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DESCRIPTION
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DESCRIPTION
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Package: ANCOMBC
Type: Package
Title: Microbiome differential abudance and correlation analyses with bias
correction
Version: 2.6.1
Description: ANCOMBC is a package containing differential abundance (DA) and
correlation analyses for microbiome data. Specifically, the package includes
Analysis of Compositions of Microbiomes with Bias Correction 2 (ANCOM-BC2),
Analysis of Compositions of Microbiomes with Bias Correction (ANCOM-BC), and
Analysis of Composition of Microbiomes (ANCOM) for DA analysis, and Sparse
Estimation of Correlations among Microbiomes (SECOM) for correlation
analysis. Microbiome data are typically subject to two sources of biases:
unequal sampling fractions (sample-specific biases) and differential
sequencing efficiencies (taxon-specific biases). Methodologies included in
the ANCOMBC package are designed to correct these biases and construct
statistically consistent estimators.
Date: 2024-10-20
Authors@R: c(
person(given = "Huang",
family = "Lin",
email = "[email protected]",
role = c("cre", "aut"),
comment = c(ORCID = "0000-0002-4892-7871")))
License: Artistic-2.0
Imports: stats,
CVXR, DescTools, Hmisc, MASS, Matrix, Rdpack, doParallel, doRNG, energy,
foreach, gtools, lme4, lmerTest, multcomp, nloptr, parallel, utils
Suggests: mia (>= 1.6.0),
DT, S4Vectors, SingleCellExperiment, SummarizedExperiment,
TreeSummarizedExperiment, dplyr, knitr, magrittr, microbiome,
phyloseq, rmarkdown, testthat, tidyr, tidyverse
biocViews:
DifferentialExpression,
Microbiome,
Normalization,
Sequencing,
Software
BugReports: https://github.com/FrederickHuangLin/ANCOMBC/issues
URL: https://github.com/FrederickHuangLin/ANCOMBC
VignetteBuilder: knitr
RdMacros: Rdpack
Encoding: UTF-8
RoxygenNote: 7.2.3
Depends:
R (>= 4.3.0)
LazyData: false