EPLMI

Author: Yu-An Huang, Keith C.C. Chan1,Zhu-Hong You Paper: Constructing Prediction Models from Expression Profiles for Large Scale lncRNA-miRNA Interaction Profiling

File description

Data:

Expression_profile_data: invalid_association_expression.m: The ids of known lncRNA-miRNA interactions without either of lncRNA and miRNA expression profiles. invalid_lnc_expression.m: The ids of lncRNAs without lncRNA expression profiles. invalid_mi_expression.m: The ids of lncRNAs without lncRNA expression profiles. Known_lncRNA_miRNA_association.m: The id pairs of known lncRNA-miRNA interactions. lnc_expression_similarity_matrix.m: The lncRNA-lncRNA similarity matrix of expression profiles. mi_expression_similarity_matrix.m: The miRNA-miRNA similarity matrix of expression profiles.

Function_data: invalid_association_function.m: The ids of known lncRNA-miRNA interactions without either of lncRNA and miRNA function feature. invalid_lnc_function.m: The ids of lncRNAs without lncRNA function feature. invalid_mi_function.m: The ids of lncRNAs without lncRNA function feature. Known_lncRNA_miRNA_association.m: The id pairs of known lncRNA-miRNA interactions. lnc_function_similarity_matrix.m: The lncRNA-lncRNA similarity matrix of function. mi_function_similarity_matrix.m: The miRNA-miRNA similarity matrix of function.

Sequence_data: invalid_lnc_seq.m: The ids of lncRNAs without lncRNA sequence information. Known_lncRNA_miRNA_association.m: The id pairs of known lncRNA-miRNA interactions. lnc_seq_similarity_matrix.m: The lncRNA-lncRNA similarity matrix of sequence. mi_seq_similarity_matrix.m: The miRNA-miRNA similarity matrix of sequence.

lncRNA-miRNA_interaction: lncRNA_id.m The id list of lncRNA name. miRNA_id.m The id list of miRNA name. lncRNA-miRNA_idlist.m: The lncRNA-miRNA interaction data downloaded from lncRNASNP.

Cross_validation: leave-one-out_CV: EPLMI_LOOCV.m: The codes for the implemention of leave-one-out cross validation. Plot_roc_curve: The codes for plotting the ROC curves based on the LOOCV results.

5-fold_CV: main.m: The main program for the implemention of 5-fold cross validation. Generate_random_roder_5fold.m: The codes for generating the random sample lists. EPLMI5cv: The subprogram for the implemention of 5-fold cross validation. Position2AUC.m: The codes for plotting the ROC curves based on the ranks of testing samples.