diff --git a/.github/workflows/docker-release.yaml b/.github/workflows/docker-release.yaml
index c7e9ee6e..16dc93f2 100644
--- a/.github/workflows/docker-release.yaml
+++ b/.github/workflows/docker-release.yaml
@@ -11,10 +11,10 @@ jobs:
       fail-fast: false
       max-parallel: 4
       matrix:
-        dse-version: [6.8.25, 6.8.26, 6.8.28, 6.8.29, 6.8.30, 6.8.31, 6.8.32, 6.8.33, 6.8.34, 6.8.35, 6.8.36, 6.8.37, 6.8.38, 6.8.39, 6.8.40, 6.8.41, 6.8.42, 6.8.43, 6.8.44, 6.8.46, 6.8.47, 6.8.48]
+        dse-version: [6.8.25, 6.8.26, 6.8.28, 6.8.29, 6.8.30, 6.8.31, 6.8.32, 6.8.33, 6.8.34, 6.8.35, 6.8.36, 6.8.37, 6.8.38, 6.8.39, 6.8.40, 6.8.41, 6.8.42, 6.8.43, 6.8.44, 6.8.46, 6.8.47, 6.8.48, 6.8.49]
         image-base: [jdk8, jdk11]
         include:
-          - dse-version: 6.8.48
+          - dse-version: 6.8.49
             latest: true
     runs-on: ubuntu-latest
     steps:
@@ -108,10 +108,10 @@ jobs:
       fail-fast: false
       max-parallel: 4
       matrix:
-        dse-version: [6.8.25, 6.8.26, 6.8.28, 6.8.29, 6.8.30, 6.8.31, 6.8.32, 6.8.33, 6.8.34, 6.8.35, 6.8.36, 6.8.37, 6.8.38, 6.8.39, 6.8.40, 6.8.41, 6.8.42, 6.8.43, 6.8.44, 6.8.46, 6.8.47, 6.8.48]
+        dse-version: [6.8.25, 6.8.26, 6.8.28, 6.8.29, 6.8.30, 6.8.31, 6.8.32, 6.8.33, 6.8.34, 6.8.35, 6.8.36, 6.8.37, 6.8.38, 6.8.39, 6.8.40, 6.8.41, 6.8.42, 6.8.43, 6.8.44, 6.8.46, 6.8.47, 6.8.48, 6.8.49]
         image-base: [ubi8]
         include:
-          - dse-version: 6.8.48
+          - dse-version: 6.8.49
             latest: true
     runs-on: ubuntu-latest
     steps:
diff --git a/CHANGELOG.md b/CHANGELOG.md
index ed282d02..8c0d25a4 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -12,6 +12,7 @@ Changelog for Management API, new PRs should update the `main / unreleased` sect
 ## unreleased
 
 ## v0.1.81 (2024-06-13)
+* [FEATURE] [#497](https://github.com/k8ssandra/management-api-for-apache-cassandra/issues/497) Add DSE 6.8.49 to the build matrix
 * [BUGFIX] [#502](https://github.com/k8ssandra/management-api-for-apache-cassandra/issues/502) Fix DSE 6.9 UBI image builds
 * [BUGFIX] [#493](https://github.com/k8ssandra/management-api-for-apache-cassandra/issues/493) Fix nodetool in UBI based images
 
diff --git a/README.md b/README.md
index 0c51f8a7..b4613c76 100644
--- a/README.md
+++ b/README.md
@@ -78,6 +78,7 @@ The following versions of Cassandra and DSE are published to Docker and supporte
 |                  |                 |                 | 6.8.46    |               |
 |                  |                 |                 | 6.8.47    |               |
 |                  |                 |                 | 6.8.48    |               |
+|                  |                 |                 | 6.8.49    |               |
 
 - Apache Cassandra images are available in `linux/amd64` or `linux/arm64` formats. The DSE images are available only in the `linux/amd64` format.
 - All images (with the exception of Cassandra trunk) are available as an Ubuntu based image or a RedHat UBI 8 based image.
diff --git a/dse/Dockerfile-dse68.jdk11 b/dse/Dockerfile-dse68.jdk11
index 8feab3b0..e601dc67 100644
--- a/dse/Dockerfile-dse68.jdk11
+++ b/dse/Dockerfile-dse68.jdk11
@@ -10,7 +10,7 @@ ENV DSE_HOME /opt/dse
 ENV DSE_AGENT_HOME /opt/agent
 
 # Get commandline parameters
-ARG DSE_VERSION=6.8.48
+ARG DSE_VERSION=6.8.49
 ARG URL_PREFIX=https://downloads.datastax.com/enterprise
 ARG TARBALL=dse-${DSE_VERSION}-bin.tar.gz
 ARG DOWNLOAD_URL=${URL_PREFIX}/${TARBALL}
diff --git a/dse/Dockerfile-dse68.jdk8 b/dse/Dockerfile-dse68.jdk8
index 0684a65b..8bc41fac 100644
--- a/dse/Dockerfile-dse68.jdk8
+++ b/dse/Dockerfile-dse68.jdk8
@@ -10,7 +10,7 @@ ENV DSE_HOME /opt/dse
 ENV DSE_AGENT_HOME /opt/agent
 
 # Get commandline parameters
-ARG DSE_VERSION=6.8.48
+ARG DSE_VERSION=6.8.49
 ARG URL_PREFIX=https://downloads.datastax.com/enterprise
 ARG TARBALL=dse-${DSE_VERSION}-bin.tar.gz
 ARG DOWNLOAD_URL=${URL_PREFIX}/${TARBALL}
diff --git a/dse/Dockerfile-dse68.ubi8 b/dse/Dockerfile-dse68.ubi8
index e1aca4d2..28a6e0fa 100644
--- a/dse/Dockerfile-dse68.ubi8
+++ b/dse/Dockerfile-dse68.ubi8
@@ -1,4 +1,4 @@
-ARG DSE_VERSION=6.8.48
+ARG DSE_VERSION=6.8.49
 ARG UBI_MAJOR=8
 ARG UBI_BASETAG=latest
 
diff --git a/management-api-agent-dse-6.8/pom.xml b/management-api-agent-dse-6.8/pom.xml
index 7cffc469..96fc86b9 100644
--- a/management-api-agent-dse-6.8/pom.xml
+++ b/management-api-agent-dse-6.8/pom.xml
@@ -30,7 +30,7 @@
     </repository>
   </repositories>
   <properties>
-    <dse.version>6.8.48</dse.version>
+    <dse.version>6.8.49</dse.version>
   </properties>
   <dependencies>
     <dependency>
diff --git a/management-api-agent-dse-6.9/pom.xml b/management-api-agent-dse-6.9/pom.xml
index 04fb06e6..18c152a2 100644
--- a/management-api-agent-dse-6.9/pom.xml
+++ b/management-api-agent-dse-6.9/pom.xml
@@ -30,7 +30,7 @@
     </repository>
   </repositories>
   <properties>
-    <dse.version>6.8.48</dse.version>
+    <dse.version>6.8.49</dse.version>
   </properties>
   <dependencies>
     <dependency>