Amd64.Open@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.20-helix-amd64
+        - (Alpine.321.Amd64.Open)Ubuntu.2204.Amd64.Open@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.21-helix-amd64
       - ${{ if or(eq(parameters.jobParameters.isExtraPlatformsBuild, true), eq(parameters.jobParameters.includeAllPlatforms, true)) }}:
-        - (Alpine.320.Amd64.Open)Ubuntu.2204.Amd64.Open@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.20-helix-amd64
-        - (Alpine.318.Amd64.Open)Ubuntu.2204.Amd64.Open@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.18-helix-amd64
+        - (Alpine.321.Amd64.Open)Ubuntu.2204.Amd64.Open@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.21-helix-amd64
 
     # Linux musl arm64
     - ${{ if and(eq(parameters.platform, 'linux_musl_arm64'), or(eq(parameters.jobParameters.isExtraPlatformsBuild, true), eq(parameters.jobParameters.includeAllPlatforms, true))) }}:
-      - (Alpine.320.Arm64.Open)ubuntu.2204.armarch.open@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.20-helix-arm64v8
-      - (Alpine.318.Arm64.Open)ubuntu.2204.armarch.open@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.18-helix-arm64v8
+      - (Alpine.321.Arm64.Open)ubuntu.2204.armarch.open@mcr.microsoft.com/dotnet-buildtools/prereqs:alpine-3.21-helix-arm64v8
 
     # Linux x64
     - ${{ if eq(parameters.platform, 'linux_x64') }}:
@@ -66,7 +64,6 @@ jobs:
             - (Fedora.41.Amd64.Open)ubuntu.2204.amd64.open@mcr.microsoft.com/dotnet-buildtools/prereqs:fedora-41-helix
             - Ubuntu.2204.Amd64.Open
             - (Debian.12.Amd64.Open)Ubuntu.2204.Amd64.Open@mcr.microsoft.com/dotnet-buildtools/prereqs:debian-12-helix-amd64
-            - (Mariner.2.0.Amd64.Open)Ubuntu.2204.Amd64.open@mcr.microsoft.com/dotnet-buildtools/prereqs:cbl-mariner-2.0-helix-amd64
             - (AzureLinux.3.0.Amd64.Open)Ubuntu.2204.Amd64.open@mcr.microsoft.com/dotnet-buildtools/prereqs:azurelinux-3.0-helix-amd64
             - (openSUSE.15.2.Amd64.Open)Ubuntu.2204.Amd64.open@mcr.microsoft.com/dotnet-buildtools/prereqs:opensuse-15.2-helix-amd64
           - ${{ if or(ne(parameters.jobParameters.isExtraPlatformsBuild, true), eq(parameters.jobParameters.includeAllPlatforms, true)) }}: