diff --git a/Makefile b/Makefile
index d14dbea2..3267c287 100644
--- a/Makefile
+++ b/Makefile
@@ -19,6 +19,18 @@ OCI_BIN ?= docker
 
 # tools
 GITHUB_RELEASE ?= $(GOBIN)/github-release
+PLATFORM_LIST ?= linux/amd64,linux/s390x,linux/arm64
+ARCH := $(shell uname -m | sed 's/x86_64/amd64/;s/aarch64/arm64/')
+PLATFORMS ?= linux/${ARCH}
+PLATFORMS := $(if $(filter all,$(PLATFORMS)),$(PLATFORM_LIST),$(PLATFORMS))
+# Set the platforms for building a multi-platform supported image.
+# Example:
+# PLATFORMS ?= linux/amd64,linux/arm64,linux/s390x
+# Alternatively, you can export the PLATFORMS variable like this:
+# export PLATFORMS=linux/arm64,linux/s390x,linux/amd64
+# or export PLATFORMS=all to automatically include all supported platforms.
+DOCKER_BUILDER ?= macvtap-docker-builder
+MACVTAP_IMAGE_TAGGED := ${IMAGE_REGISTRY}/${IMAGE_NAME}:${IMAGE_TAG}
 
 # Make does not offer a recursive wildcard function, so here's one:
 rwildcard=$(wildcard $1$2) $(foreach d,$(wildcard $1*),$(call rwildcard,$d/,$2))
@@ -30,7 +42,7 @@ go_sources=$(call rwildcard,cmd/,*.go) $(call rwildcard,pkg/,*.go) $(call rwildc
 
 # Configure Go
 export GOOS=linux
-export GOARCH=amd64
+export GOARCH=$(shell uname -m | sed 's/x86_64/amd64/;s/aarch64/arm64/')
 export CGO_ENABLED=0
 export GO111MODULE=on
 export GOFLAGS=-mod=vendor
@@ -69,17 +81,21 @@ vet: $(go_sources) $(GO)
 	$(GO) vet ./pkg/... ./cmd/... ./tests/...
 
 docker-build:
-	$(OCI_BIN) build -t ${IMAGE_REGISTRY}/${IMAGE_NAME}:${IMAGE_TAG} -f ./cmd/Dockerfile .
+ifeq ($(OCI_BIN),podman)
+	$(MAKE) build-multiarch-macvtap-podman
+else ifeq ($(OCI_BIN),docker)
+	$(MAKE) build-multiarch-macvtap-docker
+else
+	$(error Unsupported OCI_BIN value: $(OCI_BIN))
+endif
 
 docker-push:
 ifeq ($(OCI_BIN),podman)
-	$(OCI_BIN) push --tls-verify=false ${IMAGE_REGISTRY}/${IMAGE_NAME}:${IMAGE_TAG}
-else
-	$(OCI_BIN) push ${IMAGE_REGISTRY}/${IMAGE_NAME}:${IMAGE_TAG}
+	podman manifest push --tls-verify=false ${MACVTAP_IMAGE_TAGGED} ${MACVTAP_IMAGE_TAGGED}
 endif
 
 docker-tag-latest:
-	$(OCI_BIN) tag ${IMAGE_REGISTRY}/${IMAGE_NAME}:latest ${IMAGE_REGISTRY}/${IMAGE_NAME}:${IMAGE_TAG}
+	$(OCI_BIN) tag ${IMAGE_REGISTRY}/${IMAGE_NAME}:latest ${MACVTAP_IMAGE_TAGGED}
 
 cluster-up:
 	./cluster/up.sh
@@ -122,8 +138,16 @@ release: docker-build docker-push
 release: $(GITHUB_RELEASE)
 	TAG=$(IMAGE_TAG) GITHUB_RELEASE=$(GITHUB_RELEASE) DESCRIPTION=./version/description ./hack/release.sh
 
+build-multiarch-macvtap-docker:
+	PLATFORMS=$(PLATFORMS) MACVTAP_IMAGE_TAGGED=$(MACVTAP_IMAGE_TAGGED) DOCKER_BUILDER=$(DOCKER_BUILDER) ./hack/build-macvtap-docker.sh
+
+build-multiarch-macvtap-podman:
+	PLATFORMS=$(PLATFORMS) MACVTAP_IMAGE_TAGGED=$(MACVTAP_IMAGE_TAGGED) ./hack/build-macvtap-podman.sh
+
 .PHONY: \
 	all \
+	build-multiarch-macvtap-docker \
+	build-multiarch-macvtap-podman \
 	check \
 	cluster-up \
 	cluster-down \
diff --git a/automation/publish.sh b/automation/publish.sh
index ee9bb8fd..3d9d319b 100755
--- a/automation/publish.sh
+++ b/automation/publish.sh
@@ -11,6 +11,7 @@
 source automation/check-patch.setup.sh
 cd ${TMP_PROJECT_PATH}
 
+export PLATFORMS=all
 IMAGE_TAG=${IMAGE_TAG:-$(git log -1 --pretty=%h)-$(date +%s)}
 make docker-build 
 make docker-tag-latest
diff --git a/cmd/Dockerfile b/cmd/Dockerfile
index 50c52c2e..d9cdc7a9 100644
--- a/cmd/Dockerfile
+++ b/cmd/Dockerfile
@@ -1,12 +1,20 @@
 # Multi-stage dockerfile building a container image with both binaries included
 
-FROM quay.io/projectquay/golang:1.20 as builder
+FROM --platform=$BUILDPLATFORM quay.io/projectquay/golang:1.20 AS builder
 ENV GOPATH=/go
 WORKDIR /go/src/github.com/kubevirt/macvtap-cni
+ARG TARGETOS
+ARG TARGETARCH
+ENV TARGETOS=${TARGETOS:-linux}
+ENV TARGETARCH=${TARGETARCH:-amd64}
+
+ENV GOOS=${TARGETOS}
+ENV GOARCH=${TARGETARCH}
+
 COPY . .
 RUN GOOS=linux CGO_ENABLED=0 go build -o /macvtap-deviceplugin github.com/kubevirt/macvtap-cni/cmd/deviceplugin
 RUN GOOS=linux CGO_ENABLED=0 go build -o /macvtap-cni github.com/kubevirt/macvtap-cni/cmd/cni
 
-FROM registry.access.redhat.com/ubi8/ubi-minimal
+FROM --platform=linux/${TARGETARCH} registry.access.redhat.com/ubi8/ubi-minimal
 COPY --from=builder /macvtap-deviceplugin /macvtap-deviceplugin
 COPY --from=builder /macvtap-cni /macvtap-cni
diff --git a/hack/build-macvtap-docker.sh b/hack/build-macvtap-docker.sh
new file mode 100755
index 00000000..cdacb140
--- /dev/null
+++ b/hack/build-macvtap-docker.sh
@@ -0,0 +1,18 @@
+#!/usr/bin/env bash
+
+if [ -z "$PLATFORMS" ] || [ -z "$MACVTAP_IMAGE_TAGGED" ]; then
+    echo "Error: PLATFORMS, and MACVTAP_IMAGE_TAGGED must be set."
+    exit 1
+fi
+
+IFS=',' read -r -a PLATFORM_LIST <<< "$PLATFORMS"
+
+BUILD_ARGS="-f cmd/Dockerfile -t $MACVTAP_IMAGE_TAGGED . --push"
+
+if [ ${#PLATFORM_LIST[@]} -eq 1 ]; then
+    docker build --platform "$PLATFORMS" $BUILD_ARGS
+else
+    ./hack/init-buildx.sh "$DOCKER_BUILDER"
+    docker buildx build --platform "$PLATFORMS" $BUILD_ARGS
+    docker buildx rm "$DOCKER_BUILDER" 2>/dev/null || echo "Builder ${DOCKER_BUILDER} not found or already removed, skipping."
+fi
diff --git a/hack/build-macvtap-podman.sh b/hack/build-macvtap-podman.sh
new file mode 100755
index 00000000..2bdfd3f9
--- /dev/null
+++ b/hack/build-macvtap-podman.sh
@@ -0,0 +1,22 @@
+#!/usr/bin/env bash
+
+if [ -z "$PLATFORMS" ] || [ -z "$MACVTAP_IMAGE_TAGGED" ]; then
+    echo "Error: PLATFORMS, and MACVTAP_IMAGE_TAGGED must be set."
+    exit 1
+fi
+
+IFS=',' read -r -a PLATFORM_LIST <<< "$PLATFORMS"
+
+podman manifest rm "${MACVTAP_IMAGE_TAGGED}" 2>/dev/null || true
+podman manifest rm "${MARKER_IMAGE_GIT_TAGGED}" 2>/dev/null || true
+podman rmi "${MACVTAP_IMAGE_TAGGED}" 2>/dev/null || true
+podman rmi "${MARKER_IMAGE_GIT_TAGGED}" 2>/dev/null || true
+
+podman manifest create "${MACVTAP_IMAGE_TAGGED}"
+
+for platform in "${PLATFORM_LIST[@]}"; do
+    podman build \
+        --platform "$platform" \
+        --manifest "${MACVTAP_IMAGE_TAGGED}" \
+        -f cmd/Dockerfile .
+done
diff --git a/hack/init-buildx.sh b/hack/init-buildx.sh
new file mode 100755
index 00000000..16cb71c8
--- /dev/null
+++ b/hack/init-buildx.sh
@@ -0,0 +1,56 @@
+#!/usr/bin/env bash
+
+check_buildx() {
+  export DOCKER_CLI_EXPERIMENTAL=enabled
+
+  if ! docker buildx > /dev/null 2>&1; then
+     mkdir -p ~/.docker/cli-plugins
+     BUILDX_VERSION=$(curl -s https://api.github.com/repos/docker/buildx/releases/latest | jq -r .tag_name)
+     ARCH=$(uname -m | sed 's/x86_64/amd64/;s/aarch64/arm64/')
+     curl -L https://github.com/docker/buildx/releases/download/"${BUILDX_VERSION}"/buildx-"${BUILDX_VERSION}".linux-"${ARCH}" --output ~/.docker/cli-plugins/docker-buildx
+     chmod a+x ~/.docker/cli-plugins/docker-buildx
+  fi
+}
+
+create_or_use_buildx_builder() {
+  local builder_name=$1
+  if [ -z "$builder_name" ]; then
+    echo "Error: Builder name is required."
+    exit 1
+  fi
+
+  check_buildx
+
+  current_builder="$(docker buildx inspect "${builder_name}" 2>/dev/null)" || echo "Builder '${builder_name}' not found"
+
+  if ! grep -q "^Driver: docker$" <<<"${current_builder}" && \
+     grep -q "linux/amd64" <<<"${current_builder}" && \
+     grep -q "linux/arm64" <<<"${current_builder}" && \
+     grep -q "linux/s390x" <<<"${current_builder}"; then
+    echo "The current builder already has multi-architecture support (amd64, arm64, s390x)."
+    echo "Skipping setup as the builder is already configured correctly."
+    exit 0
+  fi
+
+  # Check if the builder already exists by parsing the output of `docker buildx ls`
+  # We check if the builder_name appears in the list of active builders
+  existing_builder=$(docker buildx ls | grep -w "$builder_name" | awk '{print $1}')
+
+  if [ -n "$existing_builder" ]; then
+    echo "Builder '$builder_name' already exists."
+    echo "Using existing builder '$builder_name'."
+    docker buildx use "$builder_name"
+  else
+    echo "Creating a new Docker Buildx builder: $builder_name"
+    docker buildx create --driver-opt network=host --use --name "$builder_name"
+    echo "The new builder '$builder_name' has been created and set as active."
+  fi
+}
+
+if [ $# -eq 1 ]; then
+  create_or_use_buildx_builder "$1"
+else
+  echo "Usage: $0 <builder_name>"
+  echo "Example: $0 mybuilder"
+  exit 1
+fi