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Merge pull request #85 from SuLab/main
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github-actions[bot] authored Feb 9, 2023
2 parents 2496dc8 + 4baac26 commit 30c64b5
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Showing 3 changed files with 5 additions and 46 deletions.
4 changes: 2 additions & 2 deletions indication_paths.json
Original file line number Diff line number Diff line change
Expand Up @@ -424688,7 +424688,7 @@
"directed": true,
"graph": {
"_id": "DB01165_MESH_D013290_1",
"disease": null,
"disease": "Streptococcal Infections",
"disease_mesh": "MESH:D013290",
"drug": "ofloxacin",
"drug_mesh": "MESH:D015242",
Expand Down Expand Up @@ -424741,7 +424741,7 @@
{
"id": "MESH:D013290",
"label": "Disease",
"name": "Streptococcus pyogenes infection"
"name": "Streptococcal Infections"
}
],
"reference": [
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4 changes: 2 additions & 2 deletions indication_paths.yaml
Original file line number Diff line number Diff line change
Expand Up @@ -268039,7 +268039,7 @@
- directed: true
graph:
_id: DB01165_MESH_D013290_1
disease: null
disease: Streptococcal Infections
disease_mesh: MESH:D013290
drug: ofloxacin
drug_mesh: MESH:D015242
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name: Streptococcus pyogenes
- id: MESH:D013290
label: Disease
name: Streptococcus pyogenes infection
name: Streptococcal Infections
reference:
- https://en.wikipedia.org/wiki/Ofloxacin#Mode_of_action
- https://www.ebi.ac.uk/chembl/target_report_card/CHEMBL2311224/
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43 changes: 1 addition & 42 deletions submission.yaml
Original file line number Diff line number Diff line change
@@ -1,42 +1 @@
- directed: true
graph:
_id: DB01165_MESH_D013290_1
disease: Streptococcal Infections
disease_mesh: MESH:D013290
drug: ofloxacin
drug_mesh: MESH:D015242
drugbank: DB:DB01165
links:
- key: negatively regulates
source: MESH:D015242
target: InterPro:IPR013759
- key: positively regulates
source: InterPro:IPR013759
target: GO:0006265
- key: in taxon
source: GO:0006265
target: NCBITaxon:1314
- key: causes
source: NCBITaxon:1314
target: MESH:D013290
multigraph: true
nodes:
- id: MESH:D015242
label: Drug
name: ofloxacin
- id: InterPro:IPR013759
label: GeneFamily
name: DNA topoisomerase, type IIA, subunit B, C-terminal
- id: GO:0006265
label: BiologicalProcess
name: DNA topological change
- id: NCBITaxon:1314
label: OrganismTaxon
name: Streptococcus pyogenes
- id: MESH:D013290
label: Disease
name: Streptococcal Infections
reference:
- https://en.wikipedia.org/wiki/Ofloxacin#Mode_of_action
- https://www.ebi.ac.uk/chembl/target_report_card/CHEMBL2311224/
- https://go.drugbank.com/drugs/DB01165

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