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Start working with LOINC terminology in Aidbox

Load LOINC into Aidbox

LOINC, or Logical Observation Identifiers Names and Codes, is an extensive medical terminology system that can be incorporated into FHIR ValueSet resources. It is a universal standard for identifying health measurements, observations, and documents, which helps facilitate the sharing and aggregation of clinical results.

We provide out-of-the box integration with LOINC through Aidbox Configuration Project.

How to set up Aidbox with LOINC terminology

To correctly set up Aidbox, we'll utilize the Aidbox configuration projects.

There's an existing guide for this process. Adhere to this guide, but note a variation when you reach the Configure the Aidbox step: instead of using the recommended configuration projects (R4,R4B,R5,etc.) — clone this specific project: 

git clone \
  https://github.com/Aidbox/aidbox-project-template-loinc.git \
  aidbox-project && \
  cd aidbox-project && \
  rm -rf .git

This project is tailored with specific configurations essential for terminology loading.

Configuration Overview: Key Features and Distinctions

If you already have a configuration project, you can replicate these steps to enable LOINC terminology in your Aidbox instance.

Added LOINC dependency to configuration project

{% code title="zen-package.edn" %}

{:deps {loinc "[email protected]:zen-fhir/loinc.git"}}

{% endcode %}

By adding this dependency, we instruct Aidbox to load the zen.fhir ValueSet definition, which is meant to include all codes from LOINC. This ValueSet definition contains a specific directive detailing the FTR manifest. Aidbox'll use this manifest to input the actual RxNorm concepts into the database.

{% code title="loinc/zrc/loinc.edn" lineNumbers="true" %}

{ns loinc,
 import #{zen.fhir},
 value-set
 {:zen/tags #{zen.fhir/value-set},
  :zen/desc "Includes all concepts from LOINC.",
  :zen.fhir/version "0.6.0",
  :fhir/code-systems
  #{{:fhir/url "http://loinc.org", :zen.fhir/content :bundled}},
  :uri "http://loinc.org/vs",
  :version "2.76",
  :ftr
  {:module "loinc",
   :source-url "https://storage.googleapis.com",
   :ftr-path "ftr",
   :source-type :cloud-storage,
   :tag "prod"}}}

{% endcode %}

Imported LOINC namespace to configuration project entrypoint

{ns main
 import #{aidbox
          config
          loinc}
 …}

Zen requires importing a namespace into the entrypoint to load the ValueSet definition into the definitions store.

FTR Pull Feature — instruct Aidbox to load concepts into the database

By default, Aidbox does not load terminologies into the database as that can take a lot of disk space. This means that full terminology functionality won’t be available until you enable it manually. When you set it to true, Aidbox will load terminologies into the database on the next startup and start functioning as a fully-featured terminology server.

To achieve that we set ftr.pull.enable to true in features map.

{% hint style="info" %} When adding this feature to existing configuration projects, be mindful. If you include dependencies like hl7-fhir-r4-core or hl7-fhir-us-core, Aidbox will load terminologies from these packages, which are sizable. Therefore, loading all the concepts into the database might take a while. {% endhint %}

{% code title="zrc/config.edn" %}

 features
 {:zen/tags #{aidbox.config/features}
  :ftr {:pull {:enable true}}}

{% endcode %}

What else you can do with configs related to terminology?

Lock Aidbox's start until all concepts are stored in the database

When ftr.pull.enable is set to true, Aidbox loads concepts asynchronously by default. This means that immediately after starting, there might be no concepts available because they are still loading. To address this behavior, set ftr.pull.sync to true.

{% code title="zrc/config.edn" %}

 features
 {:zen/tags #{aidbox.config/features}
  :ftr {:pull {:enable true
               :sync true}}}

{% endcode %}

How can you determine if the concepts are still loading or have already loaded? (Usable for async pulls)

Access the Aidbox UI and navigate to Database > Running Queries. Look for a query that includes "_import"; this query is responsible for loading concepts into your database. Once this query disappears from the list, you can check the concepts in the database. Proceed to Database > DB Console and enter the following query:

SELECT count(*) from concept where resource->>'system' = 'http://loinc.org'

Terminology translations

Currently, we support various LOINC terminology translations, and we can incorporate additional translation variants as needed. Translations are stored in the concept .designation property, and when a package includes multiple languages, the original language is also retained within the .designation property. To select the desired translation, simply modify the link to the corresponding package in zen-package.edn.

Zen Package LinkLanguages (IETF BCP 47 tags)
[email protected]:zen-fhir/loinc.giten
[email protected]:zen-fhir/loinc-fr-ca.giten, fr-ca

See also $translate-concepts RPC.