diff --git a/tests/wamr-test-suites/spec-test-script/memory64.patch b/tests/wamr-test-suites/spec-test-script/memory64.patch
new file mode 100644
index 0000000000..739a1df60d
--- /dev/null
+++ b/tests/wamr-test-suites/spec-test-script/memory64.patch
@@ -0,0 +1,28 @@
+diff --git a/test/core/memory.wast b/test/core/memory.wast
+index 1dd5b84..497b69f 100644
+--- a/test/core/memory.wast
++++ b/test/core/memory.wast
+@@ -76,17 +76,17 @@
+   "memory size must be at most 65536 pages (4GiB)"
+ )
+ 
+-(assert_invalid
++(assert_malformed
+   (module quote "(memory 0x1_0000_0000)")
+-  "memory size must be at most 65536 pages (4GiB)"
++  "i32 constant out of range"
+ )
+-(assert_invalid
++(assert_malformed
+   (module quote "(memory 0x1_0000_0000 0x1_0000_0000)")
+-  "memory size must be at most 65536 pages (4GiB)"
++  "i32 constant out of range"
+ )
+-(assert_invalid
++(assert_malformed
+   (module quote "(memory 0 0x1_0000_0000)")
+-  "memory size must be at most 65536 pages (4GiB)"
++  "i32 constant out of range"
+ )
+ 
+ (module
diff --git a/tests/wamr-test-suites/test_wamr.sh b/tests/wamr-test-suites/test_wamr.sh
index 22422083e8..143cf86e0f 100755
--- a/tests/wamr-test-suites/test_wamr.sh
+++ b/tests/wamr-test-suites/test_wamr.sh
@@ -499,6 +499,7 @@ function spec_test()
         git reset --hard 48e69f394869c55b7bbe14ac963c09f4605490b6
         git checkout 044d0d2e77bdcbe891f7e0b9dd2ac01d56435f0b -- test/core/elem.wast
         git apply ../../spec-test-script/ignore_cases.patch
+        git apply ../../spec-test-script/memory64.patch
 
         echo "compile the reference intepreter"
         pushd interpreter