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<!DOCTYPE html>
<html>
<head>
<meta charset="utf-8">
<title>Bodylight.js</title>
<meta name="viewport" content="width=device-width, initial-scale=1">
<!--script src="scripts/bodylight.bundle.js" data-main="aurelia-bootstrapper"></script-->
<!--script src="https://cdn.jsdelivr.net/npm/bodylight-components/dist/bodylight.bundle.js" data-main="aurelia-bootstrapper"></script-->
<link rel="stylesheet" href="https://www.w3schools.com/w3css/4/w3.css">
<!-- Google tag (gtag.js) -->
<script async src="https://www.googletagmanager.com/gtag/js?id=G-BQLQED00TM"></script>
<script>
window.dataLayer = window.dataLayer || [];
function gtag(){dataLayer.push(arguments);}
gtag('js', new Date());
gtag('config', 'G-BQLQED00TM');
</script>
</head>
<body aurelia-app="webcomponents">
<header class="w3-bar" style="position: sticky;top: 0;background:#4a4a4a;color:white;">
<a class="w3-bar-item w3-button w3-left" href="index.html" title="creative physiome" target="_self">Home</a>
<a class="w3-bar-item w3-button w3-right" href="/Bodylight-docs/reference/">Docs</a>
<a class="w3-bar-item w3-button w3-right" href="https://egolem.online/about.html">About</a>
<a class="w3-bar-item w3-button w3-right" href="https://egolem.online/demo/" title="egolem online portal">Demos</a>
</header>
<h1 class="w3-center">Bodylight.js </h1>
<h3 class="w3-center">open-source technology to bring simple to complex mathematical models (60 000 algebrodifferential equation) to web apps</h3>
<div style="margin:120px!important">
</div>
<h1 class="w3-center">to support free or commercial simulators </h1>
<h3 class="w3-center">e.g. in industry or medicine</h3>
<div style="margin:120px!important">
</div>
<div class="w3-center">
<div class="w3-card-4 w3-container w3-padding" style="width:820px;display: inline-block">
<h3 id="simulators" class="w3-center">see introductory presentation</h3>
<iframe frameBorder="0" width="800" height="600" style="border:0" src="https://orgpad.info/s/oqVL_-iyYxX?embed=true"></iframe>
<p class="w3-large">or open it in separated tab:<a href="https://orgpad.info/s/oqVL_-iyYxX" target="_blank">https://orgpad.info/s/oqVL_-iyYxX</a></p>
</div>
</div>
<div style="margin:120px!important">
</div>
<h3 class="w3-center" style="margin-top:20vh">with nice web simulators of cardiac hemodynamics:</h3>
<div class="w3-center">
<div class="w3-card-4 w3-container w3-padding" style="width:600px;display: inline-block">
<img width="530" height="210" src="img/hemomodelsim.gif" alt="Simulator of Hemodynamics" />
</div>
</div>
<div style="margin:120px!important">
</div>
<h3 class="w3-center">or simulator of iron metabolism</h3>
<div class="w3-center">
<div class="w3-card-4 w3-container w3-padding" style="width:600px;display: inline-block">
<img width="528" height="311" src="img/ironmetabolism.gif" alt="Simulator of Iron Metabolism" />
</div>
</div>
<div style="margin:120px!important">
</div>
<h3 class="w3-center">or simulator of respiratory diseases</h3>
<div class="w3-center">
<div class="w3-card-4 w3-container w3-padding" style="width:600px;display: inline-block">
<img width="576" height="304" src="img/bloodgases.gif" alt="Simulator of Blood Gases" />
</div>
</div>
<div style="margin:120px!important">
</div>
<h3 class="w3-center">and other (30+) topics and simulators to be constructed in near future see <a href="https://egolem.online">egolem.online</a></h3>
<div style="margin:120px!important">
</div>
<h3 class="w3-center">Visualisation is driven by real scientific model.</h3>
<div class="w3-center">
<div class="w3-container w3-padding" style="width:600px;display: inline-block">
<img width="371" height="241" src="img/heartanimation.gif" alt="Heart valves animation" />
</div>
</div>
<div style="margin:120px!important">
</div>
<h3 class="w3-center">Complex problems explained in game-like scenarios.</h3>
<div class="w3-center">
<div class="w3-container w3-padding" style="width:600px;display: inline-block">
<img width="377" height="280" src="img/hepcidineanim.gif" alt="Hepcidine Animation" />
</div>
</div>
<div style="margin:120px!important">
</div>
<h3 class="w3-center">Comprehend physiology, pathophysiology and clinical physiology.</h3>
<div class="w3-center">
<div class="w3-container w3-padding" style="width:600px;display: inline-block">
<img width="401" height="308" src="img/cardiacoutputeffect.gif" alt="Hepcidine Animation" />
</div>
</div>
<div style="margin:120px!important">
</div>
<h3 class="w3-center">Powered by Bodylight.js<sup>open-source</sup> technology with true in-browser experience. </h3>
<h4 class="w3-center">No server, no plugin, no addons needed.</h4>
<div class="w3-center">
<a href="bodylight.html">
<div class="w3-container w3-padding" style="width:600px;display: inline-block">
<img style="width:30%" src="img/bodylight_logo.svg" alt="Bodylight" />
</div>
</a>
</div>
<div style="margin:120px!important">
</div>
<h2 class="w3-center">Potential usage:</h2>
<h3 class="w3-center">Simulators in web-books e/learning material.</h3>
<div class="w3-center">
<div class="w3-card-4 w3-padding" style="width:875px;display: inline-block">
<img width="853" height="362" src="img/webapp.gif" alt="Webapp" />
</div>
</div>
<div style="margin:120px!important">
</div>
<h3 class="w3-center">Simulators as native apps for iOS or Android.</h3>
<div class="w3-center">
<div class="w3-card-4 w3-padding" style="width:435px;display: inline-block">
<img width="410" height="913" src="img/AndroidApp.gif" alt="Bodylight" />
</div>
</div>
<div style="margin:120px!important">
</div>
<h3 class="w3-center">Simulators in application with 3D graphics or in virtual reality.</h3>
<div class="w3-center">
<div class="w3-card-4 w3-container w3-padding" style="width:700px;display: inline-block">
<img width="600" src="img/virtualpatient.gif" alt="Simulator in VR" />
</div>
</div>
<div style="margin:120px!important">
</div>
<h3 class="w3-center">Simulators driving hardware mannequin and mockup of devices.</h3>
<h4 class="w3-center">(giving pathophysiology insights of virtual patient)</h4>
<div class="w3-center">
<div class="w3-card-4 w3-container w3-padding" style="width:700px;display: inline-block">
<img width="600" src="img/mannequin.jpg" alt="Mannequin" />
<br/>
<i>demo HW mannequin and unique mockup of ECMO devices made by Innomech s.r.o. in Czechia</i>
</div>
</div>
<div style="margin:120px!important">
</div>
<h3 class="w3-center">Bringing better understanding of complex problems in medicine and biology.</h3>
<div class="w3-center">
<div class="w3-card-4 w3-padding" style="width:435px;display: inline-block">
<h4>For students of medicine, physicians, clinical specialist, healthcare staff to learn and improve confidence in complex medicine.</h4>
<h4>For hospital department, simulation centers, healthcare industry to train their students, staff.</h4>
<h4>For patients and public to understand their condition and disease better.</h4>
</div>
</div>
<div style="margin:120px!important">
</div>
<h3 class="w3-center">powered by these standards and technologies:</h3>
<div class="w3-center w3-row-padding">
<div class="w3-quarter">
<div class="w3-card-2 w3-container w3-padding">
<img style="width:50%" src="img/web_components_logo.png" alt="Web Components" />
<h3 class="w3-center">Web Components standard</h3>
Design web simulator in HTML or Markdown with web components delivered by Bodylight.js library.
</div>
</div>
<div class="w3-quarter">
<div class="w3-card-2 w3-container w3-padding" style="height: 300px">
<img style="width:100%" src="img/modelica_logo.svg" alt="Modelica" />
Write models using Modelica language.
</div>
</div>
<div class="w3-quarter">
<div class="w3-card-2 w3-container w3-padding" style="height: 300px">
<img style="width:100%" src="img/web-assembly-logo.svg" alt="WebAssembly" />
<br/>
<br/>
Compile models to WebAssembly bringing near native speed of model simulation in browsers.
</div>
</div>
<div class="w3-quarter">
<div class="w3-card-2 w3-container w3-padding" style="height: 300px">
<img style="width:100%" src="img/createjs-logo.png" alt="Create.js" />
<br/>
<br/>
Animation designed in Adobe® Animate and exported as Create.js components
</div>
</div>
</div>
<div style="margin:120px!important">
</div>
<h3 id="simulators" class="w3-center">Prototype and tools</h3>
<div class="w3-center w3-padding">
<span class="w3-large">Simulators:</span>
<a href="/Bodylight-Scenarios/demo/" class="w3-button w3-border" title="Demo using Bodylight.js 1.0 and 2.0">DEMO</a>
<a href="/Bodylight-Scenarios/" class="w3-button w3-border" title="Selected education scenarios using simulators of human physiology using Bodylight.js 2.0">Scenarios</a>
<a href="https://www.physiome.cz/en/apps/" title="Educational simulators using older Bodylight.js 1.0" class="w3-button w3-border">Physiome Apps<sup>1.0</sup></a>
<a href="http://www.physiome.cz/apps/pvloops/" title="PV loops diagram in Bodylight.js 1.0" class="w3-button w3-border">PV loops<sup>1.0</sup></a>
<a href="/Bodylight-VirtualBody/" title="demo of 3d virtualbody and some simulators" class="w3-button w3-border">VirtualBody<sup>WebGL</sup></a>
<a href="/VR/breathing/" title="demo of 3D virtualbody with live animation using VR/AR capabilities" class="w3-button w3-border">Virtual Reality - breathing<sup>WebXR</sup></a>
</div>
<div class="w3-center w3-padding">
<span class="w3-large">Selected topics of human physiology with simulators:</span>
<a href="/Bodylight-Scenarios/hemodynamics/" class="w3-button w3-border">Hemodynamics <br/><span class="w3-tiny">(CZ only)</span></a>
<a href="/Bodylight-Scenarios/ironmetabolism/" class="w3-button w3-border">Iron Metabolism <br/><span class="w3-tiny">(CZ only)</span></a>
<a href="/Bodylight-Scenarios/bloodgases/" class="w3-button w3-border">Blood Gases <br/>Physiolibrary v3.0<span class="w3-tiny">(CZ only)</span></a>
<br/>
<a href="/Bodylight-Scenarios/bloodgases-p1/" class="w3-button w3-border">Blood Gases <br/>new - pure Modelica <span class="w3-tiny"></span></a>
<a href="/Bodylight-Scenarios/pharmakin/" class="w3-button w3-border">Pharmacokinetic and pharmacodynamic<br/>model demo<span class="w3-tiny">Bodylight v1.0</span></a>
</div>
</div>
<div style="margin:60px!important">
</div>
<div class="w3-center w3-padding">
<span class="w3-large">Docs:</span>
<a href="/Bodylight-docs/reference/" class="w3-button w3-border">Documentation - Reference Guide</a>
<a href="/Bodylight-docs/reference/#../tutorial/index.md" class="w3-button w3-border">Tutorial</a>
<span class="w3-large">Tools:</span>
<a href="/Bodylight-Editor/" class="w3-button w3-border">Editor</a>
<a href="/composer/" title="bodylight composer for older version 1.0" class="w3-button w3-border">Composer<sup>1.0</sup></a>
</div>
<div style="margin:120px!important">
</div>
<h3 class="w3-center">Contact us at:</h3>
<h4 class="w3-center">[email protected]</h4>
<div style="margin:120px!important">
</div>
<h3 class="w3-center">References:</h3>
<div class="w3-border w3-container w3-margin w3-padding">
<div class="w3-small">
<p>[1] Kofránek J., Rusz J.: Restoration of Guyton's diagram for regulation of the circulation as a basis for quantitative physiological model development. Physiological Research 59,897-908,2010 <a href="http://www.biomed.cas.cz/physiolres/pdf/59/59_897.pdf">PDF</a></p>
<p>[2] Mateják M.: Mateják, M. (2015) Formalization of Integrative Physiology. Dissertation, Charles University in Prague. <a href="https://www.physiomodel.org">www.physiomodel.org</a></p>
<p>[3] Mateják M., Kulhánek T., Šilar J., Privitzer P., Ježek F., Kofránek J.: Physiolibrary - Modelica library for Physiology, In Conference Proceeding, 10th International Modelica Conference, March 12, 2014, Lund, Sweden, (DOI:10.3384/ECP14096499)<a href="https://www.physiolibrary.org">www.physiolibrary.org</a></p>
<p>[4] Kulhánek T., Kofránek J.: Bodylight.js 2.0, In-browser web simulators using standard web components, OpenModelica/Modprod 2022 workshop
<a href="https://filedn.com/lHGc7w3H4jOpIe46u1nPt57/papers/Kulhanek-ModprodWorkshop2022-Bodylight.pptx">PPTX presentation (80 MB with animation)</a>
</p>
<p>[5] Šilar J, Polák D, Mládek A, Ježek F, Kurtz T, DiCarlo S, Živný J, Kofranek J
Development of In-Browser Simulators for Medical Education: Introduction of a Novel Software Toolchain
J Med Internet Res 2019;21(7):e14160
URL: <a href="https://www.jmir.org/2019/7/e14160">www.jmir.org/2019/7/e14160</a>
DOI: 10.2196/14160 </p>
<p>[6] Previous version of Bodylight.js framework. <a href="https://bodylight.physiome.cz/index1.0.html">
Bodylight.js 1.0
</a></p>
<p>[7] Bodylight.js 2.0 library: <a href="https://doi.org/10.5281/zenodo.4575354"><img src="https://zenodo.org/badge/doi/10.5281/zenodo.4575354.svg" alt="zenodo badge" /></a></p>
</div>
</div>
<div style="margin:60px!important">
</div>
<footer class="w3-bar" style="background:#4a4a4a; color:white;position:relative;z-index:1">
<section class="w3-center">2021 @ Creative Connections, Com-Sys TRADE, First Faculty of Medicine - Charles University - Prague</section></footer>
</body>
</html>