diff --git a/grayskull/strategy/pypi.py b/grayskull/strategy/pypi.py
index 20892a07b..94b47bc67 100644
--- a/grayskull/strategy/pypi.py
+++ b/grayskull/strategy/pypi.py
@@ -2,6 +2,7 @@
 import logging
 import os
 import re
+from collections.abc import Mapping
 from pathlib import Path
 from tempfile import mkdtemp
 from typing import Dict, Iterable, List, Optional
@@ -480,12 +481,25 @@ def get_metadata(recipe, config) -> dict:
         }
 
 
+def remove_all_inner_nones(metadata: Dict) -> Dict:
+    """Remove all inner None values from a dictionary."""
+    if not isinstance(metadata, Mapping):
+        return metadata
+    for k, v in metadata.items():
+        if not isinstance(v, list):
+            continue
+        metadata[k] = [i for i in v if i is not None]
+    return metadata
+
+
 def update_recipe(recipe: Recipe, config: Configuration, all_sections: List[str]):
     """Update one specific section."""
     from souschef.section import Section
 
     metadata = get_metadata(recipe, config)
+
     for section in all_sections:
+        metadata[section] = remove_all_inner_nones(metadata.get(section, {}))
         if metadata.get(section):
             if section == "package":
                 package_metadata = dict(metadata[section])
diff --git a/tests/test_pypi.py b/tests/test_pypi.py
index e05ad7e58..b1e9bae93 100644
--- a/tests/test_pypi.py
+++ b/tests/test_pypi.py
@@ -41,8 +41,10 @@
     get_url_filename,
     merge_pypi_sdist_metadata,
     normalize_requirements_list,
+    remove_all_inner_nones,
     remove_selectors_pkgs_if_needed,
     sort_reqs,
+    update_recipe,
 )
 from grayskull.utils import PyVer, format_dependencies, generate_recipe
 
@@ -1326,3 +1328,31 @@ def test_sort_reqs():
 
     assert sort_reqs(original_deps) in [sorted_deps_orig, sorted_deps_alpha]
     assert sort_reqs(original_deps_38) in [sorted_deps_orig_38, sorted_deps_alpha_38]
+
+
+@patch("grayskull.strategy.pypi.get_metadata")
+def test_metadata_pypi_none_value(mock_get_data):
+    mock_get_data.return_value = {
+        "package": {"name": "pypylon", "version": "1.2.3"},
+        "build": {"test": [None]},
+    }
+    recipe = Recipe(name="pypylon")
+    update_recipe(
+        recipe,
+        Configuration(name="pypylon", repo_github="https://github.com/basler/pypylon"),
+        ("package", "build"),
+    )
+    assert recipe["build"]["test"] == []
+
+
+@pytest.mark.parametrize(
+    "param, result",
+    [
+        ({"test": [None, None, None]}, {"test": []}),
+        ({"test": [None, "foo", None]}, {"test": ["foo"]}),
+        ({"test": [None, "foo", None, "bar", None]}, {"test": ["foo", "bar"]}),
+        ({"test": [None, "foo", None, "bar", None, None]}, {"test": ["foo", "bar"]}),
+    ],
+)
+def test_remove_all_inner_none(param, result):
+    assert remove_all_inner_nones(param) == result