diff --git a/cmd/cartesi-rollups-cli/root/app/app.go b/cmd/cartesi-rollups-cli/root/app/app.go
index 2096fce44..71b0f376c 100644
--- a/cmd/cartesi-rollups-cli/root/app/app.go
+++ b/cmd/cartesi-rollups-cli/root/app/app.go
@@ -7,6 +7,7 @@ import (
 	"github.com/cartesi/rollups-node/cmd/cartesi-rollups-cli/root/app/deploy"
 	"github.com/cartesi/rollups-node/cmd/cartesi-rollups-cli/root/app/list"
 	"github.com/cartesi/rollups-node/cmd/cartesi-rollups-cli/root/app/register"
+	"github.com/cartesi/rollups-node/cmd/cartesi-rollups-cli/root/app/status"
 	"github.com/cartesi/rollups-node/cmd/cartesi-rollups-cli/root/common"
 	"github.com/spf13/cobra"
 )
@@ -30,4 +31,5 @@ func init() {
 	Cmd.AddCommand(register.Cmd)
 	Cmd.AddCommand(deploy.Cmd)
 	Cmd.AddCommand(list.Cmd)
+	Cmd.AddCommand(status.Cmd)
 }
diff --git a/cmd/cartesi-rollups-cli/root/app/status/status.go b/cmd/cartesi-rollups-cli/root/app/status/status.go
new file mode 100644
index 000000000..78e484e03
--- /dev/null
+++ b/cmd/cartesi-rollups-cli/root/app/status/status.go
@@ -0,0 +1,89 @@
+// (c) Cartesi and individual authors (see AUTHORS)
+// SPDX-License-Identifier: Apache-2.0 (see LICENSE)
+
+package status
+
+import (
+	"fmt"
+	"os"
+
+	cmdcommon "github.com/cartesi/rollups-node/cmd/cartesi-rollups-cli/root/common"
+	"github.com/cartesi/rollups-node/internal/model"
+	"github.com/ethereum/go-ethereum/common"
+	"github.com/spf13/cobra"
+)
+
+var Cmd = &cobra.Command{
+	Use:     "status",
+	Short:   "Display and set application status",
+	Example: examples,
+	Run:     run,
+}
+
+const examples = `# Get application status:
+cartesi-rollups-cli app status -a 0x000000000000000000000000000000000`
+
+var (
+	enable  bool
+	disable bool
+)
+
+func init() {
+	Cmd.Flags().StringVarP(
+		&cmdcommon.ApplicationAddress,
+		"address",
+		"a",
+		"",
+		"Application contract address",
+	)
+	cobra.CheckErr(Cmd.MarkFlagRequired("address"))
+
+	Cmd.Flags().BoolVarP(
+		&enable,
+		"enable",
+		"e",
+		false,
+		"Enable the application",
+	)
+
+	Cmd.Flags().BoolVarP(
+		&disable,
+		"disable",
+		"d",
+		false,
+		"Disable the application",
+	)
+
+}
+
+func run(cmd *cobra.Command, args []string) {
+	ctx := cmd.Context()
+
+	if cmdcommon.Database == nil {
+		panic("Database was not initialized")
+	}
+
+	address := common.HexToAddress(cmdcommon.ApplicationAddress)
+	application, err := cmdcommon.Database.GetApplication(ctx, address)
+	cobra.CheckErr(err)
+
+	if (!cmd.Flags().Changed("enable")) && (!cmd.Flags().Changed("disable")) {
+		fmt.Println(application.Status)
+		os.Exit(0)
+	}
+
+	if cmd.Flags().Changed("enable") && cmd.Flags().Changed("disable") {
+		fmt.Fprintln(os.Stderr, "Cannot enable and disable at the same time")
+		os.Exit(1)
+	}
+
+	status := model.ApplicationStatusRunning
+	if cmd.Flags().Changed("disable") {
+		status = model.ApplicationStatusNotRunning
+	}
+
+	err = cmdcommon.Database.UpdateApplicationStatus(ctx, address, status)
+	cobra.CheckErr(err)
+
+	fmt.Printf("Application status updated to %s\n", status)
+}
diff --git a/internal/advancer/advancer.go b/internal/advancer/advancer.go
index 3f660df7d..fa3213705 100644
--- a/internal/advancer/advancer.go
+++ b/internal/advancer/advancer.go
@@ -50,6 +50,12 @@ func (advancer *Advancer) Poller(pollingInterval time.Duration) (*poller.Poller,
 // runs them through the cartesi machine,
 // and updates the repository with the outputs.
 func (advancer *Advancer) Step(ctx context.Context) error {
+	// Dynamically updates the list of machines
+	err := advancer.machines.UpdateMachines(ctx)
+	if err != nil {
+		return err
+	}
+
 	apps := advancer.machines.Apps()
 
 	// Gets the unprocessed inputs (of all apps) from the repository.
@@ -125,6 +131,7 @@ type Repository interface {
 
 type Machines interface {
 	GetAdvanceMachine(app Address) (machines.AdvanceMachine, bool)
+	UpdateMachines(ctx context.Context) error
 	Apps() []Address
 }
 
diff --git a/internal/advancer/advancer_test.go b/internal/advancer/advancer_test.go
index 847af8405..f86433264 100644
--- a/internal/advancer/advancer_test.go
+++ b/internal/advancer/advancer_test.go
@@ -226,6 +226,10 @@ func (mock *MachinesMock) GetAdvanceMachine(app Address) (machines.AdvanceMachin
 	return machine, exists
 }
 
+func (m *MachinesMock) UpdateMachines(ctx context.Context) error {
+	return nil // FIXME
+}
+
 func (mock *MachinesMock) Apps() []Address {
 	return []Address{}
 }
diff --git a/internal/advancer/machines/machines.go b/internal/advancer/machines/machines.go
index cd9c95bd6..97eafedb5 100644
--- a/internal/advancer/machines/machines.go
+++ b/internal/advancer/machines/machines.go
@@ -41,8 +41,10 @@ type InspectMachine interface {
 // Machines is a thread-safe type that manages the pool of cartesi machines being used by the node.
 // It contains a map of applications to machines.
 type Machines struct {
-	mutex    sync.RWMutex
-	machines map[Address]*nm.NodeMachine
+	mutex      sync.RWMutex
+	machines   map[Address]*nm.NodeMachine
+	repository Repository
+	verbosity  cm.ServerVerbosity
 }
 
 // Load initializes the cartesi machines.
@@ -79,7 +81,39 @@ func Load(ctx context.Context, repo Repository, verbosity cm.ServerVerbosity) (*
 		machines[config.AppAddress] = machine
 	}
 
-	return &Machines{machines: machines}, errs
+	return &Machines{machines: machines, repository: repo, verbosity: verbosity}, errs
+}
+
+func (m *Machines) UpdateMachines(ctx context.Context) error {
+	configs, err := m.repository.GetMachineConfigurations(ctx)
+	if err != nil {
+		return err
+	}
+
+	for _, config := range configs {
+		if m.Exists(config.AppAddress) {
+			continue
+		}
+
+		machine, err := createMachine(ctx, m.verbosity, config)
+		if err != nil {
+			slog.Error("advancer: Failed to create machine", "app", config.AppAddress, "error", err)
+			continue
+		}
+
+		err = catchUp(ctx, m.repository, config.AppAddress, machine, config.ProcessedInputs)
+		if err != nil {
+			slog.Error("Failed to sync the machine", "app", config.AppAddress, "error", err)
+			machine.Close()
+			continue
+		}
+
+		m.Add(config.AppAddress, machine)
+	}
+
+	m.RemoveAbsent(configs)
+
+	return nil
 }
 
 // GetAdvanceMachine gets the machine associated with the application from the map.
@@ -107,6 +141,30 @@ func (m *Machines) Add(app Address, machine *nm.NodeMachine) bool {
 	}
 }
 
+func (m *Machines) Exists(app Address) bool {
+	m.mutex.Lock()
+	defer m.mutex.Unlock()
+
+	_, exists := m.machines[app]
+	return exists
+}
+
+func (m *Machines) RemoveAbsent(configs []*MachineConfig) {
+	m.mutex.Lock()
+	defer m.mutex.Unlock()
+	configMap := make(map[Address]bool)
+	for _, config := range configs {
+		configMap[config.AppAddress] = true
+	}
+	for address, machine := range m.machines {
+		if !configMap[address] {
+			slog.Info("advancer: Application was disabled, shutting down machine", "application", address)
+			machine.Close()
+			delete(m.machines, address)
+		}
+	}
+}
+
 // Delete deletes an application from the map.
 // It returns the associated machine, if any.
 func (m *Machines) Delete(app Address) *nm.NodeMachine {
@@ -179,7 +237,7 @@ func createMachine(ctx context.Context,
 		return nil, err
 	}
 
-	slog.Debug("advancer: loading machine on server", "application", config.AppAddress,
+	slog.Info("advancer: loading machine on server", "application", config.AppAddress,
 		"remote-machine", address, "template-path", config.SnapshotPath)
 	// Creates a CartesiMachine from the snapshot.
 	runtimeConfig := &emulator.MachineRuntimeConfig{}
diff --git a/internal/evmreader/evmreader.go b/internal/evmreader/evmreader.go
index 5e5068503..5d3d633ea 100644
--- a/internal/evmreader/evmreader.go
+++ b/internal/evmreader/evmreader.go
@@ -114,6 +114,7 @@ type EvmReader struct {
 	inputBoxDeploymentBlock uint64
 	defaultBlock            DefaultBlock
 	epochLengthCache        map[Address]uint64
+	hasEnabledApps          bool
 }
 
 func (r *EvmReader) String() string {
@@ -138,6 +139,7 @@ func NewEvmReader(
 		inputBoxDeploymentBlock: inputBoxDeploymentBlock,
 		defaultBlock:            defaultBlock,
 		contractFactory:         contractFactory,
+		hasEnabledApps:          true,
 	}
 }
 
@@ -181,6 +183,7 @@ func (r *EvmReader) watchForNewBlocks(ctx context.Context, ready chan<- struct{}
 			// Every time a new block arrives
 			slog.Debug("evmreader: New block header received", "blockNumber", header.Number, "blockHash", header.Hash())
 
+			slog.Debug("evmreader: Retrieving enabled applications")
 			// Get All Applications
 			runningApps, err := r.repository.GetAllRunningApplications(ctx)
 			if err != nil {
@@ -191,6 +194,18 @@ func (r *EvmReader) watchForNewBlocks(ctx context.Context, ready chan<- struct{}
 				continue
 			}
 
+			if len(runningApps) == 0 {
+				if r.hasEnabledApps {
+					slog.Info("evmreader: No registered applications enabled")
+				}
+				r.hasEnabledApps = false
+				continue
+			}
+			if !r.hasEnabledApps {
+				slog.Info("evmreader: Found enabled applications")
+			}
+			r.hasEnabledApps = true
+
 			// Build Contracts
 			var apps []application
 			for _, app := range runningApps {
diff --git a/internal/repository/base.go b/internal/repository/base.go
index 7d97a6432..b9106669a 100644
--- a/internal/repository/base.go
+++ b/internal/repository/base.go
@@ -493,6 +493,39 @@ func (pg *Database) GetApplication(
 	return &app, nil
 }
 
+func (pg *Database) UpdateApplicationStatus(
+	ctx context.Context,
+	appAddressKey Address,
+	newStatus ApplicationStatus,
+) error {
+	query := `
+	UPDATE
+		application
+	SET
+		status = @newStatus
+	WHERE
+		contract_address = @contractAddress`
+
+	args := pgx.NamedArgs{
+		"contractAddress": appAddressKey,
+		"newStatus":       newStatus,
+	}
+
+	commandTag, err := pg.db.Exec(ctx, query, args)
+	if err != nil {
+		return fmt.Errorf("UpdateApplicationStatus Exec failed: %w", err)
+	}
+
+	if commandTag.RowsAffected() == 0 {
+		slog.Debug("UpdateApplicationStatus affected no rows",
+			"service", "repository",
+			"app", appAddressKey)
+		return fmt.Errorf("no application found with contract address: %s", appAddressKey)
+	}
+
+	return nil
+}
+
 func (pg *Database) GetEpochs(ctx context.Context, application Address) ([]Epoch, error) {
 	query := `
 	SELECT