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Myc-regulated alternative splicing events in aggressive prostate cancer

Scripts for plotting figures and running analysis throughout the manuscript

Folders or files of scripts are named following this format: 'figure index'.'plot/analysis name'

Notes

  1. Customized scripts are hard-coded for specific analysis or plots.
  2. For similar type of figure/analysis, only show one script as an example.
  3. Scatter plots of pathway-AS correlation are generated by PEGASAS pipeline(https://github.com/Xinglab/PEGASAS)
  4. Sashimi plots are generated by rmats2sashimiplot(https://github.com/Xinglab/rmats2sashimiplot)
  5. Generating PEGASAS input from rMATS output(custom procedure for the analysis in the paper)

Contact

Yang Pan [email protected] Yi Xing [email protected]

Citation

Phillips J.W.*, Pan Y.*, Tsai B.L., Xie Z., Demirdjian L., Xiao W., Yang H.T., Zhang Y., Lin C.H., Cheng D., Hu Q., Liu S., Black D.L., Witte O.N.+, Xing Y.+ (2020) Pathway-guided analysis identifies Myc-dependent alternative pre-mRNA splicing in aggressive prostate cancers. PNAS, 117(10):5269-79 (+ joint corresponding authors; * joint first authors)