diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 610222e..2832413 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -47,7 +47,7 @@ jobs:
       fail-fast: false # If one platform fails, allow the rest to keep testing.
       matrix:
         rust: [stable]
-        python-version: ["3.9", "3.10", "3.11", "3.12", "3.13", "pypy-3.9"]
+        python-version: ["3.9", "3.10", "3.11", "3.12", "3.13", "3.13t", "pypy-3.9", "pypy-3.10"]
         platform:
           [
             {
@@ -65,11 +65,6 @@ jobs:
               python-architecture: "x64",
               rust-target: "x86_64-pc-windows-msvc",
             },
-            {
-              os: "windows-latest",
-              python-architecture: "x86",
-              rust-target: "i686-pc-windows-msvc",
-            },
           ]
         exclude:
           # PyPy doesn't release 32-bit Windows builds any more
@@ -89,7 +84,7 @@ jobs:
 
           # Test the `nightly` feature
           - rust: nightly
-            python-version: "3.12"
+            python-version: "3.13"
             platform:
               {
                 os: "ubuntu-latest",
@@ -99,11 +94,16 @@ jobs:
             msrv: "nightly"
             extra_features: "nightly"
 
+          # Test 32-bit windows just on latest Python
+          - rust: stable
+            python-version: "3.13"
+            platform: { os: "windows-latest", python-architecture: "x86", rust-target: "i686-pc-windows-msvc" }
+
     steps:
       - uses: actions/checkout@v4
 
       - name: Set up Python ${{ matrix.python-version }}
-        uses: actions/setup-python@v5
+        uses: Quansight-Labs/setup-python@v5
         with:
           python-version: ${{ matrix.python-version }}
           architecture: ${{ matrix.platform.python-architecture }}
@@ -125,8 +125,8 @@ jobs:
       - name: Build
         run: cargo build --features=${{env.features}} --verbose --target ${{ matrix.platform.rust-target }}
 
-      # uvloop doesn't compile under Windows and PyPy
-      - if: ${{ matrix.platform.os != 'windows-latest' && !startsWith(matrix.python-version, 'pypy') }}
+      # uvloop doesn't compile under Windows and PyPy, nor for free-threaded Python
+      - if: ${{ matrix.platform.os != 'windows-latest' && !startsWith(matrix.python-version, 'pypy') && !endsWith(matrix.python-version, 't') }}
         name: Install pyo3-asyncio test dependencies
         run: |
           python -m pip install -U uvloop
diff --git a/pytests/test_async_std_uvloop.rs b/pytests/test_async_std_uvloop.rs
index 972cebd..10477fc 100644
--- a/pytests/test_async_std_uvloop.rs
+++ b/pytests/test_async_std_uvloop.rs
@@ -4,6 +4,14 @@ fn main() -> pyo3::PyResult<()> {
     pyo3::prepare_freethreaded_python();
 
     Python::with_gil(|py| {
+        // uvloop not supported on the free-threaded build yet
+        // https://github.com/MagicStack/uvloop/issues/642
+        let sysconfig = py.import("sysconfig")?;
+        let is_freethreaded = sysconfig.call_method1("get_config_var", ("Py_GIL_DISABLED",))?;
+        if is_freethreaded.is_truthy()? {
+            return Ok(());
+        }
+
         let uvloop = py.import("uvloop")?;
         uvloop.call_method0("install")?;
 
diff --git a/pytests/test_tokio_current_thread_uvloop.rs b/pytests/test_tokio_current_thread_uvloop.rs
index 2d1b47d..9ea8a4b 100644
--- a/pytests/test_tokio_current_thread_uvloop.rs
+++ b/pytests/test_tokio_current_thread_uvloop.rs
@@ -13,6 +13,14 @@ fn main() -> pyo3::PyResult<()> {
     });
 
     Python::with_gil(|py| {
+        // uvloop not supported on the free-threaded build yet
+        // https://github.com/MagicStack/uvloop/issues/642
+        let sysconfig = py.import("sysconfig")?;
+        let is_freethreaded = sysconfig.call_method1("get_config_var", ("Py_GIL_DISABLED",))?;
+        if is_freethreaded.is_truthy()? {
+            return Ok(());
+        }
+
         let uvloop = py.import("uvloop")?;
         uvloop.call_method0("install")?;
 
diff --git a/pytests/test_tokio_multi_thread_uvloop.rs b/pytests/test_tokio_multi_thread_uvloop.rs
index f664919..9921c09 100644
--- a/pytests/test_tokio_multi_thread_uvloop.rs
+++ b/pytests/test_tokio_multi_thread_uvloop.rs
@@ -5,6 +5,14 @@ fn main() -> pyo3::PyResult<()> {
     pyo3::prepare_freethreaded_python();
 
     Python::with_gil(|py| {
+        // uvloop not supported on the free-threaded build yet
+        // https://github.com/MagicStack/uvloop/issues/642
+        let sysconfig = py.import("sysconfig")?;
+        let is_freethreaded = sysconfig.call_method1("get_config_var", ("Py_GIL_DISABLED",))?;
+        if is_freethreaded.is_truthy()? {
+            return Ok(());
+        }
+
         let uvloop = py.import("uvloop")?;
         uvloop.call_method0("install")?;