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7/23/24 TODOs #95

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cmatKhan opened this issue Jul 23, 2024 · 1 comment
Open

7/23/24 TODOs #95

cmatKhan opened this issue Jul 23, 2024 · 1 comment
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@cmatKhan
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cmatKhan commented Jul 23, 2024

  1. Average the rank of a given gene across all McIsaac timepoints 15 to end. Reproduce the binning and make a boxplot that shows the 15 minute McIsaac vs binding and the rank averaged mcisaac vs the binding

  2. Use the Kemmeren data rather than the McIsaac 15 minutes

  3. Rank average the McIsaac rank averaged data and the Kemmeren ranks and plot vs binding

  4. For each TF binding data set, rank by poisson, rank by hypergeometric and rank by enrichment. Make a boxplot to describe distribution of the top rank. X-axis should be poisson, hypergeometric and enrichment. The question is, which of these methods yields a larger top rank on average?

  5. Include more of the TFs -- set all mitra lab data to data_passing for the time being, also include TFs with single data_usable = passing

@cmatKhan
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I'll take care of 5.

numbers 1 to 4 will take some database interaction -- let me know if/when you need help with that

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