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v0.2.1: Avoid normalization as part of ensemble process, which can ca…
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…use issues with some inputs (Fixes #21). Instead rely on upstream normalization
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chapmanb committed Jan 3, 2015
1 parent a012403 commit bdf24c6
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5 changes: 5 additions & 0 deletions HISTORY.md
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## 0.2.1 (3 January 2015)

- Do not normalize by default as part of ensemble combining. Prefer that to be
done upstream by other software.

## 0.2.0 (17 December 2014)

- Avoid putting fully specified indels into structural variant comparison, which
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8 changes: 4 additions & 4 deletions README.md
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Expand Up @@ -33,7 +33,7 @@ associated with different variant representations.

### Download

The latest release is 0.1.9 (6 November 2014): [bcbio.variation-0.1.9-standalone.jar][dl].
The latest release is 0.2.1 (3 January 2015): [bcbio.variation-0.2.1-standalone.jar][dl].
Run from the command line:

$ java -jar bcbio.variation-VERSION-standalone.jar [arguments]
Expand All @@ -44,7 +44,7 @@ the library for variant comparison, normalization and ensemble calling. Note
that bcbio.variation requires Java 1.7 since the underlying GATK libraries are
not compatible with earlier versions.

[dl]: https://github.com/chapmanb/bcbio.variation/releases/download/v0.1.9/bcbio.variation-0.1.9-standalone.jar
[dl]: https://github.com/chapmanb/bcbio.variation/releases/download/v0.2.1/bcbio.variation-0.2.1-standalone.jar

### As a library

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### Run GATK walker for variant statistics

$ lein uberjar
$ java -jar target/bcbio.variation-0.0.1-SNAPSHOT-standalone.jar -T VcfSimpleStatsWalker
$ java -jar target/bcbio.variation-RELEASE-standalone.jar -T VcfSimpleStatsWalker
-R test/data/GRCh37.fa --variant test/data/gatk-calls.vcf --out test.png

### Run custom GATK annotator

$ lein uberjar
$ java -jar target/bcbio.variation-0.0.1-SNAPSHOT-standalone.jar -T VariantAnnotator
$ java -jar target/bcbio.variation-RELEASE-standalone.jar -T VariantAnnotator
-A MeanNeighboringBaseQuality -R test/data/GRCh37.fa -I test/data/aligned-reads.bam
--variant test/data/gatk-calls.vcf -o annotated-file.vcf

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2 changes: 1 addition & 1 deletion project.clj
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(defproject bcbio.variation "0.2.0"
(defproject bcbio.variation "0.2.1"
:description "Toolkit to analyze genomic variation data, built on the GATK with Clojure"
:license {:name "MIT" :url "http://www.opensource.org/licenses/mit-license.html"}
:dependencies [[org.clojure/clojure "1.5.1"]
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2 changes: 1 addition & 1 deletion src/bcbio/variation/ensemble.clj
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(or (get (vec (:names config)) i)
(str "v" i)))
:file vrn-file
:normalize true}
:normalize false}
(->/when (get config :prep-inputs true)
(merge {:preclean true :prep true}))))

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