EVA-3571 New stats calculator (#196)

* Added new stats calculator

pom.xml

@@ -198,6 +198,7 @@
                 <filtering>true</filtering>
                 <includes>
                     <include>test-mongo.properties</include>
+                    <include>test-stats.properties</include>
                     <include>opencga/conf/storage-mongodb.properties</include>
                 </includes>
             </testResource>
@@ -208,6 +209,7 @@
                 <filtering>false</filtering>
                 <excludes>
                     <exclude>test-mongo.properties</exclude>
+                    <exclude>test-stats.properties</exclude>
                     <exclude>opencga/conf/storage-mongodb.properties</exclude>
                 </excludes>
             </testResource>

src/main/java/uk/ac/ebi/eva/commons/models/data/VariantStats.java

@@ -239,7 +239,7 @@ private Genotype normalizeGenotypeAlleles(Genotype g) {
         }
     }
 
-    void setGenotypesCount(Map<Genotype, Integer> genotypesCount) {
+    public void setGenotypesCount(Map<Genotype, Integer> genotypesCount) {
         this.genotypesCount = genotypesCount;
     }
 

src/main/java/uk/ac/ebi/eva/commons/models/mongo/entity/VariantDocument.java

@@ -266,4 +266,8 @@ public Set<VariantStatsMongo> getVariantStatsMongo() {
     public Set<VariantAnnotation> getAnnotations() {
         return annotations;
     }
+
+    public void setStats(Set<VariantStatsMongo> variantStats) {
+        this.variantStatsMongo = variantStats;
+    }
 }

src/main/java/uk/ac/ebi/eva/commons/models/mongo/entity/subdocuments/VariantSourceEntryMongo.java

@@ -174,4 +174,19 @@ private BasicDBObject buildAttributes(Map<String, String> attributes) {
         return attrs;
     }
 
+    public BasicDBObject getSampleData() {
+        return samp;
+    }
+
+    public String getStudyId() {
+        return studyId;
+    }
+
+    public String getFileId() {
+        return fileId;
+    }
+
+    public String[] getAlternates() {
+        return alternates;
+    }
 }

src/main/java/uk/ac/ebi/eva/pipeline/configuration/BeanNames.java

@@ -26,17 +26,20 @@ public class BeanNames {
     public static final String VARIANT_ANNOTATION_READER = "variant-annotation-reader";
     public static final String VARIANT_READER = "variant-reader";
     public static final String ACCESSION_REPORT_READER = "accession-report-reader";
+    public static final String VARIANT_STATS_READER = "variant-stats-reader";
 
     public static final String VEP_ANNOTATION_PROCESSOR = "vep-annotation-processor";
     public static final String ANNOTATION_PARSER_PROCESSOR = "annotation-parser-processor";
     public static final String ANNOTATION_COMPOSITE_PROCESSOR = "annotation-composite-processor";
+    public static final String VARIANT_STATS_PROCESSOR = "variant-stats-processor";
 
     public static final String GENE_WRITER = "gene-writer";
     public static final String ANNOTATION_WRITER = "annotation-writer";
     public static final String ANNOTATION_IN_VARIANT_WRITER = "annotation-in-variant-writer";
     public static final String COMPOSITE_ANNOTATION_VARIANT_WRITER = "composite-annotation-variant-writer";
     public static final String VARIANT_WRITER = "variant-writer";
     public static final String ACCESSION_IMPORTER = "accession-importer";
+    public static final String VARIANT_STATS_WRITER = "variant-stats-writer";
 
     public static final String ANNOTATION_SKIP_STEP_DECIDER = "annotation-skip-step-decider";
     public static final String STATISTICS_SKIP_STEP_DECIDER = "statistics-skip-step-decider";
@@ -60,6 +63,7 @@ public class BeanNames {
     public static final String DROP_FILES_BY_STUDY_STEP = "drop-files-by-study-step";
     public static final String LOAD_ANNOTATION_METADATA_STEP = "annotation-metadata-step";
     public static final String ACCESSION_IMPORT_STEP = "accession-import-step";
+    public static final String CALCULATE_AND_LOAD_STATISTICS_STEP = "calculate-load-statistics-step";
 
     public static final String AGGREGATED_VCF_JOB = "aggregated-vcf-job";
     public static final String ANNOTATE_VARIANTS_JOB = "annotate-variants-job";
@@ -69,4 +73,5 @@ public class BeanNames {
     public static final String CALCULATE_STATISTICS_JOB = "calculate-statistics-job";
     public static final String DROP_STUDY_JOB = "drop-study-job";
     public static final String ACCESSION_IMPORT_JOB = "accession-import-job";
+    public static final String CALCULATE_AND_LOAD_STATISTICS_JOB = "calculate-load-statistics-job";
 }

src/main/java/uk/ac/ebi/eva/pipeline/configuration/io/readers/VariantStatsReaderConfiguration.java

@@ -0,0 +1,43 @@
+/*
+ * Copyright 2024 EMBL - European Bioinformatics Institute
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *      http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+package uk.ac.ebi.eva.pipeline.configuration.io.readers;
+
+import org.springframework.batch.core.configuration.annotation.StepScope;
+import org.springframework.batch.item.ItemStreamReader;
+import org.springframework.context.annotation.Bean;
+import org.springframework.context.annotation.Configuration;
+import org.springframework.data.mongodb.core.MongoTemplate;
+import uk.ac.ebi.eva.commons.models.mongo.entity.VariantDocument;
+import uk.ac.ebi.eva.pipeline.io.readers.VariantStatsReader;
+import uk.ac.ebi.eva.pipeline.parameters.ChunkSizeParameters;
+import uk.ac.ebi.eva.pipeline.parameters.DatabaseParameters;
+import uk.ac.ebi.eva.pipeline.parameters.InputParameters;
+
+import static uk.ac.ebi.eva.pipeline.configuration.BeanNames.VARIANT_STATS_READER;
+
+@Configuration
+public class VariantStatsReaderConfiguration {
+
+    @Bean(VARIANT_STATS_READER)
+    @StepScope
+    public ItemStreamReader<VariantDocument> variantStatsReader(DatabaseParameters databaseParameters,
+                                                                MongoTemplate mongoTemplate,
+                                                                InputParameters inputParameters,
+                                                                ChunkSizeParameters chunkSizeParameters) {
+
+        return new VariantStatsReader(databaseParameters, mongoTemplate, inputParameters.getStudyId(), chunkSizeParameters.getChunkSize());
+    }
+}

src/main/java/uk/ac/ebi/eva/pipeline/configuration/io/writers/VariantStatsWriterConfiguration.java

@@ -0,0 +1,37 @@
+/*
+ * Copyright 2024 EMBL - European Bioinformatics Institute
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *      http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+package uk.ac.ebi.eva.pipeline.configuration.io.writers;
+
+import org.springframework.batch.core.configuration.annotation.StepScope;
+import org.springframework.batch.item.ItemWriter;
+import org.springframework.context.annotation.Bean;
+import org.springframework.context.annotation.Configuration;
+import org.springframework.data.mongodb.core.MongoTemplate;
+import uk.ac.ebi.eva.commons.models.mongo.entity.VariantDocument;
+import uk.ac.ebi.eva.pipeline.io.writers.VariantStatsWriter;
+import uk.ac.ebi.eva.pipeline.parameters.DatabaseParameters;
+
+import static uk.ac.ebi.eva.pipeline.configuration.BeanNames.VARIANT_STATS_WRITER;
+
+@Configuration
+public class VariantStatsWriterConfiguration {
+
+    @Bean(VARIANT_STATS_WRITER)
+    @StepScope
+    public ItemWriter<VariantDocument> variantStatsWriter(DatabaseParameters databaseParameters, MongoTemplate mongoTemplate) {
+        return new VariantStatsWriter(databaseParameters, mongoTemplate);
+    }
+}

src/main/java/uk/ac/ebi/eva/pipeline/configuration/jobs/CalculateAndLoadStatisticsJobConfiguration.java

@@ -0,0 +1,64 @@
+/*
+ * Copyright 2024 EMBL - European Bioinformatics Institute
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *      http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+package uk.ac.ebi.eva.pipeline.configuration.jobs;
+
+import org.slf4j.Logger;
+import org.slf4j.LoggerFactory;
+import org.springframework.batch.core.Job;
+import org.springframework.batch.core.Step;
+import org.springframework.batch.core.configuration.annotation.EnableBatchProcessing;
+import org.springframework.batch.core.configuration.annotation.JobBuilderFactory;
+import org.springframework.beans.factory.annotation.Autowired;
+import org.springframework.beans.factory.annotation.Qualifier;
+import org.springframework.context.annotation.Bean;
+import org.springframework.context.annotation.Configuration;
+import org.springframework.context.annotation.Import;
+import org.springframework.context.annotation.Scope;
+import uk.ac.ebi.eva.pipeline.configuration.jobs.steps.CalculateAndLoadStatisticsStepConfiguration;
+import uk.ac.ebi.eva.pipeline.parameters.NewJobIncrementer;
+
+import static uk.ac.ebi.eva.pipeline.configuration.BeanNames.CALCULATE_AND_LOAD_STATISTICS_JOB;
+import static uk.ac.ebi.eva.pipeline.configuration.BeanNames.CALCULATE_AND_LOAD_STATISTICS_STEP;
+
+/**
+ * Configuration to run a full Statistics job: variantStatsFlow: statsCreate --> statsLoad
+ * <p>
+ * TODO add a new PopulationStatisticsJobParametersValidator
+ */
+@Configuration
+@EnableBatchProcessing
+@Import({CalculateAndLoadStatisticsStepConfiguration.class})
+public class CalculateAndLoadStatisticsJobConfiguration {
+
+    private static final Logger logger = LoggerFactory.getLogger(CalculateAndLoadStatisticsJobConfiguration.class);
+
+    @Autowired
+    @Qualifier(CALCULATE_AND_LOAD_STATISTICS_STEP)
+    private Step calculateAndLoadStatisticsStep;
+
+    @Bean(CALCULATE_AND_LOAD_STATISTICS_JOB)
+    @Scope("prototype")
+    public Job calculateAndLoadStatisticsJob(JobBuilderFactory jobBuilderFactory) {
+        logger.debug("Building '" + CALCULATE_AND_LOAD_STATISTICS_JOB + "'");
+
+        return jobBuilderFactory
+                .get(CALCULATE_AND_LOAD_STATISTICS_JOB)
+                .incrementer(new NewJobIncrementer())
+                .start(calculateAndLoadStatisticsStep)
+                .build();
+    }
+
+}

src/main/java/uk/ac/ebi/eva/pipeline/configuration/jobs/steps/CalculateAndLoadStatisticsStepConfiguration.java

@@ -0,0 +1,63 @@
+/*
+ * Copyright 2024 EMBL - European Bioinformatics Institute
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *      http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+package uk.ac.ebi.eva.pipeline.configuration.jobs.steps;
+
+import org.springframework.batch.core.Step;
+import org.springframework.batch.core.configuration.annotation.EnableBatchProcessing;
+import org.springframework.batch.core.configuration.annotation.StepBuilderFactory;
+import org.springframework.batch.core.step.tasklet.TaskletStep;
+import org.springframework.batch.item.ItemProcessor;
+import org.springframework.batch.item.ItemStreamReader;
+import org.springframework.batch.item.ItemWriter;
+import org.springframework.batch.repeat.policy.SimpleCompletionPolicy;
+import org.springframework.beans.factory.annotation.Qualifier;
+import org.springframework.context.annotation.Bean;
+import org.springframework.context.annotation.Configuration;
+import org.springframework.context.annotation.Import;
+import uk.ac.ebi.eva.commons.models.mongo.entity.VariantDocument;
+import uk.ac.ebi.eva.pipeline.configuration.ChunkSizeCompletionPolicyConfiguration;
+import uk.ac.ebi.eva.pipeline.configuration.io.readers.VariantStatsReaderConfiguration;
+import uk.ac.ebi.eva.pipeline.configuration.io.writers.VariantStatsWriterConfiguration;
+import uk.ac.ebi.eva.pipeline.configuration.jobs.steps.processors.VariantStatsProcessorConfiguration;
+
+import static uk.ac.ebi.eva.pipeline.configuration.BeanNames.CALCULATE_AND_LOAD_STATISTICS_STEP;
+import static uk.ac.ebi.eva.pipeline.configuration.BeanNames.VARIANT_STATS_PROCESSOR;
+import static uk.ac.ebi.eva.pipeline.configuration.BeanNames.VARIANT_STATS_READER;
+import static uk.ac.ebi.eva.pipeline.configuration.BeanNames.VARIANT_STATS_WRITER;
+
+
+@Configuration
+@EnableBatchProcessing
+@Import({VariantStatsReaderConfiguration.class, VariantStatsWriterConfiguration.class,
+        VariantStatsProcessorConfiguration.class, ChunkSizeCompletionPolicyConfiguration.class})
+public class CalculateAndLoadStatisticsStepConfiguration {
+
+    @Bean(CALCULATE_AND_LOAD_STATISTICS_STEP)
+    public Step calculateAndLoadStatisticsStep(
+            @Qualifier(VARIANT_STATS_READER) ItemStreamReader<VariantDocument> variantStatsReader,
+            @Qualifier(VARIANT_STATS_PROCESSOR) ItemProcessor<VariantDocument, VariantDocument> variantStatsProcessor,
+            @Qualifier(VARIANT_STATS_WRITER) ItemWriter<VariantDocument> variantStatsWriter,
+            StepBuilderFactory stepBuilderFactory,
+            SimpleCompletionPolicy chunkSizeCompletionPolicy) {
+        TaskletStep step = stepBuilderFactory.get(CALCULATE_AND_LOAD_STATISTICS_STEP)
+                .<VariantDocument, VariantDocument>chunk(chunkSizeCompletionPolicy)
+                .reader(variantStatsReader)
+                .processor(variantStatsProcessor)
+                .writer(variantStatsWriter)
+                .build();
+        return step;
+    }
+}

src/main/java/uk/ac/ebi/eva/pipeline/configuration/jobs/steps/processors/VariantStatsProcessorConfiguration.java

@@ -0,0 +1,35 @@
+/*
+ * Copyright 2024 EMBL - European Bioinformatics Institute
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *      http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+package uk.ac.ebi.eva.pipeline.configuration.jobs.steps.processors;
+
+import org.springframework.batch.core.configuration.annotation.StepScope;
+import org.springframework.batch.item.ItemProcessor;
+import org.springframework.context.annotation.Bean;
+import org.springframework.context.annotation.Configuration;
+import uk.ac.ebi.eva.commons.models.mongo.entity.VariantDocument;
+import uk.ac.ebi.eva.pipeline.io.processors.VariantStatsProcessor;
+
+import static uk.ac.ebi.eva.pipeline.configuration.BeanNames.VARIANT_STATS_PROCESSOR;
+
+@Configuration
+public class VariantStatsProcessorConfiguration {
+
+    @Bean(VARIANT_STATS_PROCESSOR)
+    @StepScope
+    public ItemProcessor<VariantDocument, VariantDocument> variantStatsProcessor() {
+        return new VariantStatsProcessor();
+    }
+}