diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index 0416b3ae4cfdf2..3760405ee0c11d 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -23,7 +23,7 @@ bluetooth-data-tools==1.19.0
 cached_ipaddress==0.3.0
 certifi>=2021.5.30
 ciso8601==2.3.1
-cryptography==42.0.5
+cryptography==43.0.1
 dbus-fast==2.21.3
 fnv-hash-fast==0.5.0
 ha-av==10.1.1
diff --git a/pyproject.toml b/pyproject.toml
index d52b605393b842..71ebdf031fdde3 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -50,7 +50,7 @@ dependencies    = [
     "lru-dict==1.3.0",
     "PyJWT==2.8.0",
     # PyJWT has loose dependency. We want the latest one.
-    "cryptography==42.0.5",
+    "cryptography==43.0.1",
     "Pillow==10.3.0",
     "pyOpenSSL==24.1.0",
     "orjson==3.10.3",
diff --git a/requirements.txt b/requirements.txt
index d77962d64d75a6..077ee100a61c90 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -25,7 +25,7 @@ ifaddr==0.2.0
 Jinja2==3.1.4
 lru-dict==1.3.0
 PyJWT==2.8.0
-cryptography==42.0.5
+cryptography==43.0.1
 Pillow==10.3.0
 pyOpenSSL==24.1.0
 orjson==3.10.3