Consider expanding wilms tumor label transfer #900
sjspielman
started this conversation in
Modify an existing analysis
Replies: 0 comments
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment
-
Existing analysis
This discussion pertains to the
cell-type-willms-tumor-06
andcell-type-wilms-tumor-14
modules.Details of modification
Both the
cell-type-willms-tumor-06
andcell-type-wilms-tumor-14
modules use the Stewart et al. fetal kidney reference to perform label transfer.Here are sources for data from that reference:
While looking into this reference in a bit more detail as part of #866, I noticed that there are additional label fields here:
cell_state
, which has valuesna
andproliferating
cell_type_ontology_term_id
, which has ontology IDs for cell typesauthor_cell_type
, which has a different version of cell types but I'm not 100% sure how this information was obtained (the originating paper is paywalled for me)If anyone wants to do further analysis on Wilms tumor samples with this reference, they might consider whether any of these labels would be useful. The ontology would be useful for putting things into prod and/or comparing more carefully among cell types related along a lineage, too.
This purpose of this discussion is therefore to surface this idea so we remember about these additional columns, for if/when these modules are updated in the future.
Describe your goals
Scientific literature
No response
Other details
No response
Beta Was this translation helpful? Give feedback.
All reactions